Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Sommaire du n° 505 du 9 novembre 2021
Lutte contre les cancers
Qualité de vie, soins de support (3)
Menée par questionnaire auprès de 65 patients atteints d'une tumeur stromale gastro-intestinale traitée par inhibiteurs de tyrosine kinase, cette étude analyse les troubles du goût, de l'odorat et des sensations au niveau de la cavité buccale en lien avec les traitements anticancéreux
Taste, smell and mouthfeel disturbances in patients with gastrointestinal stromal tumors treated with tyrosine-kinase inhibitors
Menée par questionnaire auprès de 65 patients atteints d'une tumeur stromale gastro-intestinale traitée par inhibiteurs de tyrosine kinase, cette étude analyse les troubles du goût, de l'odorat et des sensations au niveau de la cavité buccale en lien avec les traitements anticancéreux
Taste, smell and mouthfeel disturbances in patients with gastrointestinal stromal tumors treated with tyrosine-kinase inhibitors
van Elst, Jip M. ; IJzerman, Nikki S. ; Mathijssen, Ron H. J. ; Steeghs, Neeltje ; Reyners, Anna K. L. ; de Haan, Jacco J.
Context : Taste, smell, and mouthfeel disturbances are underrated and underreported, but important side effects of anti-cancer medication. These symptoms are associated with a lower quality of life (QoL). The prevalence and the impact of taste, smell, and mouthfeel disturbances on daily life in patients with a gastrointestinal stromal tumor (GIST) are largely unknown. Objectives : This exploratory study assessed the prevalence and type of taste, smell, and mouthfeel disturbances and their [...]
A partir d'une revue systématique de la littérature publiée entre 2007 et 2020 (6 études, 562 patients), cette étude analyse les besoins en soins de support pour améliorer la qualité de vie des patients atteints d'un cancer du poumon
Unmet supportive care needs associated with quality of life for people with lung cancer: A systematic review of the evidence 2007–2020
A partir d'une revue systématique de la littérature publiée entre 2007 et 2020 (6 études, 562 patients), cette étude analyse les besoins en soins de support pour améliorer la qualité de vie des patients atteints d'un cancer du poumon
Unmet supportive care needs associated with quality of life for people with lung cancer: A systematic review of the evidence 2007–2020
Cochrane, Andy ; Woods, Siobhan ; Dunne, Simon ; Gallagher, Pamela
Introduction : The aim of this review was to systematically examine the evidence on the relationship between quality of life (QoL) and unmet supportive care needs in patients with lung cancer. Methods : Six databases were searched for studies published since 2007. Studies were included if they measured QoL using a standardised tool and examined its association with unmet supportive care needs in lung cancer patients. Results : Six studies involving 562 patients were included. Nearly two thirds [...]
A partir d'une revue systématique de la littérature (145 articles), cette étude analyse les effets d'une activité physique pratiquée dans l'eau sur la douleur, la fatigue, l'endurance, la mobilité, la santé cardiorespiratoire et la force musculaire des patientes atteintes d'un cancer du sein
Systematic review of the effect of aquatic therapeutic exercise in breast cancer survivors
A partir d'une revue systématique de la littérature (145 articles), cette étude analyse les effets d'une activité physique pratiquée dans l'eau sur la douleur, la fatigue, l'endurance, la mobilité, la santé cardiorespiratoire et la force musculaire des patientes atteintes d'un cancer du sein
Systematic review of the effect of aquatic therapeutic exercise in breast cancer survivors
Mur-Gimeno, Esther ; Postigo-Martin, Paula ; Cantarero-Villanueva, Irene ; Sebio-Garcia, Raquel
Background : Aquatic therapeutic exercise can be equally effective or even superior to land-based exercise in improving several clinical variables. However, there is still a lack of knowledge on the effects compared to land-based interventions particularly in breast cancer (BC) patients. Objective :The objective of this study is to examine the effects of aquatic therapeutic exercise on pain, shoulder mobility, lymphedema, cardiorespiratory fitness, muscle strength, body composition, pulmonary [...]
