Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 561 du 14 avril 2023
Lutte contre les cancers
Qualité de vie, soins de support (2)
Mené sur 268 patients ayant survécu à un cancer et souffrant de douleurs musculo-squelettiques chroniques et de troubles du sommeil (âge moyen : 61,4 ans), cet essai randomisé compare l'intérêt, pour améliorer la qualité de leur sommeil, d'interventions à base d'acupunture (électro-acupuncture et acupuncture auriculaire) et d'interventions utilisant des soins standards
Effect of acupuncture versus usual care on sleep quality in cancer survivors with chronic pain: Secondary analysis of a randomized clinical trial
Mené sur 268 patients ayant survécu à un cancer et souffrant de douleurs musculo-squelettiques chroniques et de troubles du sommeil (âge moyen : 61,4 ans), cet essai randomisé compare l'intérêt, pour améliorer la qualité de leur sommeil, d'interventions à base d'acupunture (électro-acupuncture et acupuncture auriculaire) et d'interventions utilisant des soins standards
Effect of acupuncture versus usual care on sleep quality in cancer survivors with chronic pain: Secondary analysis of a randomized clinical trial
Yang, Mingxiao ; Baser, Raymond E. ; Liou, Kevin T. ; Li, Susan Q. ; Piulson, Lauren ; Panageas, Katherine S. ; Mao, Jun J.
Background : Chronic pain negatively affects sleep; it is unclear whether pain relief from acupuncture contributes to sleep quality improvements in cancer survivors. This study aimed to evaluate the effect of acupuncture versus usual care on sleep quality among cancer survivors with comorbid sleep disturbance and chronic musculoskeletal pain. Methods : Sleep outcome data from the Personalized Electroacupuncture Versus Auricular Acupuncture Comparative Effectiveness (PEACE) randomized clinical [...]
Mené à partir de données portant sur 169 patients atteints d'un lymphome hodgkinien de stade précoce et inclus dans un essai randomisé évaluant l'efficacité d'une chimiothérapie de type ABVD (doxorubicine, bléomycine, vinblastine et dacarbazine), cette étude analyse l'évolution de leur qualité de vie depuis le diagnostic jusqu'à 10 ans après la fin des traitements
Health-related quality of life in early-stage Hodgkin lymphoma: a longitudinal analysis of the ABVD arm in the randomized controlled trial HD.6
Mené à partir de données portant sur 169 patients atteints d'un lymphome hodgkinien de stade précoce et inclus dans un essai randomisé évaluant l'efficacité d'une chimiothérapie de type ABVD (doxorubicine, bléomycine, vinblastine et dacarbazine), cette étude analyse l'évolution de leur qualité de vie depuis le diagnostic jusqu'à 10 ans après la fin des traitements
Health-related quality of life in early-stage Hodgkin lymphoma: a longitudinal analysis of the ABVD arm in the randomized controlled trial HD.6
Mian, Hira ; Ringash, Jolie ; Meyer, Ralph ; Hay, Annette E. ; Shepherd, Lois ; Djurfeldt, Marina ; Winter, Jane N. ; Sussman, Jonathan ; Pater, Joseph ; Chen, Bingshu E. ; Prica, Anca
Early-stage Hodgkin lymphoma has become one of the most curable hematologic malignancies. Depending upon the disease location, possible toxicities, and patient preference, chemotherapy alone with ABVD remains an accepted treatment modality for this disease. There remains a paucity of data regarding the longitudinal trajectory of health-related quality of life (HRQoL) in patients treated for HL. The impact of disease and treatment on HRQoL is increasingly important to understand as the number of [...]
