Menée en Norvège sur la période 1996-2014 auprès de 66 233 femmes (durée médiane de suivi : 14,2 ans), cette étude analyse l'effet d'une amélioration du mode de vie à l'âge adulte sur le risque de cancer (6 384 cas)

Overall lifestyle changes in adulthood are associated with cancer incidence in the Norwegian Women and Cancer Study (NOWAC) – a prospective cohort study

Chen, Sairah L. F. ; Nøst, Therese H. ; Botteri, Edoardo ; Ferrari, Pietro ; Braaten, Tonje ; Sandanger, Torkjel M. ; Borch, Kristin B.

Background: Cancer is a leading cause of premature death worldwide and incidence is expected to rise in the coming decades. Many cohort studies, measuring lifestyle factors at one time-point, have observed that overall healthy lifestyles were inversely related to cancer incidence. However, there is little knowledge on the impact of lifestyle modification within adulthood. Methods: Using the Norwegian Women and Cancer study, two repeated self-reported assessments of lifestyle behaviours were [...]

Menée aux Etats-Unis à partir de données d'enquêtes portant sur 19 824 participants, cette étude analyse l'association entre la réception de bons de réduction pour l'achat de cigarettes et le changement de statut tabagique

Cumulative cigarette discount coupon exposure and trajectories of cigarette smoking: a longitudinal analysis in US adults

Hamilton-Moseley, Kristen R ; McNeel, Timothy S ; Choi, Kelvin

Introduction: Exposure to cigarette discount coupons is associated with short-term increase in cigarette smoking; however, long-term impact is unclear. This study examined associations of cumulative exposure to cigarette coupons with trajectories of cigarette smoking in US adults. Methods: Data were from the US Population Assessment of Tobacco and Health Study Adult Surveys (n=19 824; waves 2–5). We examined the number of waves participants received cigarette discount coupons/promotions during [...]

Menée en Russie sur la période 2007-2020 auprès de 212 patients fumeurs atteints d'un carcinome à cellules rénales (durée médiane de suivi : 8,2 ans), cette étude analyse l'effet, sur la survie et la mortalité, du sevrage tabagique après le diagnostic

Smoking Cessation After Diagnosis of Kidney Cancer Is Associated With Reduced Risk of Mortality and Cancer Progression: A Prospective Cohort Study

Mahdi Sheikh ; Anush Mukeriya ; Hana Zahed ; Xiaoshuang Feng ; Hilary A. Robbins ; Oxana Shangina ; Vsevolod Matveev ; Paul Brennan ; David Zaridze

PURPOSE: To investigate whether postdiagnosis smoking cessation may affect the risk of death and disease progression in patients with renal cell carcinoma (RCC) who smoked at the time of diagnosis. METHODS: Two hundred twelve patients with primary RCC were recruited between 2007 and 2016 from the Urological Department in N.N. Blokhin National Medical Research Center of Oncology, Moscow, Russia. Upon enrollment, a structured questionnaire was completed, and the patients were followed annually [...]

Menée à l'aide de données 1988-2019 de registres coréens portant sur 9 246 personnes (âge moyen : 52,5 ans ; 63,8 % de femmes ; durée médiane de suivi : 7,8 ans), cette étude analyse l'association entre l'apport alimentaire total en fibres et le risque de cancer gastro-intestinal (163 cas)

Association of Dietary Fiber Intake With Gastrointestinal Tract Cancer Among Korean Adults

Jun, Shinyoung ; Lee, Jeonghee ; Kim, Jeongseon

Epidemiological studies have suggested a beneficial effect of dietary fiber on gastrointestinal tract cancers (GICs). In particular, the World Cancer Research Fund–American Institute for Cancer Research has recognized and promoted dietary fiber as a protective factor against colorectal cancer. However, most prospective studies on dietary fiber and GICs have been conducted in North America and Europe. Little is known about the association of dietary fiber with incident GIC among Koreans, [...]

A partir d'une revue systématique de la littérature publiée jusqu'en août 2022 (28 études), cette méta-analyse évalue l'association entre l'apport en vitamine B6, les taux sériques de phosphate de pyridoxal (PLP) et le risque de cancer colorectal

Association Between Vitamin B6 and the Risk of Colorectal Cancer: A Meta-analysis of Observational Studies

Lai, Jianxiong ; Guo, Mingqiao ; Wang, Dongmei ; Liu, Kuan ; Hu, Dengmin ; Li, Jian

Objective: This meta-analysis aimed to assess the association between vitamin B6 intake, blood PLP levels, and the risk of colorectal cancer. Methods: The databases PubMed, Cochrane Library and Embase databases were comprehensively searched for cohort studies or case-control studies. The odds ratio (OR) and 95% confidence interval (CI) were extracted from each eligible study, and the statistical software Stata was used to perform statistical merging. Results: Twenty-eight studies (20 cohort [...]

Menée en Floride sur la période 2018-2019 par enquête auprès de 272 professionnels de santé de structures de soins primaires, cette étude analyse leur stratégie de recommandation du vaccin contre le papillomavirus humain (HPV) et le respect des bonnes pratiques

North-Central Florida Clinicians' Human Papillomavirus Vaccine Recommendation Priorities and Practices for 11- to 12-Year-Olds: A Discrete Choice Experiment

Staras, Stephanie A. S. ; Salloum, Ramzi G. ; Osegueda, Eduardo ; Bylund, Carma L. ; Chi, Xiaofei ; Mohan, Vikasni ; Sage, Emily ; Huo, Tianyao ; Young, Alyson ; Thompson, Lindsay A.

