Menée à l'aide de données de la "UK Biobank" portant sur 114 217 personnes (durée médiane de suivi : 9,4 ans), cette étude analyse l'association entre l'apport total en protéines, en protéines laitières ou en calcium et le risque de cancer du côlon-rectum (1 193 cas), du sein (2 024 cas) ou de la prostate (2 422 cas)

Associations of intakes of total protein, protein from dairy sources, and dietary calcium with risks of colorectal, breast, and prostate cancer: a prospective analysis in UK Biobank

Watling, Cody Z. ; Kelly, Rebecca K. ; Dunneram, Yashvee ; Knuppel, Anika ; Piernas, Carmen ; Schmidt, Julie A. ; Travis, Ruth C. ; Key, Timothy J. ; Perez-Cornago, Aurora

Background: Evidence concerning intakes of protein or sources of dairy protein and risks of colorectal, breast, and prostate cancers is inconclusive. Methods: Using a subsample of UK Biobank participants who completed ≥2 (maximum of 5) 24-h dietary assessments, we estimated intakes of total protein, protein from total dairy products, milk, and cheese, and dietary calcium in 114,217 participants. Hazard ratios (HRs) and 95% confidence intervals (CI) were estimated using multivariable-adjusted [...]

Menée à l'aide de données portant sur 8 128 témoins et 2 610 enfants atteints d'une tumeur cérébrale, cette étude analyse l'association entre l'allaitement maternel et l'incidence de la maladie pendant l'enfance

Breastfeeding and risk of childhood brain tumors: a report from the Childhood Cancer and Leukemia International Consortium

Schraw, Jeremy M. ; Petridou, Eleni Th ; Bonaventure, Audrey ; Dockerty, John D. ; Karalexi, Maria ; Ntzani, Evangelia ; Infante-Rivard, Claire ; Clavel, Jacqueline ; Bracci, Paige M. ; McKean-Cowdin, Roberta ; Roman, Eve ; Kane, Eleanor ; Erdmann, Friederike ; Schüz, Joachim ; Mueller, Beth A. ; Scheurer, Michael E.

Purpose: Studies report mixed findings regarding the association of breastfeeding with childhood brain tumors (CBT), the leading causes of cancer-related mortality in young people. Our objective was to determine whether breastfeeding is associated with CBT incidence. Methods: We pooled data on N = 2610 cases with CBT (including 697 cases with astrocytoma, 447 cases with medulloblastoma/primitive neuroectodermal tumor [PNET], 167 cases with ependymoma) and N = 8128 age- and sex-matched controls [...]

Menée à partir de données de 3 cohortes du consortium "AGRICOH" portant sur 316 270 agriculteurs, cette étude internationale analyse l'association entre l'utilisation de 22 composés actifs ou de 13 groupes chimiques et l'incidence du lymphome de Hodgkin (91 cas)

Exposure to pesticides and risk of Hodgkin lymphoma in an international consortium of agricultural cohorts (AGRICOH)

Kim, Joanne ; Leon, Maria E. ; Schinasi, Leah H. ; Baldi, Isabelle ; Lebailly, Pierre ; Freeman, Laura E. Beane ; Nordby, Karl-Christian ; Ferro, Gilles ; Monnereau, Alain ; Brouwer, Maartje ; Kjaerheim, Kristina ; Hofmann, Jonathan N. ; Straif, Kurt ; Kromhout, Hans ; Schüz, Joachim ; Togawa, Kayo

Purpose: Some pesticides may increase the risk of certain lymphoid malignancies, but few studies have examined Hodgkin lymphoma (HL). In this exploratory study, we examined associations between agricultural use of 22 individual active ingredients and 13 chemical groups and HL incidence. Methods: We used data from three agricultural cohorts participating in the AGRICOH consortium: the French Agriculture and Cancer Cohort (2005–2009), Cancer in the Norwegian Agricultural Population (1993–2011), [...]

