Menée aux Etats-Unis en 2020 par enquête auprès de 14 531 étudiants, cette étude analyse les perceptions des risques liés à l'utilisation non quotidienne des cigarettes électroniques, des cigarettes, des cigares, du tabac sans fumée et des narguilés

Tobacco Product Harm Perceptions Among US Middle and High School Students, 2016-2020

Glidden, Emily ; Hawkins, Nikki A. ; Jamal, Ahmed ; Wang, Teresa W.

Purpose: The aim of this study is to examine US youths’ harm perceptions toward nondaily use of e-cigarettes, cigarettes, cigars, smokeless tobacco, and hookahs. Methods: The nationally representative, cross-sectional National Youth Tobacco Survey annually assessed the following: “How much do you think people harm themselves when they [use tobacco products] some days but not every day?” Weighted estimates for 2020 were generated overall (grades 6–12) and by select demographics. Multivariable [...]

Menée à partir des données de 22 études portant sur 9 438 patients atteints d'un cancer gastrique et 20 451 témoins, cette étude analyse l'association entre la consommation de thé et le risque de développer la maladie

Tea consumption and gastric cancer: a pooled analysis from the Stomach cancer Pooling (StoP) Project consortium

Martimianaki, Georgia ; Alicandro, Gianfranco ; Pelucchi, Claudio ; Bonzi, Rossella ; Rota, Matteo ; Hu, Jinfu ; Johnson, Kenneth C. ; Rabkin, Charles S. ; Liao, Linda M. ; Sinha, Rashmi ; Zhang, Zuo-Feng ; Dalmartello, Michela ; Lunet, Nuno ; Morais, Samantha ; Palli, Domenico ; Ferraroni, Monica ; Yu, Guo-Pei ; Tsugane, Shoichiro ; Hidaka, Akihisa ; Curado, Maria Paula ; Dias-Neto, Emmanuel ; Zaridze, David ; Maximovitch, Dmitry ; Vioque, Jesús ; Garcia de la Hera, Manoli ; López-Carrillo, Lizbeth ; Hernández-Ramírez, Raúl Ulises ; Hamada, Gerson Shigueaki ; Ward, Mary H. ; Mu, Lina ; Malekzadeh, Reza ; Pourfarzi, Farhad ; Trichopoulou, Antonia ; Karakatsani, Anna ; Kurtz, Robert C. ; Lagiou, Areti ; Lagiou, Pagona ; Boccia, Stefania ; Boffetta, Paolo ; Camargo, M. Constanza ; Negri, Eva ; La Vecchia, Carlo

Background: Evidence from epidemiological studies on the role of tea drinking in gastric cancer risk remains inconsistent. We aimed to investigate and quantify the relationship between tea consumption and gastric cancer in the Stomach cancer Pooling (StoP) Project consortium. Methods: A total of 9438 cases and 20,451 controls from 22 studies worldwide were included. Odds ratios (ORs) and the corresponding 95% confidence intervals (CIs) of gastric cancer for regular versus non-regular tea [...]

A partir d'une revue systématique de la littérature publiée jusqu'en janvier 2022 (42 études), cette méta-analyse évalue l'association entre une consommation de fruits à coque et de légumineuses et le risque de cancer colorectal

Nuts and legumes consumption and risk of colorectal cancer: a systematic review and meta-analysis

Jin, Shaoyue ; Je, Youjin

Several case–control and prospective cohort studies have examined the association between the consumption of nuts and legumes and the risk of colorectal cancer. For the quantitative assessment of this association, we conducted a meta-analysis of observational studies. We searched PubMed and Web of Science databases along with hand searches for eligible studies published up to January 2022. A total of 13 studies (8 cohort studies and 5 case–control studies) on nuts consumption and 29 studies (16 [...]

Mené entre 2017 et 2019 sur 46 patients atteints de polypose adénomateuse familiale (âge moyen : 44,1 ans ; 48 % de femmes), cet essai multicentrique de phase II évalue l'intérêt, du point de vue de la réduction des effets indésirables et de la charge de polypes duodénaux à 6 mois, d'une administration hebdomadaire d'erlotinib

Phase II trial of weekly erlotinib dosing to reduce duodenal polyp burden associated with familial adenomatous polyposis

Samadder, N Jewel ; McMurray, Ryan P ; Kanth, Priyanka ; Sossenheimer, Michael ; Westover, Michelle ; Rodriguez, Luz M ; Zahrieh, David ; Foster, Nathan ; Burke, Carol A ; Stoffel, Elena ; Das, Rohit ; Cruz-Correa, Marcia ; Vilar, E ; Mankaney, Gautam ; Buttar, Navtej ; Thirumurthi, Selvi ; Turgeon, Danielle K ; Richmond, Ellen ; Umar, Asad ; Della'Zanna, Gary ; Szabo, Eva ; Limburg, Paul J

Importance: Patients with familial adenomatous polyposis (FAP) are at markedly increased risk for duodenal adenomas and cancer. Combination sulindac and erlotinib was previously shown to reduce duodenal polyp burden but was associated with a relatively high adverse event (AE) rate. Objective: To evaluate if a once weekly dosing schedule for erlotinib intervention improves the AE profile, while still providing efficacy with respect to reduced polyp burden, in participants with FAP. Design, [...]