A partir d'une revue systématique de la littérature publiée entre 2010 et 2018, cette étude présente les recommandations mises à jour de l'"American Society of Clinical Oncology" et de l'"American Society of Hematology" concernant l'utilisation d'agents stimulant l'érythropoïèse pour traiter une anémie chez des patients atteints d'un cancer

Management of Cancer-Associated Anemia With Erythropoiesis-Stimulating Agents: ASCO/ASH Clinical Practice Guideline Update

Julia Bohlius ; Kari Bohlke ; Roberto Castelli ; Benjamin Djulbegovic ; Maryam B. Lustberg ; Massimo Martino ; Giannis Mountzios ; Namrata Peswani ; Laura Porter ; Tiffany N. Tanaka ; Gianluca Trifirò ; Hushan Yang ; Alejandro Lazo-Langner

PURPOSE : To update the American Society of Clinical Oncology (ASCO)/American Society of Hematology (ASH) recommendations for use of erythropoiesis-stimulating agents (ESAs) in patients with cancer. METHODS : PubMed and the Cochrane Library were searched for randomized controlled trials (RCTs) and meta-analyses of RCTs in patients with cancer published from January 31, 2010, through May 14, 2018. For biosimilar ESAs, the literature search was expanded to include meta-analyses and RCTs in [...]

Mené sur 160 patients ayant survécu à un cancer, cet essai randomisé compare l'intérêt d'une intervention à base d'acupuncture et d'une psychothérapie comportementale pour réduire la sévérité de l'insomnie, diminuer la douleur et la fatigue, et améliorer la qualité de vie

Acupuncture Versus Cognitive Behavioral Therapy for Insomnia in Cancer Survivors: A Randomized Clinical Trial

Garland, Sheila N ; Xie, Sharon X ; DuHamel, Kate ; Kantoff, Philip ; Bao, Ting ; Mao, Jun J ; Li, Qing ; Song, Sarah ; Barg, Frances K ; Gehrman, Philip

Background : Insomnia is a common and debilitating disorder experienced by cancer survivors. While cancer survivors expressed interest in using non-pharmacological treatment to manage insomnia, the comparative effectiveness between acupuncture and Cognitive Behavioral Therapy for Insomnia (CBT-I) for this disorder is unknown. Methods : This randomized trial compared 8 weeks of acupuncture (n = 80) and CBT-I (n = 80) in cancer survivors. Acupuncture involved stimulating specific points on the [...]

Menée aux Etats-Unis à partir de données portant sur des individus âgés de 25 à 74 ans, cette étude analyse l'évolution, sur la période 2000-2015, de la mortalité par cancer du foie, en fonction du niveau socioéconomique et de la présence d'une infection par le virus de l'hépatite C

Temporal trends in liver cancer mortality by educational attainment in the United States, 2000-2015

Ma, Jiemin ; Siegel, Rebecca L. ; Islami, Farhad ; Jemal, Ahmedin

Background : Liver cancer is the most rapidly rising cause of cancer death in the United States. However, it is unclear whether the mortality trend differs by socioeconomic and/or hepatitis C virus (HCV) infection status. Methods : Joinpoint analyses and Poisson regression modeling were performed to examine trends in death rates from liver cancer by education and HCV infection status among persons aged 25 to 74 years from 2000 to 2015. Disparities in liver cancer mortality were measured as a [...]

Menée aux Etats-Unis par enquête auprès de 4 680 patients ayant survécu à un cancer, cette étude analyse l'association entre l'utilisation de la cigarette électronique et l'utilisation de la cigarette classique

Associations between e-cigarette and combustible cigarette use among U.S. cancer survivors: implications for research and practice

Antwi, Godfred O. ; Lohrmann, David K. ; Jayawardene, Wasantha ; Chow, Angela ; Obeng, Cecilia S. ; Sayegh, Aaron M.

Purpose : Prior studies established significant associations between e-cigarette use and combustible cigarette smoking in the general population; however, little is known about such associations among cancer survivors. Thus, the current study examined possible associations between e-cigarette use and combustible cigarette smoking among U.S. cancer survivors. Methods : Cross-sectional data were drawn from the 2016 Behavioral Risk Factor Surveillance System Survey. Binary logistic regression was [...]

