A partir d'une revue systématique de la littérature (6 articles), cette étude analyse les outils d'évaluation des besoins en soins de support déclarés par les aidants familiaux de patients atteints d'un cancer et recevant des soins palliatifs

Needs assessment instruments for family caregivers of cancer patients receiving palliative care: a systematic review

Cheng, Qinqin ; Xu, Binbin ; Ng, Marques S. N. ; Zheng, Hongling ; So, Winnie K. W.

Purpose : Family caregivers of palliative cancer patients experience various supportive care needs. Appropriate self-reported instruments with robust psychological properties are required to identify these needs of family caregivers. Therefore, we conducted a systematic review to identify self-reported supportive care needs assessment instruments for family caregivers of palliative cancer patients and assess their contents, psychometric properties, and applicability. Methods : Systematic [...]

Menée à partir de données portant sur 107 patients atteints d'un cancer hématologique, cette étude rétrospective analyse leurs déficiences fonctionnelles et leur qualité de vie après une greffe de cellules souches hématopoïétiques

The immediate impact of physical function and quality of life after hematopoietic stem cell transplantation

Lee, Yeji ; Kim, Inho ; Koh, Youngil ; Shin, Dongyeop ; Hong, Junshik ; Lee, Chang Won ; Seo, Kwan Sik

Purpose : Although hematopoietic stem cell transplantation (HSCT) is a curative treatment for hematologic malignancies, HSCT survivors often experience declined physical function and quality of life (QoL). However, the physical function and QoL changes in acute post-transplant patients remain unclear. This study aimed to investigate the impact of HSCT on physical function. Method : This retrospective control study included 107 HSCT patients. Physical function was evaluated weekly from admission [...]

Menée aux Etats-Unis à partir de données portant sur 938 adolescents et jeunes adultes atteints d'un sarcome diagnostiqué entre 2008 et 2016 (âge : 10-26 ans), cette étude de cohorte analyse la persistance d'une utilisation d'opioïdes dans l'année suivant les traitements anticancéreux

New persistent opioid use among adolescents and young adults with sarcoma

Beauchemin, Melissa P. ; Raghunathan, Rohit R. ; Accordino, Melissa K. ; Cogan, Jacob C. ; Kahn, Justine M. ; Wright, Jason D. ; Hershman, Dawn L.

Background : Adolescents and young adults (AYA) with sarcoma experience both acute and chronic pain related to their disease and treatment. Studies in older adults have reported a high risk of persistent opioid use after cancer therapy among previously opioid-naive patients; however, few studies have evaluated posttreatment opioid use among AYAs. This article describes patterns of new persistent opioid use among AYAs in the year after treatment for sarcoma. Methods : Opioid-naive patients who [...]

Menée à l'aide de données 1960-2018 de registres norvégiens portant sur 4 295 pompiers, cette étude analyse l'incidence des cancers et la mortalité associée

Comparison of cancer incidence and mortality in the Norwegian Fire Departments Cohort, 1960–2018

Marjerrison, Niki ; Jakobsen, Jarle ; Demers, Paul A ; Grimsrud, Tom K ; Hansen, Johnni ; Martinsen, Jan Ivar ; Nordby, Karl-Christian ; Veierød, Marit B ; Kjærheim, Kristina

Objectives: Elevated risk of cancer at several sites has been reported among firefighters, although with mixed findings. The purpose of this study was to calculate standardised incidence ratios (SIRs) and standardised mortality ratios (SMRs) for cancer and compare them to assess whether use of the different measures could be a source of inconsistencies in findings. Methods: The Norwegian Fire Departments Cohort, comprising 4295 male employees who worked at 15 fire departments across Norway, was [...]

Menée à partir des données 1993-2013 des registres américains des cancers et de la base Medicare portant sur 1 229 443 patients âgés atteints d'un cancer (âge : 67-99 ans), cette étude analyse l'association entre la présence de maladies liées à un dysfonctionnement du système immunitaire et la mortalité par cancer

Immune-related conditions and cancer-specific mortality among older adults with cancer in the United States

Wang, Jeanny H. ; Derkach, Andriy ; Pfeiffer, Ruth M. ; Engels, Eric A.

Immunity may play a role in preventing cancer progression. We studied associations of immune-related conditions with cancer-specific mortality among older adults in the United States. We evaluated 1,229,443 patients diagnosed with 20 common cancer types (age 67-99, years 1993-2013) using Surveillance Epidemiology and End Results-Medicare data. With Medicare claims, we ascertained immune-related medical conditions diagnosed before cancer diagnosis (4 immunosuppressive conditions [n=3380 affected [...]

