Menée auprès de 279 patients ayant survécu à un cancer, cette étude évalue la faisabilité d'un programme de réadaptation en ligne pour les patients éprouvant des troubles cognitifs au travail

Internet-based cognitive rehabilitation for working cancer survivors: A process evaluation

Klaver, Kete M. ; Duijts, Saskia F.A. ; Geusgens, Chantal A.V. ; Aarts, Maureen J.B. ; Ponds, Rudolf W.H.M. ; van der Beek, Allard J. ; Schagen, Sanne B.

Objective: To evaluate the process of an online cognitive rehabilitation program aimed at supporting cancer survivors experiencing cognitive problems at work. Methods: Cancer survivors (n = 279) were randomized to one of the intervention groups (i.e., basic and extensive online cognitive rehabilitation) or waitlist control group. Recruitment, reach, dosage, implementation, perceived usefulness and experiences with the program were evaluated using questionnaires and logbooks. Results: [...]

Menée par questionnaire électronique auprès de 9 350 patients atteints d'un cancer en cours de traitement, cette étude estime la prévalence de symptômes d'insomnie déclarés par les patients puis analyse les facteurs associés à ce trouble du sommeil

Insomnia Prevalence and Correlates in Cancer Patients Undergoing Treatment

Page, Jessica M. ; Morgans, Alicia K. ; Hassett, Michael J. ; Haakenstad, Ellana ; Manni, Michael ; McCleary, Nadine J. ; Zhou, Eric S.

Background: Insomnia is the most common sleep disturbance among cancer patients undergoing active treatment. If untreated, it is associated with significant physical and psychological health consequences. Prior efforts to determine insomnia prevalence and correlates have primarily assessed patients in clinical trials, in limited disease groups, and excluding important patient subgroups. These findings are likely to be influenced by research participation effects, which could bias outcomes. We [...]

Menée auprès de 143 patients atteints d'un lymphome non hodgkinien récemment diagnostiqué (âge médian : 50,2 ans ; durée médiane de suivi : 18,8 mois), cette étude multicentrique évalue l'influence de l'état nutritionel sur la toxicité de la chimiothérapie et la survie

The dynamic effects of nutritional status on chemotherapy-related toxicity in patients with non-Hodgkin’s lymphoma

Zhou, Qian ; Yang, HeXiang ; Wang, Xinyue ; Wang, LiHong ; Yan, XueQian ; Zhang, BeiRong ; Ma, XueHong ; Li, GuoHua ; Li, JingLin ; Zhang, JiaHui ; Yan, ZhiHong ; Bao, Ni ; Li, Chao ; Ge, Peng ; Liu, Jia ; Luo, Xiaoqin

Background/Objectives: Understanding the dynamic changes in nutritional status of patients with non-Hodgkin’s lymphoma (NHL) during chemotherapy is crucial, as it significantly impacts chemotherapy-related toxicity and survival outcomes. Subjects/Methods: This multi-center study included newly diagnosed NHL patients. Nutritional status and chemotherapy-related toxic effects were assessed over the first five chemotherapy sessions, with follow-ups conducted every 3 months. Patients were [...]

Menée à l'aide de données néerlandaises portant sur 3 877 témoins et 133 adolescents ou jeunes adultes ayant survécu à une tumeur cérébrale, cette étude analyse la prévalence de séquelles physiques et psychologiques ainsi que la qualité de vie liée à la santé

Adverse health outcomes and health-related quality of life (HRQoL) among long-term adolescent and young adult (AYA) brain tumour survivors: results from the population-based SURVAYA study

Angoumis, Konstantinos ; Padilla, Catarina S. ; Kouwenhoven, Mathilde C. M. ; Bijlsma, Rhodé M. ; Kaal, Suzanne E. J. ; Tromp, Jacqueline M. ; Bos, Monique E. M. M. ; van der Hulle, Tom ; Broen, Martinus P. G. ; Nuver, Janine ; van der Graaf, Winette T. A. ; Pauge, Sophie ; Husson, Olga

Purpose: Adolescent and young adult (AYA) malignant brain tumour (BT) survivors are at risk of adverse health outcomes, which may impact their health-related quality of life (HRQoL). This study aimed to investigate the (1) prevalence of physical and psychological adverse health outcomes, (2) the HRQoL, and (3) the association of adverse health outcomes and HRQoL among long-term AYA-BT survivors. Adverse health outcomes and HRQoL were compared to other AYA cancer (AYAC) survivors. Methods: A [...]

