Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 560 du 7 avril 2023
Lutte contre les cancers
Qualité de vie, soins de support (2)
Menée en Australie à partir de données portant sur 150 patients ayant survécu à un cancer (âge moyen lors du diagnostic de cancer : 23,2 ans), cette étude analyse leurs difficultés sexuelles et leurs problèmes de fertilité
Sexual and reproductive complications and concerns of survivors of childhood, adolescent and adult cancer
Menée en Australie à partir de données portant sur 150 patients ayant survécu à un cancer (âge moyen lors du diagnostic de cancer : 23,2 ans), cette étude analyse leurs difficultés sexuelles et leurs problèmes de fertilité
Sexual and reproductive complications and concerns of survivors of childhood, adolescent and adult cancer
Gerstl, Brigitte ; Signorelli, Christina ; Wakefield, Claire E. ; Deans, Rebecca ; Vaishnav, Tejnei ; Johnston, Karen ; Neville, Kristen ; Cohn, Richard J. ; Anazodo, Antoinette
Purpose: Cancer survivors may experience infertility and sexual dysfunction following cancer treatment. Survivors report significant gaps in oncofertility care and consider these issues important, yet they are rarely discussed. The aims of this study were to evaluate survivors’ sexual and reproductive complications across age groups and to identify specific groups of survivors at risk for sexual and reproductive complications. Method: We report data collected from survivors of cancers diagnosed [...]
Mené sur 124 patients atteints d'un cancer gastrique de stade localement avancé ou métastatique, d'un cancer hépato-pancréatico-biliaire ou d'un cancer pulmonaire (âge médian : 55 ans), cet essai de phase II évalue l'intérêt de l'olanzapine pour prendre en charge une anorexie induite par la chimiothérapie
Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Ga...
Mené sur 124 patients atteints d'un cancer gastrique de stade localement avancé ou métastatique, d'un cancer hépato-pancréatico-biliaire ou d'un cancer pulmonaire (âge médian : 55 ans), cet essai de phase II évalue l'intérêt de l'olanzapine pour prendre en charge une anorexie induite par la chimiothérapie
Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Gastric, Hepatopancreaticobiliary, and Lung Cancer
Lakshmi Sandhya ; Nirmala Devi Sreenivasan ; Luxitaa Goenka ; Biswajit Dubashi ; Smita Kayal ; Manikandan Solaiappan ; Ramkumar Govindarajalou ; Harichandrakumar Kt ; Prasanth Ganesan
PURPOSE: Anorexia occurs in 30%-80% of patients with advanced malignancies, which may be worsened with chemotherapy. This trial assessed the efficacy of olanzapine in stimulating appetite and improving weight gain in patients receiving chemotherapy. METHODS: Adults (≥18 years) with untreated, locally advanced, or metastatic gastric, Randomized Double-Blind Placebo-Controlled Study of Olanzapine for Chemotherapy-Related Anorexia in Patients With Locally Advanced or Metastatic Gastric, [...]
Observation (9)
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The impact of the COVID-19 pandemic on perioperative chemotherapy for breast cancer
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The impact of the COVID-19 pandemic on perioperative chemotherapy for breast cancer
Baba, Kaede ; Kawamoto, Megumi ; Mamishin, Kanako ; Uematsu, Mao ; Kiyohara, Hikari ; Hirota, Akira ; Takahashi, Nobuyuki ; Fukuda, Misao ; Kusuhara, Shota ; Nakajima, Hiromichi ; Funasaka, Chikako ; Nakao, Takehiro ; Kondoh, Chihiro ; Harano, Kenichi ; Matsubara, Nobuaki ; Naito, Yoichi ; Hosono, Ako ; Kawasaki, Toshikatsu ; Mukohara, Toru
Background: Since it was first reported in December 2019, coronavirus disease 2019 (COVID-19) spread rapidly across the globe resulting in a pandemic. As of August 2022, seven outbreak peaks have been confirmed in Tokyo, and the numbers of new cases in the fifth and later outbreak periods have been far greater than in the preceding periods. This retrospective study examined the impact of the COVID-19 pandemic on perioperative chemotherapy for breast cancer. Methods: Patients with breast cancer [...]
