Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Pour retrouver les publications signalées par Nota Bene Cancer (archives indexées à partir du n°127 du 1" mars 2012) :
Sommaire du n° 604 du 17 mai 2024
Lutte contre les cancers
Qualité de vie, soins de support (6)
Menée aux Etats-Unis auprès de 540 patients ayant survécu à un cancer (âge moyen : 61,1 ans) et de 87 aidants (âge moyen : 62,3 ans) issus de minorités ethniques et médicalement défavorisés, cette étude analyse l'intérêt d'un programme destiné à améliorer l'activité physique, les fonctions physiques et la qualité de vie après les traitements anticancéreux
Expanding active living after cancer to underserved cancer survivors and their caregivers
Menée aux Etats-Unis auprès de 540 patients ayant survécu à un cancer (âge moyen : 61,1 ans) et de 87 aidants (âge moyen : 62,3 ans) issus de minorités ethniques et médicalement défavorisés, cette étude analyse l'intérêt d'un programme destiné à améliorer l'activité physique, les fonctions physiques et la qualité de vie après les traitements anticancéreux
Expanding active living after cancer to underserved cancer survivors and their caregivers
Mama, Scherezade K ; Mitchell, Stacy J ; Tracy, Patricia V ; Pena, Luz Y ; Moreno, Carolina D ; Valdes, Adriana ; Liao, Yue ; Lee, Che Young ; Alexander, Ashley ; Raber, Margaret R ; Mcneill, Lorna H ; Basen-Engquist, Karen
Background: Physical activity (PA) improves physical and psychological health in cancer survivors. This study evaluated Active Living After Cancer (ALAC), a community-based program to improve PA, physical function, and quality of life (QOL) in minority and medically underserved cancer survivors and their caregivers. Methods: Participants completed 12 weekly ALAC sessions and assessments of PA, physical functioning, and QOL at baseline and follow-up (week 12). Paired samples t-tests were used to [...]
Mené sur 81 patientes atteintes d'un cancer de l'ovaire, cet essai randomisé évalue l'intérêt d'une intervention combinant exercices physiques et conseils alimentaires pour réduire la fatigue et améliorer le fonctionnement physique
Effects of a combined exercise and dietary intervention on body composition, physical functioning and fatigue in patients with ovarian cancer: resu...
Mené sur 81 patientes atteintes d'un cancer de l'ovaire, cet essai randomisé évalue l'intérêt d'une intervention combinant exercices physiques et conseils alimentaires pour réduire la fatigue et améliorer le fonctionnement physique
Effects of a combined exercise and dietary intervention on body composition, physical functioning and fatigue in patients with ovarian cancer: results of the PADOVA trial
Kenkhuis, Marlou-Floor ; Stelten, Stephanie ; Hartman, Yvonne A. W. ; Brouwer, Calvin G. ; ten Tusscher, Marieke R. ; van Lonkhuijzen, Luc R. C. W. ; Kenter, Gemma G. ; van Driel, Willemien J. ; Winkels, Renate M. ; Bekkers, Ruud L. M. ; Ottevanger, Nelleke P. B. ; Hoedjes, Meeke ; Buffart, Laurien M.
Background: Guidelines recommend to include exercise and dietary advice in standard care for patients with cancer, based on evidence primarily derived from patients with breast cancer. Its applicability to patients with ovarian cancer is uncertain due to differences in patient characteristics and treatments. The PADOVA trial examined the effectiveness of a combined exercise and dietary intervention on fat-free mass (FFM), physical functioning, and fatigue. Methods: In total, 81 patients with [...]
Mené sur 151 patients ayant survécu à un cancer du poumon de stade avancé, cet essai randomisé compare l'intérêt, pour prendre en charge les déficiences cognitives et les symptômes psycho-neurologiques, d'exercices aérobiques et d'une pratique de Tai Chi
Comparative effect of Tai Chi and aerobic exercise on cognitive function in advanced lung cancer survivors with perceived cognitive impairment: a t...
Mené sur 151 patients ayant survécu à un cancer du poumon de stade avancé, cet essai randomisé compare l'intérêt, pour prendre en charge les déficiences cognitives et les symptômes psycho-neurologiques, d'exercices aérobiques et d'une pratique de Tai Chi
Comparative effect of Tai Chi and aerobic exercise on cognitive function in advanced lung cancer survivors with perceived cognitive impairment: a three-arm randomized controlled trial with mediation analysis
Takemura, Naomi ; Cheung, Denise Shuk Ting ; Fong, Daniel Yee Tak ; Lee, Anne Wing Mui ; Lam, Tai-Chung ; Ho, James Chung-Man ; Kam, Tsz Yeung ; Chik, Jeannie Yin Kwan ; Lin, Chia-Chin
Purpose: Cancer-related cognitive impairment is prevalent in metastatic lung cancer survivors. This study aimed to compare the effectiveness of aerobic exercise and Tai Chi on perceived cognitive function and the mediating role of psychoneurological symptoms with perceived cognitive impairment. Methods: In a subgroup of a parent randomized clinical trial, participants who reported cognitive impairment underwent a 16-week aerobic exercise (n = 49), Tai Chi (n = 48), and control (n = 54) groups. [...]
