How to prevent human papillomavirus-related oropharyngeal cancer?

Cette étude passe en revue les stratégies de prévention du carcinome épidermoïde oropharyngé lié au papillomavirus humain

Current Opinion in Oncology, sous presse, 2023, résumé

Résumé en anglais

Purpose of review: Human papillomavirus (HPV) is responsible of the increasing incidence rates of oropharyngeal squamous cell carcinoma (OPSCC) in high-income countries. This significant epidemiological change requires several and diverse prevention strategies.

Recent findings: The cervical cancer prevention model is the paradigm of HPV-related cancer, and its success provides encouragement for the development of similar methods to prevent HPV-related OPSCC. However, there are some limitations that hinder its application in this disease. Here, we review the primary, secondary and tertiary prevention of HPV-related OPSCC and discuss some directions for future research.

Summary: The development of new and targeted strategies to prevent HPV-related OPSCC is needed since they could definitely have a direct impact on the reduction of morbidity and mortality of this disease.