A partir d'une revue systématique de la littérature (31 articles, 1 298 patients), cette étude analyse l'utilisation de dispositifs portables, notamment ceux permettant de mesurer l'activité physique, chez les patients âgés atteints d'un cancer (âge supérieur ou égal à 60 ans)

The use of wearable technology in studies in older adults with cancer: a systematic review

Duin, Jan J ; Baltussen, Joosje C ; Albalak, Gali ; van Dam van Isselt, Eléonore F ; Portielje, Johanneke E A ; Mooijaart, Simon P ; Soto-Perez-de-Celis, Enrique ; van den Bos, Frederiek

Despite the increasing integration of wearable technology in oncology, its application in the care of older adults, representing most patients with cancer, is poorly defined.This systematic review aimed to summarize the current use of wearables in studies in older adults with cancer.This systematic review was conducted following the PRISMA guidelines. A systematic search was conducted in PubMed, Embase, Emcare, Web of Science, and Cochrane Library on May 1, 2024. Studies involving wearable [...]

Menée en Belgique par enquête auprès de 37 professionnels de santé, cette étude analyse leurs pratiques de prise en charge de la douleur des patients atteints d'un cancer et traités dans des unités hospitalières de soins de support ou de soins palliatifs

Evaluating pain management practices for cancer patients among health professionals in cancer and supportive/palliative care units: a Belgian survey

Fontaine, Christel ; Libert, Isabelle ; Echterbille, Marie-Aline ; Bonhomme, Vincent ; Botterman, Jacky ; Bourgonjon, Bram ; Brouillard, Vincent ; Courtin, Yannick ; De Buck, Joke ; Debruyne, Philip R. ; Delaat, Martine ; Delperdange, Jean-Michel ; Duck, Lionel ; Everaert, Els ; Lamot, Caroline ; Holbrechts, Stéphane ; Lossignol, Dominique ; Krekelbergh, Francis ; Langenaeken, Christine ; Lapeire, Lore ; Naert, Eline ; Lauwers, Koen ; Matic, Milica ; Mebis, Jeroen ; Miedema, Geertje ; Pieterbourg, Michèle ; Plehiers, Barbara ; Punie, Kevin ; Roblain, Françoise ; Schrijvers, Dirk ; Serre, Charles-Henri ; Vandenborre, Katherine ; Broecke, Anne Vanden ; Van den Bulk, Heidi ; Vanopdenbosch, Ludo ; Van Ryckeghem, Florence ; Verheezen, Jolanda ; Verschaeve, Vincent ; Voordeckers, Mia ; Klastersky, Jean

Background: Pain is reported in 66% of cancer patients with advanced disease. Adequate pain management is a cornerstone of comprehensive supportive cancer care. Purpose: The purpose of this study was to assess pain management in Oncology Units in Belgium. Methods: A descriptive research design was applied. A structured questionnaire developed by a writing committee was sent to 37 healthcare professionals in 2021. Twenty-four replied. Results: In most centers, pain management is organized [...]

Menée par enquête auprès de 243 patients atteints d'un cancer traité à l'extérieur de l'hôpital, cette étude analyse le risque d'aversions alimentaires induites par la chimiothérapie puis évalue l'impact de ces aversions sur le statut nutritionnel

Incidence and impact of food aversions among patients with cancer receiving outpatient chemotherapy: a one-year prospective survey

Suka, Machi ; Katsube, Atsushi ; Fujimoto, Reiko ; Uwagawa, Tadashi ; Shimada, Takashi ; Yano, Shingo ; Yamauchi, Takashi ; Yanagisawa, Hiroyuki

Purpose: To determine the current incidence and impact of chemotherapy-associated food aversions in a variety of cancer types. Methods: Cancer patients aged 18 years and older who received chemotherapy infusions at the outpatient chemotherapy unit of a university hospital between May 2022 and April 2023 were included in the study (n = 243). To monitor the occurrence of food aversions, participants were asked to complete a food preference questionnaire each time they visited the outpatient [...]