Observation (4)
Menée au Canada à partir de données portant sur des patientes atteintes d'un cancer diagnostiqué pendant leur grossesse ou durant l'année suivant la naissance de leur enfant, cette étude de cohorte rétrospective analyse la survie globale à 1 et 5 ans selon la localisation de la maladie
Long-term Mortality in Individuals Diagnosed With Cancer During Pregnancy or Postpartum
Menée au Canada à partir de données portant sur des patientes atteintes d'un cancer diagnostiqué pendant leur grossesse ou durant l'année suivant la naissance de leur enfant, cette étude de cohorte rétrospective analyse la survie globale à 1 et 5 ans selon la localisation de la maladie
Long-term Mortality in Individuals Diagnosed With Cancer During Pregnancy or Postpartum
Cairncross, Zoe F. ; Shack, Lorraine ; Nelson, Gregg ; Friedenreich, Christine M. ; Ray, Joel ; Fell, Deshayne B. ; Lisonkova, Sarka ; Bhatti, Parveen ; Sikdar, Khokan ; McMorris, Carly ; Metcalfe, Amy
Importance : Outcomes among patients with pregnancy-associated cancers (diagnosed during pregnancy or 1-year postpartum) other than breast cancer have received relatively little research attention. High-quality data from additional cancer sites are needed to inform the care of this unique group of patients. Objective : To assess mortality and survival in premenopausal women with pregnancy-associated cancers, with a particular focus on cancers other than those of the breast. Design, Setting, and [...]
Menée aux Etats-Unis et au Canada à partir de données 1970-1999 portant sur 34 230 patients ayant survécu au moins 5 ans à un cancer diagnostiqué avant l'âge de 21 ans, cette étude de cohorte rétrospective analyse les causes de mortalité excessive tardive (décès ayant lieu au moins 40 ans après le diagnostic) et notamment les causes liées à des facteurs comportementaux
Specific causes of excess late mortality and association with modifiable risk factors among survivors of childhood cancer: a report from the Childh...
Menée aux Etats-Unis et au Canada à partir de données 1970-1999 portant sur 34 230 patients ayant survécu au moins 5 ans à un cancer diagnostiqué avant l'âge de 21 ans, cette étude de cohorte rétrospective analyse les causes de mortalité excessive tardive (décès ayant lieu au moins 40 ans après le diagnostic) et notamment les causes liées à des facteurs comportementaux
Specific causes of excess late mortality and association with modifiable risk factors among survivors of childhood cancer: a report from the Childhood Cancer Survivor Study cohort
Dixon, Stephanie B. ; Liu, Qi ; Chow, Eric J. ; Oeffinger, Kevin C. ; Nathan, Paul C. ; Howell, Rebecca M. ; Leisenring, Wendy M. ; Ehrhardt, Matthew J. ; Ness, Kirsten K. ; Krull, Kevin R. ; Mertens, Ann C. ; Hudson, Melissa M. ; Robison, Leslie L. ; Yasui, Yutaka ; Armstrong, Gregory T.
Background: 5-year survival after childhood cancer does not fully describe life-years lost due to childhood cancer because there are a large number of deaths occurring beyond 5-years (late mortality) related to cancer and cancer treatment. Specific causes of health-related (non-recurrence, non-external) late mortality and risk reduction through modifiable lifestyle and cardiovascular risk factors are not well described. Through using a well-characterised cohort of 5-year survivors of the most [...]
Menée aux Etats-Unis, cette étude analyse les facteurs associés à une utilisation de cannabis, thérapeutique ou non, chez des patients ayant survécu à un cancer
Cannabis use among cancer survivors in 22 states: Results from the Behavioral Risk Factor Surveillance System, 2020
Menée aux Etats-Unis, cette étude analyse les facteurs associés à une utilisation de cannabis, thérapeutique ou non, chez des patients ayant survécu à un cancer
Cannabis use among cancer survivors in 22 states: Results from the Behavioral Risk Factor Surveillance System, 2020
Sedani, Ami E. ; Campbell, Janis E. ; Beebe, Laura A.
Background: This study identified factors associated with recent cannabis use and cannabis use for medical purposes among cancer survivors relative to individuals without a history of cancer. Methods: Data from the Behavioral Risk Factor Surveillance System were analyzed for the 22 states completing the optional cannabis module in 2020. Weighted multiple logistic regression was performed to explore variables associated with past 30-day cannabis use and cannabis use for medical purposes, [...]
