Mené au Japon à partir de données portant sur 101 849 personnes (durée moyenne de suivi : 18,7 ans), cette étude analyse l'association entre le tabagisme ou la consommation d'alcool et le risque de cancer de la thyroïde (232 cas)

Cigarette smoking, alcohol consumption and the risk of thyroid cancer in Japan: The JPHC Study

Tanitame, Marina ; Inoue, Manami ; Yamaji, Taiki ; Iwasaki, Motoki ; Tsugane, Shoichiro ; Sawada, Norie

Background: Although cigarette smoking and alcohol consumption are established causes of cancer, most cohort studies and meta-analyses have reported inverse associations with thyroid cancer (TC) risk. However, epidemiological evidence for this possibility is limited in Asia, where TC histologic type differs from the West. Here, we examined the association between cigarette smoking or alcohol consumption and risk of TC in Japanese. Methods: We analyzed data from 101,849 Japanese of the Japan [...]

Menée par questionnaire auprès de 92 278 participants à l'essai "the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial" (durée médiane de suivi : 9,4 ans), cette étude analyse l'association entre la consommation de phytoestrogènes et le risque de cancer du pancréas (346 cas) en fonction du statut tabagique

Dietary intake of isoflavones and coumestrol and risk of pancreatic cancer in the prostate, lung, colorectal, and ovarian cancer screening trial

Liu, Chunliang ; Reger, Michael ; Fan, Hao ; Wang, Jintao ; Zhang, Jianjun

Background: Although phytoestrogens modulated pancreatic tumour growth in experimental studies, it remains unclear whether phytoestrogen intake is associated with pancreatic cancer. Methods: Of 92,278 persons who completed the Diet History Questionnaire in the Prostate, Lung, Colorectal, and Ovarian Cancer Screening Trial, 346 were diagnosed with pancreatic cancer within a median follow-up of 9.4 years. Cox proportional hazards regression was used to evaluate pancreatic cancer risk in relation [...]

A partir d'une revue systématique de la littérature publiée jusqu'en janvier 2024 (17 études), cette méta-analyse évalue l'association entre une exposition aux substances per- et polyfluoroalkyles (PFAS) et le risque de cancer de l'oesophage, de l'estomac, du côlon-rectum et du pancréas

Per- and poly-fluoroalkyl substances exposure and risk of gastrointestinal cancers: a systematic review and meta-analysis

Boffetta, Paolo ; Zheng, Tongzhang ; Seyyedsalehi, Monireh Sadat ; Zhang, Sirui ; Kappil, Elizabeth Maria

Background: Per- and poly-fluoroalkyl substances (PFASs) are a group of synthetic chemicals used since the 1940s in industrial and consumer applications. These substances are known or suspected to cause cancer, particularly kidney and testicular cancer. However, their association with other types of cancer is not well understood. This review aims to investigate the link between PFAS exposure and the risks of other cancers, including gastrointestinal cancers such as esophageal, gastric, [...]

Menée en Thaïlande à l'aide d'échantillons d'urine collectés auprès de témoins et de 591 patients atteints d'un cancer du foie ou d'une maladie hépatique chronique, cette étude analyse l'association entre les niveaux de glyphosate, d'acide aminométhylphosphonique ou d'acide phosphorique et le risque de développer ces maladies

Associations of chronic liver disease and liver cancer with glyphosate and its metabolites in Thailand

Patel, Daxesh P. ; Loffredo, Christopher A. ; Pupacdi, Benjarath ; Rabibhadana, Siritida ; Navasumrit, Panida ; Chaisaingmongkol, Jittiporn ; Toulabi, Leila ; Haznadar, Majda ; Dalal, Bhavik ; Khan, Mohammed ; Stone, Joshua ; Bhudhisawasdi, Vajarabhongsa ; Lertprasertsuke, Nirush ; Chotirosniramit, Anon ; Pairojkul, Chawalit ; Auewarakul, Chirayu U. ; Sricharunrat, Thaniya ; Phornphutkul, Kannika ; Sangrajrang, Suleeporn ; Budhu, Anuradha ; Mahidol, Chulabhorn ; Wang, Xin W. ; Gonzalez, Frank J. ; Ruchirawat, Mathuros ; Harris, Curtis C. ; the TIGER-LC Consortium