Menée à partir de données de 6 cohortes européennes portant sur 302 493 personnes (durée moyenne de suivi : 18,2 ans), cette étude analyse l'association entre une exposition résidentielle au dioxyde d'azote, aux particules fines (PM2.5), au carbone noir, à l'ozone et à huit composants élémentaires des PM2.5 (cuivre, fer, potassium, nickel, soufre, silicium, vanadium et zinc) et le risque de tumeur du système nerveux central

Long-term air pollution exposure and malignant intracranial tumours of the central nervous system: a pooled analysis of six European cohorts

Hvidtfeldt, Ulla Arthur ; Chen, Jie ; Rodopoulou, Sophia ; Strak, Maciej ; de Hoogh, Kees ; Andersen, Zorana J. ; Bellander, Tom ; Brandt, Jørgen ; Fecht, Daniela ; Forastiere, Francesco ; Gulliver, John ; Hertel, Ole ; Hoffmann, Barbara ; Katsouyanni, Klea ; Ketzel, Matthias ; Leander, Karin ; Magnusson, Patrik K. E. ; Nagel, Gabriele ; Pershagen, Göran ; Rizzuto, Debora ; Samoli, Evangelia ; So, Rina ; Stafoggia, Massimo ; Tjønneland, Anne ; Weinmayr, Gudrun ; Wolf, Kathrin ; Zhang, Jiawei ; Zitt, Emanuel ; Brunekreef, Bert ; Hoek, Gerard ; Raaschou-Nielsen, Ole

Background: Risk factors for malignant tumours of the central nervous system (CNS) are largely unknown. Methods: We pooled six European cohorts (N = 302,493) and assessed the association between residential exposure to nitrogen dioxide (NO2), fine particles (PM2.5), black carbon (BC), ozone (O3) and eight elemental components of PM2.5 (copper, iron, potassium, nickel, sulfur, silicon, vanadium, and zinc) and malignant intracranial CNS tumours defined according to the International [...]

Menée aux Pays-Bas sur la période 1965-2013 auprès de 3 077 hommes ayant survécu 5 ans à un lymphome hodgkinien (durée médiane de suivi : 20 ans), cette étude multicentrique évalue le risque de cancer du sein lié au traitement du lymphome

Risk of male breast cancer after Hodgkin lymphoma

de Vries, Simone ; Krul, Inge ; Schaapveld, Michael ; Janus, Cecile M.P. ; Rademakers, Saskia E. ; Roesink, Judith M. ; Nijziel, Marten R. ; Bilgin, Yavuz M. ; Aleman, Berthe M.P. ; van Leeuwen, Flora E.

Female Hodgkin lymphoma (HL) survivors treated with chest radiotherapy have a strongly increased risk of breast cancer (BC), but the treatment-specific risk of BC in male HL survivors has not been evaluated. We assessed BC risk in a cohort of 3,077 male five-year HL survivors treated at age ≤51 years in 20 Dutch hospitals between 1965- 2013. We estimated standardized incidence ratios (SIRs), absolute excess risks per 10,000 person-years, and cumulative BC incidences. After a median follow-up of [...]

A partir d'une revue systématique de la littérature publiée jusqu'en juin 2023 (9 articles), cette étude analyse l'association réciproque entre des maladies auto-immunes et une leucémie infantile

Dual direction associations between common autoimmune diseases and leukemia among children and young adults: A systematic review

Ventelä, Julia ; Alanko, Anni ; Auvinen, Anssi ; Lohi, Olli ; Nikkilä, Atte

Background: Childhood leukemia and many autoimmune (AI) diseases are severe pediatric conditions with lifelong consequences. AI diseases form a heterogeneous disease group affecting about 5 % of children worldwide, while leukemia is the most common malignancy among children aged 0–14 years. The timing and similarities in suggested inflammatory and infectious triggers of AI disease and leukemia have raised a question whether the diseases share common etiological origins. We conducted a [...]