Mené sur 276 patientes ayant survécu à un cancer du sein, cet essai de phase III évalue l'efficacité du donépézil pour traiter les déficiences cognitives et les troubles de la mémoire, 1 à 5 ans après une chimiothérapie adjuvante
Phase III Randomized, Placebo-Controlled Clinical Trial of Donepezil for Treatment of Cognitive Impairment in Breast Cancer Survivors After Adjuvan...
Mené sur 276 patientes ayant survécu à un cancer du sein, cet essai de phase III évalue l'efficacité du donépézil pour traiter les déficiences cognitives et les troubles de la mémoire, 1 à 5 ans après une chimiothérapie adjuvante
Phase III Randomized, Placebo-Controlled Clinical Trial of Donepezil for Treatment of Cognitive Impairment in Breast Cancer Survivors After Adjuvant Chemotherapy (WF-97116)
Stephen R. Rapp ; Emily V. Dressler ; W. Mark Brown ; James L. Wade III ; Nguyet Le-Lindqwister ; David King ; Kendrith M. Rowland ; Kathryn E. Weaver ; Heidi D. Klepin ; Edward G. Shaw ; Glenn J. Lesser
Purpose: To test efficacy of donepezil, a cognitive enhancer, to improve memory in breast cancer survivors who report cancer-related cognitive impairment 1-5 years postchemotherapy. Patients and Methods: Adult female BCS exposed to ≥4 cycles of adjuvant chemotherapy 1-5 years before enrollment who reported cancer-related cognitive impairment were eligible. Participants, enrolled at sites affiliated with the Wake Forest NCI Community Oncology Research Program (NCORP) Research Base, were randomly [...]
Mené sur 258 patients atteints d'un cancer de la tête et du cou (âge moyen : 65 ans), cet essai multicentrique randomisé évalue l'efficacité de l'acupuncture pour traiter une xérostomie induite par la radiothérapie
Acupuncture for Chronic Radiation-Induced Xerostomia in Head and Neck Cancer: A Multicenter Randomized Clinical Trial
Mené sur 258 patients atteints d'un cancer de la tête et du cou (âge moyen : 65 ans), cet essai multicentrique randomisé évalue l'efficacité de l'acupuncture pour traiter une xérostomie induite par la radiothérapie
Acupuncture for Chronic Radiation-Induced Xerostomia in Head and Neck Cancer: A Multicenter Randomized Clinical Trial
Cohen, Lorenzo ; Danhauer, Suzanne C. ; Garcia, M. Kay ; Dressler, Emily V. ; Rosenthal, David I. ; Chambers, Mark S. ; Cusimano, Andrew ; Brown, W. Mark ; Ochoa, Jewel M. ; Yang, Peiying ; Chiang, Joseph S. ; Gordon, Ora ; Crutcher, Rhonda ; Kim, Jung K. ; Russin, Michael P. ; Lukenbill, Joshua ; Porosnicu, Mercedes ; Yost, Kathleen J. ; Weaver, Kathryn E. ; Lesser, Glenn J.
Importance : Patients with head and neck cancer who undergo radiotherapy can develop chronic radiation-induced xerostomia. Prior acupuncture studies were single center and rated as having high risk of bias, making it difficult to know the benefits of acupuncture for treating radiation-induced xerostomia. Objective : To compare true acupuncture (TA), sham acupuncture (SA), and standard oral hygiene (SOH) for treating radiation-induced xerostomia. Design, Setting, and Participants : A randomized, [...]
Cette étude présente les recommandations de l'"American Society of Clinical Oncology" et de l'"International Society of Oral Oncology-Multinational Association for Supportive Care in Cancer" concernant la prévention et la prise en charge d'une ostéoradionécrose chez les patients atteints d'un cancer de la tête et du cou traité par radiothérapie
Prevention and Management of Osteoradionecrosis in Patients With Head and Neck Cancer Treated With Radiation Therapy: ISOO-MASCC-ASCO Guideline
Cette étude présente les recommandations de l'"American Society of Clinical Oncology" et de l'"International Society of Oral Oncology-Multinational Association for Supportive Care in Cancer" concernant la prévention et la prise en charge d'une ostéoradionécrose chez les patients atteints d'un cancer de la tête et du cou traité par radiothérapie
Prevention and Management of Osteoradionecrosis in Patients With Head and Neck Cancer Treated With Radiation Therapy: ISOO-MASCC-ASCO Guideline
Douglas E. Peterson ; Shlomo A. Koyfman ; Noam Yarom ; Charlotte Duch Lynggaard ; Nofisat Ismaila ; Lone E. Forner ; Clifton David Fuller ; Yvonne M. Mowery ; Barbara A. Murphy ; Erin Watson ; David H. Yang ; Ivan Alajbeg ; Paolo Bossi ; Michael Fritz ; Neal D. Futran ; Daphna Y. Gelblum ; Edward King ; Salvatore Ruggiero ; Derek K. Smith ; Alessandro Villa ; Jonn S. Wu ; Deborah Saunders
Purpose: To provide evidence-based recommendations for prevention and management of osteoradionecrosis (ORN) of the jaw secondary to head and neck radiation therapy in patients with cancer. Methods: The International Society of Oral Oncology-Multinational Association for Supportive Care in Cancer (ISOO-MASCC) and ASCO convened a multidisciplinary Expert Panel to evaluate the evidence and formulate recommendations. PubMed, EMBASE, and Cochrane Library databases were searched for randomized [...]
