A partir d'une revue systématique de la littérature publiée jusqu'en mai 2024 (71 articles), cette étude analyse l'association entre une exposition aux métaux et le risque de cancer

The preventive and carcinogenic effect of metals on cancer: a systematic review

Khoshakhlagh, Amir Hossein ; Mohammadzadeh, Mahdiyeh ; Gruszecka-Kosowska, Agnieszka

Background: Many studies have investigated the role of metals in various types of malignancies. Considering the wide range of studies conducted in this field and the achievement of different results, the presented systematic review was performed to obtain the results of investigations on the prevention and occurrence of various types of cancer associated with metal exposures. Methods: In this review, research was conducted in the three databases: Scopus, PubMed, and Web of Science without [...]

A partir d'une revue systématique de la littérature publiée jusqu'en janvier 2024 (46 articles), cette étude analyse l'association entre une exposition au plomb (mesurée dans des échantillons biologiques) et le risque de cancer par localisation ainsi que la mortalité

Lead (Pb) in biological samples in association with cancer risk and mortality: A systematic literature review

Vagnoni, Giulia ; Bortolotti, Emma ; Checchi, Saverio ; Saieva, Calogero ; Berti, Giovanna ; Doccioli, Chiara ; Caini, Saverio

Background and aim: Lead (Pb) is a toxic heavy metal and pervasive environmental contaminant, and a class 2 A carcinogen according to the IARC classification, yet its link with cancer at several body sites remains uncertain. Here, we aimed at summarizing the scientific evidence regarding its association with cancer risk and mortality, focusing on studies that carried out Pb measurements in biological samples. Methods: We reviewed articles published in PubMed and EMBASE until January 2nd, 2024, [...]

Menée à l'aide des données d'une étude américaine portant sur 62 785 personnes, cette étude analyse l'association entre les rayonnements ambiants ultra-violets UVA ou UVB et le risque de mélanome (837 cas)

Ambient ultraviolet A, ultraviolet B and risk of melanoma in a nationwide United States cohort, 1984-2014

Cahoon, Elizabeth K ; Mandal, Soutrik ; Pfeiffer, Ruth M ; Wheeler, David C ; Sargen, Michael R ; Alexander, Bruce H ; Kitahara, Cari M ; Linet, Martha S ; Mai, Jim Z

Ultraviolet radiation (UVR) exposure is the primary risk factor for melanoma although the relationship is complex. Compared to radiation from UVB wavelengths, UVA makes up a majority of the surface solar UVR, penetrates the skin more deeply, is the principal range emitted by tanning beds, and is less filtered by sunscreens and window glass. Few studies have examined the relationship between ambient UVA and UVB and melanoma risk.Incidence rate ratios (IRRs) and 95% confidence intervals (CIs) [...]

Menée à l'aide d'échantillons salivaires prélevés chez 242 témoins et 498 patients atteints d'un carcinome épidermoïde de la tête et du cou, cette étude analyse l'association entre la consommation de tabac ou d'opium et le risque d'infection orale par le papillomavirus humain

Association of opium use and tobacco smoking with α-, β-, and γ-human papillomavirus oral infection

Karimi, Abbas ; Mohebbi, Elham ; McKay-Chopin, Sandrine ; Hadji, Maryam ; Rashidian, Hamideh ; Marzban, Maryam ; Naghibzadeh-Tahami, Ahmad ; Gholipour, Mahin ; Eslami, Hadi ; Kamangar, Farin ; Tommasino, Massimo ; Gheit, Tarik ; Zendehdel, Kazem

Head and neck squamous cell carcinomas (HNSCCs) are linked to tobacco smoking, opium use, and human papillomavirus (HPV) infection. However, little is known about the association of HPV infection with risk factors of HNSCCs, including opium and tobacco use. This cross-sectional analysis of a national multi-center case–control study in Iran included 498 HNSCC cases and 242 controls. We investigated the association of opium and tobacco use with α- (n = 21), β- (n = 46), and γ-HPV (n = 52) types [...]

Menée à l'aide d'une méthode de randomisation mendélienne et notamment de données portant sur 602 604 personnes, cette étude analyse l'association entre un reflux gastro-oesophagien (RGO) et le risque de cancer (19 localisations)

Unraveling the causality between gastroesophageal reflux disease and increased cancer risk: evidence from the UK Biobank and GWAS consortia

Wu, Gujie ; Liu, Yaqiong ; Ning, Dong ; Zhao, Mengnan ; Li, Xiaoqing ; Chang, Lu ; Hu, Qili ; Li, Yao ; Cheng, Lin ; Huang, Yiwei

Background: Gastroesophageal reflux disease (GERD) is a common condition characterized by the reflux of stomach contents into the esophagus. Despite its widespread prevalence worldwide, the causal link between GERD and various cancer risks has not been fully established, and past medical research has often underestimated or overlooked this relationship. Methods: This study performed Mendelian randomization (MR) to investigate the causal relationship between GERD and 19 different cancers. We [...]

Menée à partir de données des cohortes américaines "the Nurses’ Health Studies" et "the Health Professionals Follow-Up Study" portant sur 224 109 personnes (durée de suivi : jusqu'à 32 ans), cette étude analyse l'association entre une appendicectomie et le risque d'adénome ou de cancer colorectal

Risk of colorectal cancer and adenoma after an appendectomy: results from three large prospective cohort studies and meta-analysis

Zhang, Yiwen ; Khil, Jaewon ; Feng, Xiaoshuang ; Ugai, Tomotaka ; Ogino, Shuji ; Giovannucci, Edward

Purpose: The relationship between appendectomy and subsequent colorectal cancer risk remains unclear, and no study has examined its association with colorectal adenoma. Methods: We used data from three prospective cohorts: Health Professionals Follow-up Study, Nurses’ Health Study (NHS), and NHSII. Appendectomy history was self-reported at baseline. Colorectal cancer risk was analyzed with Cox proportional hazard models among 224,109 participants followed up to 32 years. Colorectal adenoma risk [...]

Menée à partir de données américaines portant sur 1 085 patientes atteintes d'un cancer du sein, cette étude analyse l'association entre l'indice de masse corporel et le risque de cancer du sein de survenue précoce par sous-type moléculaire et en fonction de l'origine ethnique

Obesity and Early-Onset Breast Cancer and Specific Molecular Subtype Diagnosis in Black and White Women: NIMHD Social Epigenomics Program

Sudan, Sarabjeet Kour ; Sharma, Amod ; Vikramdeo, Kunwar Somesh ; Davis, Wade ; Deshmukh, Sachin K. ; Poosarla, Teja ; Holliday, Nicolette P. ; Prodduturvar, Pranitha ; Nelson, Cindy ; Singh, Karan P. ; Singh, Ajay P. ; Singh, Seema

Epidemiologic data suggest an association of obesity with breast cancer (BC); however, obesity’s contribution to early onset and risk of diagnosis with specific molecular subtypes by race is uncertain.To examine the race-specific association of body mass index with early onset and diagnosis of specific molecular subtypes.This retrospective cohort study included patients with BC diagnosed between October 1, 2017, and March 31, 2022, at 3 University of South Alabama Mitchell Cancer Institute [...]