Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 580 du 18 octobre 2023
Lutte contre les cancers
Qualité de vie, soins de support (2)
Menée à partir de données américaines portant sur 238 470 personnes (âge : 66-94 ans), cette étude de cohorte rétrospective analyse l'évolution de l'utilisation des opioïdes en fonction de la présence d'un cancer ou non
Trends in New and Persistent Opioid Use in Older Adults with and without Cancer
Menée à partir de données américaines portant sur 238 470 personnes (âge : 66-94 ans), cette étude de cohorte rétrospective analyse l'évolution de l'utilisation des opioïdes en fonction de la présence d'un cancer ou non
Trends in New and Persistent Opioid Use in Older Adults with and without Cancer
Van Metre Baum, Laura ; K C, Madhav ; Soulos, Pamela R ; Jeffery, Molly M ; Ruddy, Kathryn J ; Lerro, Catherine C ; Lee, Hana ; Graham, David J ; Rivera, Donna R ; Leapman, Michael S ; Jairam, Vikram ; Dinan, Michaela A ; Gross, Cary P ; Park, Henry S
Background: The impact of ongoing efforts to decrease opioid use on patients with cancer remains undefined. Our objective was to determine trends in new and additional opioid use in patients with and without cancer. Methods: This is a retrospective cohort study using data from SEER-Medicare for opioid-naïve patients with solid tumor malignancies diagnosed from 2012 through 2017, and a random sample of patients without cancer. We identified 238,470 eligible patients with cancer and further [...]
Menée à partir de données portant sur 30 témoins et 30 patients atteints d'un cancer de la tête et du cou, cette étude transversale analyse les altérations de leur système somatosensoriel oral et les dysfonctionnements de leurs glandes salivaires
Oral somatosensory alterations and salivary dysfunction in head and neck cancer patients
Menée à partir de données portant sur 30 témoins et 30 patients atteints d'un cancer de la tête et du cou, cette étude transversale analyse les altérations de leur système somatosensoriel oral et les dysfonctionnements de leurs glandes salivaires
Oral somatosensory alterations and salivary dysfunction in head and neck cancer patients
Riantiningtyas, Reisya Rizki ; Valenti, Alexandre ; Dougkas, Anestis ; Bredie, Wender L. P. ; Kwiecien, Camille ; Bruyas, Amandine ; Giboreau, Agnès ; Carrouel, Florence
Purpose: Patients with head and neck cancer (HNC) are at high risk of malnutrition due to eating difficulties partly mediated by sensory alterations and salivary dysfunction. Clinical studies have mostly focused on taste and smell alterations, while changes in oral somatosensory perception are largely understudied. The study aimed to investigate oral somatosensory (tactile, texture, chemesthetic, and thermal) responses and salivary functions of HNC patients in comparison to healthy controls. [...]
Observation (7)
Menée à partir de données portant sur 287 patients atteints d'un cholangiocarcinome intrahépatique de stade avancé, cette étude de cohorte rétrospective analyse la relation entre la présence d'une cirrhose (82 cas) et la toxicité de la chimiothérapie ainsi que la survie globale
Influence of cirrhosis on outcomes of patients with advanced intrahepatic cholangiocarcinoma receiving chemotherapy
Menée à partir de données portant sur 287 patients atteints d'un cholangiocarcinome intrahépatique de stade avancé, cette étude de cohorte rétrospective analyse la relation entre la présence d'une cirrhose (82 cas) et la toxicité de la chimiothérapie ainsi que la survie globale
Influence of cirrhosis on outcomes of patients with advanced intrahepatic cholangiocarcinoma receiving chemotherapy
d’Abrigeon, Constance ; McNamara, Mairéad G. ; Le Sourd, Samuel ; Lamarca, Angela ; Lièvre, Astrid ; Bourien, Heloise ; Peinoit, Alexandre ; Uguen, Thomas ; Hubner, Richard A. ; Valle, Juan W. ; Edeline, Julien
Background: Cirrhosis is a risk factor for intrahepatic cholangiocarcinoma (iCC). However, its exact prevalence is uncertain and its impact on the management of advanced disease is not established. Methods: Retrospective analysis of patients treated with systemic chemotherapy for advanced iCC in the 1st-line setting at 2 tertiary cancer referral centres. Cirrhosis was diagnosed based on at least one element prior to any treatment: pathological diagnosis, baseline platelets <150 × 109/L, portal [...]