Observation (6)
Menée aux Etats-Unis à partir de données portant sur 74 563 femmes et 39 501 hommes sans antécédent de cancer (durées médianes de suivi : 34 et 31 ans), cette étude de cohorte analyse l'association entre une consommation d'aliments ultra-transformés et la mortalité, notamment par cancer
Association of ultra-processed food consumption with all cause and cause specific mortality: population based cohort study
Menée aux Etats-Unis à partir de données portant sur 74 563 femmes et 39 501 hommes sans antécédent de cancer (durées médianes de suivi : 34 et 31 ans), cette étude de cohorte analyse l'association entre une consommation d'aliments ultra-transformés et la mortalité, notamment par cancer
Association of ultra-processed food consumption with all cause and cause specific mortality: population based cohort study
Zhe Fang ; Sinara Laurini Rossato ; Dong Hang ; Neha Khandpur ; Kai Wang ; Chun-Han Lo ; Walter C Willett ; Edward L Giovannucci ; Mingyang Song
Objective: To examine the association of ultra-processed food consumption with all cause mortality and cause specific mortality. Design: Population based cohort study. Setting: Female registered nurses from 11 US states in the Nurses’ Health Study (1984-2018) and male health professionals from all 50 US states in the Health Professionals Follow-up Study (1986-2018). Participants: 74 563 women and 39 501 men with no history of cancer, cardiovascular diseases, or diabetes at baseline. Main [...]
Ultra-processed foods linked to higher mortality
Menée aux Etats-Unis à partir de données portant sur 74 563 femmes et 39 501 hommes sans antécédent de cancer (durées médianes de suivi : 34 et 31 ans), cette étude de cohorte analyse l'association entre une consommation d'aliments ultra-transformés et la mortalité, notamment par cancer
Ultra-processed foods linked to higher mortality
Kathryn E Bradbury ; Sally Mackay
Debate about the “ultra-processed” concept must not delay food policies that improve health. As research into ultra-processed food gains momentum,1 so too does the debate.234 Foods that fall into the ultra-processed category according to the Nova classification are heterogeneous and include carbonated soft drinks, confectionary, extruded snack foods, distilled alcohol (spirits), and mass produced packaged wholegrain bread.5 Ultra-processed foods are typically high in energy, added sugar, [...]
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Two-Year-Span Breast Cancer Screening Uptake in Japan after the COVID-19 Pandemic and Its Association with the COVID-19 Vaccination
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Two-Year-Span Breast Cancer Screening Uptake in Japan after the COVID-19 Pandemic and Its Association with the COVID-19 Vaccination
Abubakar, Aminu Kende ; Kaneda, Yudai ; Ozaki, Akihiko ; Saito, Hiroaki ; Murakami, Michio ; Hori, Daisuke ; Gonda, Kenji ; Tsubokura, Masaharu ; Tabuchi, Takahiro
There is limited information on whether the COVID-19 pandemic was associated with decreased breast cancer screening uptake and if COVID-19 vaccination was associated with an increase in screening uptake. Our study explored the uptake of breast cancer screening in Japan after the COVID-19 pandemic and assessed its association with the COVID-19 vaccination. We analyzed data from the Japan COVID-19 and Society Internet Survey (JACSIS), a web-based prospective cohort survey, and we included 6110 [...]
Causes and impact of delays during the COVID-19 pandemic on head and neck cancer diagnosis
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Causes and impact of delays during the COVID-19 pandemic on head and neck cancer diagnosis
Gete, Maru ; Huang, Shao Hui ; Ringash, Jolie ; Irish, Jonathan ; Su, Jie ; Ballal, Yashi ; Waldron, John N. ; Witterick, Ian ; de Almeida, John ; Hosni, Ali ; Hope, Andrew J. ; Monteiro, Eric ; Cho, John ; O'Sullivan, Brian ; Kim, John ; Bratman, Scott ; Goldstein, David P. ; McPartlin, Andrew ; Tsai, Jillian ; Tong, Li ; Xu, Wei ; Hahn, Ezra
Background: The causes for delays during the COVID19 pandemic and their impact on head and neck cancer (HNC) diagnosis and staging are not well described. Methods: Two cohorts were defined a priori for review and analysis—a Pre-Pandemic cohort (June 1 to December 31, 2019) and a Pandemic cohort (June 1 to December 31, 2020). Delays were categorized as COVID-19 related or not, and as clinician, patient, or policy related. Results: A total of 638 HNC patients were identified including 327 in the [...]
Impact of COVID-19 on patients with metastatic breast cancer: REthink Access to Care and Treatment survey results
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Impact of COVID-19 on patients with metastatic breast cancer: REthink Access to Care and Treatment survey results
Neil M Iyengar ; Clay Williams ; Michael Rogan ; Laurie Campbel ; Shirley Mertz ; Jeremy Block ; Maria Ebling ; Connie Chen ; Justin Doan ; Samantha K Kurosky ; Timothy J Pluard
Aim: Patients with metastatic breast cancer (MBC) may be vulnerable to changes in healthcare management, safety standards and protocols that occurred during the COVID-19 pandemic. Materials & methods: The REthink Access to Care & Treatment (REACT) survey assessed USA-based patient perspectives on COVID-19-related impacts to their MBC treatment experience between 27 April 2021 and 17 August 2021. Results: Participants (n = 341; 98.5% females, mean age 50.8 years) reported that overall oncology [...]