Early survival for patients newly diagnosed with cancer during COVID-19 in Ontario, Canada: A population-based cohort study
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Early survival for patients newly diagnosed with cancer during COVID-19 in Ontario, Canada: A population-based cohort study
Fu, Rui ; Sutradhar, Rinku ; Li, Qing ; Kamalraj, Pabiththa ; Dare, Anna ; Hanna, Timothy P. ; Chan, Kelvin K. W. ; Irish, Jonathan C. ; Coburn, Natalie ; Hallet, Julie ; Singh, Simron ; Parmar, Ambica ; Earle, Craig C. ; Lapointe-Shaw, Lauren ; Krzyzanowska, Monika K. ; Louie, Alexander V. ; Mahar, Alyson ; Urbach, David R. ; McIsaac, Daniel I. ; Enepekides, Danny ; Gomez, David ; Look Hong, Nicole J. ; Tinmouth, Jill ; Eskander, Antoine
Background : Little is known about the association between the COVID-19 pandemic and early survival among newly diagnosed cancer patients. Methods: This retrospective population-based cohort study used linked administrative datasets from Ontario, Canada. Adults (≥18 years) who received a cancer diagnosis between March 15 and December 31, 2020, were included in a pandemic cohort, while those diagnosed during the same dates in 2018/2019 were included in a pre-pandemic cohort. All patients were [...]
Pandemic coping and COVID-19 preventive behaviors among cancer survivors
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Pandemic coping and COVID-19 preventive behaviors among cancer survivors
Guidry, Jeanine P. D. ; Miller, Carrie A. ; Perrin, Paul B. ; Carlyle, Kellie E. ; Savage, Matthew W. ; Sheppard, Vanessa B. ; Fuemmeler, Bernard F.
Background Cancer survivors are at greater risk for COVID-19 complications, emphasizing the importance of adherence to COVID-19 prevention. Active coping mechanisms can help manage pandemic stress but disengaged coping practices can have adverse effects. Objectives 1) Identify differences in COVID-19 coping styles and COVID-19 preventive behaviors among cancer survivors in active treatment, survivors not in treatment, and a comparison group without a cancer history. 2) Exploring variables that [...]
Cancer, more than a “COVID-19 co-morbidity”
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Cancer, more than a “COVID-19 co-morbidity”
Jani,Chinmay T. ; Schooley,Robert T. ; Mckay,Rana R. ; Lippman,Scott M.
Patients with cancer represent a particularly vulnerable population at risk of adverse outcomes related to COVID-19. Collectively, the initial studies, including patients with and without cancer, confirmed that patients with cancer had a higher risk of complications and death related to COVID-19. Subsequent studies on patients with COVID-19 and cancer investigated patient and disease-related factors associated with COVID-19 severity and morality. Multiple interconnected factors include [...]
The Impact of COVID-19 on Pediatric Malignancy Diagnosis and Treatment: Never the Same but Lessons Learned
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The Impact of COVID-19 on Pediatric Malignancy Diagnosis and Treatment: Never the Same but Lessons Learned
Katato, Ghadir K. ; Sitaula, Prasiksha ; Gupte, Avanti ; Al-Antary, Eman T.
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic affected the pediatric oncology population globally. Over the course of 2 years, increasing reports have been made to better understand this entity and its pathologic complications on these patients. The pandemic has allowed healthcare providers, hospital systems, and leading oncologic societies to quickly adapt and formulate new guidelines for the effective understanding, management, and treatment of patients with [...]
Impact of COVID-19 on hospital screening, diagnosis and treatment activities among prostate and colorectal cancer patients in Canada
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Impact of COVID-19 on hospital screening, diagnosis and treatment activities among prostate and colorectal cancer patients in Canada
Lee, Shin-Haw ; Ojo, Andrew Toye ; Halat, Matthew ; Bleibdrey, Nataly ; Zhang, Steven ; Chalmers, Rob ; Zimskind, Dan
Background: Suspension of cancer screening and treatment programs were instituted to preserve medical resources and protect vulnerable populations. This research aims to investigate the implications of COVID-19 on cancer management and clinical outcomes for patients with prostate and colorectal cancer in Canada. Methods: We examined hospital cancer screening, diagnosis, treatment, length of stay, and mortality data among prostate and colorectal cancer patients between April 2017 and March 2021. [...]
Prolonged SARS-CoV-2 Infection and Organizing Pneumonia in a Patient with Follicular Lymphoma, Treated with Obinutuzumab—Challenging Recognit...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Prolonged SARS-CoV-2 Infection and Organizing Pneumonia in a Patient with Follicular Lymphoma, Treated with Obinutuzumab—Challenging Recognition and Treatment
Łyżwa, E. ; Sobiecka, M. ; Lewandowska, K. ; Siemion-Szcześniak, I. ; Barańska, I. ; Klatt, M. ; Langfort, R. ; Szturmowicz, M. ; Tomkowski, W.
A Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causing coronavirus disease 2019 (COVID-19) led to a pandemic outbreak in 2019. COVID-19’s course and its treatment in immunocompromised patients are uncertain. Furthermore, there is a possibility of protracted SARS-CoV-2 infection and the need for repeated antiviral treatment. Monoclonal antibodies against CD20, which are used, among other things, in the therapy of chronic lymphocytic leukaemia and follicular lymphoma, can induct [...]
Correlates of smoking during COVID-19 in the LGBTQI + cancer survivor population
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Correlates of smoking during COVID-19 in the LGBTQI + cancer survivor population
Maglalang, Dale Dagar ; Lyerly, Reece ; Scout, N. F. N. ; Avila, Jaqueline C. ; Ahluwalia, Jasjit S.
Purpose: Stressors brought on by the pandemic may have further encouraged lesbian, gay, bisexual, transgender, queer, and intersex plus (LGBTQI +) cancer survivors to smoke. The purpose of this study is to examine factors associated with smoking among LGBTQI + cancer survivors during the pandemic. Methods: We used a secondary data analysis of OUT: The National Cancer Survey. We conducted logistic regression analysis to examine the associations between psychological distress, binge drinking, and [...]
Cancer stage and time from cancer diagnosis to first treatment during the COVID-19 pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Cancer stage and time from cancer diagnosis to first treatment during the COVID-19 pandemic
Mendonça e Silva, Diego Rodrigues ; Fernandes, Gisele Aparecida ; França e Silva, Ivan Leonardo Avelino ; Curado, Maria Paula
The 2019 coronavirus disease (COVID-19) pandemic has impacted cancer care and the diagnosis of new cases of cancer. We analyzed the impact of the COVID-19 pandemic on patients with cancer by comparing the number of newly diagnosed cases, cancer stage, and time to treatment in 2020 with those in 2018, 2019, and 2021. A retrospective cohort of all cancer cases treated at A.C. Camargo Cancer Center in 2018–2021, identified from the Hospital Cancer Registry, was studied. We analyzed single and [...]
Adverse Hematological Effects of COVID-19 Vaccination and Pathomechanisms of Low Acquired Immunity in Patients with Hematological Malignancies
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Adverse Hematological Effects of COVID-19 Vaccination and Pathomechanisms of Low Acquired Immunity in Patients with Hematological Malignancies
Yazdani, Armand N. ; DeMarco, Nathaniel ; Patel, Parth ; Abdi, Arian ; Velpuri, Prathosh ; Agrawal, Devendra K. ; Rai, Vikrant
The SARS-CoV-2 virus and the COVID-19 pandemic have spread across the world and severely impacted patients living with hematological conditions. Immunocompromised patients experience rapidly progressing symptoms following COVID-19 infection and are at high risk of death. In efforts to protect the vulnerable population, vaccination efforts have increased exponentially in the past 2 years. Although COVID-19 vaccination is safe and effective, mild to moderate side effects such as headache, [...]
Menée aux Etats-Unis à partir de données portant sur 87 patients atteints d'une polyarthrite rhumatoïde antérieure au diagnostic de cancer et sur 203 témoins, cette étude de cohorte rétrospective analyse l'association entre une utilisation d'inhibiteurs de points de contrôle immunitaire, la survenue d'événements indésirables et la mortalité
Mortality and immune-related adverse events after immune checkpoint inhibitor initiation for cancer among patients with pre-existing rheumatoid art...
Menée aux Etats-Unis à partir de données portant sur 87 patients atteints d'une polyarthrite rhumatoïde antérieure au diagnostic de cancer et sur 203 témoins, cette étude de cohorte rétrospective analyse l'association entre une utilisation d'inhibiteurs de points de contrôle immunitaire, la survenue d'événements indésirables et la mortalité
Mortality and immune-related adverse events after immune checkpoint inhibitor initiation for cancer among patients with pre-existing rheumatoid arthritis: a retrospective, comparative, cohort study
McCarter, Kaitlin R. ; Wolfgang, Taylor ; Arabelovic, Senada ; Wang, Xiaosong ; Yoshida, Kazuki ; Banasiak, Emily P. ; Qian, Grace ; Kowalski, Emily N. ; Vanni, Kathleen M. M. ; LeBoeuf, Nicole R. ; Buchbinder, Elizabeth I. ; Gedmintas, Lydia ; MacFarlane, Lindsey A. ; Rao, Deepak A. ; Shadick, Nancy A. ; Gravallese, Ellen M. ; Sparks, Jeffrey A.
Background: Patients with pre-existing rheumatoid arthritis initiating immune checkpoint inhibitors for cancer might be at risk of increased mortality, rheumatoid arthritis flares, and other immune-related adverse events (AEs). We aimed to determine whether pre-existing rheumatoid arthritis was associated with higher mortality and immune-related AE risk in patients treated with immune checkpoint inhibitors. Methods: This retrospective, comparative cohort study was conducted at the Mass General [...]