Glyphosate [N-(phosphonomethyl) glycine], a systemic herbicide, is used globally (825 million kg/year) in 750+ formulations. The International Agency for Research on Cancer classified glyphosate is a probable human carcinogen (Group 2A), but epidemiological studies have been lacking for its association with liver cancer and chronic liver disease. We analyzed urine specimens from 591 patients with newly diagnosed liver cancer, chronic liver disease (CLD), and healthy individuals from five [...]

Menée à partir de données des registres du Danemark, de la Norvège et de la Suède portant sur 3 183 316 enfants nés entre 1996 et 2018, cette étude analyse l'association entre l'utilisation d'une contraception hormonale par la mère et le risque de leucémie chez l'enfant (1 701 cas)

Maternal Use of Hormonal Contraception and Risk of Childhood Leukemia: A Scandinavian Population-based Cohort Study

Hemmingsen, Caroline H. ; Kjaer, Susanne K. ; Hjorth, Sarah ; Nörby, Ulrika ; Broe, Anne ; Pottegård, Anton ; Bénévent, Justine ; Schmiegelow, Kjeld ; Skovlund, Charlotte Wessel ; Leinonen, Maarit K. ; Nordeng, Hedvig ; Mørch, Lina S. ; Hargreave, Marie

Background: Maternal hormonal contraception use has been associated with childhood leukemia risk. However, studies are few and often based on self-reported information. Methods: Using registry data from Denmark, Norway, and Sweden, we identified 3,183,316 children (born 1996–2018) and followed them from birth until leukemia diagnosis, censoring (death, emigration, other cancer, 20th birthday) or study closure (December 31st, 2017, 2018 or 2020). We estimated hazard ratios (HRs) and 95% [...]

Menée à partir de données américaines 2016-2020 portant sur 12 612 patients atteints d'un cancer de la cavité buccale et 11 170 patients atteints d'un cancer du larynx, cette étude analyse la part de ces maladies attribuable au papillomavirus humain HPV16

The role of HPV16 in oral cavity and laryngeal cancers in the United States

Kava, Christine M ; Chaturvedi, Anil K ; Senkomago, Virginia ; Mix, Jacqueline M ; Markowitz, Lauri E ; Kreimer, Aimée R ; Unger, Elizabeth R ; Saraiya, Mona

In addition to oropharyngeal cancers, evidence suggests there may be an etiologic role for human papillomavirus (HPV) in some other head and neck cancers arising from the oral cavity and larynx. We estimated the burden of HPV16-attributable cancers of the oral cavity (ICD-O-3 site codes C02.0-C02.3, C02.9, C03.0, C03.1, C03.9, C04.0, C04.1, C04.8, C04.9,C05.0, C05.8, C05.9, C06.0-C06.2, C06.8, C06.9) and larynx (C32.0-C32.3, C32.8, C32.9) in the United States by pooling estimates from published [...]

Cette étude passe en revue les données publiées concernant le risque de second cancer primitif après un traitement à base de cellules CAR-T

Second Primary Cancer After Chimeric Antigen Receptor–T-Cell Therapy: A Review

Patel, Shyam A. ; Spiegel, Jay Y. ; Dahiya, Saurabh

The commercialization of chimeric antigen receptor–T-cell (CAR-T) therapy has changed the landscape of treatment of hematological cancers. Numerous studies from the early 2000s paved the way for cell-based targeted therapeutics, which have been established as practice-changing therapies in lymphoma, leukemia, and multiple myeloma. However, there has been some recent concern about the risk for second primary cancers (SPCs).Multiple cases of SPCs arising after CAR-T therapy have been reported to [...]