Mené sur 139 personnes ayant reçu une greffe de cellules souches hématopoïétiques, cet essai multicentrique évalue les effets sur les capacités physiques d'une intervention en ligne dispensant un programme personnalisé comportant des exercices aérobie, des exercices de résistance, une formation sur la gestion du stress et une initiation à la pratique de la pleine conscience

Randomized Controlled Trial of a Virtually Delivered Exercise and Stress Management Program to Improve Physical Performance of Hematopoietic Cell Transplant Survivors

David D. Ma ; Zhixin Liu ; Kimberley Au ; Mei Tran ; Crisbel M. Artuz ; Matthew Greenwood ; Ian Bilmon ; David Kliman

Purpose : Because of advances in hematopoietic cell transplant (HCT), meeting the long-term health needs of increasing numbers of HCT survivors remains challenging. This multicenter trial aimed to assess the short- and long-term effects of an exercise and mindfulness intervention delivered by telehealth. Methods : One hundred thirty-nine participants >6 months post-HCT were randomly assigned 1:1 to a 6-week personalized exercise and mindfulness training with three motivation sessions at 3-6 [...]

Mené sur 166 patients atteints d'un cancer du poumon métastatique ou localement avancé et présentant une toux sévère ou modérée liée à la maladie, cet essai randomisé en double aveugle évalue l'efficacité de la prégabaline pour réduire la sévérité de la toux

Pregabalin for chronic cough due to lung cancer: randomized, double-blind, placebo-controlled trial

Noronha, Vanita ; Menon, Nandini ; Patil, Vijay M. ; Shah, Minit ; Joshi, Amit ; Shah, Srushti ; Nawale, Kavita ; Surve, Rohan ; Bafna, Gunj ; Jogdhankar, Shweta ; Shelar, Priyanka ; Shetake, Ankush ; Singh, Ashish ; Salian, Sushmita ; Jadhav, Pundlik ; Shah, Hetakshi ; Mer, Neha ; Vohra, Ananya ; Majumdar, Swaratika ; Banavali, Shripad ; Badwe, Rajendra ; Prabhash, Kumar

Background : Developing effective therapies for cough in lung cancer is an unmet need Neuromodulators like pregabalin may act centrally as cough suppressants. Methods : Randomized double-blind placebo-controlled study in patients with locally advanced/metastatic lung cancer and at least 2 weeks of moderate or severe cough. Randomization was 1:1 to pregabalin 300 mg orally daily or matching placebo, both administered for 9 weeks. Primary endpoint was the change in cough severity as measured by [...]

Menée auprès de 241 patients atteints d'un cancer colorectal, cette étude transversale examine l'association entre des facteurs sociodémographiques et cliniques et la présence d'une fatigue liée à la maladie

Prevalence of cancer-related fatigue syndrome and its association with sociodemographic and clinical characteristics in adult patients with colorectal cancer: a cross-sectional study

Lorca, Luz Alejandra ; Ribeiro, Ivana Leao ; Pizarro, Marta ; Rebolledo Rebolledo, Gonzalo

Purpose: To describe the prevalence of fatigue in adults with colorectal cancer (CRC). Additionally, to explore the associations and correlations between fatigue and sociodemographic and clinical characteristics. Methods: Patients with CRC at various phases of the disease were evaluated for fatigue using the Brief Fatigue Inventory (BFI), independence in activities of daily living using the Barthel index, perception of pain using the Visual Analogue Scale (VAS), and performance status using the [...]

Menée à partir de données taïwanaises portant sur 3 785 enfants de père ayant survécu à un cancer diagnostiqué entre 15 et 40 ans, cette étude analyse le risque obstétrique lié à ces antécédents paternels

Adverse birth and obstetric outcomes in the offspring of male adolescent and young adult cancer survivors: A nationwide population-based study

Kao, Wei-Heng ; Chuang, Yi-Fang ; Huang, Yi-Wei ; Chen, Po-Jui ; Liu, Yu-Cheng ; Wang, Chun-Chieh ; Hsu, Jun-Te ; Shueng, Pei-Wei ; Kuo, Chang-Fu

Background: The growing population of male adolescent and young adult (AYA, 15-40 years old) cancer survivors has heightened interest in their reproductive health. However, studies have reported conflicting findings on the potential risks of cancer and its treatments on birth and obstetric outcomes. Methods: We utilized encrypted identification numbers for both fathers and mothers to link three nationwide Taiwan datasets from 2004 to 2019, identifying 3,785 births with a paternal history of AYA [...]

