A partir d'une analyse bibliométrique réalisée en janvier 2023, cette étude fait le point sur la recherche concernant l'association entre une exposition à la fumée de tabac ambiante et la santé des enfants

Environmental tobacco smoke and children’s health: a bibliometric and altmetric analysis of 100 most cited articles

Patil, Sneha S. ; Puttaswamy, Naveen ; Sarode, Sachin C. ; Sarode, Gargi S. ; Patil, Smita S. ; Cardenas, Andres ; Gandhirajan, Rajesh Kumar ; Balakrishnan, Kalpana

Background: Exposure to environmental tobacco smoke (ETS) is arguably the most ubiquitous and hazardous, even at very low levels, starting in early life. The objective of this study was to describe the state of research and future trends on ETS exposure and Children’s Health (CH) topics with bibliometrics and altmetrics. Methods: An electronic search was performed in Scopus database on January 31, 2023. Consensus was arrived on 100 most-cited articles by two reviewers. These papers were then [...]

Menée auprès de 266 666 personnes incluses dans la cohorte "EPIC" (durée médiane de suivi : 11,2 ans ; 60 % de femmes), cette étude analyse l'association entre la consommation de produits ultra-transformés et le risque de développer au moins 2 maladies chroniques (cancer, maladie cardiovasculaire, diabète)

Consumption of ultra-processed foods and risk of multimorbidity of cancer and cardiometabolic diseases: a multinational cohort study

Cordova, Reynalda ; Viallon, Vivian ; Fontvieille, Emma ; Peruchet-Noray, Laia ; Jansana, Anna ; Wagner, Karl-Heinz ; Kyrø, Cecilie ; Tjønneland, Anne ; Katzke, Verena ; Bajracharya, Rashmita ; Schulze, Matthias B. ; Masala, Giovanna ; Sieri, Sabina ; Panico, Salvatore ; Ricceri, Fulvio ; Tumino, Rosario ; Boer, Jolanda M. A. ; Verschuren, W. M. Monique ; van der Schouw, Yvonne T. ; Jakszyn, Paula ; Redondo-Sánchez, Daniel ; Amiano, Pilar ; Huerta, José María ; Guevara, Marcela ; Borné, Yan ; Sonestedt, Emily ; Tsilidis, Konstantinos K. ; Millett, Christopher ; Heath, Alicia K. ; Aglago, Elom K. ; Aune, Dagfinn ; Gunter, Marc J. ; Ferrari, Pietro ; Huybrechts, Inge ; Freisling, Heinz

Background: It is currently unknown whether ultra-processed foods (UPFs) consumption is associated with a higher incidence of multimorbidity. We examined the relationship of total and subgroup consumption of UPFs with the risk of multimorbidity defined as the co-occurrence of at least two chronic diseases in an individual among first cancer at any site, cardiovascular disease, and type 2 diabetes. Methods: This was a prospective cohort study including 266,666 participants (60% women) free of [...]

Menée auprès de 948 174 personnes ayant subi un examen tomodensitométrique avant l'âge de 22 ans, cette étude analyse l'association entre la dose de rayonnements reçue lors de cet examen et le risque d'hémopathie maligne (790 cas)

Risk of hematological malignancies from CT radiation exposure in children, adolescents and young adults

Bosch de Basea Gomez, Magda ; Thierry-Chef, Isabelle ; Harbron, Richard ; Hauptmann, Michael ; Byrnes, Graham ; Bernier, Maria-Odile ; Le Cornet, Lucian ; Dabin, Jérémie ; Ferro, Gilles ; Istad, Tore S. ; Jahnen, Andreas ; Lee, Choonsik ; Maccia, Carlo ; Malchair, Françoise ; Olerud, Hilde ; Simon, Steven L. ; Figuerola, Jordi ; Peiro, Anna ; Engels, Hilde ; Johansen, Christoffer ; Blettner, Maria ; Kaijser, Magnus ; Kjaerheim, Kristina ; Berrington de Gonzalez, Amy ; Journy, Neige ; Meulepas, Johanna M. ; Moissonnier, Monika ; Nordenskjold, Arvid ; Pokora, Roman ; Ronckers, Cecile ; Schüz, Joachim ; Kesminiene, Ausrele ; Cardis, Elisabeth

Over one million European children undergo computed tomography (CT) scans annually. Although moderate- to high-dose ionizing radiation exposure is an established risk factor for hematological malignancies, risks at CT examination dose levels remain uncertain. Here we followed up a multinational cohort (EPI-CT) of 948,174 individuals who underwent CT examinations before age 22 years in nine European countries. Radiation doses to the active bone marrow were estimated on the basis of body part [...]