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The effect of COVID-19 on surgical management of skin cancers of the head, face and neck in elderly patients
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The effect of COVID-19 on surgical management of skin cancers of the head, face and neck in elderly patients
Borg, Tiffanie-Marie ; Eisold, Jessica ; Miyanjo, Yusuf ; Pappa, Elena
Background: The Corona Virus (COVID-19) has had a profound impact on healthcare systems worldwide, with interruptions to medical practices including the delivery of cancer treatment. Skin cancer is one of the leading causes of malignancy worldwide, with later stages of disease correlating to poorer prognosis. Immunocompromized and elderly patients represent populations that are at higher risk for adverse outcomes related to skin cancer, treatment delay and COVID-19 infection. Methodology: [...]
Anti-CD20 antibodies and bendamustine attenuate humoral immunity to COVID-19 vaccination in patients with B-cell non-Hodgkin lymphoma
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Anti-CD20 antibodies and bendamustine attenuate humoral immunity to COVID-19 vaccination in patients with B-cell non-Hodgkin lymphoma
Ishio, Takashi ; Tsukamoto, Shihori ; Yokoyama, Emi ; Izumiyama, Koh ; Saito, Makoto ; Muraki, Haruna ; Kobayashi, Mirei ; Mori, Akio ; Morioka, Masanobu ; Kondo, Takeshi
Serologic responses of COVID-19 vaccine are impaired in patients with B-cell lymphoma, especially those who had recently been treated with anti-CD20 monoclonal antibodies. However, it is still unclear whether those patients develop an immune response following vaccination. We investigated the efficacy of vaccination against SARS-CoV-2 in 171 patients with B-cell non-Hodgkin lymphoma (B-NHL) who received two doses of an mRNA-based COVID-19 vaccine and we compared the efficacy of vaccination to [...]
Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Robust SARS-CoV-2 T cell responses with common TCRαβ motifs toward COVID-19 vaccines in patients with hematological malignancy impacting B cells
Nguyen, Thi H. O. ; Rowntree, Louise C. ; Allen, Lilith F. ; Chua, Brendon Y. ; Kedzierski, Lukasz ; Lim, Chhay ; Lasica, Masa ; Tennakoon, G. Surekha ; Saunders, Natalie R. ; Crane, Megan ; Chee, Lynette ; Seymour, John F. ; Anderson, Mary Ann ; Whitechurch, Ashley ; Clemens, E. Bridie ; Zhang, Wuji ; Chang, So Young ; Habel, Jennifer R. ; Jia, Xiaoxiao ; McQuilten, Hayley A. ; Minervina, Anastasia A. ; Pogorelyy, Mikhail V. ; Chaurasia, Priyanka ; Petersen, Jan ; Menon, Tejas ; Hensen, Luca ; Neil, Jessica A. ; Mordant, Francesca L. ; Tan, Hyon-Xhi ; Cabug, Aira F. ; Wheatley, Adam K. ; Kent, Stephen J. ; Subbarao, Kanta ; Karapanagiotidis, Theo ; Huang, Han ; Vo, Lynn K. ; Cain, Natalie L. ; Nicholson, Suellen ; Krammer, Florian ; Gibney, Grace ; James, Fiona ; Trevillyan, Janine M. ; Trubiano, Jason A. ; Mitchell, Jeni ; Christensen, Britt ; Bond, Katherine A. ; Williamson, Deborah A. ; Rossjohn, Jamie ; Crawford, Jeremy Chase ; Thomas, Paul G. ; Thursky, Karin A. ; Slavin, Monica A. ; Tam, Constantine S. ; Teh, Benjamin W. ; Kedzierska, Katherine
Immunocompromised hematology patients are vulnerable to severe COVID-19 and respond poorly to vaccination. Relative deficits in immunity are, however, unclear, especially after 3 vaccine doses. We evaluated immune responses in hematology patients across three COVID-19 vaccination doses. Seropositivity was low after a first dose of BNT162b2 and ChAdOx1 (
COVID-19 vaccine uptake trends in SARS-CoV-2 previously infected cancer patients
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
COVID-19 vaccine uptake trends in SARS-CoV-2 previously infected cancer patients