Observation (2)
Menée aux Etats-Unis sur la période 2005-2020, cette étude met à jour les données concernant les disparités géographiques dans l'accès aux installations de radiothérapie
Geographic Access to Radiation Therapy Facilities in the United States
Menée aux Etats-Unis sur la période 2005-2020, cette étude met à jour les données concernant les disparités géographiques dans l'accès aux installations de radiothérapie
Geographic Access to Radiation Therapy Facilities in the United States
Maroongroge, Sean ; Wallington, David G. ; Taylor, Paige A. ; Zhu, Diana ; Guadagnolo, B. Ashleigh ; Smith, Benjamin D. ; Yu, James B. ; Ballas, Leslie K.
Background: The current distribution of radiation therapy (RT) facilities in the US is not well established. A comprehensive inventory of US RT facilities was last assessed in 2005, based on data from state regulatory agencies and dosimetric quality assurance bodies. We updated this database to characterize population-level measures of geographic access to RT and analyze changes over the past 15 years. Methods: We compiled data from regulatory and accrediting organizations to identify US [...]
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Evaluation of COVID-19 Mortality and Adverse Outcomes in US Patients With or Without Cancer
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Evaluation of COVID-19 Mortality and Adverse Outcomes in US Patients With or Without Cancer
Chavez-MacGregor, Mariana ; Lei, Xiudong ; Zhao, Hui ; Scheet, Paul ; Giordano, Sharon H.
Importance : As the COVID-19 pandemic continues, understanding the clinical outcomes of patients with cancer and COVID-19 has become critically important. Objective : To compare the outcomes of patients with or without cancer who were diagnosed with COVID-19 and to identify the factors associated with mortality, mechanical ventilation, intensive care unit (ICU) stay, and hospitalization. Design, Setting, and Participants : This cohort study obtained data from the Optum de-identified COVID-19 [...]
Seroconversion rate after vaccination against COVID-19 in cancer patients - a systematic review
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Seroconversion rate after vaccination against COVID-19 in cancer patients - a systematic review
Corti, C. ; Antonarelli, G. ; Scotté, F. ; Spano, J. P. ; Barrière, J. ; Michot, J. M. ; André, F. ; Curigliano, G.
Background: Coronavirus disease 2019 (COVID-19) has affected more than 210 million people worldwide. An optimal therapeutic approach for COVID-19 remains uncertain, to date. Since the history of cancer was linked to higher mortality rates due to COVID-19, the establishment of a safe and effective vaccine coverage is crucial in these patients. However, patients with cancer were mostly excluded from vaccine candidates’ clinical trials. This systematic review aims to investigate the current [...]
