Menée au Canada et en Australie auprès de 178 survivants d'un cancer du côlon, cette étude évalue l'association entre leur niveau d'activité physique, mesurée de façon objective avec un accéléromètre, et leur qualité de vie

Associations of objectively assessed physical activity and sedentary time with health-related quality of life among colon cancer survivors

Vallance, Jeff K. ; Boyle, Terry ; Courneya, Kerry S. ; Lynch, Brigid M.

BACKGROUND : The primary purpose of this study was to determine associations of accelerometer-assessed moderate- to vigorous-intensity physical activity (MVPA) and sedentary time with health-related quality of life (HRQoL) and physical function and well-being in colon cancer survivors. METHODS : Colon cancer survivors (N = 178) from Alberta, Canada (n = 92) and Western Australia (n = 86) completed a mailed survey that assessed HRQoL (Functional Assessment of Cancer Therapy–Colorectal), physical [...]

Menée en Chine auprès de 52 participants, cette étude cas-témoins analyse les effets à 6 mois d'une intervention à base de Tai Chi Qigong sur la vélocité de la circulation sanguine, l'activité cardiaque, la puissance maximale aérobie chez des survivants d'un cancer du rhinopharynx

Effects of a 6-month Tai Chi Qigong program on arterial hemodynamics and functional aerobic capacity in survivors of nasopharyngeal cancer

Fong, ShirleyS M. ; Ng, ShamayS M. ; Luk, W. S. ; Chung, JoanneW Y. ; Leung, JoyceC Y. ; Masters, RichS W.

Purpose : Survivors of nasopharyngeal cancer (NPC) often sustain cardiovascular complications after conventional cancer treatments. Tai Chi (TC) Qigong training may be a viable way to improve peripheral circulatory status and aerobic capacity in this population. The objective of this study was to evaluate the effects of a 6-month TC Qigong training program on blood flow velocities and resistance, palmar skin temperature, and functional aerobic capacity in survivors of NPC. Methods : Twenty-five [...]

Menée au Royaume-Uni par enquête auprès de 2 371 patients atteints d'un cancer (15 types différents), cette étude analyse les facteurs associés à une consultation tardive pour des symptômes associés au cancer et évalue l'impact de ces délais sur la survie

Risk factors for delay in symptomatic presentation: a survey of cancer patients

Forbes, L. J. L. ; Warburton, F. ; Richards, M. A. ; Ramirez, A. J.

Background: Delay in symptomatic presentation leading to advanced stage at diagnosis may contribute to poor cancer survival. To inform public health approaches to promoting early symptomatic presentation, we aimed to identify risk factors for delay in presentation across several cancers. Methods: We surveyed 2371 patients with 15 cancers about nature and duration of symptoms using a postal questionnaire. We calculated relative risks for delay in presentation (time from symptom onset to first [...]

A partir des données de l'Organisation Mondiale de la Santé, cette étude analyse l'évolution de la mortalité par cancer (20 localisations) en Amérique du Nord et dans onze pays d'Amérique latine, sur la période 1980-2010

Trends in mortality from major cancers in the Americas: 1980-2010

Chatenoud, L. ; Bertuccio, P. ; Bosetti, C. ; Malvezzi, M. ; Levi, F. ; Negri, E. ; La Vecchia, C.

Background : Between the 1970's and 2000 mortality in Latin America showed favorable trends for some common cancer sites, including stomach and male lung cancer in most countries. However, major concerns were related to mortality patterns from other cancers, particularly in women. We provide an up-to-date picture of patterns and trends in cancer mortality in Latin America. Methods : We analyzed data from the World Health Organization mortality database in 2005–2009 for 20 cancer sites in 11 [...]

Menée aux Etats-Unis auprès de 19 160 participants (âge moyen : 60 ans), cette étude de cohorte analyse l'association entre diverses comorbidités chroniques et le risque de neutropénie fébrile chez des patients atteints d'un cancer (lymphome non hodgkinien, sein, côlon-rectum, poumon, ovaire, estomac) et traités par chimiothérapie

History of chronic comorbidity and risk of chemotherapy-induced febrile neutropenia in cancer patients not receiving G-CSF prophylaxis

Chao, C. ; Page, J. H. ; Yang, S-J. ; Rodriguez, R. ; Huynh, J. ; Chia, V. M.

Background : Chemotherapy-induced febrile neutropenia (FN) is a clinically important complication that impacts patient outcome by delaying chemotherapy doses or reducing dose intensity. Risk of FN depends on chemotherapy- and patient-level factors. We sought to determine the effects of chronic comorbidities on risk of FN. Design : We conducted a cohort study to examine the association between a variety of chronic comorbidities and risk of FN in patients diagnosed with six types of cancer [...]

