A partir d'une revue systématique de la littérature publiée jusqu'en février 2023 (40 cohortes), cette méta-analyse évalue l'association entre le type de viande consommée et le risque de cancer gastrointestinal

Association of meat consumption with the risk of gastrointestinal cancers: a systematic review and meta-analysis

Di, Yan ; Ding, Lei ; Gao, Luying ; Huang, Hongyan

Background: The association between gastrointestinal cancer and types of meat consumption, including red meat, processed meat, or a combination of both, remains disputable. Therefore, we performed a systematic review and meta-analysis of prospective cohort studies to estimate the association between meat consumption and gastrointestinal cancer risk. Methods: PubMed, EmBase, and the Cochrane library databases were searched systematically for eligible studies that investigated the relation [...]

Menée en Chine à l'aide de données portant sur 575 592 personnes (durée moyenne de suivi : 8,2 ans), cette étude analyse l'association entre une longue exposistion à la pollution atmosphérique et le risque de cancer du poumon

Potential causal links of long-term air pollution with lung cancer incidence: From the perspectives of mortality and hospital admission in a large cohort study in southern China

Guo, Tong ; Chen, Shirui ; Wang, Ying ; zhang, Yuqin ; Du, Zhicheng ; Wu, Wenjing ; Chen, Shimin ; Ju, Xu ; Li, Zhiqiang ; Jing, Qinlong ; Hao, Yuantao ; Zhang, Wangjian

Evidence on the potential causal links of long-term air pollution exposure with lung cancer incidence (reflected by mortality and hospital admission) was limited, especially based on large cohorts. We examined the relationship between lung cancer and long-term exposure to particulate matter (PM, including PM2.5, PM10 and PM10-2.5) and nitrogen dioxide (NO2) among a large cohort of general Chinese adults using causal inference approaches. The study included 575 592 participants who were followed [...]

Menée aux Etats-Unis à l'aide de données de l'étude "HIV/AIDS Cancer Match Study" et de registres des cancers, cette étude évalue le risque de carcinome hépatocellulaire chez les personnes infectées par le VIH

Risk of Hepatocellular Carcinoma in People with HIV in the United States, 2001-2019

McGee-Avila, Jennifer K ; Argirion, Ilona ; Engels, Eric A ; O’Brien, Thomas R ; Horner, Marie-Josephe ; Qiao, Baozhen ; Monterosso, Analise ; Luo, Qianlai ; Shiels, Meredith S

People with HIV (PWH) have higher risk of hepatocellular carcinoma (HCC) than the general population, partly due to higher prevalence of coinfection with hepatitis B virus (HBV) or C virus (HCV).We calculated standardized incidence ratios for HCC in PWH by comparing rates from PWH in the HIV/AIDS Cancer Match Study, a population-based HIV and cancer registry linkage, to those in the general population. We used multivariable Poisson regression to estimate adjusted incidence rate ratios (aIRRs) [...]

Menée notamment à l'aide de données de la "UK Biobank" portant sur 2 000 témoins et 2 000 patients atteints d'un cancer de la vessie, cette étude identifie des interactions entre des polymorphismes à simple nucléotide associées au risque de développer la maladie

Genome-wide exploration of genetic interactions for bladder cancer risk

Yu, Evan Yi-Wen ; Tang, Qiu-Yi ; Chen, Ya-Ting ; Zhang, Yan-Xi ; Dai, Ya-Nan ; Wu, Yu-Xuan ; Li, Wen-Chao ; Mehrkanoon, Siamak ; Wang, Shi-Zhi ; Zeegers, Maurice P. ; Wesselius, Anke

Although GWASs have been conducted to investigate genetic variation of bladder tumorigenesis, little is known about genetic interactions that may influence bladder cancer (BC) risk. By leveraging large-scale participants from UK Biobank, we established a discovery database with 4000 Caucasian participants (2000 cases vs 2000 non-cases), a database with 1648 Caucasian participants (824 cases vs 824 non-cases) and 856 non-Caucasian participants (428 cases vs 428 non-cases) as validation. We then [...]