Cette étude passe en revue les données évaluant l'efficacité et la toxicité des opioïdes pour soulager la douleur des patients atteints d'un cancer

Opioid analgesics for nociceptive cancer pain: A comprehensive review

Abdel Shaheed, Christina ; Hayes, Christopher ; Maher, Christopher G. ; Ballantyne, Jane C. ; Underwood, Martin ; McLachlan, Andrew J. ; Martin, Jennifer H. ; Narayan, Sujita W. ; Sidhom, Mark A.

Pain is one of the most burdensome symptoms in people with cancer, and opioid analgesics are considered the mainstay of cancer pain management. For this review, the authors evaluated the efficacy and toxicities of opioid analgesics compared with placebo, other opioids, nonopioid analgesics, and nonpharmacologic treatments for background cancer pain (continuous and relatively constant pain present at rest), and breakthrough cancer pain (transient exacerbation of pain despite stable and [...]

Cet article présente une mise à jour des recommandations de la "Multinational Asssociation of Supportive Care in Cancer" et de l'"European Society for Medical Oncology" concernant la prévention et la prise en charge des nausées et vomissements induits par la chimiothérapie chez les patients atteints d'un cancer

2023 updated MASCC/ESMO consensus recommendations: prevention of nausea and vomiting following multiple-day chemotherapy, high-dose chemotherapy, and breakthrough nausea and vomiting

Rapoport, Bernardo Leon ; Herrstedt, Jørn ; Snow, Rebecca Clark ; Radhakrishnan, Venkatraman ; Saito, Mitsue ; Navari, Rudolph M. ; Smit, Teresa

Purpose: This review is an update of the MASCC/ESMO 2015 recommendations for the prophylaxis of acute and delayed nausea and vomiting induced by multiple-day chemotherapy, high-dose chemotherapy, and breakthrough nausea and vomiting. Methods: A systematic literature search was conducted using PubMed from June 1, 2015, through February 1, 2023. Results: We identified 56 references (16 were duplications or invalid), leaving 40 manuscripts for this search. The panel classified level I evidence [...]

A partir d'une revue de la littérature (79 articles), cette étude analyse la nature et l'efficacité des interventions destinées à améliorer la qualité de vie des patients atteints d'un cancer de la tête et du cou traité par radiothérapie

Interventions to improve quality of life in patients with head and neck cancers receiving radiation therapy: a scoping review

Nayak, Shalini Ganesh ; George, Anice ; Sharan, Krishna ; Nayak, Baby S. ; Salins, Naveen

Background: Quality of life (QOL) is impaired in patients with head and neck cancers (HNC) due to illness and treatment-associated morbidity. Although there is evidence from the studies on interventions’ role in improving QOL receiving radiation therapy, these are not systematically synthesised. In this scoping review, we searched and synthesised the evidence on interventions to improve the QOL and its impact among patients with HNCs. Methods: This scoping review was conducted using the [...]

Menée aux Etats-Unis à partir de données portant sur 6 938 patients atteints d'un cancer gastrique de stade localement avancé ayant été réséqué (âge moyen : 65,9 ans), cette étude de cohorte analyse la survie globale en fonction de l'origine ethnique et selon l'administration d'un traitement néoadjuvant

Survival Outcomes and Patterns of Care for Stage II or III Resected Gastric Cancer by Race and Ethnicity

Wu, S. Peter ; Keshavjee, Sara H. ; Yoon, Sam S. ; Kwon, Steve

Importance: Many multimodality treatment regimens exist for gastric adenocarcinoma, including neoadjuvant vs adjuvant chemotherapy, radiation, or both. Neoadjuvant therapy is recommended in the United States for patients with locally advanced gastric cancer; however, it is unknown whether the outcomes of neoadjuvant therapy are associated with race and ethnicity. Objective: To evaluate the differences in outcomes by race and ethnicity of patients with noncardia gastric cancer undergoing [...]

Menée aux Etats-Unis à partir de données portant sur 1 268 femmes ayant survécu à un cancer diagnostiqué entre 15 et 39 ans, cette étude analyse les complications lors de l'accouchement et pour le nourrisson (naissance avant terme, petit poids de naissance, etc.)

Risk of adverse birth outcomes after adolescent and young adult cancer

Anderson, Chelsea ; Baggett, Christopher D ; Engel, Stephanie M ; Getahun, Darios ; Cannizzaro, Nancy T ; Mitra, Sara ; Meernik, Clare ; Moy, Lisa M ; Laurent, Cecile A ; Zhou, Xi ; Xu, Lanfang ; Kwan, Marilyn L ; Wood, William A ; Luke, Barbara ; Chao, Chun R ; Kushi, Lawrence H ; Nichols, Hazel B

Background: Many women diagnosed with cancer as adolescents and young adults (AYAs, ages 15-39 years) want biological children after cancer but lack information on the potential impact of their cancer history on future reproductive outcomes. We investigated the risk of adverse birth outcomes among AYA cancer survivors. Methods: We identified insured women diagnosed with AYA breast cancer, thyroid cancer, gynecologic cancers, lymphoma, or melanoma from 2003 to 2016 in the state of North Carolina [...]

