Menée aux Etats-Unis à l'aide de données d'une enquête réalisée sur la période 2013-2016 auprès de 7 829 fumeurs (56 % d'hommes), cette étude analyse l'association entre la perception des risques du tabac et le comportement tabagique, puis analyse l'effet d'un diagnostic de cancer (150 cas) sur cette association

Smoking Cessation and Tobacco-related Risk Perceptions among People with and without a Diagnosis of Cancer

Land, Stephanie R. ; Baker, Laura ; Twesten, Jenny ; Reyes-Guzman, Carolyn M. ; Kaufman, Annette R.

Little is known about how cancer diagnosis and tobacco-related risk perceptions are associated with smoking behavior.We used data from Waves (W) 1–3 (2013–2016) of the Population Assessment of Tobacco and Health Study to analyze longitudinal smoking behavior among adults who were current smokers and not previously diagnosed with cancer at baseline (W1; N = 7,829). The outcome was smoking cessation as of follow-up (W3). Explanatory variables were sociodemographics, other tobacco product use, [...]

Menée aux Etats-Unis à partir des données d'une enquête réalisée sur la période 2018-2019 auprès de 34 309 adultes, cette étude analyse leur volonté d'arrêter la cigarette électronique selon les antécédents de tabagisme et le type d'équipement de vapotage utilisé

Interest in quitting e-cigarette use by device type and smoking history in US adults

Palmer, Amanda M ; Rojewski, Alana M ; Carpenter, Matthew J ; Klemperer, Elias M ; Baker, Nathaniel L ; Sanford, Brandon T ; Toll, Benjamin A

Background: The use of e-cigarettes has been increasing, especially since the introduction of ‘pod’ devices to the marketplace since 2018. Most adults who vape report interest in quitting. The present study examined level of interest in e-cigarette cessation between users with varying cigarette smoking histories and device types. Methods: Data obtained from wave 5 (2018–2019) of the Population Assessment of Tobacco and Health study (n=34 309). Analyses were conducted on adult current [...]

Menée à l'aide de données portant sur 5 414 patients atteints d'hyperplasie bénigne de la prostate et sur 37 681 témoins (durée moyenne de suivi : 6,3 ans), cette étude analyse l'association entre une utilisation d'inhibiteurs de la 5-alpha réductase et le risque de cancer du rein (23 cas) et de la vessie (57 cas)

5-Alpha Reductase Inhibitors and Risk of Kidney and Bladder Cancers in Men with Benign Prostatic Hyperplasia: A Population-Based Cohort Study

Doherty, Niamh ; Cardwell, Chris R. ; Murchie, Peter ; Hill, Christopher ; Azoulay, Laurent ; Hicks, Blanaid

Background: Preclinical evidence suggests that 5-alpha reductase inhibitors, commonly used to treat benign prostatic hyperplasia, are associated with reduced incidence of certain urological cancers, yet epidemiological studies are conflicting. This study aimed to determine whether 5-alpha reductase inhibitors are associated with a reduced risk of kidney and bladder cancers. Methods: We conducted a new user active-comparator cohort study in the United Kingdom Clinical Practice Research Datalink. [...]

Menée à partir de données de suivi d'un essai randomisé portant sur 3 325 Afro-américaines (durée moyenne de suivi : 15,7 ans), cette étude analyse l'association entre une supplémentation en calcium et en vitamine D et le risque de cancer (588 cas)

Association of calcium and vitamin D supplementation with cancer incidence and cause-specific mortality in Black women: extended follow-up of the Women's Health Initiative calcium-vitamin D trial

Kato, Ikuko ; Sun, Jun ; Hastert, Theresa A. ; Abrams, Judy ; Larson, Joseph C. ; Bao, Wei ; Shadyab, Aladdin H. ; Mouton, Charles ; Qi, Lihong ; Warsinger Martin, Lisa ; Manson, JoAnn E.

Low circulating vitamin D levels are more prevalent in Black than White individuals. We analyzed the Women's Health Initiative (WHI) calcium plus vitamin D (CaD) randomized clinical trial extended follow-up data to evaluate associations between calcium plus vitamin D supplementation and incident cancer, cardiovascular disease (CVD), and cause-specific mortality endpoints among Black women. Intent-to-treat analysis was performed. Among 3325 Black women in the CaD trial who were randomized into [...]

Menée à l'aide des données d'une cohorte norvégienne portant sur 95 416 personnes, cette étude analyse l'association entre un apport en vitamine D et le risque de cancer colorectal (1 774 cas), par sous-site anatomique

Pre-diagnostic intake of vitamin D and incidence of colorectal cancer by anatomical subsites: the Norwegian Women and Cancer Cohort Study (NOWAC)

Paulsen, Elise Marlen ; Rylander, Charlotta ; Brustad, Magritt ; Jensen, Torill E.

According to the World Cancer Research Fund International, vitamin D might decrease the risk of colorectal cancer (CRC). However, less is known about the association with cancers in different subsites of the colon and in the rectum. The aim of this study was to examine associations between pre-diagnostic intake of vitamin D and risk of CRC by anatomical subsites. Data from 95 416 participants in the Norwegian Women and Cancer Cohort Study was included, and vitamin D intake was estimated from [...]

Menée à l'aide d'une simulation et de données portant sur les hommes américains hétérosexuels âgés de 15 à 84 ans en 2021, cette étude estime l'âge au moment de l'infection par le papillomavirus humain (HPV) puis évalue le bénéfice de la vaccination entre 27 et 45 ans pour la prévention du cancer de l'oropharynx lié au HPV

Upper age-limits for US male HPV-vaccination for oropharyngeal cancer prevention: A microsimulation-based modeling study

Landy, Rebecca ; Haber, Gregory ; Graubard, Barry I ; Campos, Nicole G ; Sy, Stephen ; Kim, Jane J ; Burger, Emily A ; Cheung, Li C ; Katki, Hormuzd A ; Gillison, Maura L ; Chaturvedi, Anil K

HPV-positive oropharyngeal cancer is the most common HPV-associated cancer in the United States. The age at acquisition of oral HPV infections that cause oropharyngeal cancer (causal infections) is unknown; consequently, the benefit of vaccination of US men aged 27-45 remains uncertain.We developed a microsimulation-based, individual-level, state-transition model of oral HPV16 and HPV16-positive oropharyngeal cancer among heterosexual US men aged 15-84 years, calibrated to population-level [...]