Menée à partir des données des registres américains des cancers portant sur 83 086 patientes atteintes d'un cancer du sein ou de l'ovaire (âge : 20 ans ou plus), cette étude analyse l'utilisation de tests génétiques et évalue la prévalence de variants génétiques pathogènes pouvant constituer une cible thérapeutique

Genetic Testing and Results in a Population-Based Cohort of Breast Cancer Patients and Ovarian Cancer Patients

Kurian, Allison W. ; Ward, Kevin C. ; Howlader, Nadia ; Deapen, Dennis ; Hamilton, Ann S. ; Mariotto, Angela ; Miller, Daniel ; Penberthy, Lynne S. ; Katz, Steven J.

PURPOSE : Genetic testing for cancer risk has expanded rapidly. We examined clinical genetic testing and results among population-based patients with breast and ovarian cancer. METHODS : The study included all women 20 years of age or older diagnosed with breast or ovarian cancer in California and Georgia between 2013 and 2014 and reported to the SEER registries covering the entire state populations. SEER data were linked to results from four laboratories that performed nearly all germline [...]

Menée aux Etats-Unis à partir de données portant sur 152 patientes atteintes d'un cancer de l'ovaire, cette étude de cohorte analyse l'évolution de la polypharmacie sur une période allant du diagnostic jusqu'à 2 ans après les traitements anticancéreux

Polypharmacy in Patients with Ovarian Cancer

Oldak, Sean ; Ioannou, Stephanie ; Kamath, Priyanka ; Huang, Marilyn ; George, Sophia ; Slomovitz, Brian ; Schlumbrecht, Matthew

Polypharmacy has been associated with morbidity and mortality in patients with cancer. Data about polypharmacy among patients with ovarian cancer are limited. The primary objective of this study was to evaluate polypharmacy in a cohort of patients with ovarian cancer and to assess the evolution of polypharmacy from initial presentation to 2 years posttreatment. A secondary objective was to evaluate differences in polypharmacy between a subset of patients primarily treated in our comprehensive [...]

A partir d'une revue systématique de la littérature publiée jusqu'en février 2018 (18 études de cohortes prospectives), cette méta-analyse évalue l'association entre une activité physique, avant ou après le diagnostic, et la mortalité, chez des patients atteints d'un cancer colorectal

Physical activity and mortality in patients with colorectal cancer: a meta-analysis of prospective cohort studies

Qiu, Shumin ; Jiang, Chongmin ; Zhou, Lin

The association between physical activity (PA) and colorectal cancer (CRC) patients’ survival is inconsistent. We conducted a systematic review and meta-analysis to summarize published articles on this issue. We performed a comprehensive search of the PubMed, Embase, and Web of Science databases for relevant articles through 28 February 2018. The summary hazard ratios (HRs) and 95% confidence intervals (CIs) were estimated using a random-effects model. Eighteen prospective cohort studies were [...]

A partir d'une revue systématique de la littérature publiée jusqu'en janvier 2018 (23 études), cette étude analyse les caractéristiques associées à l'utilisation des services de santé chez des patientes ayant survécu à un cancer du sein

Health care services use among long-term breast cancer survivors: a systematic review

Jansana, Anna ; Posso, Margarita ; Guerrero, Inmaculada ; Prados-Torres, Alexandra ; Del Cura, Maria Isabel ; Castells, Xavier ; Sala, Maria

Purpose : Long-term breast cancer survivors are women surviving at least 5 years after diagnosis. This systematic review aimed to summarize the main characteristics and patterns of healthcare service use (frequency of visits, health providers visited, and preventive care performed) among long-term breast cancer survivors. Methods : We used standard Cochrane Collaboration methods and searched the MEDLINE and EMBASE databases up to January 2018. We included English language observational studies [...]

A partir d'une revue systématique de la littérature, cette étude analyse les caractéristiques démographiques, les traitements reçus et la survie associée chez des patients atteints d'une tumeur maligne de la trachée (733 cas)

Demography, patterns of care and survival outcomes in patients with malignant tumors of trachea: A systematic review and individual patient data analysis of 733 patients

Mallick, Supriya ; Benson, Rony ; Giridhar, Prashanth ; Rajan Singh, Angel ; Rath, Goura K.

Background : Malignant tumors of the trachea (MTT) account for 0.01-0.4% of all cancer cases. The rarity of the tumor along with different histologies makes it is a great challenge on how to optimally treat tracheal tumors and most of the available data is from small retrospective data series. We performed a systematic review and individual patient data analysis to evaluate the patterns of care and survival outcomes in patient with MTT. Methodology : A comprehensive search in Pub Med and Google [...]