Reconciling immunotherapy and autoimmunity: not for the faint of heart
Menée aux Etats-Unis à partir de données portant sur 87 patients atteints d'une polyarthrite rhumatoïde antérieure au diagnostic de cancer et sur 203 témoins, cette étude de cohorte rétrospective analyse l'association entre une utilisation d'inhibiteurs de points de contrôle immunitaire, la survenue d'événements indésirables et la mortalité
Reconciling immunotherapy and autoimmunity: not for the faint of heart
Ye, Carrie
Immune checkpoint inhibitors, a class of immunotherapy, have revolutionised cancer therapy. Nearly half of all patients with metastatic cancer are eligible for immune checkpoint inhibitor treatment, and use for patients with early-stage cancers in the adjuvant setting is rapidly increasing. 1 Immune checkpoint inhibitors exert anti-tumour effects by blocking immune checkpoints, which typically downregulate T-cell responses and protect the body from inappropriate immune activation. Although [...]
Menée à partir de données du registre néerlandais des cancers portant sur près de 2 millions de patients atteints d'une tumeur solide diagnostiquée entre 1989 et 2018, cette étude analyse, en fonction du type de tumeur, l'évolution de la survie des patients présentant des métastases au diagnostic
Changes in survival in de novo metastatic cancer in an era of new medicines
Menée à partir de données du registre néerlandais des cancers portant sur près de 2 millions de patients atteints d'une tumeur solide diagnostiquée entre 1989 et 2018, cette étude analyse, en fonction du type de tumeur, l'évolution de la survie des patients présentant des métastases au diagnostic
Changes in survival in de novo metastatic cancer in an era of new medicines
Luyendijk, Marianne ; Visser, Otto ; Blommestein, Hedwig M ; de Hingh, Ignace H J T ; Hoebers, Frank J P ; Jager, Agnes ; Sonke, Gabe S ; de Vries, Elisabeth G E ; Uyl-de Groot, Carin A ; Siesling, Sabine
Background : Over the past decades, the therapeutic landscape has markedly changed for patients with metastatic solid cancer, yet few studies have evaluated its effect on population-based survival. The objective of this study was to evaluate the change in survival of patients with de novo metastatic solid cancers during the last 30 years. Methods : For this retrospective study, data from almost 2 million patients diagnosed with a solid cancer between January 1, 1989, and December 31, 2018, were [...]
Menée sur la période 2001-2016 auprès de 19 599 pompiers dont 10 786 ont travaillé au World Trade Center, cette étude analyse la mortalité globale et spécifique
All-cause and cause-specific mortality in a cohort of WTC-exposed and non-WTC-exposed firefighters
Menée sur la période 2001-2016 auprès de 19 599 pompiers dont 10 786 ont travaillé au World Trade Center, cette étude analyse la mortalité globale et spécifique
All-cause and cause-specific mortality in a cohort of WTC-exposed and non-WTC-exposed firefighters
Singh, Ankura ; Zeig-Owens, Rachel ; Cannon, Madeline ; Webber, Mayris P ; Goldfarb, David G ; Daniels, Robert D ; Prezant, David J ; Boffetta, Paolo ; Hall, Charles B
Objective: To compare mortality rates in World Trade Center (WTC)-exposed Fire Department of the City of New York (FDNY) firefighters with rates in similarly healthy, non-WTC-exposed/non-FDNY firefighters, and compare mortality in each firefighter cohort with the general population. Methods: 10 786 male WTC-exposed FDNY firefighters and 8813 male non-WTC-exposed firefighters from other urban fire departments who were employed on 11 September 2001 were included in the analyses. Only WTC-exposed [...]
Menée à partir de données 1992-2017 de 13 registres américains des cancers, cette étude analyse l'impact des inhibiteurs de tyrosine kinase sur l'évolution de la mortalité par sous-type de leucémie (leucémie myéloïde chronique, leucémie lymphoblastique aiguë, leucémie lymphoblastique chronique)
The Impact of Improved Treatments on Survival of Adult US Leukemia Patients: 1990 - 2018
Menée à partir de données 1992-2017 de 13 registres américains des cancers, cette étude analyse l'impact des inhibiteurs de tyrosine kinase sur l'évolution de la mortalité par sous-type de leucémie (leucémie myéloïde chronique, leucémie lymphoblastique aiguë, leucémie lymphoblastique chronique)
The Impact of Improved Treatments on Survival of Adult US Leukemia Patients: 1990 - 2018
Howlader, Nadia ; Sharon, Elad ; Bhattacharya, Manami ; Ehrlich, Lori A. ; Richardson, Nicholas C. ; Gormley, Nicole J. ; de Claro, R. Angelo ; Wood, Amy E. ; Mariotto, Angela B. ; Cronin, Kathleen A.
