Cette étude passe en revue les études concernant le soutien nutritionnel des patients âgés atteints d'un cancer de l'oesophage traité par chiomioradiothérapie

Nutritional Support in Older Patients with Esophageal Cancer Undergoing Chemoradiotherapy

Doğan Akagündüz, Diğdem ; Türker, Perim Fatma

Esophageal cancer (EC) is the eighth most prevalent malignancy and the sixth leading cause of cancer-related death worldwide. The proportion of older adults with EC has increased dramatically in recent decades due to increased life expectancy. Older patients with EC are at a highest risk of malnutrition and this predicts early death. In older patients with EC, dysphagia is a common symptom; additionally, comorbidities, polypharmacy, and physiological changes of aging such as decreased muscle [...]

Menée à partir des données 1973-2016 des registres américains des cancers portant sur les patients de plus de 65 ans, cette étude analyse l'effet des tendances de l'incidence, de la survie relative et du stade au moment du diagnostic sur la prévalence des cancers (poumon, prostate, côlon, sein, vessie, ovaires, estomac, pancréas, oesophage, rein, foie et mélanome cutané)

Underlying mechanisms of change in cancer prevalence in older U.S. adults: contributions of incidence, survival, and ascertainment at early stages

Akushevich, I. ; Yashkin, A. ; Kovtun, M. ; Yashin, A. I. ; Kravchenko, J.

Purpose: To quantitatively evaluate contributions of trends in incidence, relative survival, and stage at diagnosis to the dynamics in the prevalence of major cancers (lung, prostate, colon, breast, urinary bladder, ovaries, stomach, pancreas, esophagus, kidney, liver, and skin melanoma) among older U.S. adults age 65 +. Methods: Trend partitioning was applied to the Surveillance, Epidemiology, and End Results Program data for 1973–2016. Results: Growth of cancer prevalence in older adults [...]

Menée à partir de données portant sur plus de 2,5 millions d'enfants nés au Danemark sur la période 1978-2018, cette étude analyse l'effet, sur la santé pendant l'enfance et la mortalité, d'une exposition in utero à un diagnostic maternel de cancer et/ou à une chimiothérapie

Long-Term Morbidity and Mortality in Children After In Utero Exposure to Maternal Cancer

Iben K. Greiber ; Jakob H. Viuff ; Lone Storgaard ; Mona A. Karlsen ; Øjvind Lidegaard ; Anders P. Mikkelsen ; Lene Mellemkjær ; Cristel S. Hjortshøj

PURPOSE: In utero exposure to maternal cancer and cancer treatment might influence the child's short- and long-term health and development. The objective of the study was to investigate short- and long-term somatic and psychiatric outcomes in children exposed to maternal cancer in utero. METHODS: This nationwide cohort study identified all liveborn children in Denmark between January 1978 and December 2018. Exposure was defined as maternal cancer diagnosis during pregnancy, and in a subgroup [...]

Menée aux Etats-Unis à l'aide des données 2008-2013 d'une enquête, cette étude analyse les disparités, en milieu rural, dans les facteurs de risque de cancer et les comportements de dépistage

Cancer disparities in the context of rurality: risk factors and screening across various U.S. rural classification codes

Hirko, Kelly A. ; Xu, Huiwen ; Rogers, Laura Q. ; Martin, Michelle Y. ; Roy, Siddhartha ; Kelly, Kimberly M. ; Christy, Shannon M. ; Ashing, Kimlin Tam ; Yi, Jean C. ; Lewis-Thames, Marquita W. ; Meade, Cathy D. ; Lu, Qian ; Gwede, Clement K. ; Nemeth, Julianna ; Ceballos, Rachel M. ; Menon, Usha ; Cueva, Katie ; Yeary, Karen ; Klesges, Lisa M. ; Baskin, Monica L. ; Alcaraz, Kassandra I. ; Ford, Sabrina

Purpose: Prior cancer research is limited by inconsistencies in defining rurality. The purpose of this study was to describe the prevalence of cancer risk factors and cancer screening behaviors across various county-based rural classification codes, including measures reflecting a continuum, to inform our understanding of cancer disparities according to the extent of rurality. Methods: Using an ecological cross-sectional design, we examined differences in cancer risk factors and cancer [...]

Menée auprès de 4 372 patients adultes atteints d'un cancer, cette étude analyse la prévalence des idées suicidaires et identifie les facteurs de risque psychosociaux, sociodémographiques ou liés à la maladie

Suicidal ideation in patients with cancer: Its prevalence and results of structural equation modelling

Sauer, Christina ; Grapp, Miriam ; Bugaj, Till J. ; Maatouk, Imad

Objective: Patients with cancer have a higher risk of suicidal ideation (SI) and suicidality than the general population. This study was designed to investigate the prevalence of SI and its association with psychosocial and sociodemographic factors and tumour entity. Methods: In this observational cross-sectional study, 4372 adult patients with different cancer entities were enrolled. We assessed the outcome variables (i.e. SI, depressive and anxiety symptoms, mental and physical fatigue and [...]

Menée à l'aide de données des registres américains des cancers portant sur les enfants et les adolescents ayant reçu un diagnostic de cancer entre 2007 et 2016, cette étude analyse les disparités ethniques dans le stade au diagnostic, en fonction de leur couverture maladie

The impact of health insurance coverage on racial/ethnic disparities in US childhood and adolescent cancer stage at diagnosis

Wang, Xiaoyan ; Brown, Derek S. ; Cao, Yin ; Ekenga, Christine C. ; Guo, Shenyang ; Johnson, Kimberly J.