Menée aux Etats-Unis auprès de 1 436 patients atteints d'un cancer ou ayant survécu à la maladie, cette étude analyse l'efficacité d'un outil permettant d'évaluer le risque de dépression et d'anxiété et de détecter une détresse psychologique

CancerSupportSource: validation of a revised multi-dimensional distress screening program for cancer patients and survivors

Buzaglo, Joanne S. ; Zaleta, Alexandra K. ; McManus, Shauna ; Golant, Mitch ; Miller, Melissa F.

Purpose : To facilitate access to and provision of psychosocial care to cancer patients in the community, the Cancer Support Community (CSC) developed CancerSupportSource® (CSS), an evidence-based psychosocial distress screening program. The current study examined the psychometric properties and multi-dimensionality of a revised 25-item version of CSS, and evaluated the scale’s ability to identify individuals at risk for clinically significant levels of depression and anxiety. Methods : CSS [...]

A partir d'une revue systématique de la littérature (7 études, 241 cas et 273 témoins), cette méta-analyse évalue les capacités cognitives chez des patients ayant survécu à un cancer de la thyroïde

Cognitive functioning in thyroid cancer survivors: a systematic review and meta-analysis

Saeed, Omar ; Bernstein, Lori J. ; Fazelzad, Rouhi ; Samuels, Mary ; Burmeister, Lynn A. ; Thabane, Lehana ; Ezzat, Shereen ; Goldstein, David P. ; Jones, Jennifer ; Sawka, Anna M.

Background : Some thyroid cancer (TC) survivors experience cognitive symptoms. Purpose : The purpose of this study is to perform a systematic literature review and meta-analysis comparing cognitive performance in TC survivors to controls. Methods : We performed a seven-database electronic search and hand-search. We performed duplicate independent reviews and data abstraction. Random effects meta-analyses reported standardized mean differences (SMDs) with 95% confidence intervals (CIs), where a [...]

A partir d'une revue systématique de la littérature publiée entre janvier 2000 et janvier 2019 (35 articles), cette étude analyse l'effet, sur la situation socioéconomique des parents, d'un diagnostic de cancer chez l'enfant

The impact of childhood cancer on parents´ socio-economic situation - a systematic review

Roser, Katharina ; Erdmann, Friederike ; Michel, Gisela ; Falck Winther, Jeanette ; Mader, Luzius

Objective : Taking care of children diagnosed with cancer may have considerable consequences on parents´ socio‐economic situation. Our systematic review aimed to evaluate and synthesize the evidence on the impact of childhood cancer on parents´ socio‐economic situation. Methods : Systematic literature searches for articles published between January 2000 and January 2019 were performed in PubMed, Scopus, and PsycINFO. Findings of eligible articles were narratively synthesized and quality [...]

Menée aux Etats-Unis à partir de données portant sur 1 500 000 patients atteints d'un cancer, cette étude analyse, sur la période 2006-2015, l'évolution du nombre de visites aux urgences pour des complications liées aux radiothérapies ou aux traitements systémiques, identifie la nature des complications puis évalue les coûts associés

Treatment-Related Complications of Systemic Therapy and Radiotherapy

Jairam, Vikram ; Lee, Victor ; Park, Henry S. ; Thomas, Charles R., Jr ; Melnick, Edward R. ; Gross, Cary P. ; Presley, Carolyn J. ; Adelson, Kerin B. ; Yu, James B.

Importance : Systemic therapy and radiotherapy can be associated with acute complications that may require emergent care. However, there are limited data characterizing complications and the financial burden of cancer therapy that are treated in emergency departments (EDs) in the United States. Objectives : To estimate the incidence of treatment-related complications of systemic therapy or radiotherapy, examine factors associated with inpatient admission, and investigate the overall financial [...]

Menée aux Etats-Unis à partir de données d'une enquête nationale, cette étude analyse l'utilisation de médecines complémentaires et alternatives chez des patients atteints d'un cancer ou ayant survécu à la maladie

Prevalence and Nondisclosure of Complementary and Alternative Medicine Use in Patients With Cancer and Cancer Survivors in the United States

Sanford, Nina N. ; Sher, David J. ; Ahn, Chul ; Aizer, Ayal A. ; Mahal, Brandon A.

Complementary and alternative medicines (CAMs), defined as therapies used in addition to or instead of conventional therapies, respectively, are frequently used in the United States by patients with cancer and cancer survivors; however, there is concern that these individuals may not disclose CAM use to their physicians. A recently published report from the National Cancer Database found that a small subset of patients who reported CAM use (n = 258; 0.01% of the study population) had worse [...]