Mené sur 150 patientes atteintes d'un cancer gynécologique, cet essai randomisé multicentrique évalue l'intérêt d'une intervention de réadaptation dirigée par du personnel infirmier pour reconstruire la sexualité et l'intimité après les traitements anticancéreux

Multicentre Randomized Controlled Trial of a Nurse-Led Sexual Rehabilitation Intervention to Rebuild Sexuality and Intimacy After Treatment for Gynecological Cancer

Chow, Ka Ming ; Porter-Steele, Janine ; Siu, Ka Yi ; Shum, Wai Man ; Lee, Woon Lai ; Choi, Kai Chow ; Chan, Carmen W. H.

Objective: To evaluate the effectiveness of a sexual rehabilitation program, SEXHAB, in improving sexual functioning, reducing sexual distress, and enhancing marital satisfaction for women after gynecological cancer treatment. Methods: This is a randomized controlled trial that included 150 women newly diagnosed with gynecological cancer from three public hospitals in Hong Kong. Participants were randomly assigned to the intervention group (n = 78) to receive the SEXHAB or to an attention [...]

A partir d'une revue de la littérature publiée entre 2000 et 2023 (58 études, 4 615 patientes), cette étude évalue l'efficacité d'exercices physiques et/ou d'interventions nutritionnelles pour améliorer la qualité de vie des patientes atteintes d'un cancer du sein traité par radiothérapie

The effectiveness of exercise and/or nutritional interventions to improve the quality of life of women with breast cancer receiving radiation therapy: a scoping review

Feighan, Laura ; MacDonald-Wicks, Lesley ; Callister, Robin ; Surjan, Yolanda

Currently, in Australia, 1 in 8 women are diagnosed with breast cancer. A common adjuvant treatment for breast cancer is radiation therapy (RT). The amalgamation of side effects caused by RT treatment can ultimately affect a patient’s quality of life (QoL). With increasing breast cancer survival, a greater focus on the non-lethal consequences of this disease and its treatment is warranted. Exercise and nutrition have proven beneficial in promoting and supporting overall health and managing [...]

A partir d'une revue de la littérature, cette étude identifie les interventions visant à modifier les comportements de santé des patientes ayant survécu à un cancer du sein

Narrative Review of Lifestyle Interventions in Breast Cancer Survivors: Current Evidence and Future Directions

Gabel, Kelsey ; Chakos, Kaitlin ; Oliveira, Manoela Lima ; Sanchez Perez, Julienne ; Cares, Kate ; Salvatierra Lima, Natalia ; Ganschow, Pamela ; Yanez, Betina ; Gadi, Vijayakrishna ; Tussing-Humphreys, Lisa

Background: One in eight females will be diagnosed with breast cancer in their lifetime. While medical advances have increased the likelihood of survival, up to 90% of females will gain weight during and after treatment increasing the risk of breast cancer recurrence and obesity related co-morbidities in survivorship. Behavioral lifestyle interventions focused on diet with or without physical activity can provide breast cancer survivors non-pharmacological options to decrease weight gain and [...]

Menée en Chine, cette étude estime l'incidence des cancers (32 localisations) sur la période 1983-2017 puis présente des projections jusqu'en 2032

Trends in Cancer Incidence and Potential Associated Factors in China

Li, Mandi ; Hu, Meijing ; Jiang, Lin ; Pei, Jiao ; Zhu, Cairong

Importance : Timely analysis of cancer incidence trends is crucial for cancer prevention and control, which is a public health priority in China. Objective : To estimate incidence trends for 32 cancers in China from 1983 to 2017 and project changes to 2032, assessing distinct changes due to risk factors and an aging population. Design, Setting, and Participants : This population-based cohort study used data from the Cancer Incidence in Five Continents database (1983-2017). New cases of 32 [...]

Menée à partir de données portant sur 483 patientes afro-américaines atteintes d'un cancer épithélial de l'ovaire (âge : 20-79 ans ; durée médiane de suivi : 4,3 ans), cette étude de cohorte prospective évalue l'association entre la qualité de l'alimentation et la survie

Diet and Survival in Black Women With Epithelial Ovarian Cancer

Armidie, Tsion A. ; Bandera, Elisa V. ; Johnson, Courtney E. ; Peres, Lauren C. ; Haller, Kristin ; Terry, Paul ; Akonde, Maxwell ; Peters, Edward S. ; Coté, Michele L. ; Hastert, Theresa A. ; Collin, Lindsay J. ; Epstein, Michael ; Marks, Jeffrey ; Bondy, Melissa ; Lawson, Andrew B. ; Alberg, Anthony J. ; Schildkraut, Joellen M. ; Qin, Bo

Importance : Ovarian cancer survival among Black women is the lowest across all racial and ethnic groups. Poor dietary quality also disproportionately affects Black populations, but its association with ovarian cancer survival in this population remains largely unknown. Objective : To examine associations between dietary patterns and survival among Black women diagnosed with epithelial ovarian cancer (EOC). Design, Setting, and Participants : This prospective cohort study was conducted among [...]

