A partir d'une revue systématique de la littérature (28 études), cette méta-analyse évalue l'effet, sur le taux de consommation maximale d'oxygène (VO2max) et la santé cardiorespiratoire, d'exercices physiques chez les patients atteints d'un cancer

Effect of therapeutic exercise on peak oxygen consumption in oncological population: a systematic review with meta-analysis

del-Rosal-Jurado, Alicia ; González-Sánchez, Manuel ; Cuesta-Vargas, Antonio Ignacio

Introduction: Cancer is amongst the leading causes of death worldwide. A total of 19.3 million new cases were diagnosed in 2020. Cardiovascular impairment is the second leading cause of death in patients undergoing cancer treatment. By measuring the maximum rate of oxygen consumption (VO2max) in cancer patients, it is possible to estimate their cardiorespiratory health. This study aims to show how participants’ VO2max increases with a therapeutic physical exercise programme. Methods: Four [...]

Menée en Allemagne par enquête en ligne auprès de 148 médecins en oncologie, cette étude analyse leurs connaissances concernant la fatigue liée au cancer et sa prise en charge

Physicians’ perspectives on cancer-related fatigue management and their suggestions for improvements in medical training: a cross-sectional survey study in Germany

Wagner, Anna S. ; Wehlen, L. ; Milzer, Marlena ; Schmidt, Martina E. ; Kiermeier, Senta ; Maatouk, Imad ; Steindorf, Karen

Purpose: Contrary to guidelines, many cancer patients are not screened for cancer-related fatigue (CRF) and do not receive information or adequate treatment. As physicians play a key role in cancer therapy, their knowledge of this common sequela and perspectives on its management are of major interest. Methods: For an online survey, physicians working in oncology in Germany were systematically drawn from registers and invited by using institutional newsletters or colleagues. Descriptive [...]

Menée à partir de données portant sur 185 pays et territoires, cette étude transversale analyse, pour l'année 2022, la prévalence de 36 types de cancers et la mortalité associée puis présente des projections jusqu'en 2050

Global Disparities of Cancer and Its Projected Burden in 2050

Bizuayehu, Habtamu Mellie ; Ahmed, Kedir Y. ; Kibret, Getiye Dejenu ; Dadi, Abel F. ; Belachew, Sewunet Admasu ; Bagade, Tanmay ; Tegegne, Teketo Kassaw ; Venchiarutti, Rebecca L. ; Kibret, Kelemu Tilahun ; Hailegebireal, Aklilu Habte ; Assefa, Yibeltal ; Khan, Md Nuruzzaman ; Abajobir, Amanuel ; Alene, Kefyalew Addis ; Mengesha, Zelalem ; Erku, Daniel ; Enquobahrie, Daniel A. ; Minas, Tsion Zewdu ; Misgan, Eyaya ; Ross, Allen G.

Importance : Cancer prevention and care efforts have been challenged by the COVID-19 pandemic and armed conflicts, resulting in a decline in the global Human Development Index (HDI), particularly in low- and middle-income countries. These challenges and subsequent shifts in health care priorities underscore the need to continuously monitor cancer outcome disparities and statistics globally to ensure delivery of equitable and optimal cancer prevention and care in uncertain times. Objective: To [...]

Menée aux Etats-Unis sur la période 2002-2019 à partir de données portant sur 244 519 adolescents âgés de 12 à 17 ans, cette étude identifie les facteurs psychosociaux et les facteurs liés à la santé associés au tabagisme

Cumulative Psychosocial and Health Disparities in US Adolescent Cigarette Smoking, 2002 to 2019

Erath, Tyler G ; Chen, Fang Fang ; DeSarno, Michael ; Devine, Derek ; Leventhal, Adam M ; Bickel, Warren K ; Higgins, Stephen T

Background: Understanding disparities in adolescent cigarette smoking is important for effective prevention. Methods: We investigated disparities in adolescent smoking based on cumulative reported psychosocial/health risk among respondents ages 12-17 years in the US National Survey of Drug Use and Health from 2002 to 2019. Multivariable regression estimated associations of cumulative risk, survey years, and their interaction predicting past-month and daily smoking. Eleven psychosocial/health [...]

