Menée au Royaume-Uni, cette étude évalue la part des mélanomes cutanés malins attribuable à une exposition solaire dans un contexte professionnel pour l'année 2011

The burden of occupationally-related cutaneous malignant melanoma in Britain due to solar radiation

Rushton, Lesley ; Hutchings, Sally J.

Background: Increasing evidence highlights the association of occupational exposure and cutaneous malignant melanoma (CMM). We estimated the burden of CMM and total skin cancer burden in Britain due to occupational solar radiation exposure. Methods: Attributable fractions (AF) and numbers were estimated for CMM mortality and incidence using risk estimates from the published literature and national data sources for proportions exposed. We extended existing methods to account for the exposed [...]

Menée en Finlande, Islande, Norvège et Suède auprès de 113 343 patients atteints d'un cancer de la vessie et de 566 715 témoins sur la période 1961-2005, cette étude évalue l'association entre une exposition professionnelle à divers solvants et le risque de développer la maladie

Occupational exposure to solvents and bladder cancer: A population-based case control study in Nordic countries

Hadkhale, Kishor ; Martinsen, Jan Ivar ; Weiderpass, Elisabete ; Kjaerheim, Kristina ; Sparén, Pär ; Tryggvadottir, Laufey ; Lynge, Elsebeth ; Pukkala, Eero

The objective of the study was to assess the relationship between exposure to selected solvents and the risk of bladder cancer. This study is based on the Nordic Occupational Cancer (NOCCA) database and comprises 113,343 cases of bladder cancer diagnosed in Finland, Iceland, Norway and Sweden between 1961 and 2005 and 566,715 population controls matched according to country, sex and birth year. Census-based occupational titles of the cases and controls were linked with the job exposure matrix [...]

Menée au Canada à partir de données portant sur 496 patientes atteintes d'un cancer de l'ovaire et sur 908 témoins, cette étude évalue l'association entre des facteurs hormonaux (utilisation d'une contraception orale), des facteurs reproductifs et le risque de développer la maladie

Hormonal and reproductive factors and the risk of ovarian cancer

Koushik, Anita ; Grundy, Anne ; Abrahamowicz, Michal ; Arseneau, Jocelyne ; Gilbert, Lucy ; Gotlieb, Walter H. ; Lacaille, Julie ; Mes-Masson, Anne-Marie ; Parent, Marie-Élise ; Provencher, Diane M. ; Richardson, Lesley ; Siemiatycki, Jack

Purpose : Hormone-related factors have been associated with ovarian cancer, the strongest being parity and oral contraceptive use. Given reductions in birth rates and increases in oral contraceptive use over time, associations in more recent birth cohorts may differ. Furthermore, consideration of ovarian cancer heterogeneity (i.e., Type I/II invasive cancers) may contribute to a better understanding of etiology. We examined hormone-related factors in relation to ovarian cancer risk overall, for [...]

Menée en Norvège à partir de données médicales portant sur 1 353 724 participantes nées entre 1960 et 1996, cette étude évalue l'association entre un recours à des techniques de procréation médicalement assistée, une utilisation de traitements pour la fertilité et le risque de cancer, en fonction du nombre d'accouchements

Cancer Risk in Women Treated with Fertility Drugs According to Parity status - A Registry-based Cohort Study

Reigstad, Marte M ; Storeng, Ritsa ; Myklebust, Tor A. ; Oldereid, Nan B ; Omland, Anne K ; Robsahm, Trude E ; Brinton, Louise A. ; Vangen, Siri ; Furu, Kari ; Larsen, Inger K

Background : Long-term safety of assisted reproductive techniques (ART) is of interest as use is increasing. Cancer risk is known to be affected by parity. This study examined risk of cancer after fertility treatment, stratified by women's parity. Methods : Data was obtained on all women (n=1 353 724) born in Norway between 1960-1996. Drug exposure data (2004-2014) was obtained from the Norwegian Prescription Database [drugs used in ART and clomiphene citrate (CC)]. The Medical Birth Registry [...]