Menée en Espagne à partir de données portant sur 9 113 patients atteints d'un cancer du poumon diagnostiqué entre 1994 et 2019, cette étude analyse l'évolution de la survie et identifie les facteurs pronostiques

Lung cancer survival trends and prognostic factors: A 26-year population-based study in Girona Province, Spain

Teixidor-Vilà, Eduard ; Trallero, Jan ; Puigdemont, Montse ; Vidal-Vila, Anna ; Hernández-Martínez, Alejandro ; Sais, Elia ; Sabaté-Ortega, Josep ; Verdura, Sara ; Menendez, Javier A. ; Bosch-Barrera, Joaquim ; Sanvisens, Arantza ; Marcos-Gragera, Rafael

Background: Lung cancer (LC) is Europe’s primary cause of cancer-related mortality largely due to its historically low survival rates. The aim of this study was to analyze 26-year survival trends in the province of Girona, Spain, and to identify key prognostic factors. Methods: Population-based study of LC cases collected between 1994 and 2019, with follow-up until December 31, 2021. Variables included date of diagnosis, sex, age, histology, and tumor stage (the latter since 2010). Diagnosis [...]

Menée à partir de données portant sur 886 hommes atteints d'un cancer de la prostate de grade 1 (âge médian au diagnostic : 66 ans ; durée médiane de suivi : 6,5 ans), cette étude de cohorte prospective analyse l'association entre la qualité de l'alimentation, le potentiel inflammatoire de l'alimentation et l'évolution de la maladie pendant la surveillance active

Diet Quality, Dietary Inflammatory Potential, and Risk of Prostate Cancer Grade Reclassification

Su, Zhuo Tony ; Mamawala, Mufaddal ; Landis, Patricia K. ; de la Calle, Claire M. ; Shivappa, Nitin ; Wirth, Michael ; Hebert, James R. ; Pavlovich, Christian P. ; Trock, Bruce J.

Importance : It remains unclear whether diet may influence the risk of prostate cancer grade reclassification in men undergoing active surveillance. Objective : To assess the association of diet quality and dietary inflammatory potential with prostate cancer grade reclassification during active surveillance. Design, Setting, and Participants : This prospective cohort study included men diagnosed with grade group (GG) 1 prostate cancer from January 2005 to February 2017 who were undergoing [...]

Menée à partir de données des registres américains des cancers portant sur 343 397 patientes atteintes d'un carcinome canalaire invasif et sur 39 859 patientes atteintes d'un carcinome lobulaire invasif, cette étude analyse les traitements et la survie en fonction du type de cancer du sein

Treatment and survival differences between patients with invasive lobular carcinoma versus invasive ductal carcinoma of the breast

Anampa, Jesus D. ; Lin, Shuwen ; Obeng-Gyasi, Samilia ; Xue, Xiaonan

Background: Invasive lobular carcinoma (ILC) exhibits differences in molecular and biological characteristics compared to invasive ductal carcinoma (IDC). We aim to compare breast cancer-specific survival (BCSS) between patients with ILC and IDC. Methods: We used data from the Surveillance, Epidemiology, and End Results database (1992-2020). Logistic regression analyses were conducted to identify factors associated with treatment modalities. We examined BCSS at different time points using a cox [...]

Menée au Danemark à partir de données portant sur 372 630 témoins et 74 526 patientes ayant survécu à un cancer du sein diagnostiqué entre 1966 et 2021, cette étude évalue le risque de diabète de type 2 après les traitements anticancéreux

Risk of type-2-diabetes after breast cancer treatment: a population-based cohort study in Denmark

Kjærgaard, Kasper A ; Kousholt, Astrid ; Thomsen, Reimar W ; Woolpert, Kirsten M ; Sørensen, Henrik T ; Borgquist, Signe ; Cronin-Fenton, Deirdre

Purpose: Data on type 2 diabetes (T2D) risk after breast cancer (BC) could guide preventive strategies. Yet, studies had limitations regarding sample size, follow-up, and contemporary treatments. We evaluated the risk of T2D after BC overall, by cancer treatment, and compared with a matched cohort of cancer-free women. Methods: We assembled a population-based cohort of early-stage BC patients aged  [...]