A partir d'une revue systématique de la littérature publiée entre 2000 et 2023 (41 études), cette méta-analyse compare le stade du cancer au diagnostic chez les personnes migrantes et chez les non-migrantes

Comparing cancer stage at diagnosis between migrants and non-migrants: a meta-analysis

Harvey-Sullivan, Adam ; Ali, Sana ; Dhesi, Parveen ; Hart, Joseph ; Painter, Helena ; Walter, Fiona M. ; Funston, Garth ; Zenner, Dominik

Background: Migrants face barriers accessing healthcare, risking delays in cancer diagnosis. Diagnostic delays result in later stage diagnosis which is associated with poorer cancer survival. This review aims to compare the differences in cancer stage at diagnosis between migrants and non-migrants. Methods: We conducted a systematic review and meta-analysis of three databases from 2000 to 2023 for studies conducted in OECD countries that compared stage at diagnosis between migrants and [...]

Menée à partir des données GLOBOCAN 2022, cette étude internationale analyse l'incidence des cancers chez les adolescents et jeunes adultes (âge : 15-39 ans) ainsi que la mortalité et présente des projections jusqu'en 2050

The current and future global burden of cancer among adolescents and young adults: a population-based study

Hughes, Taylor ; Harper, Andrew ; Gupta, Sumit ; Frazier, A. Lindsay ; van der Graaf, Winette T. A. ; Moreno, Florencia ; Joseph, Adedayo ; Fidler-Benaoudia, Miranda M.

Background: Compared with children and older adults, the burden of cancer in adolescents and young adults (ages 15–39) is understudied. We aimed to quantify the global burden of adolescent and young adult cancer in 2022 and 2050, and explore patterns in incidence, mortality, and case fatality. Methods: In this population-based study, we used the GLOBOCAN database to quantify the number of new cases and cancer-related deaths, and corresponding age-standardised incidence and mortality rates [...]

Cet article examine l'incidence du cancer du pancréas chez les jeunes américains et la mortalité spécifique

Increasing Incidence and Stable Mortality of Pancreatic Cancer in Young Americans

Vishal R. Patel, ; Adewole S. Adamson, ; Jason B. Liu, ; H. Gilbert Welch

Background: Reports from several registries have garnered concerns over the increasing incidence of pancreatic cancer among younger persons, particularly women, in the United States (1, 2) and globally (3). Although some attribute this trend to increasing rates of obesity, others have found no obvious cause. Increasing cancer incidence, however, may not reflect increased true cancer occurrence but instead increased diagnostic scrutiny. If cancer occurrence is truly increasing, incidence and [...]

Menée aux Etats-Unis à partir de données 2012-2020 portant sur 6  539  001 vétérans (âge médian : 65 ans), cette étude de cohorte rétrospective analyse la prévalence et l'incidence du cancer de la prostate ainsi que le stade de la maladie et la mortalité associée en fonction de l'origine ethnique

Racial and Ethnic Differences in Prostate Cancer Epidemiology Across Disease States in the VA

Stock, Shannon R. ; Burns, Michael T. ; Waller, Justin ; De Hoedt, Amanda M. ; Parrish, Joshua A. ; Ghate, Sameer ; Kim, Jeri ; Shui, Irene M. ; Freedland, Stephen J.

Importance: Prostate cancer (PC) care has evolved rapidly as a result of changes in prostate-specific antigen testing, novel imaging, and newer treatments. The impact of these changes on PC epidemiology and racial disparities across disease states remains underexplored. Objective : To characterize racial and ethnic differences in the epidemiology of PC states, including nonmetastatic hormone-sensitive PC (nmHSPC), metastatic HSPC (mHSPC), nonmetastatic castration-resistant PC (nmCRPC), and [...]

Menée à partir de données portant sur 1 495 patients atteints d'un cancer de la vessie sans envahissement musculaire (durée médiane de suivi : 4,6 ans), cette étude de cohorte multicentrique évalue l'association entre des comportements tabagiques et le risque de progression ou de récidive de la maladie (517 cas de récidive, 163 cas de progression)

Smoking behavior and the risks of tumor recurrence and progression in patients with non-muscle-invasive bladder cancer

Kiebach, Joann ; Beeren, Ivy ; Aben, Katja K. H. ; Witjes, J. Alfred ; van der Heijden, Antoine G. ; Kiemeney, Lambertus A. L. M. ; Vrieling, Alina

Studies on the relationship of cigarette smoking with the risks of recurrence and progression of non-muscle-invasive bladder cancer (NMIBC) are inconsistent and prospective data are scarce. Therefore, we aimed to assess the association of smoking behavior with risks of NMIBC recurrence and progression. We used data of the prospective multi-center cohort study UroLife, including 1495 patients with NMIBC who reported information on smoking at 6 weeks post-diagnosis (baseline; reflecting present [...]