Menée en Suède auprès de 635 patientes atteintes d'un cancer épithélial de l'ovaire, cette étude de cohorte prospective évalue l'association entre le niveau socioéconomique et la survie des patientes

Socioeconomic status and epithelial ovarian cancer survival in Sweden

Weiderpass, Elisabete ; Oh, Jin-Kyoung ; Algeri, Sara ; Bellocco, Rino

Purpose : To investigate socioeconomic disparities in epithelial ovarian cancer (EOC) survival in Sweden. Methods : A cohort of 635 women with invasive EOC who participated in a nationwide population-based case–control study was included in the present population-based prospective study. Women were diagnosed with EOC between 1993 and 1995. Mortality until 31 December 2007 was determined through linkage with the Swedish Cause of Death Registry. Clinical data (tumor stage and tumor [...]

A partir des données de registres britanniques des cancers portant sur 28 733 patients atteints d'un cancer du poumon diagnostiqué entre 2006 et 2010, cette étude analyse les disparités socioéconomiques dans les traitements reçus

The role of patient, tumour and system factors in socioeconomic inequalities in lung cancer treatment: population-based study

Forrest, L. F. ; White, M. ; Rubin, G. ; Adams, J.

Background: Reducing socioeconomic inequalities in lung cancer treatment may reduce survival inequalities. However, the reasons for treatment variation are unclear. Methods: Northern and Yorkshire cancer registry, Hospital Episode Statistics and lung cancer audit data sets were linked. Logistic regression was used to explore the role of stage, histology, performance status and comorbidity in socioeconomic inequalities in lung cancer treatment, for 28 733 lung cancer patients diagnosed in [...]

Menée auprès de 164 patientes atteintes d'un cancer du sein HER2+, cette étude analyse l'association entre trois polymorphismes du gène MACC1 et la survie des patientes

Significant survival impact of MACC1 polymorphisms in HER2 positive breast cancer patients

Muendlein, Axel ; Hubalek, Michael ; Geller-Rhomberg, Simone ; Gasser, Klaus ; Winder, Thomas ; Drexel, Heinz ; Decker, Thomas ; Mueller-Holzner, Elisabeth ; Chamson, Martina ; Marth, Christian ; Lang, Alois H.

Background : Deregulation of hepatocyte growth factor (HGF)/mesenchymal-epithelial transition factor (MET) signalling has been associated with poor clinical outcome in breast cancer and other cancers. The recently discovered metastasis-associated in colon cancer-1 (MACC1) gene is a key regulator of the HGF/MET pathway. Potential links between genetic variants of the MACC1 gene and survival in breast cancer patients are unknown. In the present study, we therefore aimed to investigate the [...]

Menée au Royaume-Uni auprès de 7 064 patientes atteintes d'un cancer du sein (durée moyenne de suivi : 8,4 ans), cette étude analyse l'incidence de métastases osseuses ainsi que la survie

Incidence of bone metastases and survival after a diagnosis of bone metastases in breast cancer patients

Harries, M. ; Taylor, A. ; Holmberg, L. ; Agbaje, O. ; Garmo, H. ; Kabilan, S. ; Purushotham, A.

Background: Bone is the most common metastatic site associated with breast cancer. Using a database of women with breast cancer treated at Guy's Hospital, London 1976–2006 and followed until end 2010, we determined incidence of and survival after bone metastases Methods: We calculated cumulative incidence of bone metastases considering death without prior bone metastases as a competing risk. Risk of bone metastases was modelled through Cox-regression. Survival after bone metastases diagnosis [...]

Menée aux Etats-Unis auprès de 1 735 survivantes d'un cancer du sein invasif diagnostiqué entre 2008 et 2011 (âgées de 20 à 74 ans), cette étude analyse les disparités ethniques dans leurs pratiques d'activité physique

Racial differences in physical activity among breast cancer survivors: Implications for breast cancer care

Hair, Brionna Y. ; Hayes, Sandi ; Tse, Chiu-Kit ; Bell, Mary Beth ; Olshan, Andrew F.

BACKGROUND Physical activity after breast cancer diagnosis is associated with improved survival. The current study examined levels of and changes in physical activity after breast cancer diagnosis, overall and by race. METHODS Phase 3 of the Carolina Breast Cancer Study assessed both pre- and postdiagnosis physical activity levels in a cohort of 1735 women aged 20 years to 74 years who were diagnosed with invasive breast cancer between 2008 and 2011 in 44 counties of North Carolina. Logistic [...]

A partir d'une revue de la littérature (18 études), cette étude analyse les expériences de parents atteints d'un cancer de stade avancé et celles de leurs enfants adolescents

Adolescents living with a parent with advanced cancer: a review of the literature

Phillips, Farya

Objective : Families and children facing the death of a parent from cancer constitute a vulnerable population often overlooked by healthcare professionals and researchers. The purpose of this review is to provide a systematic analysis of the literature that examines the experiences of parents diagnosed with advanced cancer and their adolescent children. Methods : Reviews of quantitative, qualitative, and mixed method publications between 2000 and 2013 were selected in order to obtain the most [...]

