Cette étude analyse l'association entre une ingestion d'amiante contenue dans les boissons alcoolisées, en particulier dans la bière, jusqu'à la fin des années 1970 et le risque d'adénocarcinome œsophagien

Ingested asbestos in filtered beer, in addition to occupational exposure, as a causative factor in oesophageal adenocarcinoma

Fitzgerald, Rebecca C. ; Rhodes, Jonathan M.

Oesophageal adenocarcinoma has become much more common over the past 50 years, particularly in Britain, with an unexplained male to female ratio of > 4:1. Given the use of asbestos filtration in commercial brewing and reports of its unregulated use in British public houses in the 1970’s to clear draught beer “slops”, we have assessed the hypothesis that ingested asbestos could be a causative factor for this increased incidence. Importantly, occupational asbestos exposure increases the risk of [...]

A partir d'une revue systématique de la littérature (21 études, environ 900 000 patientes), cette méta-analyse évalue l'association entre une alimentation riche en graisses et le risque de cancer de l'ovaire, selon la quantité et le type de graisses ingérées

Dietary Fat Intake and Risk of Ovarian Cancer: A Systematic Review and Dose–Response Meta-Analysis of Observational Studies

Sadeghi, Alireza ; Shab-Bidar, Sakineh ; Parohan, Mohammad ; Djafarian, Kurosh

Observational studies have reported controversial evidence of the association between dietary fat intake and ovarian cancer. This dose?response meta-analysis aimed to clarify quantitatively the association between dietary fat intake and ovarian cancer. The linear and non-linear relationships between fat intake and risk of ovarian cancer were investigated. Heterogeneity, sensitivity analysis, and publication bias were also assessed. Overall, 21 studies involved approximately 900,000 subjects [...]

Menée dans 5 pays (Australie, Danemark, Israël, Norvège et Royaume-Uni) à partir de données portant sur 329 658 participants, cette étude de cohorte évalue l'association entre une exposition d'origine professionnelle des parents à des pesticides, des animaux ou des poussières organiques et le risque, chez l'enfant, de développer une leucémie ou une tumeur du système nerveux central

Parental Occupational Exposure to Pesticides, Animals, and Organic Dust and Risk of Childhood Leukemia and Central Nervous System Tumors: Findings from the International Childhood Cancer Cohort Consortium (I4C)

Patel, Deven M. ; Jones, Rena R. ; Booth, Benjamin J. ; Olsson, Ann C. ; Kromhout, Hans ; Straif, Kurt ; Vermeulen, Roel ; Tikellis, Gabriella ; Paltiel, Ora ; Golding, Jean ; Northstone, Kate ; Stoltenberg, Camilla ; Håberg, Siri E. ; Schüz, Joachim ; Friesen, Melissa C. ; Ponsonby, Anne-Louise ; Lemeshow, Stanley ; Linet, Martha S. ; Magnus, Per ; Olsen, Jørn ; Olsen, Sjurdur F. ; Dwyer, Terence ; Stayner, Leslie T. ; Ward, Mary H. ; on behalf of the International Childhood Cancer Cohort Consortium

Parental occupational exposure to pesticides, animals, and organic dust have been associated with an increased risk of childhood cancer based mostly on case-control studies. We prospectively evaluated parental occupational exposures and risk of childhood leukemia and central nervous system (CNS) tumors in the International Childhood Cancer Cohort Consortium. We pooled data on 329,658 participants from birth cohorts in five countries (Australia, Denmark, Israel, Norway, and United Kingdom). [...]

Menée en Suède à partir de données portant sur 111 198 individus suivis entre 1985 et 2017, cette étude analyse l'association entre un prédiabète ou un diabète et le risque d'adénocarcinome de l'estomac

Prediabetes and diabetes in relation to risk of gastric adenocarcinoma

Zheng, Jiaojiao ; Rutegård, Martin ; Santoni, Giola ; Wallner, Bengt ; Johansson, Ingegerd ; Sund, Malin ; Xie, Shao-Hua ; Lagergren, Jesper

Background : Whether prediabetes or diabetes increases the risk of gastric adenocarcinoma is not clear. Methods : This cohort study included 111,198 participants in the Northern Swedish Health and Disease Study. The participants were followed up from November 1985 to April 2017. The exposure to prediabetes or diabetes was assessed by oral glucose tolerance tests and self-reports. The incidence of the outcome gastric adenocarcinoma was identified from the Swedish Cancer Registry. Multivariable [...]

A partir des données de la cohorte européenne EPIC portant sur 476 160 participants, cette étude analyse l'association entre des facteurs anthopométriques et reproductifs et le risque de cancer de l'œsophage ou de l'estomac par sous-type (durée moyenne de suivi : 14 ans)

Anthropometric and reproductive factors and risk of esophageal and gastric cancer by subtype and subsite: results from the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Sanikini, Harinakshi ; Muller, David C ; Sophiea, Marisa ; Rinaldi, Sabina ; Agudo, Antonio ; Duell, Eric J ; Weiderpass, Elisabete ; Overvad, Kim ; Tjønneland, Anne ; Halkjær, Jytte ; Boutron-Ruault, Marie-Christine ; Carbonnel, Franck ; Cervenka, Iris ; Boeing, Heiner ; Kaaks, Rudolf ; Kühn, Tilman ; Trichopoulou, Antonia ; Martimianaki, Georgia ; Karakatsani, Anna ; Pala, Valeria ; Palli, Domenico ; Mattiello, Amalia ; Tumino, Rosario ; Sacerdote, Carlotta ; Skeie, Guri ; Rylander, Charlotta ; López, María Dolores Chirlaque ; Sánchez, María-José ; Ardanaz, Eva ; Regner, Sara ; Stocks, Tanja ; Bueno-de-Mesquita, Bas ; Vermeulen, Roel C.H. ; Aune, Dagfinn ; Tong, Tammy Y.N. ; Kliemann, Nathalie ; Murphy, Neil ; Chadeau-Hyam, Marc ; Gunter, Marc J ; Cross, Amanda J

Obesity has been associated with upper gastrointestinal cancers; however, there are limited prospective data on associations by subtype/subsite. Obesity can impact hormonal factors, which have been hypothesized to play a role in these cancers. We investigated anthropometric and reproductive factors in relation to esophageal and gastric cancer by subtype and subsite for 476,160 participants from the European Prospective Investigation into Cancer and Nutrition cohort. Multivariable hazard ratios [...]

Menée à partir des données du registre suédois des cancers portant sur 14 393 patients atteints d'un lymphome non hodgkinien entre 1958 et 2015, cette étude évalue l'association entre des antécédents familiaux de cancer et le risque de développer un second cancer primitif, puis analyse l'impact de ce second cancer sur la survie (durée de suivi : 25 ans)

Second primary cancers in non-Hodgkin lymphoma: family history and survival

Chattopadhyay, Subhayan ; Zheng, Guoqiao ; Sud, Amit ; Sundquist, Kristina ; Sundquist, Jan ; Försti, Asta ; Houlston, Richard ; Hemminki, Akseli ; Hemminki, Kari

Second primary cancers (SPCs) account for an increasing proportion of all cancer diagnoses and family history of cancer may be a risk factor for SPCs. Using the Swedish Family-Cancer Database on non-Hodgkin lymphoma (NHL), we assessed the influence of family history on risk of SPCs and of SPCs on survival. NHL patients were identified from the years 1958 to 2015 and generalized Poisson models were used to calculate relative risks (RRs) for SPCs and familial SPCs. Among 14,393 NHL patients, a [...]