Menée par enquête dans 13 pays européens auprès de 24 733 participants atteints d'un cancer (549 répondants), cette étude analyse l'effet, sur leurs activités de la vie quotidienne, d'une douleur neuropathique liée à la maladie et analyse la prise en charge de cette douleur

Diagnosis, management and impact on patients' lives of cancer-related neuropathic pain (CRNP): A European survey

Dupoiron, Denis ; Brill, Silviu ; Eeltink, Corien ; Barragán, Begoña ; Bell, Dany ; Petersen, Gudula ; Eerdekens, Mariëlle ; Ryan, Deirdre ; Rakuša, Martin

Objective : This study assessed the impact of cancer-related neuropathic pain (CRNP) on patients and the importance of the patient–healthcare professional (HCP) relationship in diagnosis and management. Methods : A quantitative online survey was conducted involving adult patients from 13 European countries who had been diagnosed with treatable cancer and experienced symptoms of peripheral neuropathy. Results : Of 24,733 screened respondents, 549 eligible persons met the inclusion criteria and [...]

Menée en Suède à partir de données portant sur 616 patients ayant survécu à un cancer de l'oesophage traité par chirurgie entre 2001 et 2005, cette étude de cohorte prospective identifie les facteurs associés à leur qualité de vie 15 ans après le traitement chirurgical

Health-related quality of life 15 years after oesophageal cancer surgery: a prospective nationwide cohort study

Schandl, Anna ; Cheng, Zhao ; Johar, Asif ; Lagergren, Pernilla

Purpose : We aimed to study oesophageal cancer survivors’ health-related quality of life (HRQL) 15 years after surgery and to identify factors related to reduced HRQL. Methods : A nationwide, prospective cohort study enrolling 616 patients who underwent open oesophageal cancer surgery in Sweden between April 2, 2001, and December 21, 2005. HRQL was evaluated by questionnaires 15 years after surgery. HRQL data for the 15-year survivors were individually matched for age, sex and comorbidity by [...]

Menée au Brésil par questionnaire auprès de 100 aidants familiaux de patients atteints d'un cancer de la tête et du cou recevant des soins palliatifs, cette étude analyse les facteurs associés à la qualité de vie des aidants et évalue l'association entre leur qualité de vie et la survie du patient

Quality of life of family caregivers and survival of head and neck cancer patients in palliative care

Pequeno, Daniel Paixão ; Carron, Juliana ; Gaspar, Karla Cristina ; Lima, Carmen Silvia Passos ; Lourenço, Gustavo Jacob

Objective : The aim of this study is to assess the effect of sociodemographic and genetic features on the quality of life (QoL) of family caregivers (FCGs) of patients with head and neck cancer (HNC) in palliative care (PC) and the effect of QoL of FCGs on patients' survival. Methods : A questionnaire was applied to obtain sociodemographic information of 100 FCGs of patients with HNC in PC. The WHOQoL-bref questionnaire was used to measure QoL. Genotypes were identified using real-time PCR. [...]

A partir d'une revue systématique de la littérature publiée entre 2010 et 2021 (10 études, 6 605 patients), cette méta-analyse évalue les causes de décès des patients atteints d'un cancer et souffrant de septicémie et/ou d'un choc septique

All-cause mortality in cancer patients treated for sepsis in intensive care units: a systematic review and meta-analysis

Nazer, Lama ; Lopez-Olivo, Maria A. ; Cuenca, John A. ; Awad, Wedad ; Brown, Anne Rain ; Abusara, Aseel ; Sirimaturos, Michael ; Hicklen, Rachel S. ; Nates, Joseph L.

Purpose : Sepsis is a common complication in patients with cancer, but studies evaluating the outcomes of critically ill cancer patients with sepsis on a global scale are limited. We aimed to summarize the existing evidence on mortality rates in this patient population. Methods : Prospective and retrospective observational studies evaluating critically ill adult cancer patients with sepsis, severe sepsis, and/or septic shock were included. Studies published from January 2010 to September 2021 [...]