Impact of the COVID-19 pandemic on breast cancer patient pathways and outcomes in the United Kingdom and the Republic of Ireland – a scoping review
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Impact of the COVID-19 pandemic on breast cancer patient pathways and outcomes in the United Kingdom and the Republic of Ireland – a scoping review
Lohfeld, Lynne ; Sharma, Meenakshi ; Bennett, Damien ; Gavin, Anna ; Hawkins, Sinéad T. ; Irwin, Gareth ; Mitchell, Helen ; O’Neill, Siobhan ; McShane, Charlene M.
The COVID-19 pandemic brought unplanned service disruption for breast cancer diagnostic, treatment and support services. This scoping review describes these changes and their impact in the UK and the Republic of Ireland based on studies published between January 2020 and August 2023. Thirty-four of 569 papers were included. Data were extracted and results thematically organized. Findings include fewer new cases; stage shift (fewer early- and more late-stage disease); and changes to healthcare [...]
The Assessment of Social Isolation and Loneliness in Cancer Patients and Survivors in the Pre-COVID-19 Period: A Systematic Review
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The Assessment of Social Isolation and Loneliness in Cancer Patients and Survivors in the Pre-COVID-19 Period: A Systematic Review
Marziliano, Allison ; Byakova, Alla ; Patel, Priya ; Herman, Saori W. ; Diefenbach, Michael A.
Background: In the context of cancer research, identifying social isolation and loneliness is a priority given how both exacerbate poor outcomes and lead to increased mortality in oncological populations. The purpose of this systematic review is to identify all quantitative instruments that have been used to assess either social isolation or loneliness in patients previously or currently diagnosed with cancer in the pre-COVID-19 period. Method: PubMed (Web), Scopus, CINAHL, and PsycINFO were [...]
Lessons learned from COVID-19: improving breast cancer care post-pandemic from the patient perspective
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Lessons learned from COVID-19: improving breast cancer care post-pandemic from the patient perspective
Myers, Charlotte ; Bennett, Kathleen ; Cahir, Caitriona
Background: Since the onset of the pandemic, breast cancer (BC) services have been disrupted in most countries. The purpose of this qualitative study is to explore the unmet needs, patient-priorities, and recommendations for improving BC healthcare post-pandemic for women with BC and to understand how they may vary based on social determinants of health (SDH), in particular socio-economic status (SES). Methods: Thirty-seven women, who were purposively sampled based on SDH and previously [...]
The experience of surgical cancer patients during the COVID-19 pandemic at a large cancer centre in London
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
The experience of surgical cancer patients during the COVID-19 pandemic at a large cancer centre in London
Russell, Beth ; Hadi, Hajer ; Moss, Charlotte L. ; Green, Saran ; Haire, Anna ; Wylie, Harriet ; Handford, Jasmine ; Monroy-Iglesias, Maria ; Dickinson, Harvey ; Haire, Kate ; Van Hemelrijck, Mieke
Background: The COVID-19 pandemic has had an enormous impact on the experiences of patients across all health disciplines, especially those of cancer patients. The study aimed to understand the experiences of cancer patients who underwent surgery during the first two waves of the pandemic at Guy’s Cancer Centre, which is a large tertiary cancer centre in London. Methods: A mixed-methods approach was adopted for this study. Firstly, a survey was co-designed by the research team and a patient [...]
Impact of COVID-19 pandemic among patients with lung and head and neck cancer assisted in a public cancer center in Brazil
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée à la COVID-19
Impact of COVID-19 pandemic among patients with lung and head and neck cancer assisted in a public cancer center in Brazil
Viana Veloso, Gilson Gabriel ; Amaral, Flávia Duarte ; Nogueira-Rodrigues, Angelica
Background: There is no updated national data regarding the real impact of the COVID-19 pandemic on delaying diagnosis and treatment among patients with lung, and head, and neck cancers in Brazil. This study aimed to analyze the COVID-19 pandemic impact on cancer diagnosis and clinical outcomes among lung, head, and neck cancer patients assisted in a tertiary cancer center in Southeastern Brazil, as well as to analyze these patients’ pretreatment clinical features. Methods: Retrospective cohort [...]
A partir d'une revue systématique de la littérature, cette étude fait le point sur l'association entre une utilisation d'opioïdes et la survie des patients atteints d'un cancer traité par inhibiteurs de point de contrôle immunitaire
Association of opioid use with survival in patients with cancer treated with immune checkpoint inhibitors: it is time for evidence-based behaviors
A partir d'une revue systématique de la littérature, cette étude fait le point sur l'association entre une utilisation d'opioïdes et la survie des patients atteints d'un cancer traité par inhibiteurs de point de contrôle immunitaire
Association of opioid use with survival in patients with cancer treated with immune checkpoint inhibitors: it is time for evidence-based behaviors
Giusti, Raffaele ; Porzio, Giampiero ; Maltoni, Marco ; Filetti, Marco ; Cuomo, Arturo ; Bandieri, Elena ; Trapani, Dario ; Bruera, Eduardo
Cancer is a leading cause of morbidity and mortality worldwide, with pain experienced by most patients undergoing cancer treatment. Opioids are the recommended treatment for cancer pain management, but recent studies suggest a negative association between opioid use and survival rates among patients undergoing immunotherapy. However, conclusions cannot be drawn regarding causality from these observational data. Immunotherapy, which boosts the body’s immune system to fight cancer cells, has [...]