Menée à partir de données de l'Assurance maladie coréenne portant sur 4 097 812 femmes, cette étude analyse l'association entre la durée d'utilisation d'antibiotiques et le risque de cancer du sein

Association between Antibiotic Use and Subsequent Risk of Breast Cancer: A Nationwide Retrospective Cohort Study in South Korea

Hong, Jaeyi ; Park, Sun Jae ; Park, Young Jun ; Jeong, Seogsong ; Choi, Seulggie ; Chang, Jooyoung ; Kim, Hye Jun ; Song, Jihun ; Ko, Ahryoung ; Kim, Su Gyeong ; Han, Minjung ; Cho, Yoosun ; Kim, Ji Soo ; Oh, Yun Hwan ; Son, Joung Sik ; Park, Sang Min

Several studies have revealed a possible association between antibiotic use and breast cancer in the Western population of women. However, its association with the Asian population remains unclear. Data utilized in this nationwide population-based retrospective cohort study was obtained from the Korean National Health Insurance Service (NHIS) database. The study population consisted of 4,097,812 women who were followed up from January 1, 2007, to December 31, 2019. Cox proportional hazards [...]

Menée à l'aide des données d'une étude canadienne portant sur les enfants atteints d'une tumeur cérébrale diagnostiquée avant 15 ans sur la période 1997-2003, cette étude analyse l’association entre les méthodes d’accouchement, des antécédents obstétricaux ou des facteurs anthropométriques à la naissance et le risque de développer la maladie

Birth characteristics and the risk of childhood brain tumors: A case–control study in Ontario, Canada

Cheng, Sierra ; McLaughlin, John R. ; Brown, M. Catherine ; Rutka, James ; Bouffet, Eric ; Hawkins, Cynthia ; Cairney, A. Elizabeth ; Ranger, Adrianna ; Fleming, Adam J. ; Johnston, Donna L. ; Greenberg, Mark ; Malkin, David ; Hung, Rayjean J.

Various birth characteristics may influence healthy childhood development, including the risk of developing childhood brain tumors (CBTs). In this study, we aimed to investigate the association between delivery methods, obstetric history, and birth anthropometrics with the risk of CBTs. This study used data from the Childhood Brain Tumour Epidemiology Study of Ontario (CBREO) which included children 0–15 years of age and newly diagnosed with CBTs from 1997 to 2003. Multivariable logistic [...]

Menée à l'aide de données coréennes portant sur 133 630 personnes (durée moyenne de suivi : 13,5 ans), cette étude analyse l'association entre les niveaux sériques de bilirubine et le risque de cancer du poumon en fonction du sexe

Serum bilirubin subgroups and cancer risk: Insights with a focus on lung cancer

Shin, Jong Won ; Kim, Namhee ; Minh, Nguyen Thien ; Chapagain, Durga Datta ; Jee, Sun Ha

Background: Bilirubin is a potent antioxidant that neutralizes reactive oxygen species (ROS). While previous studies have predominantly focused on the association between total bilirubin and cancer risk, this study evaluates the association of different bilirubin subgroups with cancer risk in men and women. Methods: Data were derived from the Korean Cancer Prevention Study-II cohort, including 133,630 participants. Over a mean follow-up of 13.5 years, 9876 cancer cases were identified. Serum [...]

A partir d'une revue systématique de la littérature publiée jusqu'en octobre 2020 (19 études), cette étude analyse les facteurs de risque de cancer de la prostate en fonction de la présence du gène de fusion TMPRSS2:ERG

Etiology of prostate cancer with the TMPRSS2:ERG fusion: A systematic review of risk factors

McGrath, Colleen B. ; Shreves, Alaina H. ; Shanahan, Megan R. ; Guard, Hannah E. ; Nhliziyo, Manelisi V. ; Pernar, Claire H. ; Penney, Kathryn L. ; Lotan, Tamara L. ; Fiorentino, Michelangelo ; Mucci, Lorelei A. ; Stopsack, Konrad H.

The most common somatic alteration in primary prostate cancer is the TMPRSS2:ERG gene fusion, which may be caused or promoted by distinct etiologic factors. The objective of this systematic review was to assess epidemiologic evidence on etiologic factors for prostate cancer by tumor TMPRSS2:ERG fusion status in human populations. Of 3071 publications identified, 19 cohort or case–control studies from six distinct study populations were included in this systematic review. Etiologic factors [...]