Menée aux Etats-Unis à partir de données portant sur 140 340 patients atteints d'un carcinome hépatocellulaire, cette étude analyse l'association entre des déterminants sociaux de santé (origine ethnique, statut socioéconomique), l'accès aux traitements et la survie
Disparities in Outcomes and Access to Therapy Options in Hepatocellular Carcinoma
Menée aux Etats-Unis à partir de données portant sur 140 340 patients atteints d'un carcinome hépatocellulaire, cette étude analyse l'association entre des déterminants sociaux de santé (origine ethnique, statut socioéconomique), l'accès aux traitements et la survie
Disparities in Outcomes and Access to Therapy Options in Hepatocellular Carcinoma
Ponce, Sara Beltrán ; Gokun, Yevgeniya ; Douglass, Francisca ; Dawson, Laura ; Miller, Eric ; Thomas, Charles R ; Pitter, Kenneth ; Conteh, Lanla ; Diaz, Dayssy A
Introduction: Hepatocellular carcinoma (HCC) disproportionately impacts racial and ethnic minorities and patients with lower socioeconomic status. These social determinants of health (SDH) lead to disparities in access to care and outcomes. We aim to understand the relationship between SDH and survival and locoregional treatment options in HCC. Methods: Utilizing the National Cancer Database, we evaluated survival and access locoregional treatments including non-transplant surgery, liver [...]
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The Psychosocial Impact of the COVID-19 Pandemic on Adolescent and Young Adult Cancer Survivors in the United States: An Integrative Review
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The Psychosocial Impact of the COVID-19 Pandemic on Adolescent and Young Adult Cancer Survivors in the United States: An Integrative Review
Adolescent and young adult cancer survivors (AYAs) are uniquely challenged with navigating health care systems during an important developmental phase of life. During the Coronavirus disease 2019 (COVID-19) pandemic, many people experienced social isolation, mental health symptoms, and schooling and employment changes, which may have affected vulnerable AYA cancer survivors. The purpose of this integrative review is to explore the psychosocial impact of the COVID-19 pandemic on AYA cancer [...]
The impact of COVID-19 on patients diagnosed with melanoma, breast, and colorectal cancer
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The impact of COVID-19 on patients diagnosed with melanoma, breast, and colorectal cancer
Hanuschak, Danielle ; DePiero, Mallori ; DeMoraes, Melissa ; Bailly, Shamoore ; Rubens, Muni ; Lindeman, Paul ; Zinner, Michael ; Young, Geoffrey
Background: The COVID-19 pandemic impacted healthcare resource allocation and utilization of preventative medical services. It is unknown if there is resultant stage migration of melanoma, breast, and colorectal cancer when comparing extended time periods before and after the pandemic onset. Methods: A retrospective cohort study of melanoma, breast, and colorectal cancer patients was completed. Clinical and pathological staging was compared utilizing 12 and 22-month timeframes before and after [...]
Cancer and COVID-19: U.S. Cancer Incidence Rates During the First Year of the Pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Cancer and COVID-19: U.S. Cancer Incidence Rates During the First Year of the Pandemic
Howlader, Nadia ; Bhattacharya, Manami ; Scoppa, Steve ; Miller, Daniel ; Noone, Anne-Michelle ; Negoita, Serban ; Cronin, Kathy ; Mariotto, Angela
The COVID-19 pandemic has had a profound global impact on health care systems and patient outcomes. However, the specific effects of the pandemic on cancer incidence rates in the United States during its initial year remain unknown.In this study, we analyzed data from the SEER-22 registries, which encompass approximately 50% of the U.S. population. We investigated changes in monthly incidence rates stratified by various factors, including cancer type, stage, age group, sex, race/ethnicity, [...]
