Menée à l'aide d'une modélisation et de données d'une cohorte de 182 011 personnes (durée moyenne de suivi : 19,3 ans), cette étude analyse l'association entre le nombre de paquets-années, le nombre d'années d'arrêt et le risque de cancer du pancréas (1 831 cas), en fonction de l'origine ethnique

Excess pancreatic cancer risk due to smoking and modifying effect of quitting smoking: The Multiethnic Cohort Study

Bogumil, David ; Stram, Daniel ; Preston, Dale L. ; Pandol, Stephen J. ; Wu, Anna H. ; McKean-Cowdin, Roberta ; Conti, David V. ; Setiawan, Veronica Wendy

Purpose: Risk factors for pancreatic cancer include racial/ethnic disparities and smoking. However, risk trajectories by smoking history and race/ethnicity are unknown. We examined the association of smoking with pancreatic cancer by race/ethnicity to generate age-specific incidence estimates by smoking history. Methods: We modeled pancreatic cancer incidence by race/ethnicity, age, pack-years, and years-quit using an excess relative risk model for 182,011 Multiethnic Cohort participants. We [...]

Menée en Chine sur la période 1950-1980 auprès de 25 782 témoins et 27 011 professionnels de radiologie médicale, cette étude analyse l'association entre une exposition à de faibles doses de rayonnements et le risque de cancer par localisation (1 643 cas)

Association of low-dose ionising radiation with site-specific solid cancers: Chinese medical X-ray workers cohort study, 1950–1995

Yeqing Gu ; Jinhan Wang ; Yan Wang ; Chang Xu ; Yang Liu ; Liqing Du ; Qin Wang ; Kaihua Ji ; Ningning He ; Manman Zhang ; Huijuan Song ; Kaijun Niu ; Qiang Liu

Background: The dose–response relationship between cancers and protracted low-dose rate exposure to ionising radiation is still uncertain. This study aims to estimate quantified relationships between low-dose radiation exposures and site-specific solid cancers among Chinese medical X-ray workers. Methods: This cohort study included 27 011 individuals who were employed at major hospitals in 24 provinces in China from 1950 to 1980 and had been exposed to X-ray equipment, and a control group of [...]

Menée à partir de données 2011-2020 d'une enquête réalisée auprès de 5 715 personnes, cette étude analyse l'association entre une exposition aux trihalométhanes et le risque de carcinome cutané non-mélanome

Bromoform exposure is associated with non-melanoma skin cancer: evidence from NHANES 2011-2020

Gao, M. ; Guo, H. ; Han, J. ; Liu, J. ; Hou, Y. ; Wang, Z. ; Yang, Z. ; Wang, Q.

BACKGROUND: Non-melanoma skin cancer (NMSC) is a prevalent skin malignancy. It has been indicated in many studies that trihalomethanes (THMs) exposure has a strong association with tumors but has not been associated with NMSC. Our investigation aims to explore the association between THMs exposure and NMSC. METHODS: Cross-sectional data from the 2011 to 2020 National Health and Nutrition Examination Survey (NHANES) was collected. Poisson regression and subgroup analyses were performed to [...]

Menée à partir de données 2012-2019 de la "California Teachers Study" portant sur 38 470 témoins et 1 085 patientes atteintes d'un cancer du sein, cette étude analyse l'association entre des caractéristiques du sommeil (qualité, latence, durée, utilisation de somnifères, chronotype) et le risque de développer la maladie

Prospective analysis of sleep characteristics, chronotype, and risk of breast cancer in the california teachers study

Von Behren, Julie ; Goldberg, Debbie ; Hurley, Susan ; Clague DeHart, Jessica ; Wang, Sophia S. ; Reynolds, Peggy

Purpose: Poor sleep quality and evening chronotype were associated with increased risk of breast cancer in a previous retrospective study in the California Teachers Study (CTS). The present analysis examines these sleep factors prospectively in the same cohort of women. Methods: From the CTS, we included 1,085 incident breast cancer cases and 38,470 cancer-free participants from 2012 through 2019. We calculated time at risk and used Cox proportional hazards regression models to estimate the [...]