Menée à partir de données portant sur 20 001 personnes (âge : 40-69 ans ; durée moyenne de suivi : 16 ans), cette étude analyse l'association entre une adhésion aux recommandations 2018 du "World Cancer Research Fund/American Institute for Cancer Research" et le risque de cancer (4 710 cas)

Adherence to 2018 WCRF/AICR cancer prevention recommendations and risk of cancer: the Melbourne Collaborative Cohort Study

Peng, Yang ; Bassett, Julie K. ; Hodge, Allison M. ; Melaku, Yohannes Adama ; Afshar, Nina ; Hopper, John L. ; Maclnnis, Robert J. ; Lynch, Brigid M. ; Smith-Warner, Stephanie A. ; Giles, Graham G. ; Milne, Roger L. ; Jayasekara, Harindra

Background: We examined associations between adherence to adaptations of the 2018 World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) cancer prevention recommendations and total, exposure-related and site-specific cancer risk. Methods: 20,001 participants aged 40–69 years at enrollment into the Melbourne Collaborative Cohort Study in 1990-94, who had diet, body size and lifestyle re-assessed in 2003-07 (‘baseline’), were followed-up through June-2021. We constructed [...]

A partir d'une revue systématique de la littérature publiée jusqu'en mai 2023 (6 études), cette méta-analyse évalue l'association entre une adhésion au régime méditerranéen et le risque d'adénome colorectal

Mediterranean diet and colorectal adenomas: a systematic review and meta-analysis of observational studies

Jafari Nasab, Saeede ; Clark, Cain C. T. ; Entezari, Mohammadhasan

Colorectal adenomas (CRAs) are epithelial lesions of the large bowel that can develop into colorectal cancer. Some studies have shown an inverse association of the Mediterranean diet (MED) with adenoma, but the extent of the association is equivocal. Owing to the lack of meta-analytical evidence in the literature, we sought to assess the association between MED and CRAs by conducting a systematic review and meta-analysis. A comprehensive systematic literature search of observational studies was [...]

Menée à l'aide de données de registres danois portant sur 1 909 531 personnes (âge : 40-70 ans ; durée moyenne de suivi : 18,2 ans), cette étude analyse l'association entre une utilisation à long terme d'aspirine et le risque de cancer, en fonction de la dose

Long-Term Aspirin Use and Cancer Risk: a 20-Year Cohort Study

Skriver, Charlotte ; Maltesen, Thomas ; Dehlendorff, Christian ; Skovlund, Charlotte Wessel ; Schmidt, Morten ; Sørensen, Henrik Toft ; Friis, Søren

Long-term use of aspirin has been shown to reduce colorectal cancer risk, but the association remains inconclusive for individual noncolorectal cancers. We examined the association between long-term aspirin use and cancer risk in Denmark.Using nationwide registries, we followed individuals 40-70 years at baseline (1 January 1997) for cancer diagnoses through 2018. We assessed low-dose (75-150 mg) aspirin use according to continuity, duration, and cumulative amount. Secondly, we explored [...]

A partir d'une revue de la littérature publiée jusqu'en février 2022 (11 essais randomisés, 92 550 patients), cette méta-analyse évalue l'association entre la dose d'aspirine utilisée et le risque de cancer colorectal

Aspirin chemoprevention in colorectal cancer: network meta-analysis of low, moderate, and high doses

Shah, D. ; Di Re, A. ; Toh, J. W. T.

BACKGROUND: Colorectal cancer is the third most common cancer, with nearly 2 million cases worldwide and just under 1 million deaths in 2020. Several trials have demonstrated that aspirin has the potential to reduce the incidence and/or recurrence of colorectal cancer; however, the optimal aspirin dose is unclear. METHODS: Relevant studies were identified by searching MEDLINE, Embase and the Cochrane Library from database inception to 2 February 2022. Data from RCTs in which the incidence of [...]

Mené en Californie sur 213 fumeurs souhaitant arrêter de fumer (âge moyen : 41,2 ans), cet essai randomisé évalue l'effet, sur la consommation tabagique, d'une application d'entraînement à la pleine conscience par la méditation

Mindfulness training app effect on a cigarette smoking quit attempt: Investigator-blinded 58-county RCT

Black, David S ; Kirkpatrick, Matthew G

Cigarette smoking is the leading cause of preventable cancers. A majority of the 34 million people who currently smoke report wanting to quit. Mindfulness training (MT) apps offer a guided telehealth intervention to foster individual's behavioral practice of meditation. We present the main outcomes of a parallel-group RCT that tested app-MT versus attention control on smoking behavior.We enrolled adult residents from across California who smoked daily and were willing to make a quit attempt [...]