Cette étude fait le point sur l'incidence des tumeurs neuroendocrines gastro-entéro-pancréatiques aux Etats-Unis par âge et sexe

Gastroenteropancreatic Neuroendocrine Tumor Incidence by Sex and Age in the US

Abboud, Yazan ; Shah, Anand ; Sutariya, Riya ; Shah, Vraj P. ; Al-Khazraji, Ahmed ; Gaglio, Paul J. ; Hajifathalian, Kaveh

Neuroendocrine tumors (NETs) are indolent neoplasms arising from cells of the neuroendocrine system, most frequently in the gastrointestinal tract. A prior analysis showed increasing incidence of gastroenteropancreatic NETs (GEP-NETs) in the US, with variations among organs and with higher rates in older patients and males. However, we lack nationwide representative data assessing GEP-NETs among different demographic groups and organ types. Given the variation of manifestations, management, and [...]

Menée à partir de données mondiales 1990-2021 de la base "Global Burden of Disease", cette étude analyse l'évolution de l'incidence des cancers féminins (sein, col de l'utérus, ovaire, endomètre), la mortalité et les années de vie ajustées sur l'incapacité ainsi que les facteurs de risque associés

Global status and attributable risk factors of breast, cervical, ovarian, and uterine cancers from 1990 to 2021

Li, Tianye ; Zhang, Haoxiang ; Lian, Mengyi ; He, Qionghua ; Lv, Mingwei ; Zhai, Lingyun ; Zhou, Jianwei ; Wu, Kongming ; Yi, Ming

Background: Female-specific cancers, particularly breast, cervical, ovarian, and uterine cancers, account for nearly 40% of all cancers in women. This study aimed to analyze the global epidemiological trends of these cancers from 1990 to 2021, offering insights into their evolving patterns and providing valuable information for health policymakers to allocate healthcare resources more effectively. Methods: Data from the Global Burden of Disease Study 2021 (GBD 2021) were used to comprehensively [...]

Menée à partir de données de 284 registres internationaux des cancers portant sur 1,5 million d'adultes atteints d'un mélanome cutané, cette étude analyse la survie nette à 5 ans en fonction de l'âge au diagnostic et du sexe

Sex differences in survival from melanoma of the skin: the role of age, anatomic location and stage at diagnosis: a CONCORD-3 study in 59 countries

Di Carlo, V. ; Eberle, A. ; Stiller, C. ; Bennett, D. ; Katalinic, A. ; Gragera, R. Marcos ; Girardi, F. ; Larønningen, S. ; Schultz, A. ; Lima, C. A. ; Coleman, M. P. ; Allemani, C.

Background: CONCORD-3 highlighted wide disparities in population-based 5-year net survival for cutaneous melanoma during 2000-2014. Studies showed a survival advantage in women, but the reasons are not completely understood. We aim to estimate trends in age-standardised 5-year net survival by sex and to examine the role of age, anatomic location and stage on the survival advantage for women worldwide. Methods: Patients were grouped into five anatomic locations (head and neck, trunk, limbs, [...]

Menée à l'aide de données internationales portant sur 1 753 patients atteints d'un mélanome cutané (durée de suivi : 7,4 ans), cette étude analyse la survie en fonction de caractéristiques clinicopathologiques et du sexe

Sex Differences in Melanoma Survival—a GEM study

Murali, Tharani ; Schwartz, Matthew ; Reynolds, Adam Z ; Luo, Li ; Ridgeway, Grace ; Busam, Klaus J ; Cust, Anne E ; Anton-Culver, Hoda ; Gallagher, Richard P ; Zanetti, Roberto ; Rosso, Stefano ; Sacchetto, Lidia ; Begg, Colin B ; Orlow, Irene ; Thomas, Nancy E ; Berwick, Marianne ; for the GEM Study Team

Sex differences in melanoma are prominent, with females having a significant survival advantage. However, it is unclear why we see this survival advantage. Here we investigate the relationship between sex, clinicopathologic variables, and melanoma specific survival in 1,753 single primary melanomas from patients in the GEM study. Using Cox proportional hazard models and formal mediation analysis, the effect of sex on survival is explained largely by differences in the clinicopathologic features [...]

