Menée à l'aide de données de la cohorte européenne EPIC et d'une étude australienne portant au total sur 491 714 personnes, cette étude analyse l'association entre la consommation d'alcool tout au long de la vie et le risque de cancer de l'estomac (1 225 cas)

Lifetime alcohol intake, drinking patterns over time, and risk of stomach cancer: a pooled analysis of data from two prospective cohort studies

Jayasekara, Harindra ; MacInnis, Robert J. ; Barroso, Leila Luján ; Mayen-Chacon, Ana-Lucia ; Cross, Amanda J ; Wallner, Bengt ; Palli, Domenico ; Ricceri, Fulvio ; Pala, Valeria ; Panico, Salvatore ; Tumino, Rosario ; Kühn, Tilman ; Kaaks, Rudolf ; Tsilidis, Kostas ; Sánchez, María-José ; Amiano, Pilar ; Ardanaz, Eva ; López, María Dolores Chirlaque ; Merino, Susana ; Rothwell, Joseph A. ; Boutron-Ruault, Marie-Christine ; Severi, Gianluca ; Sternby, Hanna ; Sonestedt, Emily ; Bueno-de-Mesquita, Bas ; Boeing, Heiner ; Travis, Ruth ; Sandanger, Torkjel M. ; Trichopoulou, Antonia ; Karakatsani, Anna ; Peppa, Eleni ; Tjønneland, Anne ; Yang, Yi ; Hodge, Allison M. ; Mitchell, Hazel ; Haydon, Andrew ; Room, Robin ; Hopper, John L. ; Weiderpass, Elisabete ; Gunter, Marc J. ; Riboli, Elio ; Giles, Graham G. ; Milne, Roger L. ; Agudo, Antonio ; English, Dallas R. ; Ferrari, Pietro

Alcohol consumption is causally linked to several cancers but the evidence for stomach cancer is inconclusive. In our study, the association between long-term alcohol intake and risk of stomach cancer and its subtypes was evaluated. We performed a pooled analysis of data collected at baseline from 491,714 participants in the European Prospective Investigation into Cancer and Nutrition and the Melbourne Collaborative Cohort Study. Hazard ratios (HR) and 95% confidence intervals (CI) were [...]

Menée en Chine par questionnaire auprès de 59 998 hommes (durée de suivi : 714 339 personnes-années), cette étude analyse l'association entre l'apport en matières grasses d'origine alimentaire et le risque de cancer du foie (431 cas)

Dietary fat intake and liver cancer incidence: A population-based cohort study in Chinese men

Ji, Xiao-Wei ; Wang, Jing ; Shen, Qiu-Ming ; Li, Zhuo-Ying ; Jiang, Yu-Fei ; Liu, Da-Ke ; Tan, Yu-Ting ; Li, Hong-Lan ; Xiang, Yong-Bing

To date, limited studies have focused on the association between dietary fat and liver cancer risk, especially in China. This study aims to evaluate the association between dietary fat intake and liver cancer incidence risk in men. Dietary fat intake was obtained through a validated food frequency questionnaire in a Chinese prospective cohort. The Cox regression model was utilized to estimate hazard ratios (HRs) and 95% confidence intervals (CIs). After exclusion, 59,998 recruitments were [...]

Menée au Japon entre 1995 et 1999 par questionnaire auprès de 74 070 personnes (âge moyen : 56,5 ans ; durée de suivi : 15 ans), cette étude analyse l'association entre une consommation de boissons sucrées et le risque de cancer colorectal (1 648 cas)

Sugary drink consumption and subsequent colorectal cancer risk: the Japan Public Health Center-based Prospective Cohort Study

Leung, Chi Yan ; Abe, Sarah K ; Sawada, Norie ; Ishihara, Junko ; Takachi, Ribeka ; Yamaji, Taiki ; Iwasaki, Motoki ; Hashizume, Masahiro ; Inoue, Manami ; Tsugane, Shoichiro

Background: Most studies examining the associations of sugary drink consumption on colorectal cancer risk have been conducted in Western populations. Methods: This study consisted of 74 070 participants in the Japan Public Health Center-based Prospective Study who completed a food frequency questionnaire (1995-1999). The participants were followed-up until December 2013 to investigate the associations between sugary drink consumption and colorectal cancer risk using Cox proportional hazards [...]

Menée aux Etats-Unis à l'aide de données portant sur 464 371 personnes, cette étude analyse l'association entre l'exposition à la lumière artificielle nocture et le risque de cancer de la thyroïde, en fonction du sexe

Associations between artificial light at night and risk for thyroid cancer: A large US cohort study

Zhang, Dong ; Jones, Rena R. ; James, Peter ; Kitahara, Cari M. ; Xiao, Qian

Background: Light at night (LAN) inhibits nighttime secretion of melatonin and may cause circadian disruption, which may be a risk factor for cancer. Recent studies have linked high LAN exposure with elevated breast cancer risk. Given that breast cancer may share a common hormone-dependent etiology with thyroid cancer and that circadian rhythms play a role in regulating thyroid function, the authors hypothesized that exposure to LAN is positively associated with thyroid cancer incidence. [...]

Menée à partir d'échantillons sanguins prélevés sur 474 patients atteints d'un carcinome hépatocellulaire et 586 témoins, cette étude analyse l'association entre une infection par le virus de l'hépatite E, une infection conjointe par le virus de l'hépatite B et le risque de cancer du foie, en fonction du sexe

Association between Hepatitis B and E virus infection and hepatocellular carcinoma risk

Xue, Meng ; Lin, Xiaona ; Lin, Qiu-Xiong ; Pu, Xiaoyong ; Liu, Jiumin ; Li, Xing-Fang ; Hou, Jun ; Liu, Xudong ; Chen, Ren

The role of hepatitis E virus (HEV) in developing hepatocellular carcinoma (HCC) is unclear. This study aimed to investigate the role of HE infection in HCC development and the effect of hepatitis B virus (HBV) and HEV co-infection on HCC risk. A hospital-based case-control study was conducted. A total of 474 eligible HCC cases and 586 control patients were successfully recruited. The fasting venous blood was collected from the patients at the first visited to hospital and HBV infection and HEV [...]

Menée aux Etats-Unis à partir de données 1976-2014 de registres des naissances et des cancers portant sur 20 589 témoins et sur 3 166 patients pédiatriques atteints d'un cancer (âge au diagnostic : 0-14 ans), cette étude analyse l'association entre une naissance par césarienne et le risque de cancer (19 localisations)

Cesarean section is associated with an increased risk of acute lymphoblastic leukemia and hepatoblastoma in children from Minnesota

Williams, Lindsay A ; Richardson, Michaela ; Spector, Logan G ; Marcotte, Erin L.

Background: In recent decades, Cesarean section (C-section) rates have increased. C-section is hypothesized to negatively impact the developing immune system by altering activation of the hypothalamic-pituitary-adrenal axis and the infant microbiome, among other mechanisms, thereby potentially modulating childhood cancer risk. Methods: Using linked birth and cancer registry data from Minnesota (1976-2014), we included individuals aged 0-14 at diagnosis with one of 19 cancers. Cases and controls [...]