A partir d'une revue systématique de la littérature (18 articles), cette étude analyse l'utilisation du cannabis thérapeutique chez les patients atteints d'un cancer

Pharmacological evidence of medicinal cannabis in oncology: a systematic review

Brown, Danielle ; Watson, Michael ; Schloss, Janet

Purpose : This systematic literature review examines research into the use of medicinal cannabis in cancer management. The aim was to identify the gaps in knowledge on the dose, dosing schedule and absorption of the administration routes of medicinal cannabis use in oncology. Methods : A comprehensive search of the literature was conducted across six databases to identify original data reporting the pharmacology of medicinal cannabis in oncology. Results : Eighteen articles were selected for [...]

Menée au Canada par enquête auprès de 204 professionnels de santé, cette étude analyse leurs connaissances et leurs opinions concernant la musicothérapie pour prendre en charge ou soulager les symptômes physiques et psychiques chez des patients atteints d'un cancer

A survey of oncology healthcare professionals’ knowledge and attitudes toward the use of music as a therapeutic tool in healthcare

Esplen, Mary Jane ; Foster, Bev ; Pearson, Sarah ; Wong, Jiahui ; Mackinnon, Chelsea ; Shamsudeen, Isabel ; Cecchin, Katharine

Background : Music as a therapeutic tool, defined as “music care,” can help manage physical and psychological symptoms in individuals with cancer. There is further need to understand interest level and the potential role of music care among health professionals working in the field of oncology. Purpose : To investigate knowledge of and attitudes toward the use of music as a therapeutic tool in cancer and palliative care, as well as to identify barriers associated with learning to use music in [...]

Menée en Allemagne à partir de données portant sur 911 patients ayant survécu entre 5 et 15 ans à un cancer localisé de la prostate, cette étude analyse la qualité de vie à long terme en fonction des différents traitements reçus (thérapie anti-androgénique, prostatectomie radicale, radiothérapie, utilisées seules ou en combinaison)

Health-related quality of life in long-term survivors with localised prostate cancer by therapy—Results from a population-based study

Adam, Salome ; Koch-Gallenkamp, Lena ; Bertram, Heike ; Eberle, Andrea ; Holleczek, Bernd ; Pritzkuleit, Ron ; Waldeyer-Sauerland, Mechthild ; Waldmann, Annika ; Zeissig, Sylke Ruth ; Rohrmann, Sabine ; Brenner, Hermann ; Arndt, Volker

Objective : Several therapies for localised prostate cancer (PC) are available; all yield similar survival rates. However, each therapy has significant side effects that can influence patients' health-related quality of life (HRQoL) in the long run. Methods : The study sample included 911 survivors with localised PC, 5–15 years post‐diagnosis who were identified from the population‐based CAESAR + study in Germany. HRQoL was assessed using the EORTC QLQ‐C30 and EORTC QLQ‐PR25 questionnaires. The [...]

Menée aux Etats-Unis à partir de données portant sur 14 453 personnes infectées par le VIH et sur 6 368 126 témoins, cette étude analyse l'impact d'une infection par le VIH sur le stade du cancer au moment du diagnostic et sur la mortalité

Advanced stage at diagnosis and elevated mortality among US patients with cancer infected with HIV in the National Cancer Data Base

Coghill, Anna E. ; Han, Xuesong ; Suneja, Gita ; Lin, Chun Chieh ; Jemal, Ahmedin ; Shiels, Meredith S.

Background : People living with HIV (PLWH) are at an increased risk of developing several cancers, but to the authors’ knowledge less is known regarding how HIV impacts the rate of progression to advanced cancer or death. Methods : The authors compared stage of disease at the time of presentation and mortality after diagnosis between 14,453 PLWH and 6,368,126 HIV-uninfected patients diagnosed with cancers of the oral cavity, stomach, colorectum, anus, liver, pancreas, lung, female breast, [...]

Menée en France à partir de données portant sur 2 973 patients atteints d'un cancer diagnostiqué en 2015, cette étude analyse la part des cancers attribuable à une activité physique insuffisante

Cancers in France in 2015 attributable to insufficient physical activity

Touillaud, Marina ; Arnold, Melina ; Dossus, Laure ; Freisling, Heinz ; Bray, Freddie ; Margaritis, Irène ; Deschamps, Valérie ; Soerjomataram, Isabelle

Introduction : Insufficient physical activity is a known risk factor for various co-morbidities, including cancer. Globally, its prevalence has increased markedly over the past decades. The aim of this study was to estimate the proportion and number of cancers that were attributable to insufficient physical activity in France in 2015. Methods : Population attributable fractions (PAFs) and numbers of cancer cases attributable to insufficient physical activity (<30 min daily of [...]

Menée au Japon à partir de données portant sur 198 patients atteints d'un cancer du poumon et présentant des métastases osseuses, cette étude rétrospective évalue l'association entre la masse des muscles paravertébraux et la survie globale

Low paravertebral muscle mass in patients with bone metastases from lung cancer is associated with poor prognosis

Dohzono, Sho ; Sasaoka, Ryuichi ; Takamatsu, Kiyohito ; Hoshino, Masatoshi ; Nakamura, Hiroaki

Purpose : Low skeletal muscle mass has been associated with poor prognosis in patients with advanced lung cancer. However, little is known about the relationship between skeletal muscle mass and overall survival in patients with bone metastases from lung cancer. The objective of the present study was to evaluate the prognostic value of low trunk muscle mass in predicting overall survival in these patients. Methods : The data from 198 patients who were diagnosed with bone metastases from lung [...]