A partir d'une revue systématique de la littérature publiée jusqu'en septembre 2023 (9 articles), cette étude identifie les facteurs associés au risque de suicide chez les patientes atteintes d'un cancer gynécologique ou d'un cancer du sein

Suicide in Gynecological and Breast Cancer: A Systematic Review

Simonetti, Alessio ; Ferrara, Ottavia Marianna ; Kotzalidis, Georgios D. ; Bernardi, Evelina ; Restaino, Antonio ; Moccia, Lorenzo ; Camardese, Giovanni ; Mazza, Marianna ; Scambia, Giovanni ; Sani, Gabriele

Objectives: Depression and suicide rates are high among cancer sufferers. Women with breast and gynecological cancer show high levels of distress, depressive symptoms, cognitive impairment, and anxiety. Understanding suicide rates and risk factors in this population would represent a viable tool in planning tailored, prevention strategies. The objective of this study was to estimate suicide rate and identify the determinants of suicide risk in women with breast and other gynecologic cancer. [...]

A partir d'une revue systématique de la littérature publiée entre 2012 et 2022 (51 études), cette étude analyse l'association entre des symptômes d'anxiété et/ou de dépression et le vieillissement biologique et fonctionnel chez des patients ayant survécu à un cancer

Systematic Review of Associations between Anxiety, Depression, and Functional/Biological aging among Cancer Survivors

Streck, Brennan Parmelee ; Sass, Dilorom ; Brick, Rachelle ; Fisk, Leah ; Livinski, Alicia A ; Guida, Jennifer L

Background: Evidence suggests a mind-body component to aging, through which psychological distress from anxiety and depression drives molecular changes that promote early decline (ie, accelerated aging). Cancer survivors experience particularly high rates of anxiety and depression. Some survivors also have accelerated aging, though the relationships between anxiety/depression and aging are not clear. A synthesis of evidence is needed to understand the state of the science and impending [...]

Mené sur 57 patientes atteintes d'un cancer du sein, cet essai randomisé évalue l'effet d'une intervention comportant des exercices d'aérobie sur leurs fonctions cognitives et leur qualité de vie après la fin de la chimiothérapie

Aerobic exercise and CogniTIVe functioning in women with breAsT cancEr (ACTIVATE): A randomized controlled trial

Brunet, Jennifer ; Sharma, Sitara ; Zadravec, Kendra ; Taljaard, Monica ; LeVasseur, Nathalie ; Srikanthan, Amirrtha ; Bland, Kelcey A. ; Sabri, Elham ; Collins, Barbara ; Hayden, Sherri ; Simmons, Christine ; Smith, Andra M. ; Campbell, Kristin L.

Background : As the prevalence of chemotherapy-related cognitive impairment rises, investigation into treatment options is critical. The objectives of this study were to test the effects of an aerobic exercise intervention initiated during chemotherapy compared to usual care (wait list control condition) on (1) objectively measured cognitive function and self-reported cognitive function, as well as on (2) the impact of cognitive impairment on quality of life (QOL) postintervention (commensurate [...]

Mené en Allemagne sur 70 patientes traitées pour un cancer du sein, cet essai randomisé évalue l'intérêt d'une psychothérapie sur application mobile pour améliorer leur bien-être psychosocial

Effects of Mobile Application-Based Cognitive Behavioral Therapy on Psychological Outcomes in Women Treated for Breast Cancer: A Randomized Controlled Pilot Trial in Germany

Heinrich, Ria ; Schilling, Georgia ; Wojtyna, Ewa ; Arnold, Dirk ; Geisler, Mareike ; Kley, Susanne ; Grudzinski, Piotr ; Księżak, Małgorzata ; Schoenfelder, Tonio

Objective: Breast cancer has a strong impact on the mental state of those affected. Cognitive behavioral therapy (CBT) is one effective approach to reduce disease burden. This randomized controlled pilot trial aimed to assess the effect of the digital CBT-based application Living Well on psychological outcomes in a German female breast cancer population. Methods: Female breast cancer patients (n = 70) with ongoing or finished oncological treatment that is who were receiving or had received any [...]