Menée à partir de données de la cohorte européenne "EPIC" portant sur 450 111 personnes (dure médiane de suivi : 14,1 ans), cette étude analyse l'association entre la biodiversité alimentaire et le risque de cancer de gastro-intestinal (10 705 cas)

Food biodiversity and gastrointestinal cancer risk in nine European countries: Analysis within a prospective cohort study

Huybrechts, Inge ; Chimera, Bernadette ; Hanley-Cook, Giles T. ; Biessy, Carine ; Deschasaux-Tanguy, Mélanie ; Touvier, Mathilde ; Kesse-Guyot, Emmanuelle ; Srour, Bernard ; Baudry, Julia ; Berlivet, Justine ; Casagrande, Corinne ; Nicolas, Genevieve ; Lopez, Jessica Blanco ; Millett, Christopher J. ; Cakmak, Emine Koc ; Robinson, Oliver J. K. ; Murray, Kris A. ; Schulze, Matthias B. ; Masala, Giovanna ; Guevara, Marcela ; Bodén, Stina ; Cross, Amanda J. ; Tsilidis, Kostas ; Heath, Alicia K. ; Panico, Salvatore ; Amiano, Pilar ; Huerta, José Ma ; Key, Tim ; Ericson, Ulrika ; Stocks, Tanja ; Lundblad, Marie Wasmuth ; Skeie, Guri ; Sacerdote, Carlotta ; Katzke, Verena ; Playdon, Mary C. ; Ferrari, Pietro ; Vineis, Paolo ; Lachat, Carl ; Gunter, Marc J.

Background: Food biodiversity in human diets has potential co-benefits for both public health and sustainable food systems. However, current evidence on the potential relationship between food biodiversity and cancer risk, and particularly gastrointestinal cancers typically related to diet, remains limited. This study evaluated how dietary species richness (DSR) was associated with gastrointestinal cancer risk in a pan-European population. Methods: Associations between DSR and subsequent [...]

Menée à partir de données portant sur 9 752 témoins et 3 220 patients atteints d'un cancer de l'estomac, cette étude compare l'effet chimiopréventif de l'aspirine et des statines

Aspirin but not statins is inversely related to gastric cancer with a duration–risk effect: Results from the Stomach Cancer Pooling Project Consortium

Pastorino, Roberta ; Pires Marafon, Denise ; Sassano, Michele ; Hoxhaj, Ilda ; Pelucchi, Claudio ; Liao, Linda M. ; Rabkin, Charles S. ; Sinha, Rashmi ; Lunet, Nuno ; Morais, Samantha ; Zaridze, David ; Maximovich, Dmitry ; Aragonés, Nuria ; Castaño-Vinyals, Gemma ; Gómez-Acebo, Inés ; López-Carrillo, Lizbeth ; López-Cervantes, Malaquias ; Bonzi, Rossella ; Turati, Federica ; Boffetta, Paolo ; Camargo, Maria Constanza ; Curado, Maria Paula ; Vioque, Jesús ; Zhang, Zuo-Feng ; Negri, Eva ; La Vecchia, Carlo ; Boccia, Stefania

Background: Aspirin and statins have been suggested to have potential chemopreventive effects against gastric cancer (GC), although the results of previous studies have been inconsistent. This study therefore aimed to investigate the association between the use of aspirin and statins and GC. Methods: A pooled analysis of seven case-control studies within the Stomach Cancer Pooling Project, including 3220 cases and 9752 controls, was conducted. Two-stage modeling analyses were used to estimate [...]

Cette étude estime l'effet d'actions de prévention pour réduire l'incidence des cancers aux Etats-Unis jusqu'en 2045

Accelerating Progress to Reduce the Cancer Burden through Prevention and Control in the US

Goddard, Katrina A B ; Feuer, Eric J ; Umar, Asad ; Castle, Philip E

Improvements in cancer prevention and control are poised to be main contributors in reducing the burden of cancer in the US. We quantify top opportunities to accelerate progress using projected life years gained (LYG) and deaths averted as measures. We project that over the next 25 years, realistic gains from tobacco control can contribute 0.4 to 17 million additional LYG per intervention and 8.4 million additional LYG from improving uptake of screening programs over the lifetime of 25 annual [...]