Menée aux Etats-Unis à partir de données portant sur 276 jeunes adultes ayant survécu à un cancer (âge : 18-39 ans) et sur 828 témoins, cette étude analyse, en fonction du sexe, les comorbidités, les comportements de santé, l'utilisation des soins et la qualité de vie

Sex differences in comorbid conditions, health behaviors, health care utilization, and health-related quality of life among young adult cancer survivors

Choi, Eunju ; Becker, Heather ; Lu, Qian ; Roth, Michael

Purpose: Although cancer experiences and health-related quality of life (HRQOL) differ by sex, little is known about how sex affects comorbid conditions, health behaviors, health service utilization, and HRQOL in young adult (YA) cancer survivors. We sought to determine the relationship of sex to these factors in this population. Methods: This matched case–control, cross-sectional study used data from the Texas Behavioral Risk Factor Surveillance System for 2015–2019. YA survivors aged 18–39 [...]

Menée en Australie à partir de données portant sur 351 patientes ayant été traitées pour un cancer (sein, sang ou gynécologique), cette étude analyse la présence de troubles du sommeil et les facteurs associés

Prevalence and predictors of sleep problems in women following a cancer diagnosis: results from the women’s wellness after cancer program

Edmed, Shannon L. ; Huda, M. Mamun ; Smith, Simon S. ; Seib, Charrlotte ; Porter-Steele, Janine ; Anderson, Debra ; McCarthy, Alexandra L.

Purpose: Using a discrete dataset from the Women’s Wellness after Cancer Program (WWACP), we examine the prevalence and predictors of self-reported sleep problems in women previously treated for cancer. Methods: Participants were 351 women (Mage = 53.2, SD = 8.8) from the WWACP who had completed surgery, chemotherapy and/or radiotherapy for breast, gynaecological or blood cancers within the previous 24 months. Sleep problems were measured using the Pittsburgh Sleep Quality Index (PSQI). [...]

Mené en Chine sur 100 patients atteints d'un cancer (âge moyen : 64,4 ans), cet essai randomisé évalue l'intérêt d'une intervention d'électro-acupuncture pour soulager une constipation induite par les opioïdes

Effects of Electroacupuncture for Opioid-Induced Constipation in Patients With Cancer in China: A Randomized Clinical Trial

Wang, Weiming ; Liu, Yan ; Yang, Xiaofang ; Sun, Jianhua ; Yue, Zenghui ; Lu, Dianrong ; Zhou, Kehua ; Sun, Yuanjie ; Hou, Aihua ; Zang, Zhiwei ; Jin, Xiaoqing ; Liu, Chao ; Wang, Yuhang ; Yu, Jinna ; Zhu, Lili ; Liu, Zhishun

Importance : Opioid-induced constipation (OIC) is prevalent among patients treated with opioids for cancer pain. Safe and effective therapies for OIC in patients with cancer remain an unmet need. Objective : To determine the efficacy of electroacupuncture (EA) for OIC in patients with cancer. Design, Setting, and Participants : This randomized clinical trial was conducted at 6 tertiary hospitals in China among 100 adult patients with cancer who were screened for OIC and enrolled between May 1, [...]

Menée aux Etats-Unis à partir de données portant sur 2 570 adultes ayant survécu à un cancer pédiatrique, cette étude analyse leur utilisation d'une supplémentation en vitamines et minéraux (potassium, magnésium, calcium) et l'association entre cette supplémentation et leur qualité de vie

Dietary supplement use among adult survivors of childhood cancer: A report from the St. Jude Lifetime Cohort Study

Zhang, Fang Fang ; Hudson, Melissa M. ; Chen, Fan ; Li, Zhongyu ; Huang, I-Chan ; Bhakta, Nickhill ; Ness, Kirsten K. ; Brinkman, Tara M. ; Klosky, James ; Ojha, Rohit P. ; Lanctot, Jennifer Q. ; Robison, Leslie L. ; Krull, Kevin R.

Background: Adult survivors of childhood cancer have poor adherence to nutrition guidelines and inadequate intake of dietary vitamins D and E, potassium, fiber, magnesium, and calcium. The contribution of vitamin and mineral supplement use to total nutrient intake in this population is unclear. Methods: We examined the prevalence and dose of nutrient intake among 2570 adult survivors of childhood cancer participating in the St. Jude Lifetime Cohort Study, and the association of dietary [...]