Outcomes of patients with active cancers and pre-existing cardiovascular diseases infected with SARS-CoV-2
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Outcomes of patients with active cancers and pre-existing cardiovascular diseases infected with SARS-CoV-2
Patel, Brijesh ; Chapman, Scott A. ; Neumann, Jake T. ; Visaria, Aayush ; Ogungbe, Oluwabunmi ; Wen, Sijin ; Khodaverdi, Maryam ; Makwana, Priyal ; Singh, Jasvinder A. ; Sokos, George ; Wilcox, Adam B. ; Lee, Adam M. ; Graves, Alexis ; Anzalone, Alfred Jerrod ; Manna, Amin ; Saha, Amit ; Olex, Amy ; Zhou, Andrea ; Williams, Andrew E. ; Southerland, Andrew ; Girvin, Andrew T. ; Walden, Anita ; Sharathkumar, Anjali A. ; Amor, Benjamin ; Bates, Benjamin ; Hendricks, Brian ; Alexander, Caleb ; Bramante, Carolyn ; Ward-Caviness, Cavin ; Madlock-Brown, Charisse ; Suver, Christine ; Chute, Christopher ; Dillon, Christopher ; Wu, Chunlei ; Schmitt, Clare ; Takemoto, Cliff ; Housman, Dan ; Gabriel, Davera ; Eichmann, David A. ; Mazzotti, Diego ; Brown, Don ; Boudreau, Eilis ; Hill, Elaine ; Zampino, Elizabeth ; Marti, Emily Carlson ; Pfaff, Emily R. ; French, Evan ; Koraishy, Farrukh M. ; Mariona, Federico ; Prior, Fred ; Martin, Greg ; Lehmann, Harold ; Spratt, Heidi ; Mehta, Hemalkumar ; Liu, Hongfang ; Sidky, Hythem ; Hayanga, J. W. Awori ; Pincavitch, Jami ; Clark, Jaylyn ; Harper, Jeremy Richard ; Islam, Jessica ; Ge, Jin ; Gagnier, Joel ; Saltz, Joel H. ; Saltz, Joel ; Loomba, Johanna ; Buse, John ; Mathew, Jomol ; Rutter, Joni L. ; McMurry, Julie A. ; Guinney, Justin ; Starren, Justin ; Crowley, Karen ; Bradwell, Katie Rebecca ; Walters, Kellie M. ; Wilkins, Ken ; Gersing, Kenneth R. ; Cato, Kenrick Dwain ; Murray, Kimberly ; Kostka, Kristin ; Northington, Lavance ; Pyles, Lee Allan ; Misquitta, Leonie ; Cottrell, Lesley ; Portilla, Lili ; Deacy, Mariam ; Bissell, Mark M. ; Clark, Marshall ; Emmett, Mary ; Saltz, Mary Morrison ; Palchuk, Matvey B. ; Haendel, Melissa A. ; Adams, Meredith ; Temple-O’Connor, Meredith ; Kurilla, Michael G. ; Morris, Michele ; Qureshi, Nabeel ; Safdar, Nasia ; Garbarini, Nicole ; Sharafeldin, Noha ; Sadan, Ofer ; Francis, Patricia A. ; Burgoon, Penny Wung ; Robinson, Peter ; Payne, Philip R. O. ; Fuentes, Rafael ; Jawa, Randeep ; Erwin-Cohen, Rebecca ; Patel, Rena ; Moffitt, Richard A. ; Zhu, Richard L. ; Kamaleswaran, Rishi ; Hurley, Robert ; Miller, Robert T. ; Pyarajan, Saiju ; Michael, Sam G. ; Bozzette, Samuel ; Mallipattu, Sandeep ; Vedula, Satyanarayana ; O’Neil, Shawn T. ; Setoguchi, Soko ; Hong, Stephanie S. ; Johnson, Steve ; Bennett, Tellen D. ; Callahan, Tiffany ; Topaloglu, Umit ; Sheikh, Usman ; Gordon, Valery ; Subbian, Vignesh ; Kibbe, Warren A. ; Hernandez, Wenndy ; Beasley, Will ; Cooper, Will ; Hillegass, William ; Zhang, Xiaohan Tanner ; on behalf of the, N. C. Consortium
Objective: To determine the impact of acute SARS-CoV-2 infection on patient with concomitant active cancer and CVD. Methods: The researchers extracted and analyzed data from the National COVID Cohort Collaborative (N3C) database between January 1, 2020, and July 22, 2022. They included only patients with acute SARS-CoV-2 infection, defined as a positive test by PCR 21 days before and 5 days after the day of index hospitalization. Active cancers were defined as last cancer drug administered [...]