Purpose: Within the United States, human papillomavirus (HPV) vaccination rates remain low. We examined HPV vaccine recommendation practices among Florida clinicians by assessing variability in: (1) recommendation priorities by patient characteristics and (2) concordance with best practices. Methods: In 2018 and 2019, we conducted a cross-sectional survey incorporating a discrete choice experiment among primary care clinicians (MD/DO, APRN, and PA). We used linear mixed-effects models to [...]

Menée aux Etats-Unis à partir de données d'une enquête réalisée sur la période 2011-2018 auprès de 5 567 adolescents (âge : 9-17 ans), cette étude compare le taux de première vaccination contre le papillomavirus humain (HPV) et le taux de schéma vaccinal complet, en fonction de l'origine ethnique

Lower human papillomavirus vaccine initiation and completion among Asian American adolescents compared to their peers: National Health and Nutritional Examination Survey 2011–2018

Zhao, Ran ; Prizment, Anna ; Kulasingam, Shalini

Purpose: To compare human papillomavirus (HPV) vaccination initiation and completion between Asian American adolescents and their peers. Methods: HPV vaccine initiation and completion of adolescents aged 9–17 years old were analyzed using the National Health and Nutritional Examination Survey data from 2011 to 2018. The outcomes were HPV vaccine initiation percentage among all adolescents and completion percentage among initiators. Odds ratios for initiation or completion among Hispanics, [...]

Menée en France par enquête téléphonique auprès de jeunes femmes âgées de 15 à 25 ans ou de leurs parents (2 426 participants au total), cette étude analyse leur attitude à l'égard de la vaccination contre le papillomavirus humain (HPV)

Vaccine hesitancy about the HPV vaccine among French young women and their parents: a telephone survey

Gauna, Fatima ; Verger, Pierre ; Fressard, Lisa ; Jardin, Marie ; Ward, Jeremy K. ; Peretti-Watel, Patrick

Background: The human papillomavirus (HPV) vaccine reduces the burden of cervical and other cancers. In numerous countries, a slow uptakeof this vaccine persists, calling for a better understanding of the structural factors leading to vaccine acceptation. We aimed to assess the attitudes toward HPV vaccination among its intended public to explore its specific characteristics. Methods: A random cross-sectional telephone survey of the French general population provided data from a sample of 2426 [...]

Menée par génotypage ADN de prélèvements vaginaux collectés auprès de 4 319 femmes éligibles à la vaccination contre le papillomavirus humain (HPV), cette étude analyse la prévalence de HPV et la charge virale 6 et 12 ans après la vaccination bivalente en fonction du nombre de doses prévues par le schéma vaccinal (2 ou 3)

Effects of two and three vaccinations with the bivalent HPV vaccine on the prevalence and load of HPV in clearing and persistent infections in young women

van Eer, Kahren ; Middeldorp, Marit ; Dzebisasjvili, Tsira ; Lamkaraf, Najima ; de Melker, Hester ; Steenbergen, Renske D M ; King, Audrey J

Human papillomavirus viral load (HPV VL) is associated with persistence, which increases cervical cancer risk. The bivalent vaccine protects against oncogenic HPV16/18 and cross-protects against several non-vaccine types. We examined the effect of two-dose (2D) and three-dose (3D) vaccination on HPV prevalence and viral load in clearing (CIs) and persistent infections (PIs), 6y and 12y post-vaccination, respectively.Vaginal swabs collected from HPV Among Vaccinated And Non-vaccinated [...]

Cette étude analyse les avantages et les inconvénients d'une gastrectomie totale pour prévenir un cancer gastrique diffus héréditaire

Unique challenges of risk-reducing surgery for hereditary diffuse gastric cancer syndrome: a narrative review

Gallanis, Amber F. ; Davis, Jeremy L.

The common use of genetic testing has reinvigorated discussions surrounding enhanced cancer surveillance, chemoprevention, and preventive surgery strategies due to increasing recognition of pathogenic germline genetic variants. Prophylactic surgery for hereditary cancer syndromes can significantly reduce the risk of developing cancer. Hereditary diffuse gastric cancer (HDGC), characterized by high penetrance and an autosomal dominant inheritance pattern, is causally linked to germline mutations [...]

Cette étude passe en revue les stratégies de prévention du carcinome épidermoïde oropharyngé lié au papillomavirus humain

How to prevent human papillomavirus-related oropharyngeal cancer?

Ferrando-Díez, Angelica ; Pavón, Miguel Angel ; Cirauqui, Beatriz ; Alemany, Laia ; Mesía, Ricard

Purpose of review: Human papillomavirus (HPV) is responsible of the increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in high-income countries. This significant epidemiological change requires several and diverse prevention strategies. Recent findings: The cervical cancer prevention model is the paradigm of HPV-related cancer, and its success provides encouragement for the development of similar methods to prevent HPV-related OPSCC. However, there are some limitations [...]