Menée à partir de données d'enquêtes réalisées en Angleterre sur la période 2013-2024 auprès de 54 251 adultes ayant tenté et/ou réussi un sevrage tabagique, cette étude analyse la prévalence de l'utilisation des cigarettes électroniques pour soutenir les tentatives d'arrêt du tabac

Prevalence and uptake of vaping among people who have quit smoking: a population study in England, 2013-2024

Jackson, Sarah E. ; Brown, Jamie ; Kock, Loren ; Shahab, Lion

Background: Vaping prevalence has increased rapidly in England since 2021. This study estimated trends between 2013 and 2024 in vaping among ex-smokers, overall and among those who did not use e-cigarettes to support their quit attempt. Methods: Data were collected via nationally-representative, monthly cross-sectional surveys in England, October 2013 to May 2024. We analysed data from 54,251 adults (≥ 18y) who reported having tried to stop smoking in the past year or having stopped smoking [...]

Menée à l'aide de données de la "UK Biobank" portant sur 50 640 personnes, cette étude analyse l'effet d'une amélioration des habitudes alimentaires sur la réduction du risque de cancer colorectal en fonction du sexe

Diet Changes and Colorectal Cancer Risk in the UK Biobank

Hoang, Tung ; Cho, Sooyoung ; Shin, Aesun

Modifying dietary behaviors into healthier habits may attenuate the risk of colorectal cancer. This study aimed to investigate the association between dietary changes and the risk of colorectal cancer.Following dietary recommendations for red and processed meat, fruit and vegetables, and alcohol consumption, we classified 50,640 participants into poor and good adherence groups in the UK Biobank. Changes in dietary habits were defined as stable poor, poor to good, good to poor, and stable to [...]

Menée par modélisation à partir de données américaines publiées, cette étude évalue le rapport coût-efficacité d'une extension du vaccin nonavalent contre le papillomavirus humain aux adultes âgés de 27 à 45 ans à plus haut risque d'infection

Cost-Effectiveness of Extending Human Papillomavirus Vaccination to Population Subgroups Older Than 26 Years Who Are at Higher Risk for Human Papillomavirus Infection in the United States

Laprise, Jean-François ; Chesson, Harrell W. ; Markowitz, Lauri E. ; Drolet, Mélanie ; Brisson, Marc

Background: In June 2019, the U.S. Advisory Committee on Immunization Practices recommended shared clinical decision making regarding potential human papillomavirus (HPV) vaccination of men and women aged 27 to 45 years (?mid-adults?). Objective: To examine the incremental cost-effectiveness ratios (ICERs) and number needed to vaccinate (NNV) to prevent 1 HPV-related cancer case of expanding HPV vaccination to subgroups of mid-adults at increased risk for HPV-related diseases in the United [...]

Menée à partir de données néerlandaises portant sur 2 519 femmes porteuses d'une mutation BRCA (durée médiane de suivi : 13,4 ans), cette étude analyse l'incidence à long terme et les facteurs de risque d'un carcinome séreux de haut grade après une salpingo-ovariectomie prophylactique

High-grade serous carcinoma occurring after risk-reducing salpingo-oophorectomy in BRCA1/2 germline pathogenic variant carriers

Stroot, Iris A S ; Bart, Joost ; Hollema, Harry ; Wagner, Marise M ; Yigit, Refika ; van Doorn, Helena C ; de Hullu, Joanne A ; Gaarenstroom, Katja N ; van Beurden, Marc ; van Lonkhuijzen, Luc R C W ; Slangen, Brigitte F M ; Zweemer, Ronald P ; Gómez Garcia, Encarna B ; Ausems, Margreet G E M ; Komdeur, Fenne L ; van Asperen, Christi J ; Adank, Muriel A ; Wevers, Marijke R ; Hooning, Maartje J ; Hebon Investigators ; Mourits, Marian J E ; de Bock, Geertruida H

Risk-reducing salpingo-oophorectomy (RRSO) effectively prevents high-grade serous carcinoma (HGSC) in BRCA1/2 germline pathogenic variant (GPV) carriers. Still, some women develop HGSC after RRSO without pathologic findings. This study assessed long-term incidence and risk factors for developing HGSC after RRSO without pathologic findings.BRCA1/2 GPV carriers were selected from Hereditary Breast and Ovarian cancer in the Netherlands (HEBON) cohort. Follow-up data for HGSC after RRSO were [...]