Menée aux Etats-Unis auprès de 100 aidants de patients atteints de cancer et âgés de plus de 65 ans, cette étude analyse les facteurs associés à leurs difficultés dans l'assistance aux patients

Factors associated with high burden in caregivers of older adults with cancer

Hsu, Tina ; Loscalzo, Matthew ; Ramani, Rupal ; Forman, Stephen ; Popplewell, Leslie ; Clark, Karen ; Katheria, Vani ; Feng, Tao ; Strowbridge, Rex ; Rinehart, Redmond ; Smith, Dan ; Matthews, Keith ; Dillehunt, Jeff ; Hurria, Arti

BACKGROUND Older adults with cancer are vulnerable to functional decline, which places greater onus on caregivers. Few studies have prospectively examined burden in caregivers of older cancer patients. The objective of this study was to determine the factors associated with high caregiver burden. METHODS In total, 100 caregivers of patients aged ≥65 years with cancer, who were recruited at a single institution, completed questionnaires gauging their perception of the patient's physical, [...]

Menée aux Pays-Bas auprès de 325 patients atteints de cancer, cette étude longitudinale analyse l'association entre leurs caractéristiques médicales, leurs perceptions de la maladie et leurs façons d'y faire face

Illness perceptions of cancer patients: relationships with illness characteristics and coping

Hopman, Petra ; Rijken, Mieke

Objective : Illness perceptions have proven to be predictive of coping and adjustment in many chronically ill patients. However, insights into illness perceptions of cancer patients are scarce. The purpose of the present study was to explore how a heterogeneous sample of cancer patients perceive their illness. We also examined the relationships between cancer patients' illness perceptions, their illness characteristics, and their coping strategies. Methods : Participants were 325 cancer [...]

Menée en Suède auprès de 401 participants, cette étude de cohorte analyse les difficultés psychologiques rencontrées par les patients atteints de cancer après une œsophagectomie

Aspects of emotional functioning following oesophageal cancer surgery in a population-based cohort study

Hellstadius, Ylva ; Lagergren, Pernilla ; Lagergren, Jesper ; Johar, Asif ; Hultman, Christina M. ; Wikman, Anna

Objective : The aim of this study was to establish the proportion of patients reporting emotional problems following oesophagectomy for cancer and identify the risk characteristics for emotional problems. Methods : A Swedish population-based cohort study of patients with surgically treated oesophageal cancer was used. The European Organization for Research and Treatment of Cancer Quality of Life Questionnaire C30 was used to assess tension, worry, irritation and depressed mood at 6 months and [...]

Menée en Suède auprès de 280 patientes atteintes d'un cancer du sein récemment diagnostiqué, cette étude analyse leurs préoccupations relatives à leurs enfants et leurs besoins en soins de support de nature psychosociale

Worrying about one’s children after breast cancer diagnosis: desired timing of psychosocial intervention

Stinesen Kollberg, Karin ; Wilderäng, Ulrica ; Möller, Anders ; Steineck, Gunnar

Background : The purposes of this observational study were to analyze at what time point mothers desired psychosocial support regarding the worry about their children during the year after breast cancer diagnosis and to identify any psychosocial factors associated with this worry. Methods : In a population-based study, we analyzed data from 280 mothers diagnosed with breast cancer at Sahlgrenska University Hospital in Gothenburg, Sweden. Results : Of those who did not receive chemotherapy [...]

Menée aux Etats-Unis auprès de 722 survivantes d'un cancer du sein, cette étude analyse l'association entre leur statut marital, leur soutien social, leur degré d'optimisme et leur qualité de vie

Marital status and optimism score among breast cancer survivors

Croft, Lindsay ; Sorkin, John ; Gallicchio, Lisa

Purpose : There are an increasing number of breast cancer survivors, but their psychosocial and supportive care needs are not well-understood. Recent work has found marital status, social support, and optimism to be associated with quality of life, but little research has been conducted to understand how these factors relate to one another. Methods : Survey data from 722 breast cancer survivors were analyzed to estimate the association between marital status and optimism score, as measured [...]

Menée en Allemagne auprès de 104 patients atteints d'un cancer de la cavité buccale, cette étude analyse les caractéristiques personnelles associées à leurs capacités à faire face à la maladie

Coping with oral cancer: the impact of health and disease-related personality traits

Rana, Madiha ; Gellrich, Nils-Claudius ; Czens, Franziska ; Kanatas, Anastasios ; Rana, Majeed

Purpose : Oral tumours lead to critical reductions in quality of life and well being. Coping with illness is a multidimensional construct that is affected by various factors, including social structure, social support, locus of control and religious considerations. However, the effect of personality on coping with illness has hardly been studied. In this context, just one personality model has been developed, but this defines personality in very wide dimensions. Therefore, this study considered [...]