Shahid, Zainab ; Patrick, Alicia L. ; Wallander, Michelle L. ; Donahue, Erin E. ; Trufan, Sally J. ; Tan, Antoinette R. ; Hwang, Jimmy J. ; Burgess, Earle F. ; Ragon, Brittany ; Ghosh, Nilanjan ; Grunwald, Michael R. ; Voorhees, Peter M. ; Copelan, Edward A. ; Raghavan, Derek
Purpose Cancer patients are at high risk of developing severe illness from SARS-CoV-2 infection, but risk is lowered with receipt of COVID-19 vaccine. COVID-19 vaccination uptake among previously infected cancer patients may be influenced by an assumption of natural immunity, predicted weak immune response, or concerns about vaccine safety. The objective of this study was to evaluate COVID-19 vaccine uptake trends in cancer patients previously infected with SARS-CoV-2. Materials and Methods [...]
Risk factors and actionable molecular signatures in COVID-19-associated lung adenocarcinoma and lung squamous cell carcinoma patients
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Risk factors and actionable molecular signatures in COVID-19-associated lung adenocarcinoma and lung squamous cell carcinoma patients
Ullah, Md Asad ; Alam, Sayka ; Moin, Abu Tayab ; Ahamed, Tanvir ; Shohael, Abdullah Mohammad
The molecular mechanism of the pathological impact of COVID-19 in lung cancer patients remains poorly understood to date. In this study, we used differential gene expression pattern analysis to try to figure out the possible disease mechanism of COVID-19 and its associated risk factors in patients with the two most common types of non-small-cell lung cancer, namely, lung adenocarcinoma and lung squamous cell carcinoma. We also used network-based approaches to identify potential diagnostic and [...]
Association of the COVID-19 Pandemic and Changes in Patterns of Cancer-Related Mortality in the United States
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Association of the COVID-19 Pandemic and Changes in Patterns of Cancer-Related Mortality in the United States
Jingxuan Zhao ; Xuesong Han ; Kimberly D. Miller ; Zhiyuan Zheng ; Leticia Nogueira ; Farhad Islami ; Ahmedin Jemal ; K. Robin Yabroff
PURPOSE: This study examined changes in patterns of cancer-related deaths during the first year of the coronavirus disease 2019 pandemic in the United States. METHODS: We identified cancer-related deaths, defined as deaths attributable to cancer as the primary cause (underlying cause) or deaths with cancer documented as one of the multiple contributing factors (contributing cause) from the Multiple Cause of Death database (2015-2020). We compared age-standardized cancer-related annual and [...]
Approches psycho-sociales (1)
Menée aux Etats-Unis à partir de données portant sur 103 aidants d'un conjoint atteint d'un cancer et sur 515 témoins (aidants d'un conjoint atteint d'une autre pathologie), cette étude analyse la situation professionnelle des aidants et leurs difficultés psychiques associées
Working, Low Income, and Cancer Caregiving: Financial and Mental Health Impacts
Menée aux Etats-Unis à partir de données portant sur 103 aidants d'un conjoint atteint d'un cancer et sur 515 témoins (aidants d'un conjoint atteint d'une autre pathologie), cette étude analyse la situation professionnelle des aidants et leurs difficultés psychiques associées
Working, Low Income, and Cancer Caregiving: Financial and Mental Health Impacts
Cathy J. Bradley ; Sara Kitchen ; Kelsey M. Owsley
PURPOSE: Approximately 6 million people provide caregiving to people diagnosed with cancer. Many must remain employed to support their household and to have access to health insurance. It is unknown if caregiving for a spouse diagnosed with cancer is associated with greater financial and mental stress relative to providing care for a spouse with different conditions. METHODS: Health and Retirement Study (2002-2020) data were used to compare employed caregivers, younger than age 65 years, caring [...]