Menée à partir des données 1990-2021 de l'Organisation Mondiale de la Santé, cette étude analyse l'évolution de la mortalité par cancer chez les patients âgés de moins de 50 ans dans 15 pays à revenu intermédiaire supérieur ou élevé

Trends in cancer mortality under age 50 in 15 upper-Middle and high-income countries

Santucci, Claudia ; Mignozzi, Silvia ; Alicandro, Gianfranco ; Pizzato, Margherita ; Malvezzi, Matteo ; Negri, Eva ; Jha, Prabhat ; La Vecchia, Carlo

Background: Rising cancer incidence, particularly for colorectal cancer, has been reported in young adults. This study examined whether this is related to an increase in mortality. Methods: We analysed World Health Organization (WHO) mortality data among young adults aged 25-49 in 15 most populous upper-middle and high-income countries from 1990 to 2021 with reliable data. Mid-year populations were retrieved from the United Nations for the American Countries and from the WHO for the other [...]

Menée à partir de données de "GLOBOCAN 2022", cette étude estime l'incidence du cancer et la mortalité chez les personnes âgées d'au moins 80 ans puis réalise une projection pour 2050 au niveau mondial et par pays, en fonction du revenu national et du sexe

Updated cancer burden in oldest old: A population-based study using 2022 Globocan estimates

Shah, Richa ; Battisti, Nicolo Matteo Luca ; Brain, Etienne ; Gnangnon, Freddy H. R. ; Kanesvaran, Ravindran ; Mohile, Supriya ; Noronha, Vanita ; Puts, Martine ; Soto-Perez-de-Celis, Enrique ; Pilleron, Sophie

Background: The global population aged 80 years or older is expected to triple by 2050, leading to an increased cancer burden in the oldest population. This study describes the estimated cancer incidence and mortality in 2022 and projections for 2050 in the oldest old, analyzed globally and by world regions and World Bank income levels, for all sexes combined, as well as separately for males and females. Methods: Using GLOBOCAN 2022 estimates, we reported the estimated number of new cancer [...]

Menée à partir de données de la base "EUROCARE-6", cette étude analyse l'incidence de 10 types de tumeur solide rare de l'adulte et la survie associée depuis les années 2000 dans 29 Etats de l'Union Européenne

Incidence and survival of rare adult solid cancers in Europe (EUROCARE-6): a population-based study

Trama, Annalisa ; Bernasconi, Alice ; Canete, Adela ; Carulla, Marià ; Daubisse-Marliac, Laetitia ; Rossi, Silvia ; De Angelis, Roberta ; Sanvisens, Arantza ; Katalinic, Alexander ; Paapsi, Keiu ; Went, Philip ; Mousavi, Mohsen ; Blum, Marcel ; Eberle, Andrea ; Lamy, Sébastien ; Riccardo, Capocaccia ; Didonè, Fabio ; Botta, Laura

Background: Rare cancers correspond to approximately 200 clinical entities, which can be grouped into 12 families. Updated data are available for childhood and haematological cancers, ie, for only two of the 12 families of rare cancer. We provide incidence and survival for the remaining ten families of rare adult solid cancers (RAC), across 29 EU Member States and over time. We also evaluate the association between resources invested in health and survival from RACs. Methods: We used the [...]

