Menée aux Etats-Unis à partir de données 2017-2022 portant sur 47 768 patients ayant survécu à un cancer, cette étude évalue la présence de troubles fonctionnels (mobilité et motricité)

Prevalence and Cancer-Specific Patterns of Functional Disability Among US Cancer Survivors, 2017-2022

Chao Cao ; Lin Yang ; Kathryn H. Schmitz ; Jennifer A. Ligibel

Purpose: To examine the prevalence and cancer-specific patterns of functional disabilities among US cancer survivors. Methods: Data from 47,768 cancer survivors and 2,432,754 noncancer adults age 18 years and older from the 2017 to 2022 Behavioral Risk Factor Surveillance System were analyzed. Functional disabilities assessed included mobility disability (ie, serious difficulty walking or climbing stairs) and self-care disability (ie, self-reported difficulty dressing or bathing). Multivariable [...]

Mené sur 128 adultes hospitalisés pour un cancer, cet essai randomisé évalue l'intérêt de la réalité virtuelle pour prendre en charge et soulager la douleur liée à la maladie et à ses traitements

Virtual reality for pain management in hospitalized patients with cancer: A randomized controlled trial

Groninger, Hunter ; Violanti, Diana ; Mete, Mihriye

Background: Hospitalized patients with cancer often experience acute and/or chronic pain. Although virtual reality (VR) has been extensively studied across a wide range of clinical settings, no studies have yet evaluated potential impact on pain management in this patient population. Methods: Prospective randomized controlled trial at an urban academic hospital comparing VR against an active control to mitigate moderate-severe cancer disease and treatment-related pain. Results: A total of 128 [...]

Cette étude compare les recommandations récentes d'organismes internationaux et de sociétés savantes concernant la prévention et la prise en charge des nausées et vomissements induits par la chimiothérapie chez les patients atteints d'un cancer

2020 ASCO, 2023 NCCN, 2023 MASCC/ESMO, and 2019 CCO: a comparison of antiemetic guidelines for the treatment of chemotherapy-induced nausea and vomiting in cancer patients

Kennedy, Samantha K. F. ; Goodall, Shannon ; Lee, Shing Fung ; DeAngelis, Carlo ; Jocko, Allison ; Charbonneau, Flay ; Wang, Katie ; Pasetka, Mark ; Ko, Yoo-Joung ; Wong, Henry C. Y. ; Chan, Adrian Wai ; Rajeswaran, Thenugaa ; Gojsevic, Milena ; Chow, Edward ; Gralla, Richard J. ; Ng, Terry L. ; Jerzak, Katarzyna J.

Chemotherapy-induced nausea and vomiting (CINV) is a common toxicity that may impair the quality of life of patients with various malignancies ranging from early to end stages. In light of frequent changes to the guidelines for optimal management of CINV, we undertook this narrative review to compare the most recent guidelines published by ASCO (2020), NCCN (2023), MASCC/ESMO (2023), and CCO (2019). The processes undertaken by each organization to evaluate existing literature were also [...]

Mené sur 112 patients atteints d'un cancer du poumon traité par chirurgie, cet essai randomisé multicentrique compare l'intérêt, du point de vue de la prise en charge des symptômes, d'un système électronique permettant aux patients de déclarer leurs symptômes et des soins standards dispensés après un traitement chirugical

Electronic Patient-Reported Outcome–Based Symptom Management Versus Usual Care After Lung Cancer Surgery: Long-Term Results of a Multicenter, Randomized, Controlled Trial

Wei Dai ; Yaqin Wang ; Jia Liao ; Xing Wei ; Zhen Dai ; Wei Xu ; Yangjun Liu ; Xin Shelley Wang ; Cecilia Pompili ; Hongfan Yu ; Yang Pu ; Yuqian Zhao ; Bangrong Cao ; Qifeng Wang ; Wenhong Feng ; Yuanqiang Zhang ; Fang Liu ; Yuanle Deng ; Jin Zhou ; Juan Li ; Shaohua Xie ; Run Xiang ; Xiang Wang ; Bo Tian ; Xiaozun Yang ; Bin Hu ; Xiaoqin Liu ; Tianpeng Xie ; Xiaojun Yang ; Xiang Zhuang ; Guibin Qiao ; Qiang Li ; Qiuling Shi

Clinical trials frequently include multiple end points that mature at different times. The initial report, typically based on the primary end point, may be published when key planned co-primary or secondary analyses are not yet available. Clinical Trial Updates provide an opportunity to disseminate additional results from studies, published in JCO or elsewhere, for which the primary end point has already been reported. We previously reported superior symptom control of electronic [...]