Stage shift and relative survival for head and neck cancer during the 2020 COVID-19 pandemic: a population-based study of temporal trends
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Stage shift and relative survival for head and neck cancer during the 2020 COVID-19 pandemic: a population-based study of temporal trends
Peacock,Hanna M. ; De Gendt,Cindy ; Silversmit,Geert ; Nuyts,Sandra ; Casselman,Jan ; Machiels,Jean-Pascal ; Giusti,Francesco ; van Gool,Bart ; Vander Poorten,Vincent ; Van Eycken,Liesbet
Objective: During the first wave of the COVID-19 pandemic in 2020, non-essential health services were suspended in Belgium, and the public was ordered to socially isolate. Underdiagnosis of cancer during this period was reported worldwide. Certain risk factors for head and neck cancer (HNC) overlap with those for COVID-19 incidence and mortality, making underdiagnosis and subsequent stage shift of this potentially rapidly progressing cancer a major concern. We aimed to analyze incidence, [...]
Impact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Impact of the COVID-19 Pandemic on Lung Cancer Screening Processes in a Northeast Tertiary Health Care Network
Udelsman, Brooks V. ; Detterbeck, Frank ; Tanoue, Lynn ; Mase, Vincent ; Boffa, Daniel ; Blasberg, Justin ; Dhanasopon, Andrew ; Ely, Sora ; Mazzarelli, Louis J. ; Bader, Anna ; Woodard, Gavitt
The coronavirus disease 2019 (COVID-19) pandemic disrupted health care systems, including implementation of lung cancer screening programs. The impact and recovery from this disruption on screening processes is not well appreciated. Herein, the radiology database of a Northeast tertiary health care network was reviewed before and during the pandemic (2013–2022). In the 3 months before the pandemic, an average of 77.3 lung cancer screening with computed tomography scans (LCS-CT) were performed [...]
Cette étude analyse l'incidence du cancer du poumon aux Etats-Unis par âge et en fonction du sexe
The Burden of Lung Cancer in Women Compared With Men in the US
Cette étude analyse l'incidence du cancer du poumon aux Etats-Unis par âge et en fonction du sexe
The Burden of Lung Cancer in Women Compared With Men in the US
Jemal, Ahmedin ; Schafer, Elizabeth J. ; Sung, Hyuna ; Bandi, Priti ; Kratzer, Tyler ; Islami, Farhad ; Siegel, Rebecca L.
A previous study from the American Cancer Society reported higher lung cancer incidence in women than men younger than 50 years in the US, a reversal in the historically higher burden in men that was not fully explained by smoking differences. It is unknown, however, whether this pattern has changed in contemporary birth cohorts. Herein, we extended the previous analysis with an additional 5 years of data to monitor shifts in lung cancer incidence by age and sex.
Cette étude analyse pour l'année 2020, dans 185 pays ou territoires, l'incidence du cancer du poumon par sous-type histologique
Global variations in lung cancer incidence by histological subtype in 2020: a population-based study
Cette étude analyse pour l'année 2020, dans 185 pays ou territoires, l'incidence du cancer du poumon par sous-type histologique
Global variations in lung cancer incidence by histological subtype in 2020: a population-based study
Zhang, Yanting ; Vaccarella, Salvatore ; Morgan, Eileen ; Li, Mengmeng ; Etxeberria, Jaione ; Chokunonga, Eric ; Manraj, Shyam Shunker ; Kamate, Bakarou ; Omonisi, Abidemi ; Bray, Freddie
Background: Lung cancer is the second most common cancer worldwide, yet the distribution by histological subtype remains unknown. We aimed to quantify the global, regional, and national burden of lung cancer incidence for the four main subtypes in 185 countries and territories. Methods: In this population-based study, we used data from Cancer Incidence in Five Continents Volume XI and the African Cancer Registry Network to assess the proportions of adenocarcinoma, squamous cell carcinoma, [...]