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Adaptive immunity and neutralizing antibodies against SARS-CoV-2 variants of concern following vaccination in patients with cancer: the CAPTURE study
Fendler, Annika ; Shepherd, Scott T. C. ; Au, Lewis ; Wilkinson, Katalin A. ; Wu, Mary ; Byrne, Fiona ; Cerrone, Maddalena ; Schmitt, Andreas M. ; Joharatnam-Hogan, Nalinie ; Shum, Benjamin ; Tippu, Zayd ; Rzeniewicz, Karolina ; Boos, Laura Amanda ; Harvey, Ruth ; Carlyle, Eleanor ; Edmonds, Kim ; Del Rosario, Lyra ; Sarker, Sarah ; Lingard, Karla ; Mangwende, Mary ; Holt, Lucy ; Ahmod, Hamid ; Korteweg, Justine ; Foley, Tara ; Bazin, Jessica ; Gordon, William ; Barber, Taja ; Emslie-Henry, Andrea ; Xie, Wenyi ; Gerard, Camille L. ; Deng, Daqi ; Wall, Emma C. ; Agua-Doce, Ana ; Namjou, Sina ; Caidan, Simon ; Gavrielides, Mike ; MacRae, James I. ; Kelly, Gavin ; Peat, Kema ; Kelly, Denise ; Murra, Aida ; Kelly, Kayleigh ; O’Flaherty, Molly ; Dowdie, Lauren ; Ash, Natalie ; Gronthoud, Firza ; Shea, Robyn L. ; Gardner, Gail ; Murray, Darren ; Kinnaird, Fiona ; Cui, Wanyuan ; Pascual, Javier ; Rodney, Simon ; Mencel, Justin ; Curtis, Olivia ; Stephenson, Clemency ; Robinson, Anna ; Oza, Bhavna ; Farag, Sheima ; Leslie, Isla ; Rogiers, Aljosja ; Iyengar, Sunil ; Ethell, Mark ; Messiou, Christina ; Cunningham, David ; Chau, Ian ; Starling, Naureen ; Turner, Nicholas ; Welsh, Liam ; Van As, Nicholas ; Jones, Robin L. ; Droney, Joanne ; Banerjee, Susana ; Tatham, Kate C. ; O’Brien, Mary ; Harrington, Kevin ; Bhide, Shreerang ; Okines, Alicia ; Reid, Alison ; Young, Kate ; Furness, Andrew J. S. ; Pickering, Lisa ; Swanton, Charles ; Gandhi, Sonia ; Gamblin, Steve ; Bauer, David L. V. ; Kassiotis, George ; Kumar, Sacheen ; Yousaf, Nadia ; Jhanji, Shaman ; Nicholson, Emma ; Howell, Michael ; Walker, Susanna ; Wilkinson, Robert J. ; Larkin, James ; Turajlic, Samra ; The Crick, Covid-Consortium ; The, Capture Consortium
Coronavirus disease 2019 (COVID-19) antiviral response in a pan-tumor immune monitoring (CAPTURE) (NCT03226886) is a prospective cohort study of COVID-19 immunity in patients with cancer. Here we evaluated 585 patients following administration of two doses of BNT162b2 or AZD1222 vaccines, administered 12 weeks apart. Seroconversion rates after two doses were 85% and 59% in patients with solid and hematological malignancies, respectively. A lower proportion of patients had detectable titers of [...]
COVID-19 vaccination in patients with multiple myeloma: a consensus of the European Myeloma Network
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
COVID-19 vaccination in patients with multiple myeloma: a consensus of the European Myeloma Network
Ludwig, Heinz ; Sonneveld, Pieter ; Facon, Thierry ; San-Miguel, Jesus ; Avet-Loiseau, Hervé ; Mohty, Mohamad ; Mateos, María-Victoria ; Moreau, Philippe ; Cavo, Michele ; Pawlyn, Charlotte ; Zweegman, Sonja ; Engelhardt, Monika ; Driessen, Christoph ; Cook, Gordon ; Dimopoulos, Melitios A. ; Gay, Francesca ; Einsele, Hermann ; Delforge, Michel ; Caers, Jo ; Weisel, Katja ; Jackson, Graham ; Garderet, Laurent ; van de Donk, Niels ; Leleu, Xavier ; Goldschmidt, Hartmut ; Beksac, Meral ; Nijhof, Inger ; Schreder, Martin ; Abildgaard, Niels ; Hajek, Roman ; Zojer, Niklas ; Kastritis, Efstathios ; Broijl, Annemiek ; Schjesvold, Fredrik ; Boccadoro, Mario ; Terpos, Evangelos
Patients with multiple myeloma frequently present with substantial immune impairment and an increased risk for infections and infection-related mortality. The risk for infection with SARS-CoV-2 virus and resulting mortality is also increased, emphasising the importance of protecting patients by vaccination. Available data in patients with multiple myeloma suggest a suboptimal anti-SARS-CoV-2 immune response, meaning a proportion of patients are unprotected. Factors associated with poor response [...]
Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Prevalence and impact of COVID-19 sequelae on treatment and survival of patients with cancer who recovered from SARS-CoV-2 infection: evidence from the OnCovid retrospective, multicentre registry study
Pinato, David J. ; Tabernero, Josep ; Bower, Mark ; Scotti, Lorenza ; Patel, Meera ; Colomba, Emeline ; Dolly, Saoirse ; Loizidou, Angela ; Chester, John ; Mukherjee, Uma ; Zambelli, Alberto ; Dalla Pria, Alessia ; Aguilar-Company, Juan ; Ottaviani, Diego ; Chowdhury, Amani ; Merry, Eve ; Salazar, Ramon ; Bertuzzi, Alexia ; Brunet, Joan ; Lambertini, Matteo ; Tagliamento, Marco ; Pous, Anna ; Sita-Lumsden, Ailsa ; Srikandarajah, Krishnie ; Colomba, Johann ; Pommeret, Fanny ; Seguí, Elia ; Generali, Daniele ; Grisanti, Salvatore ; Pedrazzoli, Paolo ; Rizzo, Gianpiero ; Libertini, Michela ; Moss, Charlotte ; Evans, Joanne S. ; Russell, Beth ; Harbeck, Nadia ; Vincenzi, Bruno ; Biello, Federica ; Bertulli, Rossella ; Liñan, Raquel ; Rossi, Sabrina ; Carmona-García, Maria Carmen ; Tondini, Carlo ; Fox, Laura ; Baggi, Alice ; Fotia, Vittoria ; Parisi, Alessandro ; Porzio, Giampero ; Saponara, Maristella ; Cruz, Claudia Andrea ; García-Illescas, David ; Felip, Eudald ; Roqué Lloveras, Ariadna ; Sharkey, Rachel ; Roldán, Elisa ; Reyes, Roxana ; Earnshaw, Irina ; Ferrante, Daniela ; Marco-Hernández, Javier ; Ruiz-Camps, Isabel ; Gaidano, Gianluca ; Patriarca, Andrea ; Bruna, Riccardo ; Sureda, Anna ; Martinez-Vila, Clara ; Sanchez de Torre, Ana ; Cantini, Luca ; Filetti, Marco ; Rimassa, Lorenza ; Chiudinelli, Lorenzo ; Franchi, Michela ; Krengli, Marco ; Santoro, Armando ; Prat, Aleix ; Van Hemelrijck, Mieke ; Diamantis, Nikolaos ; Newsom-Davis, Thomas ; Gennari, Alessandra ; Cortellini, Alessio ; Swallow, Judith ; Chung, Chris ; Dettorre, Gino ; Chopra, Neha ; Lee, Alvin J. X. ; Sng, Christopher C. T. ; Wong, Yien Ning Sophia ; Galazi, Myria ; Benafif, Sarah ; Dileo, Palma ; Patel, Grisma ; Wu, Anjui ; Sinclair, Alasdair ; Soosaipillai, Gehan ; Jones, Eleanor ; Jackson, Amanda ; Piccart, Martine ; Colomba-Blameble, Emeline ; Cruz, Claudia A. ; Garcia Illescas, David ; Mirallas, Oriol ; Carbó, Anna ; Garcia, Isabel ; Wuerstlein, Rachel ; Mesía, Ricard ; Maluquer, Clara ; D'Avanzo, Francesca ; Tonini, Giuseppe ; Provenzano, Salvatore ; Tovazzi, Valeria ; Ficorella, Corrado ; Queirolo, Paola ; Giusti, Raffaele ; Mazzoni, Francesca ; Zoratto, Federica ; Tucci, Marco ; Berardi, Rossana ; Guida, Annalisa ; Bracarda, Sergio ; Iglesias, Maria
Background : The medium-term and long-term impact of COVID-19 in patients with cancer is not yet known. In this study, we aimed to describe the prevalence of COVID-19 sequelae and their impact on the survival of patients with cancer. We also aimed to describe patterns of resumption and modifications of systemic anti-cancer therapy following recovery from SARS-CoV-2 infection. Methods : OnCovid is an active European registry study enrolling consecutive patients aged 18 years or older with a [...]