Introduction: Molecularly targeted therapies such as tyrosine kinase inhibitors (TKIs) are effective treatments for BCR-ABL-bearing leukemias. We evaluated the impact of TKIs on historical chronic myeloid leukemia (CML) mortality trends compared to acute lymphoblastic leukemia (ALL) and chronic lymphoblastic leukemia (CLL). Methods: Since mortality trends reflect combined effects of leukemia incidence and survival, we also evaluated the contribution of incidence and survival trends to mortality [...]
Mené entre 2017 et 2020 sur 251 patients atteints d'un cancer colorectal non métastatique et éligibles à la chirurgie (âge médian : 69 ans ; 55 % d'hommes), cet essai randomisé international évalue l'efficacité, du point de vue des complications postopératoires et de la récupération fonctionnelle, d'un programme de préhabilitation multimodale supervisé de 4 semaines (exercices physiques de haute intensité, intervention nutritionnelle, soutien psychologique et sevrage tabagique si nécessaire)
Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery:...
Mené entre 2017 et 2020 sur 251 patients atteints d'un cancer colorectal non métastatique et éligibles à la chirurgie (âge médian : 69 ans ; 55 % d'hommes), cet essai randomisé international évalue l'efficacité, du point de vue des complications postopératoires et de la récupération fonctionnelle, d'un programme de préhabilitation multimodale supervisé de 4 semaines (exercices physiques de haute intensité, intervention nutritionnelle, soutien psychologique et sevrage tabagique si nécessaire)
Effect of Multimodal Prehabilitation on Reducing Postoperative Complications and Enhancing Functional Capacity Following Colorectal Cancer Surgery: The PREHAB Randomized Clinical Trial
Molenaar, Charlotte Johanna Laura ; Minnella, Enrico Maria ; Coca-Martinez, Miquel ; ten Cate, David Wouter Gerard ; Regis, Marta ; Awasthi, Rashami ; Martínez-Palli, Graciela ; López-Baamonde, Manuel ; Sebio-Garcia, Raquel ; Feo, Carlo Vittorio ; van Rooijen, Stefanus Johannes ; Schreinemakers, Jennifer Marijke Janneke ; Bojesen, Rasmus Dahlin ; Gögenur, Ismail ; Van den Heuvel, Edwin R. ; Carli, Francesco ; Slooter, Gerrit Dirk ; PREHAB Study Group
Colorectal surgery is associated with substantial morbidity rates and a lowered functional capacity. Optimization of the patient’s condition in the weeks prior to surgery may attenuate these unfavorable sequelae.To determine whether multimodal prehabilitation before colorectal cancer surgery can reduce postoperative complications and enhance functional recovery.The PREHAB randomized clinical trial was an international, multicenter trial conducted in teaching hospitals with implemented enhanced [...]
Overcoming Implementation Challenges With Innovation and Patient Empowerment—Let’s Keep Moving With Prehabilitation
Mené entre 2017 et 2020 sur 251 patients atteints d'un cancer colorectal non métastatique et éligibles à la chirurgie (âge médian : 69 ans ; 55 % d'hommes), cet essai randomisé international évalue l'efficacité, du point de vue des complications postopératoires et de la récupération fonctionnelle, d'un programme de préhabilitation multimodale supervisé de 4 semaines (exercices physiques de haute intensité, intervention nutritionnelle, soutien psychologique et sevrage tabagique si nécessaire)
Overcoming Implementation Challenges With Innovation and Patient Empowerment—Let’s Keep Moving With Prehabilitation
Porter Starr, Kathryn N. ; Pavon, Juliessa M. ; Lagoo-Deenadayalan, Sandhya A.
Impaired functional capacity is associated with loss of independence, increased risk of readmission, or death after surgery. The current work by Molenaar et al is the largest randomized clinical trial on multimodal prehabilitation for colorectal cancer surgery to date and provides a robust evidence-based strategy for optimization before surgery. Both intention-to-treat and per-protocol analysis results showed that prehabilitation reduced postoperative complications. Faster and better functional [...]
Menée à partir de données portant sur 793 patientes atteintes d'un cancer du sein (durée médiane de suivi : 18,7 ans), cette étude analyse l'association entre une alimentation riche en graisses et la mortalité spécifique et toutes causes confondues (327 décès)
Dietary fats and all-cause and breast cancer specific mortality among women with breast cancer: The Western New York Exposures and Breast Cancer (W...