Lessons and opportunities from improved understanding of global lung cancer histological subtypes
Cette étude analyse pour l'année 2020, dans 185 pays ou territoires, l'incidence du cancer du poumon par sous-type histologique
Lessons and opportunities from improved understanding of global lung cancer histological subtypes
Cooper, Wendy A.
In a population-based study of variations in lung cancer incidence by histological subtype in 2020, Yanting Zhang and colleagues 1 have provided, for the first time to my knowledge, data on a global scale, highlighting substantial geographical and sex-based differences. Although there are over 30 different primary lung malignancies, the four most common are adenocarcinoma, squamous cell carcinoma, large-cell carcinoma, and small-cell carcinoma, which account for most cases. 2 The different [...]
Menées aux Etats-Unis à partir de données portant sur plus de 300 000 patients atteints d'un cancer de la prostate, ces études de cohorte analysent, sur la période 2004-2020, les pratiques de fractionnement de la radiothérapie (ultra-hypofractionnement, hypofractionnement modéré et fractionnement conventionnel)
Differential Use of Radiotherapy Fractionation Regimens in Prostate Cancer
Menées aux Etats-Unis à partir de données portant sur plus de 300 000 patients atteints d'un cancer de la prostate, ces études de cohorte analysent, sur la période 2004-2020, les pratiques de fractionnement de la radiothérapie (ultra-hypofractionnement, hypofractionnement modéré et fractionnement conventionnel)
Differential Use of Radiotherapy Fractionation Regimens in Prostate Cancer
Qureshy, Sarah A. ; Diven, Marshall A. ; Ma, Xiaoyue ; Marciscano, Ariel E. ; Hu, Jim C. ; McClure, Tim D. ; Barbieri, Christopher ; Nagar, Himanshu
Technical advances in treatment of prostate cancer and a better understanding of prostate cancer biology have allowed for hypofractionated treatment courses using a higher dose per fraction. Use of ultrahypofractionated stereotactic body radiotherapy (SBRT) has also been characterized.To characterize US national trends of different RT fractionation schemes across risk groups of prostate cancer.This retrospective cohort study used data collected by the National Cancer Database (NCDB) to [...]
Increasing Use of Shorter-Course Radiotherapy for Prostate Cancer
Menées aux Etats-Unis à partir de données portant sur plus de 300 000 patients atteints d'un cancer de la prostate, ces études de cohorte analysent, sur la période 2004-2020, les pratiques de fractionnement de la radiothérapie (ultra-hypofractionnement, hypofractionnement modéré et fractionnement conventionnel)
Increasing Use of Shorter-Course Radiotherapy for Prostate Cancer
Yu, James B. ; Sun, Yilun ; Jia, Angela Y. ; Vince, Randy A., Jr ; Shoag, Jonathan E. ; Zaorsky, Nicholas G. ; Spratt, Daniel E.
Importance : Randomized clinical trials have demonstrated the noninferiority of shorter radiotherapy (RT) courses (termed hypofractionation) compared with longer RT courses in patients with localized prostate cancer. Although shorter courses are associated with cost-effectiveness, convenience, and expanded RT access, their adoption remains variable. Objective : To identify the current practice patterns of external beam RT for prostate cancer in the US. Design, Setting, and Participants : This [...]