Menée aux Etats-Unis à partir de données portant sur 23 926 patients atteints d'un cancer lié à l'obésité et inclus dans des essais cliniques spécifiques de phase II ou III entre 1986 et 2016 (âge médian : 58 ans), cette étude de cohorte analyse la prévalence d'une obésité au moment du diagnostic de cancer ou de l'inclusion dans les essais

Trends in Obesity Prevalence Among Patients Enrolled in Clinical Trials for Obesity-Related Cancers, 1986 to 2016

Vaidya, Riha ; Till, Cathee ; Greenlee, Heather ; Hershman, Dawn L. ; Unger, Joseph M.

Importance : Obesity rates have risen in the United States since the 1980s. Several studies have shown links between obesity and the incidence of specific cancer types, but none have systematically examined obesity prevalence at the time of cancer diagnosis, or among clinical trial participants, all of which may affect clinical outcomes. Objective : To examine the prevalence of obesity and, separately, overweight and obesity over 30 years among patients with cancer enrolled in clinical [...]

A partir d'une revue systématique de la littérature (35 études, 11 396 patients), cette méta-analyse évalue la prévalence d'une dépression chez les aidants de patients atteints d'un cancer

Depression among caregivers of cancer patients: Updated systematic review and meta-analysis

Bedaso, Asres ; Dejenu, Getiye ; Duko, Bereket

Background : It is imperative to provide care for patients with terminal illnesses such as cancer, though it demands time, financial resources and other unmet needs. Subsequently, caregivers might be exposed to psychological stress and other mental health problems. Previous meta-analysis finding shows caregivers of cancer patient suffer from depression. During the past four years, there has been a considerable increase in the number of newly studies, and we therefore intended to update this [...]

A partir d'une revue systématique de la littérature (21 études, 2 079 patientes), cette méta-analyse évalue l'effet, sur la fatigue et la santé psychologique des patientes atteintes d'un cancer, des interventions basées sur le concept de la pleine conscience

Effects of mindfulness-based interventions on fatigue and psychological wellbeing in women with cancer: A systematic review and meta-analysis of randomised control trials

McCloy, Kairen ; Hughes, Ciara ; Dunwoody, Dr Lynn ; Marley, Dr Joanne ; Gracey, Dr Jackie

Background : Cancer diagnosis and treatment can cause fatigue, stress and anxiety which can have a detrimental effect on patients, families and the wider community. Mindfulness-based interventions appear to have positive effects on managing these cancer-related symptoms. Objective : To investigate the efficacy of mindfulness on cancer related fatigue (CRF) and psychological well-being in female cancer patients. Methods : Five databases (CINHAL, Ovid Medline, Ovid Psych Info, Scopus, and [...]

Menée aux Etats-Unis, cette étude analyse l'intérêt, dans le cadre d'un parcours de soins coordonné, d'une intervention pédagogique pour permettre aux aidants familiaux de patients atteints d'un cancer d'identifier et d'utiliser les ressources en soutien social

Training cancer caregiver navigators: experiences from implementing the eSNAP and caregiver navigator intervention

Reblin, Maija ; D’Almeida, Heraldo ; Barrios-Monroy, Veronica ; McCormick, Rachael ; Rodríguez, Laura ; Walters, Kerie ; Sutton, Steven K. ; Zebrack, Bradley ; Forsyth, Peter ; Byrne, Margaret M. ; Wells, Kristen J.

Patient navigation is increasingly common in cancer care. While navigation programs often involve informal family caregivers, few navigation interventions specifically target the family caregiver. We developed the eSNAP and Caregiver Navigator Intervention to help cancer family caregivers identify and capitalize on informal and formal social support resources. While the skill set for patient navigators may be adequate for supporting caregivers, other skills and areas of knowledge expertise are [...]

