Menée à partir de données 1982-2019 portant sur 177 709 Suédois (âge moyen : 42 ans ; durée moyenne de suivi : 9,6 ans), cette étude analyse l'association entre la capacité cardiorespiratoire et le risque de cancer du poumon (283 cas), de la prostate (1918 cas) ou du côlon-rectum (499 cas) ainsi que la mortalité spécifique (500 décès)

Association Between Cardiorespiratory Fitness and Cancer Incidence and Cancer-Specific Mortality of Colon, Lung, and Prostate Cancer Among Swedish Men

Ekblom-Bak, Elin ; Bojsen-Møller, Emil ; Wallin, Peter ; Paulsson, Sofia ; Lindwall, Magnus ; Rundqvist, Helene ; Bolam, Kate A.

Cardiorespiratory fitness (CRF) levels appear to be an important risk factor for cancer incidence and death.To examine CRF and prostate, colon, and lung cancer incidence and mortality in Swedish men, and to assess whether age moderated any associations between CRF and cancer.A prospective cohort study was conducted in a population of men who completed an occupational health profile assessment between October 1982 and December 2019 in Sweden. Data analysis was performed from June 22, 2022, to [...]

Menée par questionnaire auprès de 14 872 témoins et 1 193 patients atteints d'un cancer de la prostate, cette étude analyse l'association entre le rapport acides gras oméga-6/oméga-3 et le risque de développer la maladie, notamment chez les agriculteurs exposés aux pesticides organophosphorés

Dietary omega-6/omega-3 fatty acids and risk of prostate cancer; Is there any potential interaction by organophosphate insecticides among the agricultural health study population

Sadeghi, Homa ; Lynch, Charles F. ; Field, William R. ; Snetselaar, Linda G. ; Jones, Michael P. ; Sinha, Rashmi ; Torner, James C.

Background: In the United States (US), the average annual increase in the incidence of prostate cancer (PCa) has been 0.5% between 2013 and 2017. Although some modifiable factors have been identified as the risk factors for PCa, the effect of lower ratio of omega-6 to omega-3 fatty acids intake (N-6/N-3) remains unknown. Previous studies of the Agricultural Health Study (AHS) reported a significant positive association between PCa and selected organophosphate pesticides (OPs) including terbufos [...]

Menée à l'aide de données 1997-2011 de l'Assurance maladie taïwanaise portant sur 145 212 personnes, cette étude analyse l'association entre une utilisation quotidienne d'aspirine et le risque de carcinome hépatocellulaire chez les patients atteints d'une stéatose hépatique non alcoolique

Daily aspirin associated with a reduced risk of hepatocellular carcinoma in patients with non-alcoholic fatty liver disease: a population-based cohort study

Lee, Teng-Yu ; Hsu, Yao-Chun ; Ho, Hsiu J. ; Lin, Jaw-Town ; Chen, Yi-Ju ; Wu, Chun-Ying

Background: Emerging laboratory and animal studies suggest that aspirin may prevent non-alcoholic fatty liver disease (NAFLD)-related hepatocellular carcinoma (HCC), however clinical evidence remains lacking. Methods: Using Taiwan’s National Health Insurance Research Database, we screened 145,212 NAFLD patients from 1997 through 2011. After excluding any confounding conditions, 33,484 patients who continuously received a daily dose of aspirin for 90 days or more (treated group), along with [...]