Menée au Danemark à partir de données portant sur 13 230 patientes atteintes d'un cancer du sein HR+ traité par inhibiteurs de l'aromatase (âge médian au diagnostic : 64,4 ans ; durée médiane de suivi : 6,2 ans), cette étude de cohorte analyse l'association entre l'indice de masse corporelle et le risque de récidive
Obesity and Risk of Recurrence in Patients With Breast Cancer Treated With Aromatase Inhibitors
Menée au Danemark à partir de données portant sur 13 230 patientes atteintes d'un cancer du sein HR+ traité par inhibiteurs de l'aromatase (âge médian au diagnostic : 64,4 ans ; durée médiane de suivi : 6,2 ans), cette étude de cohorte analyse l'association entre l'indice de masse corporelle et le risque de récidive
Obesity and Risk of Recurrence in Patients With Breast Cancer Treated With Aromatase Inhibitors
Harborg, Sixten ; Cronin-Fenton, Deirdre ; Jensen, Maj-Britt Raaby ; Ahern, Thomas P. ; Ewertz, Marianne ; Borgquist, Signe
Importance : Clinical studies confirm that obesity is a risk factor for recurrence in postmenopausal women with hormone receptor–positive (HR+) breast cancer. Evidence suggests that women with obesity do not obtain similar protection from aromatase inhibitors as women with healthy weight. Objective: To examine the associations of body mass index (BMI) with recurrence. Design, Setting, and Participants : The cohort study was conducted using data from the Danish Breast Cancer Group and enrolled [...]
Approches psycho-sociales (2)
Menée à partir de données portant sur 785 femmes ayant survécu à un cancer (âge moyen au diagnostic : 25,9 ans ; âge moyen lors de l'étude : 33,2 ans), cette étude de cohorte rétrospective analyse leur perception du risque d'infertilité
Perceived and Objective Fertility Risk Among Female Survivors of Adolescent and Young Adult Cancer
Menée à partir de données portant sur 785 femmes ayant survécu à un cancer (âge moyen au diagnostic : 25,9 ans ; âge moyen lors de l'étude : 33,2 ans), cette étude de cohorte rétrospective analyse leur perception du risque d'infertilité
Perceived and Objective Fertility Risk Among Female Survivors of Adolescent and Young Adult Cancer
Din, Hena Naz ; Singh-Carlson, Savitri ; Corliss, Heather L. ; Hartman, Sheri J. ; Strong, David ; Madanat, Hala ; Su, H. Irene
Importance: Fertility is important to many survivors of adolescent and young adult (AYA) cancer, yet data on this population’s fertility perceptions and their alignment with objective infertility risk are scant. Objective : To assess whether estimated treatment gonadotoxicity and posttreatment menstrual pattern are associated with higher infertility risk perception. Design, Setting, and Participants: This retrospective cohort study included female young adult survivors of cancer diagnosed [...]
Menée par enquête auprès de 421 patients atteints d'un cancer, cette étude transversale analyse l'association entre l'évaluation cognitive de la maladie, le sentiment d'auto-efficacité, le stress et la dépression pendant la chimiothérapie
Cognitive appraisal and depression in cancer patients undergoing chemotherapy: mediation by perceived stress and self-efficacy
Menée par enquête auprès de 421 patients atteints d'un cancer, cette étude transversale analyse l'association entre l'évaluation cognitive de la maladie, le sentiment d'auto-efficacité, le stress et la dépression pendant la chimiothérapie
Cognitive appraisal and depression in cancer patients undergoing chemotherapy: mediation by perceived stress and self-efficacy
Liu, Ying ; Wen, Shuang-Shuang ; Chen, Ying ; Zheng, Jian-Wei ; Xiao, Hui-Min
Purpose: Cancer patients undergoing chemotherapy are prone to suffering a higher incidence rate of depression, leading to poor quality of life. However, how cancer affects depression is unclear. This study aimed to examine whether the relationship between cognitive appraisal and depression is mediated by perceived stress and self-efficacy in cancer patients undergoing chemotherapy. Methods: A total of 421 cancer patients undergoing chemotherapy participated in this cross-sectional survey. [...]