Menée aux Etats-Unis auprès de 13 630 patients atteints d'un cancer du poumon et de 3 198 patients atteints d'un cancer du côlon recevant une chimiothérapie, cette étude de cohorte rétrospective analyse le coût des soins liés à une anémie ou à une transfusion, après l'obligation introduite par la "Food and Drug Administration" de mentionner les risques associés à l'utilisation d'agents stimulant l'érythropoïèse

Costs of care for lung and colon cancer patients receiving chemotherapy following FDA policy changes

Stroupe, KevinT ; Tarlov, Elizabeth ; Weichle, ThomasW ; Zhang, QiuyingL ; Michaelis, LauraC ; Ozer, Howard ; Durazo-Arvizu, Ramon ; Hynes, DeniseM

Purpose : Use of erythropoiesis-stimulating agents (ESAs) in US cancer care declined amidst post-marketing evidence of adverse effects and the Food and Drug Administration’s (FDA) addition of a “black-box” warning to product labeling in March 2007. Because reduced ESA use may have led to more transfusions or increased anemia-related health care needs, we measured the policy’s impact on health care costs of lung and colon cancer patients receiving chemotherapy. Methods : In a retrospective [...]

A partir de données portant sur un échantillon représentatif de la population portugaise (35 229 participants âgés de plus de 15 ans), cette étude analyse l'état de santé, l'utilisation des soins de santé et les coûts financiers pour les survivants d'un cancer

Health status, use of healthcare, and socio-economic implications of cancer survivorship in Portugal: results from the Fourth National Health Survey

Pacheco-Figueiredo, Luís ; Lunet, Nuno

Purpose : Understanding the morbidity and socio-economic implications of cancer survivorship is essential for a comprehensive management of oncological diseases. We compared cancer survivors (CS) with the general population regarding health status, use of healthcare resources and socio-economic condition. Methods : We analyzed data from a representative sample of the Portuguese population aged ≥15 years (n = 35,229). We defined three groups of CS, according to the time since diagnosis and the [...]

Menée aux Etats-Unis auprès de 23 survivantes d'un cancer du sein et âgées de 52 à 83 ans, cette étude analyse leurs besoins pour résoudre les problèmes financiers posés par leur maladie

Dealing with the financial burden of cancer: perspectives of older breast cancer survivors

Pisu, Maria ; Martin, MichelleY ; Shewchuk, Richard ; Meneses, Karen

Purpose : Financial burden among cancer survivors is often overlooked in survivorship care planning. Cancer survivors with limited incomes may be particularly affected. Yet, little data are available to address financial issues among them. Eliciting the survivors’ perspectives on how to deal with this financial burden is a first crucial step to identifying the means to provide this supportive care. Methods : In this pilot study, three nominal group technique (NGT) sessions were conducted with a [...]

Menée au Japon auprès de 30 médecins oncologues, cette étude analyse les effets d'un programme de formation visant à développer leurs compétences en communication pour l'annonce de mauvaises nouvelles à leurs patients

Effect of Communication Skills Training Program for Oncologists Based on Patient Preferences for Communication When Receiving Bad News: A Randomized Controlled Trial

Fujimori, Maiko ; Shirai, Yuki ; Asai, Mariko ; Kubota, Kaoru ; Katsumata, Noriyuki ; Uchitomi, Yosuke

Purpose : The aim of this study was to identify the effects of a communication skills training (CST) program for oncologists, developed based on patient preferences regarding oncologists’ communication. Participants and Methods : Thirty oncologists were randomly assigned to either an intervention group (IG; 2-day CST workshop) or control group (CG). Participants were assessed on their communication performance during simulated consultation and their confidence in communicating with patients at [...]

A partir d'une revue systématique de la littérature publiée de 1980 à 2013 (27 études), cette étude fait le point sur les recommandations, normes et rapports de consensus existants dans le domaine des soins pédiatriques en psycho-oncologie

Pediatric psycho-oncology care: standards, guidelines, and consensus reports

Wiener, Lori ; Viola, Adrienne ; Koretski, Julia ; Perper, Emily Diana ; Patenaude, Andrea Farkas

Objective : The aim of this study was to identify existing guidelines, standards, or consensus-based reports for psychosocial care of children with cancer and their families. Purpose : Psychosocial standards of care for children with cancer can systematize the approach to care and create a replicable model that can be utilized in pediatric hospitals around the world. Determining gaps in existing standards in pediatric psycho-oncology can guide development of useful evidence-based and [...]