Analyses économiques et systèmes de soins (1)
Menée aux Etats-Unis par enquête auprès de 307 dyades constituées de patients ayant survécu à un cancer colorectal et de leurs conjoints, cette étude analyse l'association entre des difficultés financières et la qualité de vie des partenaires de vie
Financial Toxicity and Its Association With Health-Related Quality of Life Among Partners of Colorectal Cancer Survivors
Menée aux Etats-Unis par enquête auprès de 307 dyades constituées de patients ayant survécu à un cancer colorectal et de leurs conjoints, cette étude analyse l'association entre des difficultés financières et la qualité de vie des partenaires de vie
Financial Toxicity and Its Association With Health-Related Quality of Life Among Partners of Colorectal Cancer Survivors
Ghazal, Lauren V. ; Abrahamse, Paul ; Ward, Kevin C. ; Morris, Arden M. ; Hawley, Sarah T. ; Veenstra, Christine M.
Importance : Partners of colorectal cancer (CRC) survivors play a critical role in diagnosis, treatment, and survivorship. While financial toxicity (FT) is well documented among patients with CRC, little is known about long-term FT and its association with health-related quality of life (HRQoL) among their partners. Objective : To understand long-term FT and its association with HRQoL among partners of CRC survivors. Design, Setting, and Participants : This survey study incorporating a [...]
Financial Toxicity Among Caregivers of Patients With Cancer—An Increasing Problem Requiring Novel Solutions
Menée aux Etats-Unis par enquête auprès de 307 dyades constituées de patients ayant survécu à un cancer colorectal et de leurs conjoints, cette étude analyse l'association entre des difficultés financières et la qualité de vie des partenaires de vie
Financial Toxicity Among Caregivers of Patients With Cancer—An Increasing Problem Requiring Novel Solutions
Peddireddi, Ayush ; Aviki, Emeline M.
Advancements in modern clinical oncology have led to more advanced and personalized treatments, which in turn have led to higher costs that can have deleterious consequences. This unintended yet important aspect of cancer care, known as financial toxicity, has been associated with downstream ramifications, such as bankruptcy and early mortality.1 While many studies have looked at the differences in financial toxicity across demographic groups and cancer types, these analyses have been primarily [...]
Soins palliatifs (1)
Menée au Canada à partir de données portant sur 40 patients atteints d'un cancer du pancréas de stade avancé (âge médian : 70 ans), cette étude prospective analyse l'effet, sur leur qualité de vie, de soins palliatifs précoces
The impact of early palliative care on the quality of life of patients with advanced pancreatic cancer: The IMPERATIVE case-crossover study
Menée au Canada à partir de données portant sur 40 patients atteints d'un cancer du pancréas de stade avancé (âge médian : 70 ans), cette étude prospective analyse l'effet, sur leur qualité de vie, de soins palliatifs précoces
The impact of early palliative care on the quality of life of patients with advanced pancreatic cancer: The IMPERATIVE case-crossover study
Kim, Christina A. ; Lelond, Stephanie ; Daeninck, Paul J. ; Rabbani, Rasheda ; Lix, Lisa ; McClement, Susan ; Chochinov, Harvey Max ; Goldenberg, Benjamin A.
Purpose: Pancreatic cancer is a lethal disease. Many patients experience a heavy burden of cancer-associated symptoms and poor quality of life (QOL). Early palliative care alongside standard oncologic care results in improved QOL and survival in some cancer types. The benefit in advanced pancreatic cancer (APC) is not fully quantified. Methods: In this prospective case-crossover study, patients ≥ 18 years old with APC were recruited from ambulatory clinics at a tertiary cancer center. Patients [...]
