A partir d'une revue systématique de la littérature publiée entre 1979 et 2011, cette étude fait le point sur les besoins en soins de support de survivants d'un cancer hématologique

Supportive care needs of hematological cancer survivors: A critical review of the literature

Hall, Alix ; Lynagh, Marita ; Bryant, Jamie ; Sanson-Fisher, Rob

The purpose of this review was to determine the perceived supportive care needs of hematological cancer survivors, and the patient characteristics associated with higher levels of need. Medline, PsychInfo, CINAHL, EMBASE and PsycEXTRA, were searched for eligible articles published between 1979 and 2011. Ten full-text articles were identified. Extensive variation among study populations, methodologies and needs assessment measures used, made it difficult to synthesize results. Consequently, we [...]

Menée auprès de 138 patients atteints d'un cancer de la prostate, du sein ou d'autres tumeurs solides, cette étude analyse l'efficacité d'un programme d'exercices physiques comportant de la marche pour réduire la fatigue et la détresse émotionnelle des patients et améliorer la qualité du sommeil durant leur traitement

Impact of a Home-Based Walking Intervention on Outcomes of Sleep Quality, Emotional Distress, and Fatigue in Patients Undergoing Treatment for Solid Tumors

Wenzel, Jennifer A. ; Griffith, Kathleen A. ; Shang, JingJing ; Thompson, Carol B. ; Hedlin, Haley ; Stewart, Kerry J. ; DeWeese, Theodore ; Mock, Victoria

Purpose. Exercise use among patients with cancer has been shown to have many benefits and few notable risks. The purpose of this study was to evaluate the impact of a home-based walking intervention during cancer treatment on sleep quality, emotional distress, and fatigue.Methods. A total of 138 patients with prostate (55.6%), breast (32.5%), and other solid tumors (11.9%) were randomized to a home-based walking intervention or usual care. Exercise dose was assessed using a five-item subscale [...]

Menée auprès de 85 survivants adultes d'une leucémie lymphoblastique aiguë pédiatrique, cette étude transversale évalue leurs déficiences neurocognitives en fonction de la dose d'irradiation reçue lors d'une radiothérapie crânienne

Evaluation of Memory Impairment in Aging Adult Survivors of Childhood Acute Lymphoblastic Leukemia Treated With Cranial Radiotherapy

Armstrong, Gregory T. ; Reddick, Wilburn E. ; Petersen, Ronald C. ; Santucci, Aimee ; Zhang, Nan ; Srivastava, Deokumar ; Ogg, Robert J. ; Hillenbrand, Claudia M. ; Sabin, Noah ; Krasin, Matthew J. ; Kun, Larry ; Pui, Ching-Hon ; Hudson, Melissa M. ; Robison, Leslie L. ; Krull, Kevin R.

Background : Cranial radiotherapy (CRT) is a known risk factor for neurocognitive impairment in survivors of childhood cancer and may increase risk for mild cognitive impairment and dementia in adulthood. Methods : We performed a cross-sectional evaluation of survivors of childhood acute lymphoblastic leukemia (ALL) treated with 18 Gy (n = 127) or 24 Gy (n = 138) CRT. Impairment (age-adjusted score >1 standard deviation below expected mean, two-sided exact binomial test) on the Wechsler Memory [...]

Mené en Australie, cet essai randomisé évalue l'efficacité d'une psychothérapie de groupe pour aider les patients atteints d'un cancer localisé de la prostate à adapter leur vie psychologique et sexuelle face aux effets indésirables d'une prostatectomie

A randomised, wait-list controlled trial: evaluation of a cognitive–behavioural group intervention on psycho-sexual adjustment for men with localised prostate cancer

Siddons, Heather M. ; Wootten, Addie C. ; Costello, Anthony J.

Objective : To examine the effectiveness of a cognitive–behavioural therapy (CBT) group intervention to facilitate improved psycho-sexual adjustment to treatment side effects in prostate cancer survivors post-radical prostatectomy. Methods : A randomised, wait-list controlled trial was conducted with a total of 60 men who participated in a manualised 8-week cognitive–behavioural group intervention 6 months to 5 years post-radical prostatectomy for localised prostate cancer. Participants [...]