Mené sur 3 020 patientes ayant survécu à un cancer du sein à haut risque de récidive et non métastatique (durée médiane de suivi : 33,8 mois), cet essai randomisé de phase III évalue l'intérêt, du point de vue de la survie sans maladie invasive, d'une utilisation quotidienne d'aspirine pour prévenir le risque de récidive
Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer: The Alliance A011502 Randomized Trial
Mené sur 3 020 patientes ayant survécu à un cancer du sein à haut risque de récidive et non métastatique (durée médiane de suivi : 33,8 mois), cet essai randomisé de phase III évalue l'intérêt, du point de vue de la survie sans maladie invasive, d'une utilisation quotidienne d'aspirine pour prévenir le risque de récidive
Aspirin vs Placebo as Adjuvant Therapy for Breast Cancer: The Alliance A011502 Randomized Trial
Chen, Wendy Y. ; Ballman, Karla V. ; Partridge, Ann H. ; Hahn, Olwen M. ; Briccetti, Frederick M. ; Irvin, William J. ; Symington, Banu ; Visvanathan, Kala ; Pohlmann, Paula R. ; Openshaw, Thomas H. ; Weiss, Anna ; Winer, Eric P. ; Carey, Lisa A. ; Holmes, Michelle D.
Importance: Observational studies of survivors of breast cancer and prospective trials of aspirin for cardiovascular disease suggest improved breast cancer survival among aspirin users, but prospective studies of aspirin to prevent breast cancer recurrence are lacking. Objective : To determine whether aspirin decreases the risk of invasive cancer events among survivors of breast cancer. Design, Setting, and Participants : A011502, a phase 3, randomized, placebo-controlled, double-blind trial [...]
The Aspirin Conundrum—Navigating Negative Results, Age, Aging Dynamics, and Equity
Mené sur 3 020 patientes ayant survécu à un cancer du sein à haut risque de récidive et non métastatique (durée médiane de suivi : 33,8 mois), cet essai randomisé de phase III évalue l'intérêt, du point de vue de la survie sans maladie invasive, d'une utilisation quotidienne d'aspirine pour prévenir le risque de récidive
The Aspirin Conundrum—Navigating Negative Results, Age, Aging Dynamics, and Equity
Mandelblatt, Jeanne S. ; Mainor, Candice ; Hudson, Barry I.
The Alliance trial led by Chen and colleagues1 and published in this issue of JAMA addresses an important topic in the management of breast cancer: can daily use of 300 mg of aspirin improve invasive disease–free survival among persons with a diagnosis of nonmetastatic, high-risk breast cancer? The answer is a fairly definitive no based on prespecified futility rules in a rigorous phase 3, randomized, placebo-controlled, double-blind trial. The trial (A011502) enrolled 3020 persons (3004 women [...]
Menée à partir de données portant sur 100 témoins et 542 patientes âgées atteintes d'un cancer du sein de stade précoce traité ou non par chimiothérapie (âge : supérieur ou égal à 65 ans), cette étude prospective analyse le déclin de leurs capacités fonctionnelles
Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older Pa...
Menée à partir de données portant sur 100 témoins et 542 patientes âgées atteintes d'un cancer du sein de stade précoce traité ou non par chimiothérapie (âge : supérieur ou égal à 65 ans), cette étude prospective analyse le déclin de leurs capacités fonctionnelles
Functional decline in older breast cancer survivors treated with and without chemotherapy and non-cancer controls: results from the Hurria Older PatiEnts (HOPE) prospective study
Sedrak, Mina S. ; Sun, Can-Lan ; Bae, Marie ; Freedman, Rachel A. ; Magnuson, Allison ; O’Connor, Tracey ; Moy, Beverly ; Wildes, Tanya M. ; Klepin, Heidi D. ; Chapman, Andrew E. ; Tew, William P. ; Dotan, Efrat ; Fenton, Mary Anne ; Kim, Heeyoung ; Katheria, Vani ; Muss, Hyman B. ; Cohen, Harvey J. ; Gross, Cary P. ; Ji, Jingran
Purpose: This study aimed to assess whether physical functional decline in older women with early-stage breast cancer is driven by cancer, chemotherapy, or a combination of both. Methods: We prospectively sampled three groups of women aged ≥ 65: 444 with early-stage breast cancer receiving chemotherapy (BC Chemo), 98 with early-stage breast cancer not receiving chemotherapy (BC Control), and 100 non-cancer controls (NC Control). Physical function was assessed at two timepoints (T1 [baseline] [...]
