Menée à partir des données de 25 études portant sur 24 643 témoins et 10 283 patients atteints d'un cancer gastrique, cette méta-analyse évalue l'association entre l'utilisation de sel de table, l'apport total en sodium ou la consommation d'aliments riches en sel et le risque de développer la maladie

Salt intake and gastric cancer: a pooled analysis within the Stomach cancer Pooling (StoP) Project

Morais, Samantha ; Costa, Adriana ; Albuquerque, Gabriela ; Araújo, Natália ; Pelucchi, Claudio ; Rabkin, Charles S. ; Liao, Linda M. ; Sinha, Rashmi ; Zhang, Zuo-Feng ; Hu, Jinfu ; Johnson, Kenneth C. ; Palli, Domenico ; Ferraroni, Monica ; Bonzi, Rossella ; Yu, Guo-Pei ; López-Carrillo, Lizbeth ; Malekzadeh, Reza ; Tsugane, Shoichiro ; Hidaka, Akihisa ; Hamada, Gerson Shigueaki ; Zaridze, David ; Maximovitch, Dmitry ; Vioque, Jesús ; de la Hera, Manoli García ; Moreno, Víctor ; Vanaclocha-Espi, Mercedes ; Ward, Mary H. ; Pakseresht, Mohammadreza ; Hernández-Ramírez, Raúl Ulises ; López-Cervantes, Malaquias ; Pourfarzi, Farhad ; Mu, Lina ; Kurtz, Robert C. ; Boccia, Stefania ; Pastorino, Roberta ; Lagiou, Areti ; Lagiou, Pagona ; Boffetta, Paolo ; Camargo, M. Constanza ; Curado, Maria Paula ; Negri, Eva ; La Vecchia, Carlo ; Lunet, Nuno

Purpose: Previous studies show that consuming foods preserved by salting increases the risk of gastric cancer, while results on the association between total salt or added salt and gastric cancer are less consistent and vary with the exposure considered. This study aimed to quantify the association between dietary salt exposure and gastric cancer, using an individual participant data meta-analysis of studies participating in the Stomach cancer Pooling (StoP) Project. Methods: Data from 25 [...]

Menée au Canada auprès de 760 témoins et 190 patients atteints d'un cancer du poumon et n'ayant jamais fumé, cette étude analyse l'association entre des facteurs liés au mode de vie et le risque de développer la maladie

Lifestyle factors and lung cancer risk among never smokers in the Canadian Partnership for Tomorrow’s Health (CanPath)

Murphy, Rachel A. ; Darvishian, Maryam ; Qi, Jia ; Chen, Yixian ; Chu, Quincy ; Vena, Jennifer ; Dummer, Trevor J. B. ; Le, Nhu ; Sweeney, Ellen ; DeClercq, Vanessa ; Grandy, Scott A. ; Keats, Melanie R. ; Cui, Yunsong ; Awadalla, Philip ; Brenner, Darren R. ; Bhatti, Parveen

Background: Although smoking is the primary risk factor for lung cancer, 15–25% of lung cancers occur in never smokers. Emerging evidence suggests lifestyle factors are associated with lung cancer risk, but few studies among never smokers exist. Methods: A case–control study of never smokers within the Canadian Partnership for Tomorrow’s Health was conducted. At recruitment, participants provided data on lifestyle, health history and sociodemographic factors. Incident lung cancers were [...]

Cette étude passe en revue la littérature publiée jusqu'en août 2021 (27 articles) concernant l'association entre une infection à Chlamydia pneumoniae et le risque de cancer du poumon

Chlamydia pneumoniae infections and development of lung cancer: systematic review

Premachandra, Nadeesha Madushani ; Jayaweera, J. A. A. Sampath

Background: Chlamydia pneumoniae is an obligate intracellular pathogen and is a common cause of human respiratory diseases, including pneumonia. It has been already known to have a causal relationship with some chronic diseases such as chronic obstructive pulmonary disease, asthma, and atherosclerotic cardiovascular diseases. In this review, we aim to find out the association between C. pneumoniae infection and lung cancer. Methods: This is a systematic review on C. pneumoniae infection and the [...]

A partir d'une revue systématique de la littérature (24 études), cette méta-analyse évalue l'association entre cinq classes de médicaments antihypertenseurs (inhibiteurs de l'enzyme de conversion de l'angiotensine, inhibiteurs des récepteurs de l'angiotensine II, bêta-bloquants, inhibiteurs des canaux calciques et diurétiques) et le risque de cancer colorectal

Anti-hypertensive medications and risk of colorectal cancer: a systematic review and meta-analysis

Qi, Jia ; An, Ruona ; Bhatti, Parveen ; Spinelli, John J. ; Murphy, Rachel A.

