Menée à partir de données de la "UK Biobank" portant sur 288 802 personnes (âge moyen : 56,2 ans ; durée médiane de suivi : 8,2 ans), cette étude analyse l'association entre l'adhésion aux recommandations 2018 du "World Cancer Research Fund/American Institute for Cancer Research", évaluée à l'aide d'un système de score, et le risque de cancer

Abbreviated score to assess adherence to the 2018 WCRF/AICR Cancer Prevention Recommendations and risk of cancer in the UK Biobank

Malcomson, Fiona C. ; Parra-Soto, Solange ; Ho, Frederick K. ; Celis-Morales, Carlos ; Sharp, Linda ; Mathers, John C.

Background: The WCRF/AICR Cancer Prevention Recommendations are lifestyle-based guidelines which aim to reduce cancer risk. This study investigated, in the UK Biobank, associations between an abbreviated score to assess adherence to these Recommendations and the risk of all cancers combined and of 14 cancers for which there is strong evidence for links with diet, adiposity, and physical activity. Methods: We used data from 288,802 UK Biobank participants (mean age 56.2 years), cancer-free at [...]

Menée par questionnaire auprès de 115 830 participantes âgées de 50 à 79 ans, cette étude analyse l'association entre la qualité de l'alimentation (insulinémie, potentiel inflammatoire) et le risque de cancer du rein ainsi que la mortalité spécifique

Associations of dietary patterns with kidney cancer risk, kidney cancer-specific mortality and all-cause mortality among postmenopausal women

Jin, Qi ; Gheeya, Jinesh ; Nepal, Sushma ; Shi, Ni ; Folefac, Edmund ; Webb, Maxine Z. ; Grainger, Elizabeth M. ; Wei, Lai ; Prosek, Jason M. ; Focht, Brian C. ; Gong, Michael ; Clinton, Steven K. ; Tabung, Fred K.

Background: The empirical dietary index for hyperinsulinemia (EDIH) and empirical dietary inflammatory pattern (EDIP) are novel measures of dietary quality associated with insulin hypersecretion or chronic inflammation, respectively, whereas the Healthy Eating Index (HEI-2015) measures adherence to the Dietary Guidelines for Americans (DGA). We evaluated associations of EDIH, EDIP and HEI-2015 on the risk of both kidney cancer development and mortality. Methods: We calculated the dietary scores [...]

A partir d'une revue systématique de la littérature publiée jusqu'en mai 2023 (12 études, 5 692 patients), cette méta-analyse évalue l'association entre la consommation de vitamine B6 et le risque de cancer gastrique

Association between Vitamin B6 and Risk of Gastric Cancer: A Systematic Review and Meta-Analysis of Epidemiological Studies

Li, Cong ; He, Jianbo ; Fu, Hongjuan ; Chang, Hui

Inconsistent findings have emerged from epidemiological research investigating the association between vitamin B6 and the risk of gastric cancer. To obtain a more precise assessment, we conducted a comprehensive search of published data and performed a meta-analysis. PubMed, Web of Science, EMBASE and Cochrane Library databases were systematically searched. A total of 12 studies (5 prospective cohort and 7 case?control studies) involving 5,692 cases and 814,157 participants were included in the [...]

Menée aux Etats-Unis à l'aide de données d'une base nationale sur les demandes de remboursement de médicaments et à l'aide de registres du VIH et des cancers portant sur 63 694 patients infectés par le VIH, cette étude analyse l'association entre un traitement antirétroviral combiné et le risque de cancer

Real-world use of antiretroviral therapy and risk of cancer among people living with HIV in Texas

Horner, Marie-Josephe ; Shiels, Meredith S. ; McNeel, Timothy S. ; Monterosso, Analise ; Miller, Paige ; Pfeiffer, Ruth M. ; Engels, Eric A.

Background: Combination antiretroviral therapy (cART) may reduce cancer risk among people living with HIV (PLWH), but cancer-specific associations are incompletely understood. Methods: We linked HIV and cancer registries in Texas to a national prescription claims database. cART use was quantified as the proportion of days covered (PDC). Cox proportional hazards models assessed associations of cancer risk with cART usage, adjusting for demographic characteristics, AIDS status, and time since HIV [...]

A partir d'une revue de la littérature, cette étude analyse l'effet de la vaccination contre le papillomavirus humain (HPV) sur la réduction du risque de récidive des lésions cervicales de haut grade après un traitement chirurgical

Can prophylactic HPV vaccination reduce the recurrence of cervical lesions after surgery? Review and prospect

Han, Ling ; Zhang, Bingyi

Women with HSIL typically undergo conization/LEEP to remove cervical lesions, but the risk of HSIL lesions returning after surgical treatment remains higher than in the general population. HPV vaccination is essential to prevent cervical cancer. However, the effect of prophylactic HPV vaccination on reducing the risk of recurrent cervical lesions after surgical treatment remains unclear. This review aims to analyze and summarize the latest literature on the role of prophylactic HPV vaccine in [...]

Menée aux Pays-Bas à partir de données 2018-2021 portant sur 13 747 personnes, cette étude analyse les différences dans la réussite du sevrage tabagique en fonction du mode de délivrance des conseils comportementaux (par téléphone ou autres), du sexe, de l'âge, du niveau d'éducation et de l'état de santé

Real-life effectiveness of smoking cessation delivery modes: a comparison against telephone counselling and the role of individual characteristics and health conditions in quit success

Poole, Nikita L ; Candel, Math J J M ; Willemsen, Marc C ; van den Brand, Floor A

Professional behavioural counselling for smoking cessation can be delivered in many forms, which may not work equally well for everyone. We aim to explore in a real-world setting whether different delivery modes yield different rates of quit success and whether quit success varies based on gender, age, educational level and being treated for a health condition.We used monitoring data (n=13747) from a smoking cessation counselling provider in the Netherlands (September 2018 – August 2021) to [...]