Cancer and the risk of coronavirus disease 2019 diagnosis, hospitalisation and death: A population-based multistate cohort study including 4 618 37...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Cancer and the risk of coronavirus disease 2019 diagnosis, hospitalisation and death: A population-based multistate cohort study including 4 618 377 adults in Catalonia, Spain
Roel, Elena ; Pistillo, Andrea ; Recalde, Martina ; Fernandez-Bertolin, Sergio ; Aragon, Maria ; Soerjomataram, Isabelle ; Jenab, Mazda ; Puente, Diana ; Prieto-Alhambra, Daniel ; Burn, Edward ; Duarte-Salles, Talita
Abstract The relationship between cancer and coronavirus disease 2019 (COVID-19) infection and severity remains poorly understood. We conducted a population-based cohort study between 1 March and 6 May 2020 describing the associations between cancer and risk of COVID-19 diagnosis, hospitalisation and COVID-19-related death. Data were obtained from the Information System for Research in Primary Care (SIDIAP) database, including primary care electronic health records from ~80% of the population [...]
Delivering exercise medicine to cancer survivors: has COVID-19 shifted the landscape for how and who can be reached with supervised group exercise?
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Delivering exercise medicine to cancer survivors: has COVID-19 shifted the landscape for how and who can be reached with supervised group exercise?
Winters-Stone, Kerri M. ; Boisvert, Cassie ; Li, Fuzhong ; Lyons, Karen S. ; Beer, Tomasz M. ; Mitri, Zahi ; Meyers, Gabrielle ; Eckstrom, Elizabeth ; Campbell, Kristin L.
Purpose : Due to stay-at-home orders during COVID-19, we transitioned supervised, group, in-person resistance training interventions in two clinical trials in cancer survivors to live, online delivery using video-conferencing technology. We describe the feasibility, preliminary efficacy, and safety of live online group training and compare to in-person training. Methods : Adherence (% sessions attended), retention (% participants completing intervention), and safety (# adverse events) data of [...]
Approches psycho-sociales (2)
A partir d'une revue systématique de la littérature publiée entre 1991 et 2019 (23 études, 2 558 patients), cette méta-analyse évalue l'intérêt des interventions dispensées en ligne et sur mobile pour soulager les symptômes psychiques (anxiété, dépression, détresse émotionnelle) chez des patients atteints d'un cancer de stade avancé
The efficacy of web or mobile-based interventions to alleviate emotional symptoms in people with advanced cancer: a systematic review and meta-anal...
A partir d'une revue systématique de la littérature publiée entre 1991 et 2019 (23 études, 2 558 patients), cette méta-analyse évalue l'intérêt des interventions dispensées en ligne et sur mobile pour soulager les symptômes psychiques (anxiété, dépression, détresse émotionnelle) chez des patients atteints d'un cancer de stade avancé
The efficacy of web or mobile-based interventions to alleviate emotional symptoms in people with advanced cancer: a systematic review and meta-analysis
Kamalumpundi, Vijayvardhan ; Saeidzadeh, Seyedehtanaz ; Chi, Nai-Ching ; Nair, Rajeshwari ; Gilbertson-White, Stephanie
Purpose : This review aims to critically evaluate the efficacy of web or mobile-based (WMB) interventions impacting emotional symptoms in patients with advanced cancer. Method : Articles published from 1991 to 2019 were identified using PubMed, PsycINFO, CINAHL, and Scopus. Only interventions involving adults with advanced cancer using a WMB intervention to manage emotional symptoms were included. Risk of bias was assessed using ROBINS-I and ROB2 tools. Studies that reported mean symptom scores [...]