Purpose: Antihypertensive medications may impact colorectal cancer risk. We conducted a systematic review and meta-analysis of associations, with colorectal cancer risk, of five classes of antihypertensive medications: angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), beta-blockers (BBs), calcium channel blockers (CCBs), and diuretics. Methods: A systematic search was conducted in MEDLINE, Embase, Web of Science, and the Cochrane library to identify [...]

Menée à partir de données 2005-2012 du registre suédois des médicaments prescrits à 5,7 millions de personnes, cette étude analyse l'association entre une utilisation de statines, de metformine et d'anti-inflammatoires non stéroïdiens (dont de faibles doses d'aspirine) et le risque de cancer des voies biliaires (160 cas)

Aspirin, Statins, Non-aspirin NSAIDs, Metformin, and the Risk of Biliary Cancer: A Swedish Population-Based Cohort Study

Marcano-Bonilla, Lorena ; Schleck, Cathy D. ; Harmsen, William S. ; Sadr-Azodi, Omid ; Borad, Mitesh J. ; Patel, Tushar ; Petersen, Gloria M. ; Therneau, Terry M. ; Roberts, Lewis R. ; Brusselaers, Nele

Chemoprevention for biliary tract cancers (BTC), which comprise intrahepatic cholangiocarcinoma (iCCA), extrahepatic cholangiocarcinoma (eCCA), and gallbladder cancer, is controversial. We examined associations between low-dose aspirin, statins, NSAIDs, and metformin with BTC risk.We used a population-based cohort of 5.7 million persons over age 18 without personal history of cancer (except nonmelanoma skin cancer), receiving at least one commonly prescribed drug between July 1, 2005, and [...]

A partir d'une revue systématique de la littérature publiée jusqu'en septembre 2020 (17 études, 3 121 femmes porteuses d'un variant pathogène BRCA dont 115 patientes atteintes d'un carcinome séreux intraépithélial des trompes), cette méta-analyse évalue le risque de carcinose péritonéale après une salpingo-ovariectomie prophylactique

Risk of Peritoneal Carcinomatosis After Risk-Reducing Salpingo-Oophorectomy: A Systematic Review and Individual Patient Data Meta-Analysis

Miranda P. Steenbeek ; Majke H.D. van Bommel ; Johan Bulten ; Julia A. Hulsmann ; Joep Bogaerts ; Christine Garcia ; Han T. Cun ; Karen H. Lu ; Heleen J. van Beekhuizen ; Lucas Minig ; Katja N. Gaarenstroom ; Marielle Nobbenhuis ; Mateja Krajc ; Vilius Rudaitis ; Barbara M. Norquist ; Elizabeth M. Swisher ; Marian J.E. Mourits ; Leon F.A.G. Massuger ; Nicoline Hoogerbrugge ; Rosella P.M.G. Hermens ; Joanna IntHout ; Joanne A. de Hullu

PURPOSE: After risk-reducing salpingo-oophorectomy (RRSO), BRCA1/2 pathogenic variant (PV) carriers have a residual risk to develop peritoneal carcinomatosis (PC). The etiology of PC is not yet clarified, but may be related to serous tubal intraepithelial carcinoma (STIC), the postulated origin for high-grade serous cancer. In this systematic review and individual patient data meta-analysis, we investigate the risk of PC in women with and without STIC at RRSO. METHODS: Unpublished data from [...]

Menée en Pologne auprès de 102 patientes atteintes d'une tumeur de l'ovaire à la limite de la malignité et à l'aide de données portant sur 1 743 témoins, cette étude analyse l'association entre des mutations de BRCA1, BRCA2, PALB2, RAD51C ou CHEK2 et le risque de développer la maladie

Association of recurrent mutations in BRCA1, BRCA2, RAD51C, PALB2, and CHEK2 with the risk of borderline ovarian tumor

Ogrodniczak, Alicja ; Menkiszak, Janusz ; Gronwald, Jacek ; Tomiczek-Szwiec, Joanna ; Szwiec, Marek ; Cybulski, Cezary ; Dębniak, Tadeusz ; Huzarski, Tomasz ; Tołoczko-Grabarek, Aleksandra ; Byrski, Tomasz ; Białkowska, Katarzyna ; Prajzendanc, Karolina ; Baszuk, Piotr ; Lubinski, Jan ; Jakubowska, Anna

Background: There are several genes associated with ovarian cancer risk. Molecular changes in borderline ovarian tumor (BOT) indicate linkage of this disease to type I ovarian tumors (low-grade ovarian carcinomas). This study determined the prevalence and association of mutations in BRCA1, BRCA2, PALB2, RAD51C, and CHEK2 with the risk of BOTs. Methods: The study group consisted of 102 patients with histologically confirmed BOT and 1743 healthy controls. In addition, 167 cases with ovarian [...]