A partir d'une revue systématique de la littérature (24 études cas-témoins, 3 études de cohorte, 302 705 patientes), cette méta-analyse évalue l'association entre une utilisation de talc sur la zone génitale et le risque de développer un cancer de l'ovaire

Genital use of talc and risk of ovarian cancer: a meta-analysis

Berge, Wera ; Mundt, Kenneth ; Luu, Hung ; Boffetta, Paolo

Some epidemiological studies suggest an association between genital use of talc powders and increased risk of ovarian cancer, but the evidence is not consistent. We performed a meta-analysis of epidemiological studies to formally evaluate this suspected association. A systematic search was conducted in Medline, Embase, and Scopus, leading to the identification of 24 case-control studies and three cohort studies, including 302 705 women with ovarian cancer. In the meta-analysis, we used a [...]

Menée aux Etats-Unis à partir de données portant sur 222 019 participantes âgées de 35 à 74 ans, cette étude évalue l'association entre des antécédents familiaux de cancer du sein, la densité mammaire et le risque de développer un cancer du sein (2 456 cas de cancer invasif du sein)

Family history of breast cancer, breast density, and breast cancer risk in a U.S. breast cancer screening population

Ahern, Thomas P. ; Sprague, Brian L. ; Bissell, Michael C.S. ; Miglioretti, Diana L. ; Buist, Diana S.M. ; Braithwaite, Dejana ; Kerlikowske, Karla

Background: The utility of incorporating detailed family history into breast cancer risk prediction hinges on its independent contribution to breast cancer risk. We evaluated associations between detailed family history and breast cancer risk while accounting for breast density. Methods: We followed 222,019 participants aged 35-74 in the Breast Cancer Surveillance Consortium, of whom 2,456 developed invasive breast cancer. We calculated standardized breast cancer risks within joint strata of [...]

Menée aux Etats-Unis à partir de données portant sur 103 721 participantes âgées de 45 à 75 ans dont 14 558 patientes diabétiques, cette étude évalue les disparités ethniques dans l'association entre un diabète de type 2, une obésité et le risque de cancer du sein (6 692 cas, durée médiane de suivi : 14,8 ans)

Type 2 Diabetes, Obesity, and Breast Cancer Risk: The Multiethnic Cohort

Maskarinec, Gertraud ; Jacobs, Simone ; Park, Song-Yi ; Haiman, Christopher A. ; Setiawan, Veronica Wendy ; Wilkens, Lynne R. ; Le Marchand, Loic

Background: Obesity has been more consistently associated with breast cancer than type 2 diabetes (T2D). This analysis examined the combination of the two factors in the Multiethnic Cohort (MEC). Methods: Women aged 45-75 years entered the MEC in 1993-1996 by completing a questionnaire. T2D status was self-reported at baseline, two follow-up questionnaires, and confirmed by administrative data. Cancers were identified from tumor registries and deaths through vital records until 2010. Cox [...]

A partir des données des registres américains des cancers et de la base Medicare portant sur des patientes âgées de plus de 66 ans sur la période 1992-2011, cette étude évalue l'association entre un diabète, un taux de glycémie anormal, une dyslipidémie, une hypertension et le risque de cancer du sein inflammatoire et d'autres types de cancers du sein en fonction du stade la tumeur au diagnostic (209 929 cas et 200 00 témoins)

Diabetes, Abnormal Glucose, Dyslipidemia, Hypertension and Risk of Inflammatory and Other Breast Cancer

Schairer, Catherine ; Gadalla, Shahinaz M. ; Pfeiffer, Ruth M. ; Moore, Steven C. ; Engels, Eric A.

Background: Obesity has been associated with substantially higher risk of inflammatory breast cancer (IBC) than other breast cancer. Here, we assess whether comorbidities of obesity, namely diabetes, abnormal glucose, dyslipidemia, and hypertension, are differentially related to risk of inflammatory breast cancer and other breast cancers by tumor stage at diagnosis (localized/regional/distant/unstaged). Methods: We used linked SEER-Medicare data, with female breast cancer cases aged 66+ years [...]