Ethique (1)
Cette étude présente les conseils éthiques de l'"Americain Society of Clinical Oncology" pour les cancérologues prenant en charge des patientes enceintes atteintes d'un cancer dans les Etats où l'accès à l'avortement est illégal ou limité
ASCO Ethical Guidance for the US Oncology Community Where Reproductive Health Care Is Limited by Law
Cette étude présente les conseils éthiques de l'"Americain Society of Clinical Oncology" pour les cancérologues prenant en charge des patientes enceintes atteintes d'un cancer dans les Etats où l'accès à l'avortement est illégal ou limité
ASCO Ethical Guidance for the US Oncology Community Where Reproductive Health Care Is Limited by Law
Spence, Rebecca A. ; Hinyard, Leslie J. ; Jagsi, Reshma ; Jimenez, Rachel B. ; Lopez, Ana Maria ; Chavez-MacGregor, Mariana ; Spector-Bagdady, Kayte ; Rosenberg, Abby R.
The decision in Dobbs v Jackson Women's Health Organization overturned federal protections for abortion rights, making way for states to enact abortion bans with or without exceptions for the health or life of the pregnant patient. Patient care across many areas of medicine including oncology continues to be affected. Although the change in the legal landscape is widely felt, the core ethical considerations for physicians do not change because of restrictions on the practice of medicine. ASCO [...]
Ressources et infrastructures (Lutte contre les cancers) (2)
A partir d'une revue systématique de la littérature publiée jusqu'en février 2022 (87 articles), cette étude identifie, chez des patients ayant survécu à un cancer, les facteurs entravant leur participation à des essais cliniques évaluant des interventions à base d'exercices physiques puis analyse les stratégies de recrutement
Recruitment rates and strategies in exercise trials in cancer survivorship: a systematic review
A partir d'une revue systématique de la littérature publiée jusqu'en février 2022 (87 articles), cette étude identifie, chez des patients ayant survécu à un cancer, les facteurs entravant leur participation à des essais cliniques évaluant des interventions à base d'exercices physiques puis analyse les stratégies de recrutement
Recruitment rates and strategies in exercise trials in cancer survivorship: a systematic review
Reynolds, Sophie A. ; O’Connor, Louise ; McGee, Anna ; Kilcoyne, Anna Quinn ; Connolly, Archie ; Mockler, David ; Guinan, Emer ; O’Neill, Linda
Purpose: Despite clear evidence-based supporting a benefit to exercise on physical and psychological metrics in patients with cancer, recruitment to exercise trials amongst cancer survivors is suboptimal. We explore current recruitment rates, strategies, and common barriers to participation in exercise oncology trials in cancer survivorship. Methods: A systematic review was conducted using a pre-defined search strategy in EMBASE, CINAHL, Medline, Cochrane Library, and Web of Science. The search [...]
A partir d'une revue systématique de la littérature publiée jusqu'en mai 2022 (31 études), cette étude analyse l'utilisation de l'indice de vulnérabilité sociale, un outil développé par les "Centers for Disease Control and Prevention" dans les études évaluant les disparités en cancérologie
The social vulnerability index as a risk stratification tool for health disparity research in cancer patients: a scoping review
A partir d'une revue systématique de la littérature publiée jusqu'en mai 2022 (31 études), cette étude analyse l'utilisation de l'indice de vulnérabilité sociale, un outil développé par les "Centers for Disease Control and Prevention" dans les études évaluant les disparités en cancérologie
The social vulnerability index as a risk stratification tool for health disparity research in cancer patients: a scoping review
Tran, Tiffaney ; Rousseau, Morgan A. ; Farris, David P. ; Bauer, Cici ; Nelson, Kelly C. ; Doan, Hung Q.
Purpose: The social vulnerability index (SVI), developed by the Centers for Disease Control and Prevention, is a novel composite measure encompassing multiple variables that correspond to key social determinants of health. The objective of this review was to investigate innovative applications of the SVI to oncology research and to employ the framework of the cancer care continuum to elucidate further research opportunities. Methods: A systematic search for relevant articles was performed in [...]