Menée au Danemark dans des centres de chirurgie (durée de suivi : 6 ans), cette étude analyse la prévalence, la sévérité et la persistance des douleurs et des troubles sensoriels chez des patientes ayant été traitées pour un cancer du sein

Persistent pain and sensory disturbances after treatment for breast cancer: six year nationwide follow-up study

Mathias Kvist Mejdahl ; Kenneth Geving Andersen ; Rune Gärtner ; Niels Kroman ; Henrik Kehlet

Objective : To examine the development of persistent pain after treatment for breast cancer and to examine risk factors associated with continuing pain. Design : Repeated cross sectional study in a previously examined nationwide cohort. All eligible women who underwent surgery for primary breast cancer in Denmark in 2005 and 2006 and were examined in 2008 were surveyed again with the same questionnaire. Setting : Surgical centres in Denmark. Main outcome measures Prevalence, location, and [...]

Menée auprès d'une cohorte multi-ethnique incluant 631 femmes âgées de 18 à 64 ans, cette étude américaine analyse l'évolution dans le temps de la pratique d'une activité physique chez des survivantes d'un cancer du sein

Long-term physical activity trends in breast cancer survivors

Mason, Caitlin ; Alfano, Catherine M. ; Smith, Ashley Wilder ; Wang, Ching-Yun ; Neuhouser, Marian L. ; Duggan, Catherine ; Bernstein, Leslie ; Baumgartner, Kathy B. ; Baumgartner, Richard N. ; Ballard-Barbash, Rachel ; McTiernan, Anne

Background:Physical activity is associated with reduced mortality and higher quality of life in breast cancer survivors; however, limited data on the prevalence of activity and long-term trends after diagnosis are available. Methods:A multi-ethnic cohort of 631 women (18-64 years) with stage 0-IIIA breast cancer were followed for 10 years. Recreational aerobic activity (MET-hrs/week) was ascertained for the year before diagnosis (baseline), 24 months, 5 and 10 years after enrollment. Women were [...]

Menée à partir du questionnaire européen EORTC QLQ adressé à 384 participantes, cette étude évalue les besoins en soins de support de patientes atteintes d'un cancer du sein, leur qualité de vie, et leur satisfaction vis-à-vis des soins reçus

Assessment of needs, health-related quality of life, and satisfaction with care in breast cancer patients to better target supportive care

Brédart, A. ; Kop, J.-L. ; Griesser, A.-C. ; Fiszer, C. ; Zaman, K. ; Panes-Ruedin, B. ; Jeanneret, W. ; Delaloye, J.-F. ; Zimmers, S. ; Berthet, V. ; Dolbeault, S.

Background : This study assessed whether breast cancer (BC) patients express similar levels of needs for equivalent severity of symptoms, functioning difficulties, or degrees of satisfaction with care aspects. BC patients who did (or not) report needs in spite of similar difficulties were identified among their sociodemographic or clinical characteristics. Patients and methods : Three hundred and eighty-four (73% response rate) BC patients recruited in ambulatory or surgery hospital services [...]

A partir de données de diverses sources, dont le registre national des décès, cette étude met à jour les données de mortalité par cancer du foie aux Etats-Unis, sur la période 1979-2008

Underestimation of Liver-Related Mortality in the United States

Asrani, Sumeet K. ; Larson, Joseph J. ; Yawn, Barbara ; Therneau, Terry M. ; Kim, W. Ray

According to the National Center for Health Statistics (NCHS), “chronic liver disease and cirrhosis” is the 12 th -leading cause of death in the United States (US). However, this single descriptor might not adequately enumerate all deaths from liver disease. The aim of our study was to update data on liver mortality in the US. Mortality data were obtained from the Rochester Epidemiology Project (REP; 1999–2008) and the National Death Registry (1979–2008). Liver-specific mortality values were [...]

Menée en Australie auprès d'une cohorte de 2 294 ouvriers travaillant en surface ou en profondeur dans des mines d'or, cette étude analyse l'incidence des cancers ainsi que la mortalité

Cancer incidence and mortality among underground and surface goldminers in Western Australia

Peters, S. ; Reid, A. ; Fritschi, L. ; Musk, A. W. ; de Klerk, N.