Menée aux Etats-Unis à partir de données portant sur 10 211 patientes ayant survécu à un cancer du sein unilatéral (durée médiane de suivi : 5,79 ans), cette étude de cohorte rétrospective évalue le risque de maladie cardiovasculaire en lien avec les traitements anticancéreux reçus (anthracycline et/ou trastuzumab, autres chimiothérapies)
Long-term cardiovascular disease risk after anthracycline and trastuzumab treatments in U.S. breast cancer survivors
Menée aux Etats-Unis à partir de données portant sur 10 211 patientes ayant survécu à un cancer du sein unilatéral (durée médiane de suivi : 5,79 ans), cette étude de cohorte rétrospective évalue le risque de maladie cardiovasculaire en lien avec les traitements anticancéreux reçus (anthracycline et/ou trastuzumab, autres chimiothérapies)
Long-term cardiovascular disease risk after anthracycline and trastuzumab treatments in U.S. breast cancer survivors
Vo, Jacqueline B ; Ramin, Cody ; Veiga, Lene H S ; Brandt, Carolyn ; Curtis, Rochelle E ; Bodelon, Clara ; Barac, Ana ; Roger, Véronique L ; Feigelson, Heather Spencer ; Buist, Diana S M ; Bowles, Erin J Aiello ; Gierach, Gretchen L ; Berrington de Gonzalez, Amy
Background: Although breast cancer survivors are at risk for cardiovascular disease (CVD) from treatment late effects, evidence to inform long-term and age-specific cardiovascular surveillance recommendations is lacking. Methods: We conducted a retrospective cohort study of 10,211 women diagnosed with first primary unilateral breast cancer in Kaiser Permanente Washington or Colorado (aged 20+, survived ≥1 year). We estimated multivariable adjusted hazard ratios (aHR) for associations between [...]
Analyses économiques et systèmes de soins (3)
Menée à partir de données de 27 pays européens portant sur 890 730 patients atteints d'une tumeur lymphoïde diagnostiquée entre 2001 et 2013 (12 types de tumeurs), cette étude rétrospective estime la survie à 5 ans et à 10 ans et analyse les dépenses de santé nationales associées
Long-term survival for lymphoid neoplasms and national health expenditure (EUROCARE-6): a retrospective, population-based study
Menée à partir de données de 27 pays européens portant sur 890 730 patients atteints d'une tumeur lymphoïde diagnostiquée entre 2001 et 2013 (12 types de tumeurs), cette étude rétrospective estime la survie à 5 ans et à 10 ans et analyse les dépenses de santé nationales associées
Long-term survival for lymphoid neoplasms and national health expenditure (EUROCARE-6): a retrospective, population-based study
Sant, Milena ; Vener, Claudia ; Lillini, Roberto ; Rossi, Silvia ; Bonfarnuzzo, Simone ; Marcos-Gragera, Rafael ; Maynadie, Marc ; Innos, Kaire ; Paapsi, Keiu ; Visser, Otto ; Bernasconi, Alice ; Demuru, Elena ; Di Benedetto, Corrado ; Mousavi, Seyed Mohsen ; Blum, Marcel ; Went, Philip ; Serraino, Diego ; Bennett, Damien ; Sánchez, María-José ; De Angelis, Roberta ; Hackl, Monika ; van Eycken, Elizabeth ; Van Damme, Nancy ; Valerianova, Zdravka ; Sekerija, Mario ; Scoutellas, Vasos ; Demetriou, Anna ; Dušek, Ladislav ; Krejici, Denisa ; Storm, Hans ; Mägi, Margit ; Pitkäniemi, Janne ; Velten, Michel ; Troussard, Xavier ; Bouvier, Anne-Marie ; Jooste, Valérie ; Guizard, Anne-Valérie ; Launoy, Guy ; Dabakuyo Yonli, Sandrine ; Woronoff, Anne-Sophie ; Nousbaum, Jean-Baptiste ; Coureau, Gaelle ; Monnereau, Alain ; Baldi, Isabelle ; Hammas, Karima ; Tretarre, Brigitte ; Colonna, Marc ; Plouvier, Sandrine ; D'Almeida, Tania ; Molinié, Florence ; Cowppli-Bony, Anne ; Bara, Simona ; Debreuve, Adeline ; Defossez, Gautier ; Lapôtre-Ledoux, Bénédicte ; Grosclaude, Pascale ; Daubisse-Marliac, Laetitia ; Luttmann, Sabine ; Eberle, Andrea ; Stabenow, Roland ; Nennecke, Alice ; Kieschke, Joachim ; Zeissig, Sylke ; Holleczek, Bernd ; Katalinic, Alexander ; Birgisson, Helgi ; Murray, Deirdre ; Walsh, Paul M. ; Mazzoleni, Guido ; Vittadello, Fabio ; Cuccaro, Francesco ; Galasso, Rocco ; Sampietro, Giuseppe ; Rosso, Stefano ; Gasparotti, Cinzia ; Maifredi, Giovanni ; Ferrante, Margherita ; Ragusa, Rosalia ; Sutera Sardo, Antonella ; Gambino, Maria Letizia ; Lanzoni, Monica ; Ballotari, Paola ; Giacomazzi, Erica ; Ferretti, Stefano ; Caldarella, Adele ; Manneschi, Gianfranco ; Gatta, Gemma ; Baili, Paolo ; Berrino, Franco ; Botta, Laura ; Trama, Annalisa ; Didonè, Fabio ; Lasalvia, Paolo ; Buratti, Lucia ; Tagliabue, Giovanna ; Dal Maso, Luigino ; Capocaccia, Riccardo ; Cerza, Francesco ; Di Mari, Fabrizio ; Santaquilani, Mariano ; Venanzi, Serenella ; Tallon, Marco ; Boni, Luca ; Iacovacci, Silvia ; Gennaro, Valerio ; Russo, Antonio Giampiero ; Gervasi, Federico ; Spagnoli, Gianbattista ; Cavalieri D'Oro, Luca ; Fusco, Mario ; Vitale, Maria Francesca ; Usala, Mario ; Mazzucco, Walter ; Michiara, Maria ; Chiranda, Giorgio ; Cascone, Giuseppe ; Rollo, Concetta Patrizia ; Mangone, Lucia ; Falcini, Fabio ; Cavallo, Rossella ; Piras, Daniela ; Madeddu, Anselmo ; Bella, Francesca ; Fanetti, Anna Clara ; Minerba, Sante ; Candela, Giuseppina ; Scuderi, Tiziana ; Rizzello, Roberto Vito ; Stracci, Fabrizio ; Rugge, Massimo ; Brustolin, Angelita ; Pildava, Santa ; Smailyte, Giedre ; Azzopardi, Miriam ; Johannesen, Tom Børge ; Didkowska, Joanna ; Wojciechowska, Urszula ; Bielska-Lasota, Magdalena ; Pais, Ana ; Bento, Maria José ; Ferreira, Ana Maia ; Lourenço, Antonio ; Safaei Diba, Chakameh ; Zadnik, Vesna ; Zagar, Tina ; Sánchez-Contador Escudero, Carmen ; Franch Sureda, Paula ; Lopez de Munain, Arantza ; De-La-Cruz, Marta ; Rojas, Marìa Dolores ; Aleman, Araceli ; Vizcaino, Ana ; Sanvisens, Arantza ; Sánchez, María José ; Chirlaque López, María Dolores ; Sánchez-Gil, Antonia ; Guevara, Marcela ; Ardanaz, Eva ; Galceran, Jaume ; Carulla, Marià ; Bergeron, Yvan ; Bouchardy, Christine ; Mohsen Mousavi, Seyed ; Bordoni, Andrea ; Stevens, Sarah ; Broggio, John ; Gavin, Anna ; Morrison, David ; Huws, Dyfed Wyn
Background: Management of lymphoid malignancies requires substantial health system resources. Total national health expenditure might influence population-based lymphoid malignancy survival. We studied the long-term survival of patients with 12 lymphoid malignancy types and examined whether different levels of national health expenditure might explain differences in lymphoid malignancy prognosis between European countries and regions. Methods: For this observational, retrospective, [...]
Finding the health-care expenditure that drives variation in cancer survival
Menée à partir de données de 27 pays européens portant sur 890 730 patients atteints d'une tumeur lymphoïde diagnostiquée entre 2001 et 2013 (12 types de tumeurs), cette étude rétrospective estime la survie à 5 ans et à 10 ans et analyse les dépenses de santé nationales associées
Finding the health-care expenditure that drives variation in cancer survival
Rutherford, Mark J.
EUROCARE 1 , 2 and other international comparison studies of cancer survival 3 , 4 provide essential evidence for reporting inequalities and monitoring population-level improvements. Research in this area continues to refute the long-standing criticisms 5 of the comparability of international survival data. Cancer survival is a key metric that reflects improvements in treatment and care for patients diagnosed with cancer (ie, trends in survival can closely map to the timing of treatment [...]
Menée aux Etats-Unis à partir de données portant sur 923 témoins et 3 475 patients ayant survécu à un cancer pédiatrique diagnostiqué entre 1970 et 1999, cette étude transversale analyse l'association entre le niveau socioéconomique de leur zone de résidence et leurs difficultés financières auto-déclarées
Financial Hardship and Neighborhood Socioeconomic Disadvantage in Long-term Childhood Cancer Survivors
Menée aux Etats-Unis à partir de données portant sur 923 témoins et 3 475 patients ayant survécu à un cancer pédiatrique diagnostiqué entre 1970 et 1999, cette étude transversale analyse l'association entre le niveau socioéconomique de leur zone de résidence et leurs difficultés financières auto-déclarées
Financial Hardship and Neighborhood Socioeconomic Disadvantage in Long-term Childhood Cancer Survivors
Fauer, Alex J ; Qiu, Weiyu ; Huang, I-Chan ; Ganz, Patricia A ; Casillas, Jacqueline N ; Yabroff, K Robin ; Armstrong, Gregory T ; Leisenring, Wendy ; Howell, Rebecca ; Howell, Carrie R ; Kirchhoff, Anne C ; Yasui, Yutaka ; Nathan, Paul C
Background: Long-term survivors of childhood cancer face elevated risk for financial hardship. We evaluate whether childhood cancer survivors live in areas of greater deprivation and the association with self-reported financial hardships. Methods: Cross-sectional analysis of data from the Childhood Cancer Survivor Study (CCSS) between 1970 and 1999, and self-reported financial information from 2017-2019. We measured neighborhood deprivation with the Area Deprivation Index (ADI) based on current [...]