Menée en Norvège, cette étude de cohorte analyse le retour au travail et les conditions d'emploi pour les patients ayant survécu à un cancer

Return to work after cancer–the impact of working conditions: A Norwegian Register-based Study

Le, Giang Huong ; Hermansen, Åsmund ; Dahl, Espen

Purpose: The purpose of this study is to compare a cohort of cancer survivors with a cohort of cancer-free employees (1) with respect to employment prospects over a 15-year period and (2) with respect to the differential impact of working conditions on employment over this time period. Methods: The cancer cohort is retrieved from the Cancer Registry of Norway, while data on the non-cancer cohort are retrieved from register data managed by Statistics Norway. Job exposure matrices were used to [...]

Menée à partir de données 2010-2019 d'une base nationale américaine portant sur 20 298 patients atteints d'un carcinome épidermoïde oropharyngé lié au papillomavirus humain (HPV), cette étude analyse les traitements reçus et la survie en fonction du lieu de soin (centre communautaire ou universitaire de cancérologie)

Increasing radiation therapy and lower survival for human papillomavirus–related oropharynx cancer associated with a shift to community cancer center care

Trakimas, Danielle R ; Mydlarz, Wojtek ; Mady, Leila J ; Koch, Wayne ; Quon, Harry ; London, Nyall R, Jr ; Fakhry, Carole

Studies have shown lower overall survival for patients with head and neck cancer treated at low-volume or community cancer centers. As the incidence of human papillomavirus (HPV)–related oropharyngeal squamous cell carcinoma steadily rises in the United States, we hypothesized that a greater proportion of patients with HPV-related oropharyngeal squamous cell carcinoma is being treated at community cancer centers, with a shift toward primary nonsurgical treatment.This cohort study included [...]

Mené sur 84 patients ayant survécu à un cancer colorectal et en détresse psychologique, cet essai randomisé évalue l'efficacité, pour réduire la sévérité de leur détresse, d'une intervention de psychothérapie proposant des entretiens en face à face, des sessions téléphoniques et un accès à un site web interactif

Randomized controlled trial of an individual blended cognitive behavioral therapy to reduce psychological distress among distressed colorectal cancer survivors: The COloRectal canceR distrEss reduCTion trial

Custers, José A. E. ; Kwakkenbos, Linda ; Levis, Brooke ; Döking, Sarah ; van der Hoeven, Yvonne C. W. ; Leermakers, Lynn ; de Wilt, Johannes H. W. ; Thewes, Belinda ; Braamse, Annemarie M. J. ; Dekker, Joost ; Prins, Judith B.

Objective: Colorectal cancer survivors (CRCS) often experience high levels of distress. The objective of this randomized controlled trial was to evaluate the effect of blended cognitive behavior therapy (bCBT) on distress severity among distressed CRCS. Methods: CRCS (targeted N = 160) with high distress (Distress Thermometer ≥5) between 6 months and 5 years post cancer treatment were randomly allocated (1:1 ratio) to receive bCBT, (14 weeks including five face-to-face, and three telephone [...]

Menée aux Etats-Unis par enquête auprès de 2 684 adultes, cette étude analyse leurs connaissances concernant l'association entre une infection par le papillomavirus humain et le cancer de l'anus

Awareness of the causal association between human papillomavirus and anal cancer among US adults

Atarere, Joseph ; Chido-Amajuoyi, Onyema ; Onyeaka, Henry ; Akpoviroro, Ogheneyoma ; Adewunmi, Comfort ; Mele, Ange Ahoussougbemey ; Faith, Chilota O. ; Nwani, Somtochi ; Kanth, Priyanka

Purpose: The incidence of anal cancer is on the rise in the US, especially among high-risk groups. This study examined the prevalence and determinants of awareness of the causal relationship between HPV and anal cancer among US adults. Methods: Study data was obtained from the 2017 to 2020 iterations of the Health Information National Trends Survey. The prevalence of awareness that HPV causes anal cancer was estimated among HINTS respondents who were aware of HPV in general. Survey weights were [...]

A partir d'une revue systématique de la littérature publiée jusqu'en juillet 2023 (59 études incluant un total de 134 287 patients), cette méta-analyse évalue l'effet, sur la survie globale des patients atteints d'un cancer, des réunions de concertations pluridisciplinaires dans la prise de décision partagée

The Impact of Multidisciplinary Cancer Conferences on Overall Survival: A Meta-Analysis

Huang, Ryan S ; Mihalache, Andrew ; Nafees, Abdulwadud ; Hasan, Asad ; Ye, Xiang Y ; Liu, Zhihui ; Leighl, Natasha B ; Raman, Srinivas

Background: Multidisciplinary cancer conferences (MCCs) are comprised of regular meetings between diverse specialists working together to share clinical decision making in cancer care. The aim of this study is to systematically review and meta-analyze the effect of MCC intervention on overall survival of cancer patients. Methods: A systematic literature search was conducted on Ovid MEDLINE, EMBASE and the Cochrane Controlled Register of Trials for studies published up to July 2023. Studies [...]