Background: In a cohort of goldminers, we estimated cancer mortality and incidence, for both surface and underground workers, and we examined the hypothesis that (underground) mining may be protective against prostate cancer. Methods: Standardised mortality and incidence ratios (SMRs and SIRs) and 95% confidence intervals (CI) were calculated to compare cancer mortality and incidence of former goldminers with that of the general male population. Internal comparisons on duration of underground [...]

Menée principalement auprès de patients d'origine afro-américaine, cette étude de cohorte urbaine analyse la mortalité par cancer chez une population infectée par le VIH

High cancer-related mortality in an urban, predominantly African–American, HIV-infected population

Riedel, David J. ; Mwangi, Evelyn Ivy W. ; Fantry, Lori E. ; Alexander, Carla ; Hossain, Mian B. ; Pauza, C. David ; Redfield, Robert R. ; Gilliam, Bruce L.

Objective: To determine mortality associated with a new cancer diagnosis in an urban, predominantly African–American, HIV-infected population. Design: Retrospective cohort study. Methods: All HIV-infected patients diagnosed with cancer between 1 January 2000 and 30 June 2010 were reviewed. Mortality was examined using Kaplan–Meier estimates and Cox proportional hazards models. Results: There were 470 cases of cancer among 447 patients. Patients were predominantly African–American (85%) and male [...]

A partir des données d'une enquête nationale menée de 1997 à 2004, cette étude américaine analyse et compare, chez des fumeurs et chez des anciens fumeurs en surcharge pondérale ou obèses, le risque de mortalité par cancer

It is better to be a fat ex-smoker than a thin smoker: findings from the 1997–2004 National Health Interview Survey−National Death Index linkage study

Siahpush, Mohammad ; Singh, Gopal K ; Tibbits, Melissa ; Pinard, Courtney A ; Shaikh, Raees A ; Yaroch, Amy

Objective The aim of this research was to compare the risk of all-cause mortality and mortality from all cancers combined, lung cancer, respiratory diseases, cardiovascular diseases and diabetes mellitus between normal-weight smokers and overweight or obese ex-smokers. Methods Data were from 1997 to 2004 National Health Interview Survey (with response rates ranging from 70% to 80%) which were linked to records in the National Death Index. Mortality follow-up was through 31 December 2006. The [...]

Menée auprès de 130 cas et de130 témoins adultes non malades, cette étude analyse les volumes des diverses zones du cerveau chez des survivants à long terme d'une leucémie lymphoblastique aiguë survenue pendant l'enfance

Reduced Neuroanatomic Volumes in Long-Term Survivors of Childhood Acute Lymphoblastic Leukemia

Zeller, Bernward ; Tamnes, Christian K. ; Kanellopoulos, Adriani ; Amlien, Inge K. ; Andersson, Stein ; Due-Tønnessen, Paulina ; Fjell, Anders M. ; Walhovd, Kristine B. ; Westlye, Lars T. ; Ruud, Ellen

Purpose To compare regional brain volumes in adult long-term survivors of childhood acute lymphoblastic leukemia (ALL) and healthy controls. Patients and Methods We investigated 130 survivors of childhood ALL diagnosed between 1970 and 2002 with magnetic resonance imaging (MRI) and neuropsychological testing at a median of 22.5 years after diagnosis. Morphometric analyses including whole-brain segmentation were performed using a validated automated procedure; 130 healthy adults served as [...]

Menée au Royaume-Uni auprès de 1 432 participants, cette étude évalue l'association entre un faible statut socioéconomique, les caractéristiques du patient lors du diagnostic d'un cancer du poumon, le stade de la tumeur au diagnostic, ainsi que la survie

Social deprivation does not affect lung cancer stage at presentation or disease outcome

Cheyne, L. ; Taylor, A. ; Milton, R. ; Fear, J. ; Callister, M. E. J.

Abstract : Introduction Lung cancer mortality rates are higher in more deprived populations. This may simply reflect higher incidence of the disease, or additionally delayed presentation and worse outcomes amongst more deprived patients. Low socio-economic status (SES) has also been linked to cancer fatalism which might account for such differences. We determined the interaction between SES, patient's characteristics at presentation with lung cancer, and disease outcome at a large UK teaching [...]