Menée dans un contexte américain à partir de données portant sur 8 524 patients atteints d'un cancer traité par thérapie ciblée orale (âge : 18-24 ans), cette étude de cohorte rétrospective analyse l'association entre le bénéfice net pour la santé de ces médicaments et les dépenses, notamment les coûts restant à la charge des patients
Association between oral targeted cancer drug net health benefit, uptake, and spending
Menée dans un contexte américain à partir de données portant sur 8 524 patients atteints d'un cancer traité par thérapie ciblée orale (âge : 18-24 ans), cette étude de cohorte rétrospective analyse l'association entre le bénéfice net pour la santé de ces médicaments et les dépenses, notamment les coûts restant à la charge des patients
Association between oral targeted cancer drug net health benefit, uptake, and spending
Lau-Min, Kelsey S ; Wu, Yaxin ; Rochester, Shavon ; Bekelman, Justin E ; Kanter, Genevieve P ; Getz, Kelly D
Background: Targeted cancer drugs (TCDs) have revolutionized oncology but vary in clinical benefit and patient out-out-pocket (OOP) costs. The ASCO Value Framework uses survival, toxicity, and symptom palliation data to quantify the net health benefit (NHB) of cancer drugs. We evaluated associations between NHB, uptake, and spending on oral TCDs. Methods: We conducted a retrospective cohort study of patients aged 18-64 years with an incident oral TCD pharmacy claim in 2012-2020 in a nationwide [...]
Soins palliatifs (1)
Cette étude présente les recommandations actualisées de l'"American Society of Clinical Oncology" concernant les soins palliatifs pour les patients atteints d'un cancer
Palliative Care for Patients With Cancer: ASCO Guideline Update
Cette étude présente les recommandations actualisées de l'"American Society of Clinical Oncology" concernant les soins palliatifs pour les patients atteints d'un cancer
Palliative Care for Patients With Cancer: ASCO Guideline Update
Justin J. Sanders ; Sarah Temin ; Arun Ghoshal ; Erin R. Alesi ; Zipporah Vunoro Ali ; Cynthia Chauhan ; James F. Cleary ; Andrew S. Epstein ; Janice I. Firn ; Joshua A. Jones ; Mark R. Litzow ; Debra Lundquist ; Mabel Alejandra Mardones ; Ryan David Nipp ; Michael W. Rabow ; William E. Rosa ; Camilla Zimmermann ; Betty R. Ferrell
Purpose: To provide evidence-based guidance to oncology clinicians, patients, nonprofessional caregivers, and palliative care clinicians to update the 2016 ASCO guideline on the integration of palliative care into standard oncology for all patients diagnosed with cancer. Methods: ASCO convened an Expert Panel of medical, radiation, hematology-oncology, oncology nursing, palliative care, social work, ethics, advocacy, and psycho-oncology experts. The Panel conducted a literature search, [...]
Ressources et infrastructures (Lutte contre les cancers) (2)
Menée à partir de données portant sur 473 patients atteints d'un cancer et âgés d'au moins 75 ans, cette étude prospective multicentrique analyse la possibilité d'utiliser un outil en ligne pour déclarer leurs symptômes
FASTOCH: Feasibility of Electronic Patient-Reported Outcomes in Older Patients With Cancer—A Multicenter Prospective Study
Menée à partir de données portant sur 473 patients atteints d'un cancer et âgés d'au moins 75 ans, cette étude prospective multicentrique analyse la possibilité d'utiliser un outil en ligne pour déclarer leurs symptômes
FASTOCH: Feasibility of Electronic Patient-Reported Outcomes in Older Patients With Cancer—A Multicenter Prospective Study
Mathilde Cancel ; Carine Sauger ; Julie Biogeau ; Véronique Dardaine-Giraud ; Thierry Lecomte ; David Solub ; Pierre Combe ; Rémy Wilmet ; Eugénie Aubard ; Amandine Deloigne ; Philippe Hébrard ; Étienne Dorval
Purpose: Multiple studies have demonstrated that electronic patient-reported outcomes (ePROs) improve overall survival and quality of life in cancer care. However, there are no specific prospective data on remote ePRO monitoring in the older population, although they represent a significant proportion of patients with cancer. Patients and Methods: From February 2021 to April 2022, patients age 75 years and older under active anticancer treatment were consecutively recruited in six institutions. [...]
Cette étude identifie les facteurs associés au risque d'ostéoradionécrose chez les patients atteints d'un cancer de la tête et du cou et présente un système de classification pour prédire le risque
Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model
Cette étude identifie les facteurs associés au risque d'ostéoradionécrose chez les patients atteints d'un cancer de la tête et du cou et présente un système de classification pour prédire le risque
Development and Standardization of an Osteoradionecrosis Classification System in Head and Neck Cancer: Implementation of a Risk-Based Model
Erin E. Watson E ; Katrina Hueniken ; Junhyung Lee ; Shao Hui Huang ; Amr El Maghrabi ; Wei Xu ; Amy C. Moreno ; C. Jillian Tsai ; Ezra Hahn ; Andrew J. McPartlin ; Christopher M.K.L. Yao ; David P. Goldstein ; John R. de Almeida ; John N. Waldon ; Clifton D. Fuller ; Andrew J. Hope ; Salvatore L. Ruggiero ; Michael Glogauer ; Ali A. Hosni
Purpose: Osteoradionecrosis of the jaw (ORN) can manifest in varying severity. The aim of this study is to identify ORN risk factors and develop a novel classification to depict the severity of ORN. Methods: Consecutive patients with head and neck cancer (HNC) treated with curative-intent intensity-modulated radiation therapy (IMRT) (≥45 Gy) from 2011 to 2017 were included. Occurrence of ORN was identified from in-house prospective dental and clinical databases and charts. Multivariable [...]