Menée aux Etats-Unis à partir de données 1999-2014 portant sur 2 050 patients âgés ayant survécu à un cancer (âge: supérieur ou égal à 60 ans) et sur 9 474 personnes âgées sans antécédent de cancer, cette étude analyse l'association entre des fragilités et la mortalité

Frailty and risk of mortality in older cancer survivors and adults without a cancer history: Evidence from the National Health and Nutrition Examination Survey, 1999-2014

Zhang, Dongyu ; Mobley, Erin M. ; Manini, Todd M. ; Leeuwenburgh, Christiaan ; Anton, Stephen D. ; Washington, Caretia J. ; Zhou, Daohong ; Parker, Alexander S. ; Okunieff, Paul G. ; Bian, Jiang ; Guo, Yi ; Pahor, Marco ; Hiatt, Robert A. ; Braithwaite, Dejana

BACKGROUND : Epidemiologic evidence reporting the role of frailty in survival among older adults with a prior cancer diagnosis is limited. METHODS : A total of 2050 older adults (≥60 years old) surviving for at least 1 year after a cancer diagnosis and 9474 older adults without a cancer history from the National Health and Nutrition Examination Survey (1999-2014) were included for analysis. The exposure variable, a 45-item frailty index (FI), was categorized on the basis of validated cutoffs [...]

Menée à partir de données de 7 études américaines portant sur un total de 4 337 patientes atteintes d'un cancer epithélial de l'ovaire, cette étude analyse la survie en fonction de l'origine ethnique

Racial disparities in epithelial ovarian cancer survival: An examination of contributing factors in the Ovarian Cancer in Women of African Ancestry (OCWAA) consortium

Harris, Holly R. ; Guertin, Kristin A. ; Camacho, Tareq F ; Johnson, Courtney E. ; Wu, Anna H. ; Moorman, Patricia G. ; Myers, Evan ; Bethea, Traci N. ; Bandera, Elisa V. ; Joslin, Charlotte E. ; Ochs-Balcom, Heather M. ; Peres, Lauren C. ; Rosenow, Will T. ; Setiawan, Veronica W. ; Beeghly-Fadiel, Alicia ; Dempsey, Lauren F. ; Rosenberg, Lynn ; Schildkraut, Joellen M.

Black women diagnosed with epithelial ovarian cancer have poorer survival compared to White women. Factors that contribute to this disparity, aside from socioeconomic status and guideline-adherent treatment, have not yet been clearly identified. We examined data from the Ovarian Cancer in Women of African Ancestry (OCWAA) consortium which harmonized data on 1,074 Black women and 3,263 White women with ovarian cancer from seven U.S. studies. We selected potential mediators and confounders by [...]

Menée aux Etats-Unis à partir de données portant sur 404 patientes âgées ayant survécu à un cancer du sein et sur 2 020 témoins (âge : supérieur ou égal à 65 ans), cette étude analyse l'évolution de leurs déficiences cognitives depuis le diagnostic de la maladie

Long-term changes of cognitive impairment among older breast cancer survivors

Luo, Juhua ; Schousboe, John T. ; Ensrud, Kristine E. ; Hendryx, Michael

Purpose : Cancer-related cognitive impairment is common during cancer treatment; however, it is unclear whether the impairment persists over time. Our study aimed to examine long-term cognitive impairment among older breast cancer survivors. Methods : Participants included 2420 community-dwelling women aged 65 years or older at enrollment (1986–1988) (404 breast cancer cases and 1:5 matched cancer-free controls) from the Study of Osteoporotic Fractures. Participants were followed for 20 years [...]

A partir d'une revue systématique de la littérature (16 études), cette méta-analyse évalue les effets de soins palliatifs précoces chez des patients atteints d'un cancer incurable

Effects of early palliative care on patients with incurable cancer: A meta-analysis and systematic review

Huo, Bingjie ; Song, Yanru ; Chang, Liang ; Tan, Bibo

Objective : This meta-analysis aims to compare the effects of early palliative care on patients with incurable cancer with those of standard oncologic care or on-demand palliative care. Methods : Pubmed, Embase, Web of Science, Cochrane Library, ClinicalTrials.gov and World Health Organization International Clinical Trials Registry Platform (ICTRP) were searched for relevant randomised controlled trials. We also screened reference lists of included studies for additional qualified studies. We [...]

Menée en Angleterre à partir de données portant sur 10 966 patientes atteintes d'un cancer du sein diagnostiqué entre 1995 et 2017 et décédées entre 2014 et 2017, cette étude de cohorte analyse l'association entre l'utilisation d'une chimiothérapie palliative dans les 2 années précédant le décès, les hospitalisations non programmées et le lieu du décès

Palliative chemotherapy for breast cancer: A population-based cohort study of emergency hospital admissions and place of death

Bright, Chloe J. ; Dunlop, Casey ; Chen, Cong ; Smittenaar, Rebecca ; McPhail, Sean ; Hanbury, Georgina ; Dodwell, David ; Pritchard-Jones, Kathy ; Peake, Mick ; Kipps, Emma

Objective : Patients with incurable breast cancer may be treated with chemotherapy to improve cancer-related symptoms, quality of life and survival. We examined the association between use of palliative chemotherapy towards the end of life in breast cancer patients and outcomes including unplanned hospital admission and place of death. Methods : A total of 10,966 women, treated with palliative chemotherapy for breast cancer (diagnosed 1995–2017 in England) within the 2 years prior to death [...]