Background: Racial/ethnic minority children and adolescents are more likely to have an advanced cancer diagnosis compared with non-Hispanic Whites, which may relate to the lack of consistent health care access. This study aims to describe racial/ethnic disparities in cancer diagnosis stage among children and adolescents and assess whether health insurance mediates these disparities. Methods: Data on individuals ≤19 years of age diagnosed with primary cancers from 2007 to 2016 were obtained from [...]

Menée en Australie à l'aide de données 2017-2018 du registre des cancers portant sur 171 patientes atteintes d'un cancer primitif de l'ovaire, cette étude analyse les différences dans leur prise en charge (diagnostic et traitement)

Variation in ovarian cancer care in Australia: An analysis of patterns of care in diagnosis and initial treatment in New South Wales

White, Kahren M. ; Walton, Richard J. ; Kwedza, Ru K. ; Rushton, Shelley ; Currow, David C. ; Seale, Holly ; Harrison, Reema

Objective: Ovarian cancer has the highest mortality of all gynaecological cancers. This study aimed to identify the extent to which women across New South Wales experienced variation in their care in diagnosis and initial treatment for ovarian cancer against the national optimal care pathway for ovarian cancer. Method: Clinical audit methodology was utilised to explore variations for women with primary ovarian cancer; 171 eligible cases were identified through by the NSW Cancer Registry for the [...]

Menée à l'aide de données 2017-2019 portant sur 143 patients atteints d'un cancer du poumon non à petites cellules de stade métastatique (âge médian : 63 ans ; 37,8 % de femmes), cette étude analyse l'association entre la charge allostatique (conséquences de l'adaptation biologique au stress), les déterminants sociaux de la santé et la mortalité globale

Association of Allostatic Load With Overall Mortality Among Patients With Metastatic Non–Small Cell Lung Cancer

Obeng-Gyasi, Samilia ; Li, Yaming ; Carson, William E. ; Reisenger, Sarah ; Presley, Carolyn J. ; Shields, Peter G. ; Carbone, David P. ; Ceppa, DuyKhanh P. ; Carlos, Ruth C. ; Andersen, Barbara L.

Adverse social determinants of health (SDHs) (eg, poverty) are associated with poor oncologic outcomes among patients with lung cancer. However, no studies have evaluated biological correlates of adverse SDHs, operationalized as allostatic load (AL), with mortality due to lung cancer.To examine the association among AL, SDHs, and mortality among patients with metastatic non–small cell lung cancer (NSCLC).This cross-sectional study of an observational cohort was performed at a National Cancer [...]

Menée à partir de données 2004-2018 des registres américains des cancers portant sur 109 660 patients atteints d'un méningiome, cette étude analyse les tendances dans l'incidence et la survie puis identifie des facteurs pronostiques

Incidence and Survival of Benign, Borderline, and Malignant Meningioma Patients in the United States from 2004 to 2018

Cao, Junguo ; Yan, Weijia ; Li, Guihong ; Zhan, Zhixin ; Hong, Xinyu ; Yan, Hong

Meningioma is the most common primary central nervous system tumor, and its incidence is increasing. A systematic epidemiological and clinical analysis is required to better estimate its public health impact and understand its prognostic factors. Data were obtained from the Surveillance, Epidemiology, and End Results (SEER) database from 2004 to 2018 for all types of meningiomas without an age restriction. Age-adjusted incidence rates (IRs) and 95% confidence intervals were estimated according [...]

Menée à l'aide de données 2013-2016 des registres nationaux du cancer en France et à Taïwan portant sur 9 398 patients, cette étude compare, en fonction du type histologique, les données d'incidence des sarcomes des tissus mous et identifie les caractéristiques cliniques divergentes

Soft tissue sarcoma incidences and clinical characteristics are significantly different in France and Taiwan

Chen, Tom Wei-Wu ; Chiang, Ruru Chun-Ju ; Le Cesne, Alex ; Hsieh, Yu-Chun ; Italiano, Antoine ; Yang, Ya-Wen ; Penel, Nicolas ; Lee, Wen-Chung ; Bompas, Emmanuelle ; Valentin, Thibaud ; Anract, Philippe ; Firmin, Nelly ; Duffaud, Florence ; Cheng, Ann-Lii ; Ducimetiere, Francoise ; Chan, K. Arnold ; Blay, Jean-Yves

Background: The incidence of different soft tissue sarcoma (STS) histotypes among ethnic and geographic populations has not been comprehensively investigated. Methods: Data from 2013 to 2016 were obtained from national cancer registry databases in France and Taiwan. Liposarcoma (LPS), leiomyosarcoma (LMS), angiosarcoma (AS), synovial sarcoma (SS), and malignant peripheral nerve sheath tumor (MPNST) were selected as index STSs to estimate the age-standardized incidence rates (ASRs) and other [...]

Menée au Royaume-Uni par enquête et/ou entretien auprès de 144 patients ayant survécu à un cancer de la tête et du cou et auprès de leur famille, cette étude analyse l'acceptabilité et la faisabilité de l'éducation thérapeutique du patient pour son suivi

Exploring the views of patients' and their family about patient-initiated follow-up in head and neck cancer: A mixed methods study

Lorenc, Ava ; Greaves, Colin ; Duda, Joan ; Brett, Jo ; Matheson, Lauren ; Fulton-Lieuw, Tessa ; Secher, Denis ; Rhodes, Pat ; Ozakinci, Gozde ; Nankivell, Paul ; Mehanna, Hisham ; Jepson, Marcus ; PETNECK2 Research Team

Objective: The objective of this work was to explore head and neck cancer (HNC) patients' and their family members' views on acceptability and feasibility of patient-initiated follow-up (PIFU), including concerns and anticipated benefits. Methods: Patients were recruited from UK HNC clinics, support groups and advocacy groups. They completed a survey (n = 144) and/or qualitative interview (n = 30), three with a family member. Qualitative data were analysed thematically, quantitative data using [...]