Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 608 du 14 juin 2024
Facteurs exogènes : Tabac (1)
Cette étude fait le point sur l'évolution, chez les femmes, des maladies pulmonaires liées au tabagisme
Smoking and pulmonary health in women: A narrative review and behavioral health perspective
Cette étude fait le point sur l'évolution, chez les femmes, des maladies pulmonaires liées au tabagisme
Smoking and pulmonary health in women: A narrative review and behavioral health perspective
Menson, Katherine E. ; Coleman, Sulamunn R. M.
Objective: Cigarette smoking prevalence has declined slower among women than men, and smoking-related pulmonary disease (PD) has risen dramatically among women. Given these trends, there is a critical need to understand and mitigate PD risk among women who smoke. The purpose of this narrative review and commentary is to highlight important evidence from the literature on smoking and PD among women. Methods: This review focuses broadly on examining cigarette smoking and PD among women within six [...]
Facteurs exogènes : Nutrition et activité physique (1)
Menée à partir de données internationales portant sur 723 326 personnes (durée médiane de suivi : au moins 11 ans), cette étude analyse l'association entre l'obésité, l'activité physique ou l'alimentation et le risque de cancer des voies biliaires (839 cas)
Dietary intake, obesity, and physical activity in association with biliary tract cancer risk: Results from meta-analyses of individual-level data f...
Menée à partir de données internationales portant sur 723 326 personnes (durée médiane de suivi : au moins 11 ans), cette étude analyse l'association entre l'obésité, l'activité physique ou l'alimentation et le risque de cancer des voies biliaires (839 cas)
Dietary intake, obesity, and physical activity in association with biliary tract cancer risk: Results from meta-analyses of individual-level data from prospective cohort studies of 723,326 adults
Gunchick, Valerie ; Wen, Wanqing ; Jia, Guochong ; Roberts, Lewis R. ; Koshiol, Jill ; Shu, Xiao-Ou ; Zheng, Wei
Biliary tract cancer (BTC) is a rare and aggressive malignancy with increasing incidence. Most BTC cases are diagnosed with metastatic disease which carries a 5-year survival rate of <5%. Physical activity, diet, and obesity might be associated with BTC risk, but studies have been limited particularly in African descendants. We addressed this knowledge gap by evaluating associations of BTC risk with obesity, physical activity, and dietary intakes in 723,326 adult participants in four cohort [...]
Facteurs exogènes : Autres (3)
Menée auprès de 724 patients atteints d'un cancer traité par immunothérapie à base de lymphocytes CAR-T, cette étude analyse le risque de lymphome à cellules T lié au traitement
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy
Menée auprès de 724 patients atteints d'un cancer traité par immunothérapie à base de lymphocytes CAR-T, cette étude analyse le risque de lymphome à cellules T lié au traitement
Risk of Second Tumors and T-Cell Lymphoma after CAR T-Cell Therapy
Mark P. Hamilton ; Takeshi Sugio ; Troy Noordenbos ; Shuyu Shi ; Philip L. Bulterys ; Chih Long Liu ; Xiaoman Kang ; Mari N. Olsen ; Zinaida Good ; Saurabh Dahiya ; Matthew J. Frank ; Bita Sahaf ; Crystal L. Mackall ; Dita Gratzinger ; Maximilian Diehn ; Ash A. Alizadeh ; David B. Miklos
BACKGROUND: The risk of second tumors after chimeric antigen receptor (CAR) T-cell therapy, especially the risk of T-cell neoplasms related to viral vector integration, is an emerging concern. METHODS: We reviewed our clinical experience with adoptive cellular CAR T-cell therapy at our institution since 2016 and ascertained the occurrence of second tumors. In one case of secondary T-cell lymphoma, a broad array of molecular, genetic, and cellular techniques were used to interrogate the tumor, [...]
Indolent CD4+ CAR T-Cell Lymphoma after Cilta-cel CAR T-Cell Therapy
Menée auprès de 724 patients atteints d'un cancer traité par immunothérapie à base de lymphocytes CAR-T, cette étude analyse le risque de lymphome à cellules T lié au traitement
Indolent CD4+ CAR T-Cell Lymphoma after Cilta-cel CAR T-Cell Therapy
Metin Ozdemirli ; Thomas M. Loughney ; Emre Deniz ; Joeffrey J. Chahine ; Maher Albitar ; Stefania Pittaluga ; Sam Sadigh ; Philippe Armand ; Aykut Uren ; Kenneth C. Anderson
Indolent CD4+ cytotoxic chimeric antigen receptor (CAR) T-cell lymphoma involving the small intestine was diagnosed in a patient who had previously received ciltacabtagene autoleucel (cilta-cel) CAR T-cell therapy for treatment of myeloma. Targeted messenger RNA sequencing revealed the presence of CAR gene product in tumor cells. Whole-genome sequencing of samples of tumor and peripheral blood identified a single lentiviral insertion site within the second intron of the SSU72 gene. In addition, [...]