A partir de données 2004-2007 des registres américains des cancers et celles de la base d'assurance maladie Medicare, cette étude analyse l'utilisation de la chirurgie, de la chimiothérapie ou de la radiothérapie chez 2 958 patients âgés atteints d'un cancer du poumon non à petites cellules de stade IIIA

Variability in the Treatment of Elderly Patients with Stage IIIA (N2) Non-Small-Cell Lung Cancer

Berry, Mark F. ; Worni, Mathias ; Pietrobon, Ricardo ; D’Amico, Thomas A. ; Akushevich, Igor

Introduction: We evaluated treatment patterns of elderly patients with stage IIIA (N2) non-small-cell lung cancer (NSCLC). Methods: The use of surgery, chemotherapy, and radiation for patients with stage IIIA (T1-T3N2M0) NSCLC in the Surveillance, Epidemiology, and End Results-Medicare database from 2004 to 2007 was analyzed. Treatment variability was assessed using a multivariable logistic regression model that included treatment, patient, tumor, and census track variables. Overall survival [...]

Menée aux Etats-Unis sur la période 1989-2009 auprès de 75 cas et de 150 témoins, cette étude analyse et compare la survie des patientes atteintes d'un cancer du sein, enceintes ou non, et traitées par chimiothérapie

Case Control Study of Women Treated With Chemotherapy for Breast Cancer During Pregnancy as Compared With Nonpregnant Patients With Breast Cancer

Litton, Jennifer K. ; Warneke, Carla L. ; Hahn, Karin M. ; Palla, Shana L. ; Kuerer, Henry M. ; Perkins, George H. ; Mittendorf, Elizabeth A. ; Barnett, Chad ; Gonzalez-Angulo, Ana M. ; Hortobagyi, Gabriel N. ; Theriault, Richard L.

Background. The purpose of this analysis was to compare disease-free survival (DFS), progression-free survival (PFS), and overall survival (OS) between pregnant and nonpregnant patients with breast cancer. Methods. From 1989 to 2009, 75 women were treated with chemotherapy during pregnancy. Each pregnant case was matched on age and cancer stage to two nonpregnant patients with breast cancer (controls). Fisher’s exact test, the Kaplan-Meier method, and Cox proportional hazards regression models [...]

A partir des données des registres américains des cancers portant sur la période 1992-2009, cette étude analyse l'évolution de l'incidence du cancer de l'endomètre chez les femmes ménopausées

Recent changes in endometrial cancer trends among menopausal-age US women

Wartko, Paige ; Sherman, Mark E. ; Yang, Hannah P. ; Felix, Ashley S. ; Brinton, Louise A. ; Trabert, Britton

Abstract : Background Changes in endometrial cancer incidence rates after the precipitous decline in menopausal hormone therapy (MHT) use in 2002 have not been evaluated. Methods : Using data from the Surveillance, Epidemiology, and End Results Program from 1992 to 2009 (SEER 13), we identified 63 428 incident endometrial cancer cases among women ages 20–74. We compared annual percent change (APC) in endometrial cancer incidence rates from 1992 to 2002 to rates from 2003 to 2009. Results : In [...]

A partir de données d'hospitalisation, cette étude analyse l'évolution de l'incidence du carcinome in situ de la vessie en Australie depuis 2001

Bladder carcinoma in situ (CIS) in Australia: a rising incidence for an under-reported malignancy

Ranasinghe, Weranja K. B. ; Attia, John ; Oldmeadow, Christopher ; Lawrentschuk, Nathan ; Robertson, Jane ; Ranasinghe, Tamra ; Bolton, Damien ; Persad, Raj

Objectives * To investigate the incidence of carcinoma in situ (CIS) in Australia and examine implications for its diagnosis and management, as CIS of the urinary bladder is a non-reportable disease in Australia. Methods * Analysis of annual hospitalisation data using Australian Institute of Health and Welfare (AIHW) datasets showed an increase in CIS from 2001 onwards. * To determine whether the increase seen with AIHW data represented a true increase in the rates offices, patient level data [...]

