Menée en France à partir de données hospitalières portant sur 1,2 millions de témoins et 160 129 patients ayant eu recours à une chirurgie bariatrique (âge : 18-50 ans ; durée de suivi : 5,2 ans), cette étude analyse l'effet de la chirurgie sur le risque de cancer du pancréas lié à l'obésité

Bariatric surgery reduces the risk of pancreatic cancer in individuals with obesity before the age of 50 years: A nationwide administrative data study in France

Bulsei, Julie ; Chierici, Andrea ; Alifano, Marco ; Castaldi, Antonio ; Drai, Céline ; De Fatico, Serena ; Rosso, Edoardo ; Fontas, Eric ; Iannelli, Antonio

Background: Obesity is a well-established risk factor for pancreatic cancer. Bariatric surgery has demonstrated superior results in terms of weight loss and obesity-related comorbidities compared to medical and behavioral treatments. The aim of this study is to evaluate the effect of bariatric surgery on pancreatic cancer incidence in individuals with obesity. Method: Individuals with a diagnosis of obesity were retrieved from the French national hospital discharge database. We conducted a [...]

Menée à l'aide d'une modélisation et à partir des données d'une enquête réalisée en 2015, cette étude évalue la part évitable des cancers de l'estomac liée à la mise en place d'une politique de réduction de la consommation de sel au Vietnam

Avoidable burden of stomach cancer and potential gains in healthy life years from gradual reductions in salt consumption in Vietnam, 2019–2030: a modelling study

Aminde, Leopold Ndemnge ; Cobiac, Linda J. ; Phung, Dung ; Phung, Hai N. ; Veerman, J. Lennert

Objective: Excess salt consumption is causally linked with stomach cancer, and salt intake among adults in Vietnam is about twice the recommended levels. The aim of this study was to quantify the future burden of stomach cancer that could be avoided from population-wide salt reduction in Vietnam. Design: A dynamic simulation model was developed to quantify the impacts of achieving the 2018 National Vietnam Health Program (8 g/d by 2025 and 7 g/d by 2030) and the WHO (5 g/d) salt reduction [...]

Menée à partir des données de la "Melbourne Collaborative Cohort Study" portant sur 33 690 personnes (durée moyenne de suivi : 23,7 ans), cette étude analyse l'association entre la qualité et le potentiel inflammatoire de l'alimentation et le risque de cancer du pancréas (258 cas)

Dietary Inflammatory Index, Alternative Healthy Eating Index-2010, Mediterranean Diet Score and the risk of pancreatic cancer

Afshar, Nina ; Hodge, Allison M. ; Shivappa, Nitin ; Hebert, James R. ; Giles, Graham G. ; English, Dallas R. ; Milne, Roger L.

Background: Previous studies of dietary patterns and pancreatic cancer risk have been inconclusive; we aimed to investigate the association of Mediterranean Diet Score (MDS), Alternative Healthy Eating Index-2010 (AHEI-2010), and Dietary Inflammatory Index (DII®) with risk of pancreatic cancer. Methods: We used data from the Melbourne Collaborative Cohort Study including 33,690 men and women aged 40–69 years at recruitment in 1990–1994. A total of 258 incident cases of pancreatic cancer was [...]

Menée à partir de données 2001-2018 de registres danois portant sur 68 852 patientes atteintes d'un cancer du sein (âge médian : 62 ans), cette étude analyse l'association entre une utilisation de médicaments antiplaquettaires et le risque de développer la maladie

Antiplatelet drugs and breast cancer risk in a large nationwide Danish case-control study

Cairat, Manon ; Pottegård, Anton ; Olesen, Morten ; Dossus, Laure ; Fournier, Agnès ; Hicks, Blanaid

Low-dose aspirin has been hypothesized to prevent cancer risk by inhibiting platelet aggregation. However, the anti-cancer effect of low-dose aspirin has recently been questioned and its effect on breast cancer development remains unclear. The impact of other antiplatelet drugs on breast cancer risk has rarely been evaluated. Thus, this study aimed to investigate the associations between breast cancer risk and antiplatelet drug use in a nationwide nested case-control study. From the Danish [...]

Cette étude analyse l'effet de l'interdiction de fumer à l'intérieur des lieux de travail ou des lieux publics au Danemark sur l'incidence de 8 maladies liées au tabac

The impact of the Danish national smoking ban from 2007 on the incidence of eight smoking-related diseases – a nationwide register-based interrupted time series analysis

Jarlstrup, Nanna Schneekloth ; Thygesen, Lau Caspar ; Grønbæk, Morten Klöcker ; Rod, Morten Hulvej ; Tolstrup, Janne Schurmann

Previous research has documented the effect of comprehensive smoking bans on preventing various adverse health outcomes in the years post-ban. In 2007, Denmark implemented a national smoking ban that prohibited indoor smoking in workplaces and public settings, although only partial restrictions applied in specific premises such as small bars, one-person offices, and in psychiatric units. We tested the hypothesis that the implementation of the national smoking ban was associated with a decrease [...]

Menée à New York entre 2017 et 2020 sur 320 fumeurs quotidiens adultes, cet essai randomisé évalue l'intérêt, du point de vue de l'abstinence tabagique, d'un allongement de la durée d'utilisation de la varénicline (4 semaines au lieu d'1)

Effect of Extending the Duration of Prequit Treatment With Varenicline on Smoking Abstinence: A Randomized Clinical Trial

Hawk, Larry W., Jr ; Tiffany, Stephen T. ; Colder, Craig R. ; Ashare, Rebecca L. ; Wray, Jennifer M. ; Tyndale, Rachel F. ; Brandon, Thomas H. ; Mahoney, Martin C.

Even with varenicline, the leading monotherapy for tobacco dependence, smoking abstinence rates remain low. Preliminary evidence suggests that extending the duration of varenicline treatment before quitting may increase abstinence.To test the hypotheses that, compared with standard run-in varenicline treatment (1 week before quitting), extended run-in varenicline treatment (4 weeks before quitting) reduces smoking exposure before the target quit date (TQD) and enhances abstinence, particularly [...]

A partir d'une revue systématique de la littérature publiée entre 2000 et 2021 (34 articles), cette étude évalue l'efficacité d'une orientation des fumeurs, par les professionnels de santé, vers des thérapies cognitivo-comportementales pour le sevrage tabagique

Proactive referral to behavioral smoking cessation programs by healthcare staff: a systematic review

Willemsen, Marc C ; van Westen-Lagerweij, Naomi A ; Hipple Walters, Bethany J ; Potyka, Franziska ; Croes, Esther A

Behavioral smoking cessation programs are an effective tool for quitting smoking, yet remain underused by smokers. Proactive referral may be a promising strategy for healthcare staff to connect smokers to such programs. The aim of this study was to gain insight into the effectiveness and implementability of proactive referral of smokers to behavioral smoking cessation programs by healthcare staff.A systematic review was conducted using five databases. Effectiveness of proactive referral was [...]