Menée aux Etats-Unis à partir de données 1995-2022 portant sur 134 366 patients atteints d'un cancer de la prostate, cette étude de cohorte analyse l'incidence de la maladie et la mortalité spécifique en fonction de l'origine ethnique et du lieu de vie (zone économiquement défavorisée)

Association of Race and Area of Deprivation Index with Prostate Cancer Incidence and Lethality

Finati, Marco ; Stephens, Alex ; Cirulli, Giuseppe Ottone ; Chiarelli, Giuseppe ; Tinsley, Shane ; Morrison, Chase ; Sood, Akshay ; Buffi, Nicolo ; Lughezzani, Giovanni ; Salonia, Andrea ; Briganti, Alberto ; Montorsi, Francesco ; Busetto, Gian Maria ; Rogers, Craig ; Carrieri, Giuseppe ; Abdollah, Firas

Background: Socio-economic and demographical factors contribute to disparity in prostate cancer (PCa) outcomes. We examined the impact of area of deprivation index (ADI) and race on PCa incidence and lethality in a North-American cohort. Methods: Our cohort included men who received at least one PSA test within our Health System (1995-2022). An ADI score was assigned to each patient based on their residential census block, ranked as a percentile of deprivation relative to the national level. [...]

Menée à partir de données des registres américains des cancers et de la base Medicare, cette étude analyse l'association entre le lieu de résidence et l'accès aux traitements en fonction de l'origine ethnique des patients atteints d'un cancer de la prostate

The Association of Where Patients with Prostate Cancer Live and Receive Care on Racial Treatment Inequities

Hammarlund, Noah ; Holt, Sarah K ; Etzioni, Ruth ; Morehead, Danté ; Lee, Jenney R ; Wolff, Erika M ; Burrola-Mendez, Yohali ; Sage, Liz ; Gore, John L ; Nyame, Yaw A

Black individuals are less likely to be treated for prostate cancer even though they are more than twice as likely to die compared to White individuals. The complex causes of these inequities are influenced by social and structural factors, including racism, which contribute to the differential delivery of care. This study investigates how factors related to the location of where individuals live and receive care affect treatment inequities for prostate cancer between Black and White [...]

Menée sur la période 2010-2020, cette étude analyse l'intérêt d'une surveillance active pour un cancer de la prostate à risque intermédiaire

Active Surveillance or Watchful Waiting for Intermediate-Risk Prostate Cancer, 2010-2020

Ajjawi, Ismail ; Loeb, Stacy ; Cooperberg, Matthew R. ; Catalona, William J. ; Gross, Cary P. ; Ma, Xiaomei ; Leapman, Michael S.

Active surveillance and watchful waiting, periods of observation rather than early treatment, are considered optimal initial management strategies for individuals with nonaggressive prostate cancer.A recent surveillance study found low risks of metastasis (1.4%) and cancer mortality (0.1%) with active surveillance in individuals with primarily low–risk prostate cancer, typically defined as the lowest Gleason grade groups (GGs), prostate-specific antigen (PSA) levels, and clinical stages.

Menée à partir de données du registre californien des cancers portant sur 22 834 patients atteints d'un cancer colorectal de survenue précoce diagnostiqué sur la période 2000-2019 (âge médian : 44 ans ; durée moyenne de suivi : 4,2 ans), cette étude de cohorte analyse la survie en fonction de l'origine ethnique

Racial and Ethnic Variation in Survival in Early-Onset Colorectal Cancer

Demb, Joshua ; Gomez, Scarlett L. ; Canchola, Alison J. ; Qian, Alexander ; Murphy, James D. ; Winn, Robert A. ; Banegas, Matthew P. ; Gupta, Samir ; Martínez, María Elena

Importance : Rates of early-onset (before 50 years of age) colorectal cancer (EOCRC) are increasing, with notable differences across racial and ethnic groups. Limited data are available on EOCRC-related mortality differences when disaggregating racial and ethnic groups. Objective : To investigate racial and ethnic differences in EOCRC mortality, including disaggregation of Asian American populations separately, including Native Hawaiian or Other Pacific Islander populations and specific Asian [...]

Menée à partir des données des registres américains des cancers, cette étude évalue la prévalence d'un adénocarcinome colorectal chez les patients pédiatriques (âge inférieur à 18 ans) puis analyse les caractéristiques de la maladie et la survie associée

A SEER Registry–Based Analysis of Pediatric Colorectal Adenocarcinomas

Emile, Sameh Hany ; Horesh, Nir ; Garoufalia, Zoe ; Gefen, Rachel ; Dourado, Justin ; Wexner, Steven D.