Menée à l'aide de données de la base "EUROCARE-6", cette étude analyse l'incidence des sarcomes et la survie associée par sous-type et par tranche d'âges (adolescents ou jeunes adultes, enfants, adultes, adultes matures)

Incidence and survival of European adolescents and young adults diagnosed with sarcomas: EUROCARE-6 results

Trama, Annalisa ; Lasalvia, Paolo ; Stark, Dan ; McCabe, Martin G. ; Graaf, Winette van der ; Gaspar, Nathalie ; Metayer, Lucy ; Strauss, Sandra J. ; Ragusa, Rosalia ; Guevara, Marcela ; Bennett, Damien ; Dal Maso, Luigino ; Batllés, Ana María Vizcaíno ; Schindera, Christina ; Mousavi, Seyed Mohsen ; Cerza, Francesco ; Botta, Laura ; Ferrari, Andrea ; Provenzano, Salvatore

Background: Epidemiological data for sarcoma in adolescents and young adults (AYAs) and across age groups are limited. We aim to: 1) update sarcoma incidence, survival, and changes over time in European AYAs 2) provide an updated comparison of sarcoma survival in AYAs versus children and mature adults. Methods: We calculated crude incidence rates (IR) per 100,000 European population per year from 2006 to 2013. Using the period approach, we calculated 5-year relative survival (RS) for the [...]

Menée à partir de données 1970-1999 de l'étude "Childhood Cancer Survivor Study" portant sur des patients ayant survécu à un cancer pédiatrique, cette étude analyse l'incidence des tumeurs cérébrales secondaires en fonction de la période de diagnostic du premier cancer (1970-1979, 1980-1989 ou 1990-1999)

Temporal Trends of Subsequent CNS Malignancies Among Survivors of Childhood Cancer

Galvin, Robert T ; Chen, Yan ; Yuan, Yan ; Cooney, Tabitha ; Howell, Rebecca ; Smith, Susan ; Arnold, Michael A ; Conces, Miriam ; Leisenring, Wendy ; Armstrong, Gregory T ; Neglia, Joseph P ; Turcotte, Lucie M

It is not known whether temporal changes in childhood cancer therapy have reduced risk of subsequent malignant neoplasms (SMNs) of the central nervous system (CNS), a frequently fatal late effect of cancer therapy.Five-year survivors of primary childhood cancers diagnosed between 1970-1999 in the Childhood Cancer Survivor Study with a subsequent CNS SMN were identified. Cumulative incidence rates and standardized incidence ratios (SIR) were compared among survivors diagnosed between 1970-1979 [...]

Menée à l'aide de données 1980-2019 du registre biélorusse des cancers, cette étude analyse l'évolution de l'incidence du cancer papillaire de la thyroïde liée aux rejets d'iode 131 après Tchernobyl, par âge

The incidence trends of papillary thyroid carcinoma in Belarus during the post-Chernobyl epoch

Fridman, Mikhail ; Krasko, Olga ; Veyalkin, Ilya

Background: The increase of papillary thyroid cancer (PTC) rate among children who were exposed to post-Chernobyl 131-I release was reported only four years after the accident, first in Belarus where the heaviest fallout happened. The evolution of the occurrence of thyroid carcinoma based on the age-period-cohort analysis and the effects of age, period, and birth cohort on time trends aimed to reveal if post-Chernobyl follicular cells irradiation still has been impacting on incidence rate of [...]

Cette étude analyse les facteurs favorisant un trouble de l'image corporelle chez les patients ayant subi une chirurgie pour un cancer de la cavité buccale

Exploration of Body Image in Postoperative Patients With Oral Cancer: An Exploratory Sequential Mixed Methods Study

Wang, Xiaohui ; Lin, Chunni ; Zhou, Jiajing ; Cao, Yanyi ; Chen, Yiqiong ; Hu, Xiang ; Qiu, Jie ; Cong, Li

Background: Postoperative patients with oral cancer are deeply distressed about their body image. However, their true inner feelings and the factors influencing body image remain unclear. Aims: This study aims to investigate the experience of body image disturbance in patients 3 months after oral cancer surgery and analyze the influencing factors. Methods: This study process was divided into three steps: (1) semi-structured interviews, based on the Society Ecosystems Theory, of patients with [...]

A partir d'une revue systématique de la littérature publiée jusqu'en juillet 2024 (11 études, 1 654 patients), cette méta-analyse évalue l'effet d'interventions menées par des professionnels de santé sur l'observance thérapeutique des patients atteints d'un cancer et recevant une thérapie ciblée par voie orale

The effect of healthcare professional-implemented interventions on adherence to oral targeted therapy in patients with cancer: a systematic review and meta-analysis

Angus, Fiona ; Liao, Wan-Chuen ; Adekoya, Victoria ; Chen, Li-Chia

Purpose: This study investigated the impact of healthcare professional-led interventions on adherence to oral targeted therapy and identified the behavior change techniques (BCTs) underpinning the interventions. Methods: A systematic search of MEDLINE, Embase, APA PsycInfo, CINAHL Plus, PubMed, and Web of Science up to July 2024 identified randomized controlled trials and cohort studies involving adult patients (≥ 18 years) with cancer on oral targeted therapy receiving healthcare [...]