A partir d'une revue systématique de la littérature publiée entre 2010 et 2021 (15 études), cette étude analyse l'information pédagogique destinée aux patientes souffrant d'un lymphoedème lié à un cancer du sein et l'intérêt de cette information pour améliorer leur qualité de vie

Patient education for breast cancer–related lymphedema: a systematic review

Perdomo, Marisa ; Davies, Claire ; Levenhagen, Kimberly ; Ryans, Kathryn ; Gilchrist, Laura

Purpose : The aim was to identify the impact of the (a) components of breast cancer–related lymphedema (BCRL) educational content, (b) modes of education, and (c) timing of education on arm volume, quality of life, function, complications associated with BCRL, adherence to interventions, and knowledge acquisition in individuals diagnosed with breast cancer (BC). Methods : This review followed the Preferred Reported Items for Systematic Review and Meta-analysis (PRISMA) guidelines (PROSPERO [...]

Menée aux Etats-Unis par enquête auprès de 184 participants (70% de médecins), cette étude analyse l'utilisation de la cryothérapie et d'une thérapie par compression pour prévenir une neuropathie périphérique induite par la chimiothérapie chez des patients atteints d'un cancer

A global survey on the utilization of cryotherapy and compression therapy for the prevention of chemotherapy-induced peripheral neuropathy

Chan, Alexandre ; Elsayed, Amna ; Ng, Ding Quan ; Ruddy, Kathryn ; Loprinzi, Charles ; Lustberg, Maryam

Background : Chemotherapy-induced peripheral neuropathy (CIPN) is a serious side effect that is highly prevalent among cancer patients undergoing chemotherapy. There is a growing use of cryotherapy (CryTx) and compression therapy (ComTx) to prevent CIPN at cancer centers worldwide. In this study, we examined the awareness and recommendation of these modalities and evaluated factors associated with awareness. In addition, we investigated the type of technology utilized, barriers to [...]

Menée auprès de 9 553 patients atteints d'un cancer et pris en charge en ambulatoire (4 117 répondants), cette étude rétrospective analyse les facteurs associés à la déclaration de leurs symptômes et de leurs besoins en soins dans un outil électronique dédié, puis évalue l'impact de cette déclaration sur les admissions en services d'urgence et sur les hospitalisations

Symptoms and Needs Monitoring in Diverse Ambulatory Oncology Patients: Usage Characteristics and Impact on Emergency Room Visits and Hospitalization

Akina Natori ; Vandana Devika Sookdeo ; Tulay Koru-Sengul ; Matthew Schlumbrecht ; Carmen L. Calfa ; Jessica Maclntyre ; Roberto M. Benzo ; Patricia I. Moreno ; Tracy E. Crane ; Sofia F. Garcia ; Frank J. Penedo

PURPOSE : Symptoms and needs monitoring using patient-reported outcomes (PRO) is associated with improved clinical outcomes in cancer care. However, these improvements have been observed predominantly in non-Hispanic White patients using English assessments with high completion rates. The documented impact of such monitoring on system-level outcomes including emergency room (ER) visits and hospitalizations remains limited. We explored factors affecting the completion of PRO measures and [...]

Cette étude analyse l'intérêt de la traduction et de l'adaptation, dans 6 pays européens, d'une intervention psycho-pédagogique américaine pour aider les patients atteints d'un cancer et leurs aidants familiaux

Systematic translation and adaptation of the FOCUS program, a USA-based supportive intervention for persons with cancer and their family caregivers, for use in six European countries

van der Wel, Maaike ; van der Smissen, Doris ; Dierickx, Sigrid ; Cohen, Joachim ; Hudson, Peter ; De Vleminck, Aline ; Tutt, Lydia ; Scott, David ; Di Leo, Silvia ; Arnfeldt, Caroline Moeller ; Jordan, Catherine ; Northouse, Laurel ; Rietjens, Judith ; van der Heide, Agnes ; Witkamp, Erica

Purpose : Having advanced cancer presents many challenges for patients and family caregivers. The FOCUS program is a psychoeducational nurse-led intervention, developed in the USA, to support dyads of patients with cancer and their family caregivers to live with the illness. The program includes a conversation manual and information resources for dyads. We aimed to develop a version of the program for dyads facing advanced cancer in six European countries. Method : The Participatory and [...]