Mené sur 64 patients ayant survécu à un cancer (âge : 25-73 ans ; durée moyenne de suivi : 7 ans), cet essai randomisé évalue l'intérêt, pour réduire leur peur de la récidive de la maladie, d'une intervention virtuelle dispensée en groupe et utilisant des pratiques "corps-esprit"

Pilot Randomized Controlled Trial of IN FOCUS: A Mind-Body Resiliency Intervention for Fear of Cancer Recurrence

Hall, Daniel L. ; Yeh, Gloria Y. ; O'Cleirigh, Conall ; Wagner, Lynne I. ; Peppercorn, Jeffrey ; Denninger, John ; Hirschberg, April M. ; Lee, Hang ; Markwart, Michaela ; Siefring, Emma ; Mizrach, Helen R. ; Li, Raissa ; Mian, Zainab ; Tsuchiyose, Erika ; Wen, Angela ; Bullock, Andrea J. ; Park, Elyse R.

Introduction: Fear of cancer recurrence (FCR) is prevalent and distressing among survivors of cancer. Evidence-based mind-body and cognitive-behavioral skills lack integration and testing in scalable formats. Objective: This pilot randomized controlled trial (NCT04876599) tested a synchronous, virtual mind-body group resiliency intervention for FCR (IN FOCUS). Method: Adults with elevated FCR (FCR Inventory severity ≥ 16; 16–21 = elevated, 22–36 = clinically elevated) after completing primary [...]

A partir d'une revue systématique de la littérature (21 études, 44 812 patients), cette méta-analyse évalue l'association entre un mode de vie sain mesuré par des scores et la santé psychique de patients ayant survécu à un cancer

Combined healthy lifestyle factors and psychosocial outcomes among cancer survivors: a systematic review and meta-analysis

Zhu, Chunsu ; Lian, Zhiwei ; Arndt, Volker ; Thong, Melissa S. Y.

Purpose: This systematic review aims to summarize the associations between combined healthy lifestyles and psychosocial outcomes (health-related quality of life (HRQOL), depression, anxiety, psychological distress (PD), and posttraumatic stress disorder (PTSD)) among cancer survivors. Methods: PubMed, Web of Science, Cochrane Library, and EMBASE were searched for observational and interventional studies examining healthy lifestyle scores (HLS, calculated by a combination of at least three [...]

Menée aux Etats-Unis à partir de données portant sur 6 051 patientes atteintes d'un cancer du sein (âge médian au diagnostic : 57 ans), cette étude de cohorte rétrospective analyse l'association entre la présence de troubles dépressifs majeurs, le risque de récidive et la mortalité

Impact of major depressive disorder on breast cancer outcomes: a national retrospective cohort study

Aboumrad, Maya ; Joshu, Corinne ; Visvanathan, Kala

Background: Establishing whether women with major depressive disorder (MDD) who develop breast cancer (BC) have poor outcomes is key to optimizing care for this population. To address this, we examined associations between MDD and BC recurrence and mortality. Methods: Using medical record data from the Veterans Affairs Healthcare System, we established a retrospective cohort of women with local or regional stage invasive BC between 2010 and 2019 and followed through 2022. We used a two-year [...]

Menée aux Etats-Unis à partir de données portant sur 9 154 patientes atteintes d'un cancer du sein invasif après la ménopause (durée médiane de suivi : 8,6 ans), cette étude analyse l'association entre des facteurs psychosociaux (soutien social, événements stressants de la vie, etc.) et la mortalité spécifique et toutes causes confondues (3 218 décès)

Social Support, Social Strain, Stressful Life Events and Mortality Among Postmenopausal Women With Breast Cancer

Wang, Fengge ; Simon, Michael S. ; Kroenke, Candyce H. ; Krok-Schoen, Jessica ; Jung, Su Yon ; Chlebowski, Rowan ; Ballinger, Tarah J. ; Pichardo, Margaret S. ; Coday, Mace ; Garcia, Lorena ; Luo, Juhua

Introduction: Social support, social strain and stressful life events could induce chronic stress, which affects prognosis and survival after breast cancer diagnosis. However, few studies have examined the impact of psychosocial factors on different competing mortality events. Methods: We included 9154 postmenopausal women who were newly diagnosed with invasive breast cancer after enrollment in the Women's Health Initiative, as of March 6th, 2021. Psychosocial factors were collected and [...]

