Menée à partir de données 2010-2017 de l'Assurance maladie coréenne portant sur 4 518 704 personnes, cette étude analyse l'association entre des facteurs hépatiques ou métaboliques et le risque de cancer du rein (6 531 cas)

Effect of chronic viral hepatitis and metabolic factors on renal cancer risk in a large cohort in Republic of Korea

Wang, Hoyoung ; Nam, Su Youn ; Jo, Junwoo

Purpose: We investigated the association between hepatic and metabolic factors and renal cancer risk. Methods: This population-based cohort study included cancer-free individuals who underwent general health evaluation (January to December 2010) at the Korean National Health Insurance Service and followed-up through 2017. Hazard ratios (HR) and 95% confidence intervals (CI), determined by adjusted Cox regression analysis were used to investigate the effect of variables on renal cancer risk. [...]

Menée en Inde auprès de témoins et de 214 patients atteints d'un cancer de la vésicule biliaire (âge : 30-69 ans ; 73 % de femmes), cette étude analyse l'association entre le combustible utilisé pour la cuisson domestique et le risque de développer la maladie

Household cooking fuel and gallbladder cancer risk: a multi-centre case–control study in India

Shridhar, Krithiga ; Krishnatreya, Manigreeva ; Kumar, Ranjit ; Kondal, Dimple ; Bhattacharyya, Mouchumee ; Kalita, Banti ; Snehil, Prakriti ; Singh, Amulya K. ; Kataki, Amal Chandra ; Ghosh, Ashok ; D.Prabhakaran, ; Prabhakaran, Poornima ; Dhillon, Preet K.

Purpose: Gallbladder cancers (GBC), unique to certain geographical regions, are lethal digestive tract cancers, disproportionately affecting women, with limited information on risk factors. Methods: We evaluated the association between household cooking fuel and GBC risk in a hospital-based case–control study conducted in the North-East and East Indian states of Assam and Bihar. We explored the potential mediation by diet, fire-vents, ‘daily exposure duration’ and parity (among women). We [...]

Menée sur la période 2006-2021 auprès de 31 848 témoins et 31 848 patients souffrant d'une stéatose hépatique non alcoolique (NASH) (âge moyen : 51 ans ; 83 % d'hommes ; durée médiane de suivi : 10,1 ans), cette étude analyse l'association entre l'âge lors de la survenue de la NASH et le risque de cancer (2 415 cas)

New-Onset Age of Nonalcoholic Fatty Liver Disease and Cancer Risk

Liu, Chenan ; Liu, Tong ; Zhang, Qingsong ; Jia, Pingping ; Song, Mengmeng ; Zhang, Qi ; Ruan, Guotian ; Ge, Yizhong ; Lin, Shiqi ; Wang, Ziwen ; Xie, Hailun ; Shi, Jinyu ; Han, Ruiqin ; Chen, Yue ; Zheng, Xin ; Shen, Liuyi ; Deng, Li ; Wu, Shouling ; Shi, Hanping

The onset age of nonalcoholic fatty liver disease (NAFLD) is decreasing, and whether earlier ages of NAFLD onset are associated with increased cancer risk is currently unclear.To explore the association between NAFLD new-onset age and cancer risk.This cohort study was conducted among 179 328 participants included in the Kailuan Cohort Study between 2006 and 2021. In total, 46 100 incident NAFLD cases were identified. For each case, a participant matched by age (older or younger by 1 year) and [...]

Menée à partir de données 2006-2010 de la "UK Biobank" portant sur 463 178 personnes (durée médiane de suivi : 12,6 ans), cette étude analyse l'association entre le débit de filtration glomérulaire et le risque de carcinome à cellules rénales (1 447 cas)

Kidney Function and Risk of Renal Cell Carcinoma

Alcala, Karine ; Zahed, Hana ; Cortez Cardoso Penha, Ricardo ; Alcala, Nicolas ; Robbins, Hilary A. ; Smith-Byrne, Karl ; Martin, Richard M. ; Muller, David C. ; Brennan, Paul ; Johansson, Mattias

We evaluated the temporal association between kidney function, assessed by estimated glomerular filtration rate (eGFR), and the risk of incident renal cell carcinoma (RCC). We also evaluated whether eGFR could improve RCC risk discrimination beyond established risk factors.We analyzed the UK Biobank cohort, including 463,178 participants of whom 1,447 were diagnosed with RCC during 5,696,963 person-years of follow-up. We evaluated the temporal association between eGFR and RCC risk using [...]