Menée au Danemark à partir de données portant sur 25 463 hommes âgés de 50 à 64 ans sans antécédent de cancer et sur 1 546 patients atteints d'un cancer de la prostate ayant reçu un traitement de première ligne, cette étude analyse, chez ces deux populations, les facteurs associés au risque d'événements indésirables cardiovasculaires (durée de suivi : 18 ans)

Risk of cardiovascular events in men treated for prostate cancer compared with prostate cancer-free men

Moustsen, Ida Rask ; Larsen, Signe Benzon ; Duun-Henriksen, Anne Katrine ; Tjønneland, Anne ; Kjær, Susanne K. ; Brasso, Klaus ; Johansen, Christoffer ; Dalton, Susanne Oksbjerg

Background : The effect of lifestyle, anthropometry and cardiovascular risk factors on cardiovascular disease in men with prostate cancer (PCa) remains unclear. Methods : Using a population-based cohort of 25,436 Danish, cancer-free men aged 50–64 years, we obtained information on self-reported pre-cancer lifestyle, objectively measured anthropometry and cardiovascular risk factors, and linked them to national health registers for information on major cardiovascular outcomes. We assessed hazard [...]

A partir d'une revue systématique de la littérature (26 articles), cette étude analyse, en fonction du lieu d'habitation (zone urbaine ou rurale), le stade au diagnostic et la survie chez des patients atteints d'un cancer colorectal et vivant en Australie

Geographic variations in stage at diagnosis and survival for colorectal cancer in Australia: A systematic review

Crawford-Williams, Fiona ; March, Sonja ; Goodwin, Belinda C. ; Ireland, Michael J. ; Chambers, Suzanne K. ; Aitken, Joanne F. ; Dunn, Jeff

Introduction : Australia has one of the highest incidence rates of colorectal cancer (CRC) in the world. Residents in rural areas of Australia experience disadvantage in health care and outcomes. This review investigates whether patients with CRC in rural areas demonstrate poorer survival and more advanced stages of disease at diagnosis. Methods : Systematic review of peer-reviewed articles and grey literature. Studies were included if they provided data on survival or stage of disease at [...]

Menée aux Etats-Unis à partir de données portant sur 49 143 patients atteints d'un cancer colorectal ou pulmonaire (âge moyen : 54,8 ans), cette étude de cohorte rétrospective évalue l'association entre la santé cardiorespiratoire et le risque de développer la maladie (durée médiane de suivi : 7,7 ans)

Cardiorespiratory fitness and incident lung and colorectal cancer in men and women: Results from the Henry Ford Exercise Testing (FIT) cohort

Marshall, Catherine Handy ; Al-Mallah, Mouaz H. ; Dardari, Zeina ; Brawner, Clinton A. ; Lamerato, Lois E. ; Keteyian, Steven J. ; Ehrman, Jonathan K. ; Visvanathan, Kala ; Blaha, Michael J.

Background : To the authors’ knowledge, the relationship between cardiorespiratory fitness (CRF) and lung and colorectal cancer outcomes is not well established. Methods : A retrospective cohort study was performed of 49,143 consecutive patients who underwent clinician‐referred exercise stress testing from 1991 through 2009. The patients ranged in age from 40 to 70 years, were without cancer, and were treated within the Henry Ford Health System in Detroit, Michigan. CRF, measured in metabolic [...]

Menée à partir de données portant sur 260 enfants atteints d'une tumeur cérébrale embryonnaire (âge moyen : 9,15 ans), cette étude analyse l'état de leurs fonctions neurocognitives (capacité de lecture, compréhension, mémoire,...) en lien avec l'ototoxicité des traitements anticancéreux

Cognitive Implications of Ototoxicity in Pediatric Patients With Embryonal Brain Tumors

Traci W. Olivier ; Johnnie K. Bass ; Jason M. Ashford ; Rebecca Beaulieu ; Sarah M. Scott ; Jane E. Schreiber ; Shawna Palmer ; Donald J. Mabbott ; Michelle A. Swain ; Melanie Bonner ; Robyn Boyle ; Mary Lynn Chapeiski ; Karen D. Evankovich ; Carol L. Armstrong ; Sarah J. Knight ; Shengjie Wu ; Arzu Onar-Thomas ; Amar Gajjar ; Heather M. Conklin

PURPOSE : Sensorineural hearing loss (SNHL) is associated with intellectual and academic declines in children treated for embryonal brain tumors. This study expands upon existing research by examining core neurocognitive processes that may result in reading difficulties in children with treatment-related ototoxicity. PATIENTS AND METHODS : Prospectively gathered, serial, neuropsychological and audiology data for 260 children and young adults age 3 to 21 years (mean, 9.15 years) enrolled in a [...]

A partir d'une revue systématique de la littérature publiée jusqu'en 2018 (41 articles), cette étude analyse l'intérêt des outils permettant de mesurer les difficultés financières rencontrées par les patients atteints d'un cancer

Methods for measuring financial toxicity after cancer diagnosis and treatment: a systematic review and its implications

Witte, J ; Mehlis, K ; Surmann, B ; Lingnau, R ; Damm, O ; Greiner, W ; Winkler, E C

Background : Patients experiencing financial distress as a side effect of cancer are not only reported in the US, but also in third-party payer healthcare systems in Europe. Since validated survey instruments are a prerequisite for robust and comparable results, we aimed to compile and classify available instruments to enable both a better understanding of the underlying construct of financial toxicity and to facilitate further studies that are adjustable to various healthcare systems. [...]