Menée en Australie à partir de données portant sur 758 patients décédés d'un cancer entre 2008 et 2017, cette étude de cohorte rétrospective analyse les consultations de médecine générale et les prescriptions reçues en fin de vie

Primary care usage at the end of life: a retrospective cohort study of cancer patients using linked primary and hospital care data

Grant, M. ; McCarthy, D. ; Kearney, C. ; Collins, A. ; Sundararajan, V. ; Rhee, J. ; Philip, J. ; Emery, J.

Purpose: Health service use is most intensive in the final year of a person’s life, with 80% of this expenditure occurring in hospital. Close involvement of primary care services has been promoted to enhance quality end-of-life care that is appropriate to the needs of patients. However, the relationship between primary care involvement and patients’ use of hospital care is not well described. This study aims to examine primary care use in the last year of life for cancer patients and its [...]

Menée au Canada à partir de données portant sur 5 785 patients décédés d'un cancer du poumon non à petites cellules de stade IV (âge médian : 70 ans), cette étude rétrospective analyse l'utilisation de soins de santé en dehors du domicile (soins ambulatoires, soins palliatifs, etc.) en fonction du type de traitement anticancéreux reçu en routine (traitement systémique ou non, chimiothérapie, immunothérapie ou thérapie ciblée)

Trajectories of Health Care Contact Days for Patients With Stage IV Non–Small Cell Lung Cancer

Gupta, Arjun ; Nguyen, Paul ; Kain, Danielle ; Robinson, Andrew G. ; Kulkarni, Amit A. ; Johnson, David H. ; Presley, Carolyn J. ; Blaes, Anne H. ; Rocque, Gabrielle B. ; Ganguli, Ishani ; Booth, Christopher M. ; Hanna, Timothy P.

Importance : Patients with stage IV non–small cell lung cancer (NSCLC) experience substantial morbidity and mortality. Contact days (ie, the number of days with health care contact outside the home) measure how much of a person’s life is consumed by health care, yet little is known about patterns of contact days for patients with NSCLC. Objective : To describe the trajectories of contact days in patients with stage IV NSCLC and how trajectories vary by receipt of cancer-directed treatment in [...]

Cette étude passe en revue des données portant sur les symptômes et troubles endocriniens chez les patients ayant survécu à un cancer diagnostiqué au début de l'âge adulte

Endocrine health in survivors of adult-onset cancer

Link-Rachner, Cornelia S. ; Göbel, Andy ; Jaschke, Nikolai P. ; Rachner, Tilman D.

Long-term survivors of cancer (ie, the patient who is considered cured or for whom the disease is under long-term control and unlikely to recur) are at an increased risk of developing endocrine complications such as hypothalamic–pituitary dysfunctions, hypogonadisms, osteoporosis, or metabolic disorders, particularly when intensive tumour-directed therapies are applied. Symptom severity associated with these conditions ranges from mild and subclinical to highly detrimental, affecting individual [...]

Menée par enquête en ligne auprès de 438 aidants de patients atteints d'un cancer (âge moyen : 50,5 ans), cette étude analyse l'intérêt d'un outil pour évaluer leur peur de la récidive et de la progression de la maladie

Development and validation of the CARE-FCR: A caregiver-specific measure of fear of cancer recurrence and progression

Webb, Kyra ; Sharpe, Louise ; Russell, Hayley ; Shaw, Joanne

Objectives: Fear of cancer recurring or progressing (FCR) is a concern reported by people living with cancer and caregivers alike. Whilst advances in survivor FCR have been made, less is known about caregiver FCR. As a result, measurement of caregiver FCR has relied on instruments developed for survivor populations. Findings from qualitative research indicate caregiver experiences of FCR differ. This study aimed to develop and evaluate the psychometric properties of a caregiver specific measure [...]