Menée à l'aide d'une méthode de randomisation mendélienne et de données pangénomiques portant sur 377 277 patients atteints d'un cancer du pancréas, cette étude analyse l'association entre le microbiote intestinal et le risque de développer la maladie

Causal effect between gut microbiota and pancreatic cancer: a two-sample Mendelian randomization study

Jiang, Zhichen ; Mou, Yiping ; Wang, Huiju ; Li, Li ; Jin, Tianyu ; Wang, He ; Liu, Mingyang ; Jin, Weiwei

Background: Gut microbiota (GM) comprises a vast and diverse community of microorganisms, and recent studies have highlighted the crucial regulatory roles of various GM and their secreted metabolites in pancreatic cancer (PC). However, the causal relationship between GM and PC has yet to be confirmed. Methods: In the present study, we used two-sample Mendelian randomization (MR) analysis to investigate the causal effect between GM and PC, with genome-wide association study (GWAS) from MiBioGen [...]

Menée à l'aide de données taïwanaises 2002-2011 portant sur 1 024 témoins et 1 024 patientes atteintes d'un adénocarcinome pulmonaire et n'ayant jamais fumé (âge moyen : 59,6 ans), cette étude analyse l'association entre un score de risque polygénique, une exposition à la fumée de tabac ambiante et le risque de développer la maladie

Polygenic Risk Score, Environmental Tobacco Smoke, and Risk of Lung Adenocarcinoma in Never-Smoking Women in Taiwan

Blechter, Batel ; Chien, Li-Hsin ; Chen, Tzu-Yu ; Chang, I-Shou ; Choudhury, Parichoy Pal ; Hsiao, Chin-Fu ; Shu, Xiao-Ou ; Wong, Jason Y. Y. ; Chen, Kuan-Yu ; Chang, Gee-Chen ; Tsai, Ying-Huang ; Su, Wu-Chou ; Huang, Ming-Shyan ; Chen, Yuh-Min ; Chen, Chih-Yi ; Hung, Hsiao-Han ; Hu, Jia-Wei ; Shi, Jianxin ; Zheng, Wei ; Rositch, Anne F. ; Chen, Chien-Jen ; Chatterjee, Nilanjan ; Yang, Pan-Chyr ; Rothman, Nathaniel ; Hsiung, Chao Agnes ; Lan, Qing

Estimating absolute risk of lung cancer for never-smoking individuals is important to inform lung cancer screening programs.To integrate data on environmental tobacco smoke (ETS), a known lung cancer risk factor, with a polygenic risk score (PRS) that captures overall genetic susceptibility, to estimate the absolute risk of lung adenocarcinoma (LUAD) among never-smokers in Taiwan.The analyses were conducted in never-smoking women in the Taiwan Genetic Epidemiology Study of Lung Adenocarcinoma, [...]

Menée aux Etats-Unis à l'aide de données 2002-2018 portant sur 85 000 personnes (âge médian : 51 ans ; 64 % de femmes), cette étude analyse l'association entre un diabète de type 2 et le risque de cancer colorectal en fonction de l'origine ethnique

Type 2 Diabetes and Colorectal Cancer Risk

Lawler, Thomas ; Walts, Zoe L. ; Steinwandel, Mark ; Lipworth, Loren ; Murff, Harvey J. ; Zheng, Wei ; Warren Andersen, Shaneda

Type 2 diabetes and colorectal cancer (CRC) disproportionately burden indviduals of low socioeconomic status and African American race. Although diabetes is an emerging CRC risk factor, associations between diabetes and CRC in these populations are understudied.To determine if diabetes is associated with CRC risk in a cohort representing understudied populations.This cohort study uses data from the prospective Southern Community Cohort Study in the US, which recruited from 2002 to 2009 and [...]