Cette étude passe en revue les facteurs associés au risque d'alopécie induite par les traitements anticancéreux chez des patientes atteintes d'un cancer du sein puis présente les stratégies pour prévenir et traiter la chute des cheveux

Hair loss during and after breast cancer therapy

Rose, Lucy ; Lustberg, Maryam ; Ruddy, Kathryn J. ; Cathcart-Rake, Elizabeth ; Loprinzi, Charles ; Dulmage, Brittany

For patients diagnosed with breast cancer, alopecia can be a distressing side effect of treatment. Major surgeries, cytotoxic chemotherapy, and endocrine therapy may result in several different types of alopecia. This article reviews the underlying mechanisms, etiology, prevention strategies, and treatment options for chemotherapy-induced alopecia, telogen effluvium, and endocrine-induced alopecia. Here, we aim to provide breast oncologists with a review of the types of hair loss related to [...]

Menée aux Etats-Unis à partir de données portant sur 817 patients atteints d'un cancer de stade avancé (âge médian : 69 ans), cette étude identifie les facteurs associés à l'utilisation des soins, à des consultations dans des services d'urgence, à des hospitalisations et au risque de décès

Associations between symptoms with healthcare utilization and death in advanced cancer patients

Farrell, Megan M. ; Jiang, Cherry ; Moss, Gabriel ; Daly, Barbara ; Weinstein, Elizabeth ; Kemmann, Matthew ; Gupta, Mona ; Lee, Richard T.

Introduction: There is limited data about assessments that are associated with increased utilization of medical services among advanced oncology patients (AOPs). We aimed to identify factors related to healthcare utilization and death in AOP. Methods: AOPs at a comprehensive cancer center were enrolled in a Center for Medicare and Medicaid Innovation program. Participants completed the Edmonton Symptom Assessment Scale (ESAS) and the Functional Assessment of Cancer Therapy–General (FACT-G) [...]

A partir d'une revue systématique de la littérature publiée jusqu'en juin 2021 (68 études incluant un total de 5 325 patients), cette méta-analyse évalue la survie globale, la survie sans progression et la survie sans progression intra-crânienne chez des patients présentant des métastases cérébrales ayant pour origine un cancer primitif extra-crânien stable ou limité

Association of Brain Metastases With Survival in Patients With Limited or Stable Extracranial Disease: A Systematic Review and Meta-analysis

Li, Alyssa Y. ; Gaebe, Karolina ; Zulfiqar, Amna ; Lee, Grace ; Jerzak, Katarzyna J. ; Sahgal, Arjun ; Habbous, Steven ; Erickson, Anders W. ; Das, Sunit

Intracranial metastatic disease (IMD) is a severe complication of cancer with profound prognostic implications. Patients with IMD in the setting of limited or stable extracranial disease (IMD-SE) may represent a unique and understudied subset of patients with IMD with superior prognosis.To evaluate overall survival (OS), progression-free survival (PFS), and intracranial PFS (iPFS) in patients with IMD-SE secondary to any primary cancer.Records were identified from MEDLINE, EMBASE, CENTRAL, and [...]

Menée à partir des données des registres américains des cancers portant sur 37 043 patients pédiatriques atteints d'un cancer de la tête et du cou (âge inférieur ou égal à 19 ans), cette étude de cohorte rétrospective analyse l'association entre des déterminants sociaux de santé (statut socioéconomique, pauvreté, chômage, niveau de revenu, niveau d'éducation, ...), le stade au diagnostic, les traitements reçus et la survie

Assessment of Social Vulnerability in Pediatric Head and Neck Cancer Care and Prognosis in the United States

Fei-Zhang, David J. ; Chelius, Daniel C. ; Patel, Urjeet A. ; Smith, Stephanie S. ; Sheyn, Anthony M. ; Rastatter, Jeff C.

Importance : Prior investigations in social determinants of health (SDoH) in pediatric head and neck cancer (HNC) have only considered a narrow scope of HNCs, SDoH, and geography while lacking inquiry into the interrelational association of SDoH with disparities in clinical pediatric HNC. Objectives : To evaluate the association of SDoH with disparities in HNC among children and adolescents and to assess which specific aspects of SDoH are most associated with disparities in dynamic and regional [...]

Menée aux Etats-Unis par enquête auprès de 454 patients atteints d'un cancer, cette étude analyse l'impact de leur détresse émotionnelle (colère, anxiété, dépression) sur leurs comportements vis-à-vis des soins palliatifs

Emotional Distress Predicts Palliative Cancer Care Attitudes: The Unique Role of Anger

Mossman, Brenna ; Perry, Laura M. ; Gerhart, James I. ; McLouth, Laurie E. ; Lewson, Ashley B. ; Hoerger, Michael

Objective : Although palliative care can mitigate emotional distress, distressed patients may be less likely to engage in timely palliative care. This study aims to investigate the role of emotional distress in palliative care avoidance by examining the associations of anger, anxiety, and depression with palliative care attitudes. Methods : Patients (N=454) with heterogeneous cancer diagnoses completed an online survey on emotional distress and palliative care attitudes. Emotional distress was [...]