Analyses économiques et systèmes de soins (3)
A partir d'une revue systématique de la littérature publiée jusqu'en février 2023 (39 essais randomisés et 10 études de cohorte, 20 789 patients), cette méta-analyse compare l'efficacité, la sécurité et les coûts des biosimilaires du bévacizumab, du rituximab, du trastuzumab et des médicaments de référence en Chine, sur la période 2015-2022
Clinical Benefit, Price, and Uptake for Cancer Biosimilars vs Reference Drugs in China: A Systematic Review and Meta-Analysis
A partir d'une revue systématique de la littérature publiée jusqu'en février 2023 (39 essais randomisés et 10 études de cohorte, 20 789 patients), cette méta-analyse compare l'efficacité, la sécurité et les coûts des biosimilaires du bévacizumab, du rituximab, du trastuzumab et des médicaments de référence en Chine, sur la période 2015-2022
Clinical Benefit, Price, and Uptake for Cancer Biosimilars vs Reference Drugs in China: A Systematic Review and Meta-Analysis
Luo, Xingxian ; Du, Xin ; Li, Zhuangqi ; Liu, Jingwen ; Lv, Xufeng ; Li, Haoran ; Guo, Qixiang ; Wang, Cen ; Xue, Xuecai ; Le, Kaidi ; Jiang, Xiaomeng ; Huang, Lin ; Yang, Yue
Importance : The high cost of biologics used to treat cancer has been an increasing burden in the world. In China, the recent approval of cancer biosimilar drugs to resolve this problem is promising, but evidence of clinical benefits, price, and uptake for these drugs is still lacking. Objectives : To compare characteristics of pivotal clinical trials in China and other countries for biosimilars of bevacizumab, rituximab, and trastuzumab and investigate the efficacy or effectiveness, safety, [...]
Are Cancer Biosimilars Similar and Significant Enough to Deserve More Attention?
A partir d'une revue systématique de la littérature publiée jusqu'en février 2023 (39 essais randomisés et 10 études de cohorte, 20 789 patients), cette méta-analyse compare l'efficacité, la sécurité et les coûts des biosimilaires du bévacizumab, du rituximab, du trastuzumab et des médicaments de référence en Chine, sur la période 2015-2022
Are Cancer Biosimilars Similar and Significant Enough to Deserve More Attention?
Mao, Chen ; Li, Mengfeng
Cancer represents a major threat to public health and human lives. In recent years, anticancer biologics, such as immune checkpoint blockers and cancer driver molecule–targeting biologics, have been extensively used in the clinic to treat cancers. While they demonstrate efficacy for treating various types of cancers, the usually high cost of biologics too often imposes heavy financial burdens on individuals who need them and on tax-based health care compensation systems. Reduction of the cost [...]
Menée dans un contexte américain, cette étude compare le rapport coût-efficacité des stratégies pour traiter un séminome de stade IIA
Comparative Cost-effectiveness of Contemporary Treatment Strategies for Stage IIA Seminoma
Menée dans un contexte américain, cette étude compare le rapport coût-efficacité des stratégies pour traiter un séminome de stade IIA
Comparative Cost-effectiveness of Contemporary Treatment Strategies for Stage IIA Seminoma
Joyce, Daniel D ; Sharma, Vidit ; Wymer, Kevin M ; Moriarty, James P ; Borah, Bijan J ; Walia, Arman ; Costello, Brian A ; Pagliaro, Lance C ; Daneshmand, Siamak ; Leibovich, Bradley C ; Boorjian, Stephen A
The Surgery in Early Metastatic Seminoma (SEMS) trial examined retroperitoneal lymph node dissection (RPLND) as first-line treatment for patients with isolated 1-3cm retroperitoneal lymphadenopathy. To date, the standard of care for these patients has been either chemotherapy or radiotherapy (XRT). Herein, we evaluated the relative cost-effectiveness of these management strategies.A microsimulation model assessed the cost-effectiveness of RPLND, chemotherapy, and XRT for stage IIA seminoma. [...]
Menée aux Etats-Unis à partir de données portant sur 198 aidants familiaux de patients atteints d'un cancer de stade avancé, cette étude de cohorte analyse leur situation économique liée au traitement de la maladie (dettes, obligation de travailler pour payer les soins, etc.)