Colorectal cancer (CRC) in people younger than 20 years occurs in 0.5 per 100 000 in the US. Previous population-based pediatric CRC studies analyzed patients younger than 21 years and histologic types of cancer, each with different characteristics and prognoses than adenocarcinomas. We assessed the characteristics and survival outcomes of colorectal adenocarcinomas in patients younger than 18 years.

Menée à partir de données 2000-2018 des registres américains des cancers portant sur 771 681 patientes ayant survécu à un cancer du sein, cette étude analyse le risque de second cancer au cours du suivi

Patterns of subsequent cancer incidence over time in patients with breast cancer

Deng, Zhengyi ; Visvanathan, Kala

Background: Breast cancer survivors face a higher risk of subsequent primary cancers. This study investigated the patterns of subsequent cancer risk according to time since breast cancer diagnosis. Methods: Using data from the Surveillance, Epidemiology, and End Results program (2000-2018), we identified a cohort of 771,681 breast cancer survivors. Standard incidence ratios (SIR) were calculated by comparing the observed to the expected number of subsequent cancers over different follow-up [...]

Cette étude analyse les tendances récentes de la mortalité par cancer du col de l'utérus chez les Américaines de moins de 25 ans

Cervical Cancer Mortality Among US Women Younger Than 25 Years, 1992-2021

Dorali, Poria ; Damgacioglu, Haluk ; Clarke, Megan A. ; Wentzensen, Nicolas ; Orr, Brian C. ; Sonawane, Kalyani ; Deshmukh, Ashish A.

Human papillomavirus (HPV) vaccination has been recommended for routine use in US women since June 2006. Studies from 2022 and 2023 indicated a 12% per year decline (overall, 65% reduction) in cervical cancer incidence during 2012 to 2019 among US women younger than 25 years who likely benefited from HPV vaccination. Because a reduction in mortality follows a reduction in incidence, we evaluated recent trends in cervical cancer mortality among young women.

Menée à partir de données 2011-2020 portant sur 117 347 patients ayant reçu une greffe de cellules souches hématopoïétiques (90 747 cas de greffe autologue et 26 600 cas de greffe allogénique), cette étude identifie des facteurs associés au risque de troubles psychologiques puis évalue l'impact de ces troubles sur la survie à court terme et sur les ré-admissions hospitalières

Psychological Risk Factors on Hematopoietic Stem Cell Transplantation Patients: Insights From National Readmission Database Analysis

Zhang, Qi ; Yu, Qiuyan ; Chen, Qian ; Dong, Hongjing ; Fang, Min ; Liu, Na ; Li, Wen ; Wang, Hui ; Zhao, Nan ; Zhu, Xunxun ; Zhang, Kui ; Zhou, Chi

Background: Psychosocial risk factors (PSRFs) have emerged as important nontraditional risk factors for poor medical outcomes but have not been well-studied in the field of hematopoietic stem cell transplantation (HSCT). Objectives: In this study, we retrospectively examined in-hospital and short-term outcomes in patients with PSRFs who underwent HSCT. Methods: We used the National Readmission Database (NRD) to identify patients who underwent HSCT between 2011 and 2020. Patients were stratified [...]

A partir d'une revue systématique de la littérature (10 études, 1 409 patientes), cette méta-analyse évalue l'efficacité de thérapies cognitivo-comportementales dispensées sur internet pour soulager les symptômes de détresse et améliorer la qualité de vie de patientes ayant survécu à un cancer du sein

Effect of Internet-Based Cognitive Behavioral Therapy on Psychological Distress and Quality of Life Among Breast Cancer Survivors: A Meta-Analysis of Randomized Controlled Trials

Li, Mengjie ; Liu, Fangli ; Han, Xinxin ; Li, Jiaxin ; Fan, Yujun

Objectives : This meta-analysis was to critically evaluate the effectiveness of Internet-based Cognitive Behavioral Therapy (ICBT) on psychological distress and quality of life in breast cancer survivors. Methods: A search was conducted across eleven databases (PubMed, Web of Science, Embase, Cochrane Library, Scopus, ProQuest, CINAHL, CBM, CNKI, VIP and Wanfang) to identify relevant randomized controlled trials (RCTs) published from databases inception to September 2023. Two reviewers [...]