Menée à partir de données portant sur 793 patientes atteintes d'un cancer du sein (durée médiane de suivi : 18,7 ans), cette étude analyse l'association entre une alimentation riche en graisses et la mortalité spécifique et toutes causes confondues (327 décès)
Dietary fats and all-cause and breast cancer specific mortality among women with breast cancer: The Western New York Exposures and Breast Cancer (WEB) Study
Meyer, Danielle S. ; Millen, Amy E. ; Nie, Jing ; Trevisan, Maurizio ; Freudenheim, Jo L.
Background: Study results of pre-diagnostic dietary fat intake and breast cancer mortality have been inconclusive. While dietary fat subtypes (saturated (SFA), polyunsaturated (PUFA) and monounsaturated (MUFA) fatty acids) may have different biological effects, there is little evidence regarding the association of dietary fat and fat subtype intake with mortality after breast cancer diagnosis. Methods: Women with incident, pathologically confirmed invasive breast cancer and complete dietary [...]
Menée aux Etats-Unis à partir de données portant sur 107 207 patientes atteintes d'un cancer du sein et ayant reçu une chimiothérapie néoadjuvante, cette étude analyse le taux de réponse complète au traitement et la survie en fonction de l'origine ethnique
Response to Treatment, Racial and Ethnic Disparity, and Survival in Patients With Breast Cancer Undergoing Neoadjuvant Chemotherapy in the US
Menée aux Etats-Unis à partir de données portant sur 107 207 patientes atteintes d'un cancer du sein et ayant reçu une chimiothérapie néoadjuvante, cette étude analyse le taux de réponse complète au traitement et la survie en fonction de l'origine ethnique
Response to Treatment, Racial and Ethnic Disparity, and Survival in Patients With Breast Cancer Undergoing Neoadjuvant Chemotherapy in the US
Shubeck, Sarah ; Zhao, Fangyuan ; Howard, Frederick M. ; Olopade, Olufunmilayo I. ; Huo, Dezheng
With the increasing delivery of neoadjuvant chemotherapy (NACT) for patients with breast cancer in the US, it is important to know whether there is differential response to NACT by race and ethnicity and the potential long-term outcomes.To examine whether there were any racial and ethnic differences in pathologic complete response (pCR) rate following NACT and, if so, whether they varied by molecular subtype and were associated with survival.A retrospective cohort study was conducted including [...]
Menée à partir de données portant sur 105 patientes atteintes d'un cancer du sein de stade précoce et incluses dans un essai de phase II, cette étude rétrospective identifie les caractéristiques des patientes associées à la sévérité d'une neuropathie périphérique pendant la chimiothérapie par paclitaxel
Patient Characteristics Associated With Chemotherapy-Induced Peripheral Neuropathy Severity in a Phase II Clinical Trial: A Retrospective Analysis
Menée à partir de données portant sur 105 patientes atteintes d'un cancer du sein de stade précoce et incluses dans un essai de phase II, cette étude rétrospective identifie les caractéristiques des patientes associées à la sévérité d'une neuropathie périphérique pendant la chimiothérapie par paclitaxel
Patient Characteristics Associated With Chemotherapy-Induced Peripheral Neuropathy Severity in a Phase II Clinical Trial: A Retrospective Analysis
Zhi, Wanqing Iris ; Dreyfus, Nechama ; Lessing, Alexie ; Galantino, Marylou ; Piulson, Lauren ; Kot, Kevin Liu ; Li, Susan ; Bao, Ting
Introduction: Chemotherapy-induced peripheral neuropathy (CIPN) can lead to chemotherapy dose reduction, delay, and discontinuation, and has limited effective prevention strategies. Our study aimed to identify patient characteristics associated with CIPN severity during weekly paclitaxel chemotherapy in people with early-stage breast cancer. Methods: We retrospectively collected baseline data including participants’ age, gender, race, body mass index (BMI), hemoglobin (regular and A1C), thyroid [...]