T-Cell Cancer after CAR T-Cell Therapy
Menée auprès de 724 patients atteints d'un cancer traité par immunothérapie à base de lymphocytes CAR-T, cette étude analyse le risque de lymphome à cellules T lié au traitement
T-Cell Cancer after CAR T-Cell Therapy
Emily Mitchell ; George S. Vassiliou
The last three decades have seen dramatic advances in the use of immunotherapies to treat cancer, primarily in the form of monoclonal antibodies targeting cancer cells directly or recruiting the immune system against them. More recently, immune cells themselves are being used as anticancer treatments, led by chimeric antigen receptor (CAR) T cells, genetically modified autologous T cells that are manufactured to express a CAR gene. CAR genes are engineered to code for a transmembrane protein [...]
A partir d'une revue systématique de la littérature publiée jusqu'en octobre 2023 (4 études, 50 402 patientes), cette méta-analyse évalue l'association entre une utilisation de médicaments antipsychotiques et le risque de cancer gynécologique
The incidence risk of gynecological cancer by antipsychotic use: a meta-analysis of 50,402 patients
A partir d'une revue systématique de la littérature publiée jusqu'en octobre 2023 (4 études, 50 402 patientes), cette méta-analyse évalue l'association entre une utilisation de médicaments antipsychotiques et le risque de cancer gynécologique
The incidence risk of gynecological cancer by antipsychotic use: a meta-analysis of 50,402 patients
de Moraes, Francisco Cezar Aquino ; Sudo, Renan Yuji Ura ; Souza, Maria Eduarda Cavalcanti ; Fernandes, Marianne Rodrigues ; dos Santos, Ney Pereira Carneiro
Background: Female gynecological cancers represent a serious public health problem, with 1,398,601 new diagnoses and 671,875 deaths per year worldwide. Antipsychotics are often used in psychiatric disorders, including schizophrenia, bipolar disorder, and major depression. It is estimated that the prescription of these drugs is linked to 1,800 deaths a year in the United States, but their association with cancer remains controversial. Methods: We searched PubMed, Scopus, and Web of Science [...]
Menée à partir de données de la cohorte américaine "the Health Professionals Follow-Up Study" portant sur 49 104 personnes (durée de suivi : 30 ans), cette étude analyse l'association entre une appendicectomie et le risque de cancer de la prostate (7 253 cas)
Appendectomy and Risk of Prostate Cancer in the Health Professionals Follow-up Study
Menée à partir de données de la cohorte américaine "the Health Professionals Follow-Up Study" portant sur 49 104 personnes (durée de suivi : 30 ans), cette étude analyse l'association entre une appendicectomie et le risque de cancer de la prostate (7 253 cas)
Appendectomy and Risk of Prostate Cancer in the Health Professionals Follow-up Study
Zhang, Yiwen ; Feng, Xiaotong ; Giovannucci, Edward L.
Appendectomy is a common surgical procedure to treat appendicitis. Limited studies have examined its association with prostate cancer, with one large cohort study suggesting a significantly increased risk of overall and advanced prostate cancer, especially among younger men.A total of 49,104 men in the Health Professionals Follow-up Study were followed from 1986 to 2016. Cox proportional hazards models were applied to evaluate the association between self-reported history of appendectomy and [...]
Facteurs endogènes (1)
Menée à partir des données d'une étude portant sur 2 176 personnes (45 % d'hommes ; âge médian : 63 ans), cette étude analyse l'association entre une obésité et le risque de myélome multiple (849 cas) en fonction de l'origine ethnique et du sexe
Anthropometric traits and risk of multiple myeloma: differences by race, sex and diagnostic clinical features
Menée à partir des données d'une étude portant sur 2 176 personnes (45 % d'hommes ; âge médian : 63 ans), cette étude analyse l'association entre une obésité et le risque de myélome multiple (849 cas) en fonction de l'origine ethnique et du sexe
Anthropometric traits and risk of multiple myeloma: differences by race, sex and diagnostic clinical features
Arnold, Kevin D. ; Ong, Krystle L. ; Ravi, Gayathri ; Cutshall, Hannah ; Purnell, Kalyn ; Wessel, Meredith C. ; Godby, Kelly N. ; Bal, Susan ; Giri, Smith ; Rogers, Laura Q. ; Demark-Wahnefried, Wendy ; Davies, Faith E. ; Costa, Luciano J. ; Morgan, Gareth J. ; Birmann, Brenda M. ; Brown, Elizabeth E.
Background: Obesity is an established modifiable risk factor for multiple myeloma (MM). However, associations of obesity and MM risk in Black populations, for whom obesity and MM are more common, is less clear. Methods: Using participants enrolled in the Integrative Molecular And Genetic Epidemiology study, we evaluated the association of anthropometric traits with MM risk overall, stratified by race and sex. Among cases, we assessed the association of BMI with the presence of myeloma-defining [...]