Menée à partir de données de la "UK Biobank" portant sur 198 748 femmes (âge : 40-69 ans ; durée moyenne de suivi : 11,4 ans), cette étude analyse l'association entre un syndrome métabolique et le risque de carcinome canalaire in situ (1 251 cas)

Metabolic syndrome and the risk of ductal carcinoma in situ of the breast in the UK Biobank

Peila, Rita ; Rohan, Thomas E.

Background: Metabolic syndrome (MetS), defined by the presence of three of more metabolic dysregulations such as hyperlipidemia, hyperinsulinemia, central obesity, and hypertension, has been associated with increased risk of cardiovascular disease, diabetes, and various cancers, including invasive breast cancer (IBC). Whether MetS is a risk factor for ductal carcinoma in situ of the breast (DCIS), a non-obligate precursor of IBC, remains unknown. Methods: A total of 198,748 women aged 40–69 [...]

A partir d'une revue de la littérature, cette étude analyse l'association entre le microbiome mammaire et le risque de cancer du sein ainsi que sa progression

The breast microbiome in breast cancer risk and progression: a narrative review

Peters, Brandilyn A. ; Kelly, Libusha ; Wang, Tao ; Loudig, Olivier ; Rohan, Thomas E.

A decade ago, studies in human populations first revealed the existence of a unique microbial community in the breast, a tissue historically viewed as sterile, with microbial origins seeded through the nipple and/or translocation from other body sites. Since then, research efforts have been made to characterize the microbiome in healthy and cancerous breast tissues. The purpose of this review is to summarize the current evidence for the association of the breast microbiome with breast cancer [...]

Menée à partir de données de 21 études asiatiques portant au total sur 905 530 personnes, cette étude analyse l'association entre l'indice de masse corporelle et le risque de cancer des voies biliaires ainsi que la mortalité spécifique, en fonction du sexe et de le présence de calculs biliaires

Obesity is associated with biliary tract cancer mortality and incidence: A pooled analysis of 21 cohort studies in the Asia Cohort Consortiumc

Oze, Isao ; Ito, Hidemi ; Koyanagi, Yuriko N. ; Abe, Sarah Krull ; Rahman, Md. Shafiur ; Islam, Md. Rashedul ; Saito, Eiko ; Gupta, Prakash C. ; Sawada, Norie ; Tamakoshi, Akiko ; Shu, Xiao-Ou ; Sakata, Ritsu ; Malekzadeh, Reza ; Tsuji, Ichiro ; Kim, Jeongseon ; Nagata, Chisato ; You, San-Lin ; Park, Sue K. ; Yuan, Jian-Min ; Shin, Myung-Hee ; Kweon, Sun-Seog ; Pednekar, Mangesh S. ; Tsugane, Shoichiro ; Kimura, Takashi ; Gao, Yu-Tang ; Cai, Hui ; Pourshams, Akram ; Lu, Yukai ; Kanemura, Seiki ; Wada, Keiko ; Sugawara, Yumi ; Chen, Chien-Jen ; Chen, Yu ; Shin, Aesun ; Wang, Renwei ; Ahn, Yoon-Ok ; Shin, Min-Ho ; Ahsan, Habibul ; Boffetta, Paolo ; Chia, Kee Seng ; Qiao, You-Lin ; Rothman, Nathaniel ; Zheng, Wei ; Inoue, Manami ; Kang, Daehee ; Matsuo, Keitaro

Body fatness is considered a probable risk factor for biliary tract cancer (BTC), whereas cholelithiasis is an established factor. Nevertheless, although obesity is an established risk factor for cholelithiasis, previous studies of the association of body mass index (BMI) and BTC did not take the effect of cholelithiasis fully into account. To better understand the effect of BMI on BTC, we conducted a pooled analysis using population-based cohort studies in Asians. In total, 905 530 subjects [...]