Menée auprès de 691 patients atteints d'un gliome de haut grade, cette étude multicentrique identifie les facteurs associés à la présence et à la fréquence de troubles psychiques communs

Frequency and clinical associations of common mental disorders in adults with high-grade glioma—A multicenter study

Singer, Susanne ; Schranz, Melanie ; Hippler, Melina ; Kuchen, Robert ; Weiß Lucas, Carolin ; Meixensberger, Jürgen ; Fehrenbach, Michael Karl ; Keric, Naureen ; Mitsdoerffer, Meike ; Gempt, Jens ; Coburger, Jan ; Kessler, Almuth Friederike ; Wehinger, Jens ; Misch, Martin ; Onken, Julia ; Rapp, Marion ; Voß, Martin ; Nadji-Ohl, Minou ; Mehlitz, Marcus ; Tatagiba, Marcos ; Tabatabai, Ghazaleh ; Renovanz, Mirjam

Background: One third of adults with cancer suffer from common mental disorders in addition to their malignant disease. However, it is unknown whether this proportion is the same in patients who have brain tumors and which factors modulate the risk for psychiatric comorbidity. Methods: In a multicenter study, patients with high-grade glioma at 13 neurooncology clinics were enrolled consecutively and interviewed with the Structured Clinical Interview for the Diagnostic and Statistical Manual of [...]

Menée aux Etats-Unis à partir de données portant sur 1 008 jeunes adultes atteintes d'un cancer du sein de stade 0 à III traité entre 2006 et 2016 (âge médian au diagnostic : 36 ans), cette étude de cohorte analyse l'évolution de leurs difficultés financières jusqu'à 10 ans après le diagnostic

Financial Difficulty Over Time in Young Adults With Breast Cancer

Myers, Sara P. ; Zheng, Yue ; Dibble, Kate ; Mittendorf, Elizabeth A. ; King, Tari A. ; Ruddy, Kathryn J. ; Peppercorn, Jeffrey M. ; Schapira, Lidia ; Borges, Virginia F. ; Come, Steven E. ; Rosenberg, Shoshana M. ; Partridge, Ann H.

IMPORTANCE : Young adults aged 18 to 39 years represent the minority of breast cancer diagnoses but are particularly vulnerable to financial hardship. Factors contributing to sustained financial hardship are unknown. OBJECTIVES: To identify financial hardship patterns over time and characterize factors associated with discrete trajectories; it was hypothesized that treatment-related arm morbidity, a key source of expense, would be associated with long-term financial difficulty. DESIGN, SETTING, [...]

Menée aux Etats-Unis par enquête auprès de 27 435 patients atteints d'un cancer pendant la pandémie de COVID-19 (âge médian : 65 ans), cette étude analyse leurs expériences concernant leurs consultations médicales en ligne

Perspectives on Telemedicine Visits Reported by Patients With Cancer

Doshi, Sahil D. ; Charvadeh, Yasin Khadem ; Seier, Kenneth ; Bange, Erin M. ; Daly, Bobby ; Lipitz-Snyderman, Allison ; Polubriaginof, Fernanda C. G. ; Buckley, Michael ; Kuperman, Gilad ; Stetson, Peter D. ; Schrag, Deb ; Morris, Michael J. ; Panageas, Katherine S.

Importance : The COVID-19 pandemic catalyzed rapid adoption of telemedicine visits for cancer care delivery. However, patients’ experiences with telemedicine remain poorly understood. Objective : To understand patients’ satisfaction with telemedicine visits at a comprehensive cancer center. Design, Setting, and Participants : This survey study included patients with cancer at a US cancer center between 2020 and 2023. Eligible patients completed surveys in English conducted after their first [...]