Menée auprès de 33 patientes ayant survécu à un cancer de l'ovaire, cette étude analyse l'intérêt d'une psychothérapie basée sur le concept de la pleine conscience pour traiter la peur de la récidive de la maladie
Mindfulness-based cognitive therapy for Fear of Recurrence in Ovarian Cancer Survivors (FROCS): a single-arm, open-label, pilot study
Menée auprès de 33 patientes ayant survécu à un cancer de l'ovaire, cette étude analyse l'intérêt d'une psychothérapie basée sur le concept de la pleine conscience pour traiter la peur de la récidive de la maladie
Mindfulness-based cognitive therapy for Fear of Recurrence in Ovarian Cancer Survivors (FROCS): a single-arm, open-label, pilot study
Cohen, Paul A. ; Musiello, Toni ; Jeffares, Stephanie ; Bennett, Kellie
Objective : Fear of recurrence is common following treatment for cancer. Our aim was to assess the feasibility of mindfulness-based cognitive therapy (MBCT) to treat fear of cancer recurrence (FCR) in ovarian cancer survivors. Methods : Investigator initiated, single-arm, open-label, pilot study. Women were eligible after completing adjuvant treatment. The intervention was an 8-week MBCT course of weekly 2-h group sessions. The primary outcome was FCR measured by the FCR inventory. Secondary [...]
Analyses économiques et systèmes de soins (1)
Menée dans 31 pays européens à partir des données GLOBOCAN, cette étude analyse les coûts associés à la perte de productivité liée à la mortalité prématurée par cancer (23 localisations) pour l'année 2018
Paid and unpaid productivity losses due to premature mortality from cancer in Europe in 2018
Menée dans 31 pays européens à partir des données GLOBOCAN, cette étude analyse les coûts associés à la perte de productivité liée à la mortalité prématurée par cancer (23 localisations) pour l'année 2018
Paid and unpaid productivity losses due to premature mortality from cancer in Europe in 2018
Ortega-Ortega, Marta ; Hanly, Paul ; Pearce, Alison ; Soerjomataram, Isabelle ; Sharp, Linda
When someone dies prematurely from cancer this represents a loss of productivity for society. This loss can be valued and provides a measure of the cancer burden. We estimated paid and unpaid productivity lost due to cancer-related premature mortality in 31 European countries in 2018. Lost productivity was estimated for all cancers combined and 23 cancer sites, overall, by region and country. Deaths aged 15 to 64 were abstracted from GLOBOCAN 2018. Unpaid time lost (housework, caring, [...]
Sensibilisation et communication (1)
Menée en Angleterre, cette étude évalue l'impact d'une campagne médiatique nationale (2016 et 2017) pour améliorer les connaissances du public sur les symptômes d'un éventuel cancer du poumon et l'inciter à consulter un médecin généraliste
An evaluation of a national mass media campaign to raise public awareness of possible lung cancer symptoms in England in 2016 and 2017
Menée en Angleterre, cette étude évalue l'impact d'une campagne médiatique nationale (2016 et 2017) pour améliorer les connaissances du public sur les symptômes d'un éventuel cancer du poumon et l'inciter à consulter un médecin généraliste
An evaluation of a national mass media campaign to raise public awareness of possible lung cancer symptoms in England in 2016 and 2017
Ball, Susan ; Hyde, Chris ; Hamilton, Willie ; Bright, Chloe J. ; Gildea, Carolynn ; Wong, Kwok F. ; Paley, Lizz ; Hill, Helen L. ; Mak, Vivian ; Moffat, Jodie ; Elliss-Brookes, Lucy
Background : A two-phase ‘respiratory symptoms’ mass media campaign was conducted in 2016 and 2017 in England raising awareness of cough and worsening shortness of breath as symptoms warranting a general practitioner (GP) visit. Method : A prospectively planned pre–post evaluation was done using routinely collected data on 15 metrics, including GP attendance, GP referral, emergency presentations, cancers diagnosed (five metrics), cancer stage, investigations (two metrics), outpatient [...]