Approches psycho-sociales (2)
Menée au Japon à partir de données portant sur 945 adolescents et jeunes adultes atteints d'un cancer (âge : 15-39 ans), cette étude rétrospective analyse les facteurs associés à leur utilisation des soins de santé psychique
Mental health care use and related factors in adolescents and young adults with cancer
Menée au Japon à partir de données portant sur 945 adolescents et jeunes adultes atteints d'un cancer (âge : 15-39 ans), cette étude rétrospective analyse les facteurs associés à leur utilisation des soins de santé psychique
Mental health care use and related factors in adolescents and young adults with cancer
Hirayama, Takatoshi ; Ikezawa, Satoru ; Okubo, Ryo ; Mizuta, Tomoko ; Iwata, Shintaro ; Suzuki, Tatsuya
Purpose: The actual state of mental health care use and related factors in adolescent and young adult (AYA) patients with cancer is not well understood in Japan. This study aimed to (1) examine the actual state of mental health care use among AYA patients with cancer and (2) describe socio-demographic and related factors associated with mental health care use. Methods: We retrospectively reviewed the medical records of AYA patients with cancer aged 15–39 who first visited the National Cancer [...]
Menée auprès de 126 patients atteints d'un cancer, cette étude transversale analyse la présence d'une fatigue, d'insomnies, de symptômes de dépression, d'anxiété et de stress après une greffe allogénique de cellules souches hématopoïétiques puis examine la relation entre ces symptômes
The level of fatigue, insomnia, depression, anxiety, stress, and the relationship between these symptoms following allogeneic hematopoietic stem ce...
Menée auprès de 126 patients atteints d'un cancer, cette étude transversale analyse la présence d'une fatigue, d'insomnies, de symptômes de dépression, d'anxiété et de stress après une greffe allogénique de cellules souches hématopoïétiques puis examine la relation entre ces symptômes
The level of fatigue, insomnia, depression, anxiety, stress, and the relationship between these symptoms following allogeneic hematopoietic stem cell transplantation: a cross-sectional study
Noyan, Sümeyye ; Gündogdu, Fatma ; Bozdağ, Sinem Civriz
Purpose: This study investigated the incidence of fatigue, insomnia, depression, anxiety, and stress symptoms in patients after allogeneic hematopoietic stem cell transplantation (AHSCT), as well as explored potential relationships among these symptoms. Methods: A total of 126 patients who had undergone transplantation at a university hospital at least one month prior to the study's commencement were included. The study was conducted as a cross-sectional and relational research, and data were [...]
Analyses économiques et systèmes de soins (1)
Menée aux Etats-Unis sur la période 1996-2016, cette étude présente une estimation de l'évolution des dépenses de santé pour le cancer du rein
Trends in health care spending on kidney cancer in the United States, 1996–2016
Menée aux Etats-Unis sur la période 1996-2016, cette étude présente une estimation de l'évolution des dépenses de santé pour le cancer du rein
Trends in health care spending on kidney cancer in the United States, 1996–2016
Takemura, Kosuke ; Ahmed, Newaz Shubidito ; Stukalin, Igor ; Gupta, Mehul ; Ma, Christopher ; Heng, Daniel Y. C.
Background: Paradigm shifts in kidney cancer management have led to higher health care spending. Here, total and per capita health care spending and primary drivers of change in health expenditures for kidney cancer in the United States between 1996 and 2016 are estimated. Methods: Public databases developed by the Institute for Health Metrics and Evaluation for the Disease Expenditure Project were used. The prevalence of kidney cancer was estimated from the Global Burden of Disease Study. [...]
Sensibilisation et communication (4)
A partir d'une revue des informations écrites émanant de sources réglementées et portant sur 29 médicaments anticancéreux ayant reçu une première autorisation de mise sur le marché par l'Agence européenne des médicaments (EMA) sur la période 2017-2019 (32 indications), cette étude évalue la fréquence à laquelle des informations pertinentes et précises sur les avantages et les incertitudes liées à ces médicaments sont communiquées aux patients et aux cliniciens
Communication of anticancer drug benefits and related uncertainties to patients and clinicians: document analysis of regulated information on presc...
A partir d'une revue des informations écrites émanant de sources réglementées et portant sur 29 médicaments anticancéreux ayant reçu une première autorisation de mise sur le marché par l'Agence européenne des médicaments (EMA) sur la période 2017-2019 (32 indications), cette étude évalue la fréquence à laquelle des informations pertinentes et précises sur les avantages et les incertitudes liées à ces médicaments sont communiquées aux patients et aux cliniciens
Communication of anticancer drug benefits and related uncertainties to patients and clinicians: document analysis of regulated information on prescription drugs in Europe
Davis, Courtney ; Wagner, Anita K ; Salcher-Konrad, Maximilian ; Scowcroft, Henry ; Mintzes, Barbara ; Pokorny, Adrian M J ; Lew, Jianhui ; Naci, Huseyin
Objective: To evaluate the frequency with which relevant and accurate information about the benefits and related uncertainties of anticancer drugs are communicated to patients and clinicians in regulated information sources in Europe. Design: Document content analysis. Setting: European Medicines Agency. Participants: Anticancer drugs granted a first marketing authorisation by the European Medicines Agency, 2017-19. Main outcome measures: Whether written information on a product addressed [...]
