Menée à l'aide de données américaines collectées sur la période 2014-2021 auprès de 1 985 adultes fumant quotidiennement (âge moyen : 40 ans), cette étude analyse l'association entre des caractéristiques d'utilisation de la cigarette électronique (fréquence d'utilisation, type d'arôme, type de dispositif) et un comportement de sevrage tabagique

E-Cigarette Characteristics and Cigarette Cessation Among Adults Who Use E-Cigarettes

Kasza, Karin A. ; Rivard, Cheryl ; Goniewicz, Maciej L. ; Fong, Geoffrey T. ; Hammond, David ; Cummings, K. Michael ; Hyland, Andrew

Population-level health outcomes associated with e-cigarettes depend in part on the association between e-cigarettes and combustible cigarette cessation. The US Food and Drug Administration has authority to regulate e-cigarette characteristics, including flavor and device type.To investigate whether e-cigarette characteristics are associated with cigarette cessation behaviors among adults in the US population who use e-cigarettes.This cohort study was conducted using longitudinal data collected [...]

Mené en Chine sur 180 284 personnes ayant effectué un test respiratoire à l'urée marquée (durée de suivi : 11,8 ans), cet essai randomisé évalue la supériorité, du point de vue de l'incidence du cancer de l'estomac chez les personnes testées positives, d'une quadrithérapie d'éradication d'Helicobacter pylori pendant 10 jours (oméprazole, tétracycline, métronidazole et citrate de bismuth) par rapport à un traitement quotidien pour atténuer les symptômes (oméprazole et citrate de bismuth)

Gastric cancer prevention by community eradication of Helicobacter pylori: a cluster-randomized controlled trial

Pan, Kai-Feng ; Li, Wen-Qing ; Zhang, Lian ; Liu, Wei-Dong ; Ma, Jun-Ling ; Zhang, Yang ; Ulm, Kurt ; Wang, Jian-xi ; Zhang, Lei ; Bajbouj, Monther ; Zhang, Lan-fu ; Li, Ming ; Vieth, Michael ; Quante, Michael ; Wang, Le-hua ; Suchanek, Stepan ; Mejias-Luque, Raquel ; Xu, Heng-Min ; Fan, Xiao-Han ; Han, Xuan ; Liu, Zong-Chao ; Zhou, Tong ; Guan, Wei-xiang ; Schmid, Roland M. ; Gerhard, Markus ; Classen, Meinhard ; You, Wei-Cheng

Gastric cancer is a leading cause of cancer-related deaths in China. Affecting more than 40% of the world’s population, Helicobacter pylori is a major risk factor for gastric cancer. While previous clinical trials indicated that eradication of H. pylori could reduce gastric cancer risk, this remains to be shown using a population-based approach. We conducted a community-based, cluster-randomized, controlled, superiority intervention trial in Linqu County, China, with individuals who tested [...]

Menée à partir de données portant sur 14 876 témoins et 3 719 patients atteints d'un cancer du foie, cette étude analyse l'association entre une utilisation de médicaments hypocholestérolémiants (autres que les statines) et le risque de développer la maladie

Use of cholesterol-lowering medications in relation to risk of primary liver cancer in the Clinical Practice Research Datalink

Zamani, Shahriar A. ; Graubard, Barry I. ; Hyer, Marianne ; Carver, Emily ; Petrick, Jessica L. ; McGlynn, Katherine A.

Background: Although the relation between statin use and liver cancer risk has been extensively examined, few studies have examined other cholesterol-lowering medications in relation to liver cancer risk. The authors examined five classes of nonstatin medications and liver cancer risk. Methods: A nested case–control including 3719 cases and 14,876 matched controls was conducted within the Clinical Practice Research Datalink. Additional matches on type 2 diabetes and chronic liver disease were [...]

Menée à partir de données des cohortes américaines "the Nurses’ Health Study" et "the Health Professionals Follow-Up Study" portant sur 107 655 personnes, cette étude analyse l'effet de la qualité du mode de vie, évaluée à l'aide d'un système de score, sur l'association entre une utilisation d'aspirine et le risque de cancer colorectal

Aspirin Use and Incidence of Colorectal Cancer According to Lifestyle Risk

Sikavi, Daniel R. ; Wang, Kai ; Ma, Wenjie ; Drew, David A. ; Ogino, Shuji ; Giovannucci, Edward L. ; Cao, Yin ; Song, Mingyang ; Nguyen, Long H. ; Chan, Andrew T.

Aspirin reduces the risk of colorectal cancer (CRC). Identifying individuals more likely to benefit from regular aspirin use for CRC prevention is a high priority.To assess whether aspirin use is associated with the risk of CRC across different lifestyle risk factors.A prospective cohort study among women in the Nurses’ Health Study (1980-2018) and men in the Health Professionals Follow-Up Study (1986-2018) was conducted. Data analysis was performed from October 1, 2021, to May 22, 2023.A [...]

Mené en Allemagne par questionnaire auprès de 11 286 étudiants, cet essai randomisé évalue l'effet, sur la prévalence du tabagisme à 24 mois, d'une application mobile simulant le vieillissement cutané prématuré du visage lié à l'usage de tabac

Evaluation of a medical student-delivered smoking prevention program utilizing a face-aging mobile app for secondary schools in Germany: The Education Against Tobacco Cluster-Randomized Controlled Trial

Brinker, Titus J. ; Krieghoff-Henning, Eva I. ; Suhre, Janina L. ; Silchmüller, Marc Phillipp ; Divizieva, Evgenia ; Wilhelm, Jilada ; Hillebrand, Gabriel ; Haney, Ailís C. ; Srivastava, Aayushi ; Haney, Caelán M. ; Seeger, Werner ; Penka, Dominik ; Gall, Henning ; Gaim, Benedikt ; Glisic, Lazar ; Stark, Tobias ; Swoboda, Susanne M. ; Baumermann, Sonja ; Brieske, Christian M. ; Jakob, Lena ; Fahrner, Hannah Maria ; Anhuef, Ole ; Schmidt, Selina Marisa ; Alfitian, Jonas ; Taha, Lava ; Beißwenger, Hanna ; Groneberg, David A. ; Thomas, Roger E. ; Frohling, Stefan ; von Kalle, Christof ; Baudson, Tanja Gabriele ; Buslaff, Fabian ; Mons, Ute

Background: To reduce smoking uptake in adolescents, the medical students' network Education Against Tobacco (EAT) has developed a school-based intervention involving a face-aging mobile app (Smokerface). Methods: A two-arm cluster-randomized controlled trial was conducted, evaluating the 2016 EAT intervention, which employed the mobile app Smokerface and which was delivered by medical students. Schools were randomized to intervention or control group. Surveys were conducted at baseline [...]