Economic costs of family caregiving for persons with advanced stage cancer: a longitudinal cohort study
Menée aux Etats-Unis à partir de données portant sur 198 aidants familiaux de patients atteints d'un cancer de stade avancé, cette étude de cohorte analyse leur situation économique liée au traitement de la maladie (dettes, obligation de travailler pour payer les soins, etc.)
Economic costs of family caregiving for persons with advanced stage cancer: a longitudinal cohort study
Van Houtven, Courtney Harold ; Miller, Katherine E. M. ; James, Hailey J. ; Blunt, Ryan ; Zhang, Wenhan ; Mariani, Abigail Cadua ; Rose, Sydney ; Alolod, Gerard P. ; Wilson-Genderson, Maureen ; Smith, Valerie A. ; Thomson, Maria D. ; Siminoff, Laura A.
Purpose: To form a multifaceted picture of family caregiver economic costs in advanced cancer. Methods: A multi-site cohort study collected prospective longitudinal data from caregivers of patients with advanced solid tumor cancers. Caregiver survey and out-of-pocket (OOP) receipt data were collected biweekly in-person for up to 24 weeks. Economic cost measures attributed to caregiving were as follows: amount of OOP costs, debt accrual, perceived economic situation, and working for pay. [...]
Sensibilisation et communication (1)
A partir d'une revue de la littérature publiée entre 2017 et 2022 (45 études, 19 pays européens), cette évalue les connaissances du grand public vis-à-vis de l'association entre une consommation d'alcool et le risque de cancer
Public awareness of the alcohol-cancer link in the EU and UK: a scoping review
A partir d'une revue de la littérature publiée entre 2017 et 2022 (45 études, 19 pays européens), cette évalue les connaissances du grand public vis-à-vis de l'association entre une consommation d'alcool et le risque de cancer
Public awareness of the alcohol-cancer link in the EU and UK: a scoping review
Kokole, Daša ; Ferreira-Borges, Carina ; Galea, Gauden ; Tran, Alexander ; Rehm, Jürgen ; Neufeld, Maria
Alcohol increases cancer risk, but less is known about public awareness of this link. This scoping review summarizes recent findings on the public awareness of alcohol as a cancer risk factor in European Union and UK.Four databases (Web of Science, MEDLINE, PsycInfo, CINAHL) were searched for papers containing data on awareness of alcohol as cancer risk factor in EU or UK published between January 2017 and December 2022, and complemented with grey literature searches.In total, 45 studies were [...]
Médecines parallèles (1)
Menée en Australie par enquête auprès de 116 professionnels de santé travaillant auprès de patients atteints d'un cancer, cette étude analyse leurs connaissances et leurs pratiques concernant le cannabis thérapeutique ou des médecines complémentaires et alternatives
Knowledge and attitudes towards medicinal cannabis and complementary and integrative medicine (CIM): a survey of healthcare professionals working i...
Menée en Australie par enquête auprès de 116 professionnels de santé travaillant auprès de patients atteints d'un cancer, cette étude analyse leurs connaissances et leurs pratiques concernant le cannabis thérapeutique ou des médecines complémentaires et alternatives
Knowledge and attitudes towards medicinal cannabis and complementary and integrative medicine (CIM): a survey of healthcare professionals working in a cancer hospital in Australia
Grant, Suzanne J. ; Gonzalez, Maria ; Heller, Gillian ; Soliman, Sarah ; Spiegel, Gretel ; Lacey, Judith
Purpose: We investigated attitudes and practices of healthcare professionals (HCPs) to medicinal cannabis (MC) and complementary and integrative medicine (CIM), including individual therapies, such as acupuncture, massage, herbs, dietary supplements, nutrition and exercise. We explored whether healthcare occupation influenced attitudes to CIM and MC; referral pathways for advice on CIM; and interest in a pharmacy service to evaluate herbs and supplements. Methods: Cross-sectional survey. All [...]