Communicating the benefits and harms of anticancer drugs
A partir d'une revue des informations écrites émanant de sources réglementées et portant sur 29 médicaments anticancéreux ayant reçu une première autorisation de mise sur le marché par l'Agence européenne des médicaments (EMA) sur la période 2017-2019 (32 indications), cette étude évalue la fréquence à laquelle des informations pertinentes et précises sur les avantages et les incertitudes liées à ces médicaments sont communiquées aux patients et aux cliniciens
Communicating the benefits and harms of anticancer drugs
Feeney, Timothy ; Villanueva, Tiago ; Price, Amy
Informed consent is a central tenet of ethical clinical practice and shared decision making, and it requires that patients have easy access to independent and comprehensive information about medicines. For instance, is accurate information about benefits and harms available, is it complete, and is it presented in ways that ensure patients understand the benefits and harms from key research findings and the extent of remaining uncertainties? In a linked paper, Davis and colleagues [...]
A partir d'une revue systématique de la littérature (15 études incluant 374 patients et 471 professionnels de santé), cette étude analyse les expériences des patients atteints d'un cancer et des professionnels de santé vis-à-vis des conseils nutritionnels reçus ou prodigués
Experiences of cancer patients in receiving dietary advice from healthcare professionals and of healthcare professionals in providing this advice—a...
A partir d'une revue systématique de la littérature (15 études incluant 374 patients et 471 professionnels de santé), cette étude analyse les expériences des patients atteints d'un cancer et des professionnels de santé vis-à-vis des conseils nutritionnels reçus ou prodigués
Experiences of cancer patients in receiving dietary advice from healthcare professionals and of healthcare professionals in providing this advice—a systematic review
Keaver, Laura ; O’Callaghan, Niamh ; LaVertu, Amy E. ; Semple, Cherith J. ; Hughes, Ciara M. ; Hanna, Jeffrey R. ; Ryan, Lisa
Purpose: This systematic review investigated qualitative and quantitative studies exploring patients and healthcare professionals’ (HCP) experience of nutrition care throughout the cancer journey. Methods: Five databases were systematically searched for studies reporting on patient and healthcare professionals’ experience of nutrition advice. Results: Fifteen studies including 374 patients and 471 healthcare professionals were included. Findings indicate that patients desire more specific [...]
Menée en Irlande à l'aide des données d'une enquête réalisée auprès de 7 498 personnes de plus de 15 ans, cette étude identifie les facteurs associés à une connaissance du risque de cancer du sein lié à une consommation d'alcool
Factors associated with public awareness of the relationship between alcohol use and breast cancer risk
Menée en Irlande à l'aide des données d'une enquête réalisée auprès de 7 498 personnes de plus de 15 ans, cette étude identifie les facteurs associés à une connaissance du risque de cancer du sein lié à une consommation d'alcool
Factors associated with public awareness of the relationship between alcohol use and breast cancer risk
Doyle, Anne ; O’Dwyer, Claire ; Mongan, Deirdre ; Millar, Seán R. ; Galvin, Brian
Background: Public awareness of the carcinogenic effects of alcohol is low, particularly the association between alcohol use and the risk of developing breast cancer. Breast cancer is the third most common cancer in Ireland and alcohol use remains high. This study examined factors related to awareness of the association between alcohol use and breast cancer risk. Methods: Using data from Wave 2 of the national Healthy Ireland Survey, a representative sample of 7,498 Irish adults aged [...]
Menée à partir de données de 3 enquêtes réalisées entre 2017 et 2019 auprès de millions de femmes américaines, cette étude analyse leur connaissance du dépistage du papillomavirus humain (HPV)
Lack of awareness of human papillomavirus testing among U.S. women
Menée à partir de données de 3 enquêtes réalisées entre 2017 et 2019 auprès de millions de femmes américaines, cette étude analyse leur connaissance du dépistage du papillomavirus humain (HPV)
Lack of awareness of human papillomavirus testing among U.S. women
Berkowitz, Zahava ; Qin, Jin ; Smith, Judith Lee ; Saraiya, Mona
Introduction: National surveys provide important information for public health planning. Lack of preventive screenings awareness may result in unreliable survey estimates. This study examines women's awareness of receiving human papillomavirus (HPV) testing using three national surveys. Methods: In 2022, self-reported data analyses on HPV testing status among women without hysterectomy were conducted from the 2020 Behavioral Risk Factor Surveillance System [BRFSS, n=80648, (aged 30-64 years)], [...]