Menée au Canada sur la période 1986-2001 en population masculine, cette étude observationnelle évalue l'évolution des disparités sociales dans la mortalité par cancer des voies supérieures aéro-digestives associé au tabagisme

An observational study to assess changes in social inequality in smoking-attributable upper aero digestive tract cancer mortality among Canadian males between 1986 and 2001

Singhal, Sonica ; Quinonez, Carlos ; Jha, Prabhat

BACKGROUND:Tobacco and low socioeconomic status have been acknowledged as potential risk factors for upper aero-digestive tract (UADT) cancers in North America. In context of reducing adult male smoking prevalence (by over 50%), in the past few decades in Canada, this study tried to document changes in smoking-attributable UADT cancer mortality rates, among Canadian males of different social strata, between 1986 and 2001. METHODS:The contribution of smoking to UADT cancer mortality was [...]

A partir des données de trois registres des cancers portant sur 277 immigrants de première génération survivants d'un cancer et 319 survivants anglo-australiens, cette étude australienne analyse et compare leur qualité de vie et leur bien-être psychosocial

Inferior health-related quality of life and psychological well-being in immigrant cancer survivors: A population-based study

Butow, Phyllis N. ; Aldridge, Lynley ; Bell, Melanie L. ; Sze, Ming ; Eisenbruch, Maurice ; Jefford, Michael ; Schofield, Penelope ; Girgis, Afaf ; King, Madeleine ; Duggal-Beri, Priya ; McGrane, Joshua ; Goldstein, David

This study compared health-related quality of life (QOL) and psychological morbidity in a population-based sample of first generation immigrant and Anglo-Australian cancer survivors. Eligible participants, recruited via three State Cancer Registries, included those: with a new diagnosis of one of 12 most incident cancers (all stages) 1–6 years earlier; aged 18–80 at diagnosis; born in a Chinese, Arabic, or Greek speaking country and able to speak one of these languages. A random sample of [...]

Menée par enquête auprès de 315 femmes atteintes d'un carcinome canalaire in situ, cette étude de cohorte américaine analyse leurs perceptions relatives au risque à long terme d'un cancer invasif du sein

Long-Term Risk Perceptions of Women With Ductal Carcinoma In Situ

Ruddy, Kathryn J. ; Meyer, Meghan E. ; Giobbie-Hurder, Anita ; Emmons, Karen M. ; Weeks, Jane C. ; Winer, Eric P. ; Partridge, Ann H.

Introduction. Previous research has demonstrated that many women with ductal carcinoma in situ (DCIS) overestimate their risk for future breast cancer at the time of diagnosis and soon thereafter. This study aims to evaluate risk perceptions after 5 years. Patients and Methods. In a longitudinal cohort study, we mailed long-term follow-up surveys to 315 women who had previously responded to a survey 18 months after they were diagnosed with DCIS, excluding those who had experienced recurrence [...]

Cette étude américaine évalue l'efficacité des infirmières coordinatrices de parcours de soins pour raccourcir les délais d'attente entre le diagnostic de cancer du sein et les traitements reçus dans un centre de lutte contre le cancer

The effect of nurse navigation on timeliness of breast cancer care at an academic comprehensive cancer center

Basu, Mohua ; Linebarger, Jared ; Gabram, Sheryl G. A. ; Patterson, Sharla Gayle ; Amin, Miral ; Ward, Kevin C.

BACKGROUND A patient navigation process is required for accreditation by the National Accreditation Program for Breast Centers (NAPBC). Patient navigation has previously been shown to improve timely diagnosis in patients with breast cancer. This study sought to assess the effect of nurse navigation on timeliness of care following the diagnosis of breast cancer by comparing patients who were treated in a comprehensive cancer center with and without the assistance of nurse navigation. METHODS [...]

Menée dans un centre américain de lutte contre le cancer, cette étude décrit l'implémentation du programme "Death with Dignity" pour les patients atteints de cancer en phase terminale entre mars 2009 et décembre 2011

Implementing a Death with Dignity Program at a Comprehensive Cancer Center

Loggers, Elizabeth Trice ; Starks, Helene ; Shannon-Dudley, Moreen ; Back, Anthony L. ; Appelbaum, Frederick R. ; Stewart, F. Marc

Background : The majority of Death with Dignity participants in Washington State and Oregon have received a diagnosis of terminal cancer. As more states consider legislation regarding physician-assisted death, the experience of a comprehensive cancer center may be informative. Methods : We describe the implementation of a Death with Dignity program at Seattle Cancer Care Alliance, the site of care for the Fred Hutchinson–University of Washington Cancer Consortium, a comprehensive cancer center [...]