Menée aux Etats-Unis à partir de données 2004-2020 portant sur 10 120 patients infectés par le VIH et atteints d'un cancer de stade IV, cette étude analyse les facteurs associés à l'accès à des soins palliatifs

Inequities in palliative care delivery to patients with HIV and Stage IV cancers in the US (2004-2020)

Islam, Jessica Y ; Guo, Yi ; Turner, Kea ; Tabriz, Amir Alishahi ; Lin, Yu Chen ; Vidot, Denise C ; Vadaparampil, Susan T ; Coghill, Anna E ; ScD, Marlene Camacho-Rivera ; Suneja, Gita

Background: People with HIV (PWH) diagnosed with stage-IV cancer are less likely to receive palliative care (PC) compared to those without HIV. Our objective was to evaluate inequities in PC receipt among PWH with stage IV cancer in the US. Methods: We used the National Cancer Database (2004-2020), including adult (18-89 years) PWH with the 14 most common cancers that occur among PWH. PC was defined as treatment provided with non-curative intent. Our main exposures included % quartiles of [...]

A partir de l'analyse des paiements reçus par les panélistes ayant participé à l'élaboration des recommandations du "National Comprehensive Cancer Network" (NCCN) pour les 20 cancers les plus répandus, cette étude examine les tendances concernant l'application de la politique du NCCN sur les conflits d'intérêts financiers

Trends in Enforcement of National Comprehensive Cancer Network Financial Conflict of Interest Policy

Saririan, Niloufar ; Bhamidipati, Dedipya ; Dey, Pranam ; Persaud, Sonia ; Chakraborty, Nirjhar ; Tabatabai, Sara ; Gallagher, Grace ; Trivedi, Niti U ; Mitchell, Aaron P

The National Comprehensive Cancer Network (NCCN) financial conflict of interest (FCOI) policy sets dollar maximums for panelists, but violations may occur.We studied NCCN Guidelines panelists for the 20 most prevalent cancers, 2013-2022. We included panelists with ≥1 calendar year of service (“current panelists”) and those who began service during the study period (“new panelists”); NCCN FCOI policy limits ($20,000 from any single company or $50,000 across all companies) applies to both groups. [...]

Menée auprès de 645 patients ayant survécu à un cancer, cette étude analyse l'intérêt, pour faciliter les discussions patient-médecin, d'une application permettant le suivi de la santé cardiovasculaire

Effectiveness of a Cardiovascular Health Electronic Health Record Application for Cancer Survivors in Community Oncology Practice: Results From WF-1804CD

Kathryn E. Weaver ; Emily V. Dressler ; Heidi D. Klepin ; Simon C. Lee ; Brian J. Wells ; Sydney Smith ; W. Gregory Hundley ; Glenn J. Lesser ; Chandylen L. Nightingale ; Julie C. Turner ; Ian Lackey ; Kevin Heard ; Randi Foraker ; Brian Wells ; Heidi Klepin ; Philip Payne ; Albert Lai ; Simon Craddock Lee ; Jay W. Carlson ; Marcia L. Hernandez ; Jenny Hanna ; Heide Alexandra Rodgers ; Sonia J. Varghese ; Alyssa D. Throckmorton ; Rajiv Panikkar ; Paula Ronjon ; Joshua Lukenbill ; Ann Louise Stroh ; Adedayo A. Onitilo ; Lindsey W. Kulbacki ; Khalid Matin ; Mary Helen Hackney

Purpose: Guidelines recommend cardiovascular (CV) risk assessment and counseling for cancer survivors. This study evaluated the automated heart-health assessment (AH-HA) clinical decision support tool to promote provider-patient CV health (CVH) discussions in outpatient oncology. Methods: The AH-HA trial (WF-1804CD), coordinated by the Wake Forest National Cancer Institute Community Oncology Research Program Research Base, randomized practices to the AH-HA tool or usual care (UC) and enrolled [...]