Cet article souligne les enjeux liés à l'utilisation des robots conversationnels, notamment ChatGPT, par les patients atteints d'un cancer pour obtenir de l'information en santé

AI chatbots will revolutionize how cancer patients access information: ChatGPT represents a paradigm-shift

Hopkins, Ashley M ; Logan, Jessica M ; Kichenadasse, Ganessan ; Sorich, Michael J

On November 30 OpenAI enabled public access to ChatGPT, a next generation artificial-intelligence (AI) with a highly sophisticated ability to write, solve coding issues, and answer questions. This communication draws attention to the prospect that ChatGPT and its successors will become important virtual assistants to patients and healthcare providers. In our assessments, ranging from answering basic fact-based questions to responding to complex clinical questions, ChatGPT demonstrated a [...]

Menée dans 6 pays européens par enquête en ligne, cette étude identifie les facteurs entravant ou facilitant la mise en oeuvre, dans la pratique clinique, d'un outil électronique permettant d'organiser les soins de l'après-cancer

Barriers and facilitators to implementation of the interoperable Survivorship Passport (SurPass) v2.0 in 6 European countries: a PanCareSurPass online survey study

van den Oever, Selina R. ; de Beijer, Ismay A. E. ; Kremer, Leontien C. M. ; Alfes, Marie ; Balaguer, Julia ; Bárdi, Edit ; Nieto, Adela Cañete ; Cangioli, Giorgio ; Charalambous, Eliana ; Chronaki, Catherine ; Costa, Tiago ; Degelsegger, Alexander ; Düster, Vanessa ; Filbert, Anna-Liesa ; Grabow, Desiree ; Gredinger, Gerald ; Gsell, Hannah ; Haupt, Riccardo ; van Helvoirt, Maria ; Ladenstein, Ruth ; Langer, Thorsten ; Laschkolnig, Anja ; Muraca, Monica ; Rascon, Jelena ; Schreier, Günter ; Tomasikova, Zuzana ; Tormo, Maria Teresa ; Trinkunas, Justas ; Trollip, Jessica ; Trunner, Kathrin ; Uyttebroeck, Anne ; van der Pal, Helena J. H. ; Pluijm, Saskia M. F. ; Niehoff, Dorothea ; Walz, Diana ; Erdmann, Friederike ; Spix, Claudia ; Lightwood, Simone ; Bagnasco, Francesca ; Cavalca, Giacomo ; Oberti, Sara ; Nicolas, Brigitte ; Lemiere, Jurgen ; Renard, Marleen ; Michiels, An ; Kock-Schoppenhauer, Ann-Kristin ; Hildebrand, Lea ; Neumann, Anke ; Jahnke, Anne-Katrin ; Ciesiūnienė, Audronė ; Ragauskas, Paulius ; Cañete Nieto, Adela ; Balaguer Guill, Julia ; Tormo Alcañiz, Maria Teresa ; Galan, Antonio Orduña ; Correcher Palau, Marisa ; Beltrán, Lucas Cervero ; Pons Tamarit, Vicente ; Saraceno, Davide ; Berti, Alessandra ; Contino, Carlo ; Thomopulos, Nikos ; Stabile, Giulia ; Tomassi, Maria Franca ; Zamberlan, Igor ; Nichel, Barbara ; Hayn, Dieter ; Kreiner, Karl ; Beyer, Stefan ; Degelsegger-Márquez, Alexander ; Trauner, Florian ; Kremer, Leontien ; van der Pal, Heleen ; Pluijm, Saskia ; van den Oever, Selina ; de Beijer, Ismay ; Hardijzer, Emma ; den Hartogh, Jaap ; te Dorsthorst, Jeroen ; Essiaf, Samira ; Sciberras, William ; Kienesberger, Anita ; Schneider, Carina ; on behalf of the PanCareSurPass, consortium

Purpose: Long-term follow-up (LTFU) care for childhood cancer survivors (CCSs) is essential to improve and maintain their quality of life. The Survivorship Passport (SurPass) is a digital tool which can aid in the delivery of adequate LTFU care. During the European PanCareSurPass (PCSP) project, the SurPass v2.0 will be implemented and evaluated at six LTFU care clinics in Austria, Belgium, Germany, Italy, Lithuania and Spain. We aimed to identify barriers and facilitators to the implementation [...]