A partir d'une revue systématique de la littérature (17 études, 287 576 personnes), cette méta-analyse évalue l'association entre l'utilisation d'un traitement endocrinien adjuvant et le risque de cancer controlatéral chez des patientes ayant survécu à un cancer du sein

Adjuvant endocrine therapy and risk of contralateral breast cancer: a systematic review and meta-analysis of observational studies

Ghosh, Rajrupa ; Pfeiffer, Ruth M. ; Roberts, Sylvia ; Gierach, Gretchen L. ; Dallal, Cher M.

Purpose: Randomized clinical trials support reductions in contralateral breast cancer (CBC) risk with use of adjuvant endocrine therapy, however, real-world treatment effects, particularly for subgroups of breast cancer survivors, remain inconclusive. To address this, population-based observational studies of adjuvant endocrine therapy and CBC were synthesized and meta-analyzed. Methods: PubMed and Embase databases were systematically searched for observational studies of endocrine therapy use [...]

Menée auprès de 378 jeunes utilisateurs de cigarettes électroniques (âge : 13-18 ans), cette étude analyse l'influence, sur leur intention d'arrêter de vapoter, de différentes caractéristiques de vidéos TikTok pour promouvoir le sevrage tabagique

Effects of Message Frames and Sources in TikTok Videos for Youth Vaping Cessation: Emotions and Perceived Message Effectiveness as Mediating Mechanisms

Wu, Jiaxi ; Fetterman, Jessica L. ; Cornacchione Ross, Jennifer ; Hong, Traci

Purpose: The objective of this study was to evaluate the effect of message frames (gain vs. loss) and sources (formal expert: a health-care professional vs. informal expert: an individual who successfully quit vaping) on the persuasiveness of TikTok videos among youth who currently use e-cigarettes. Additionally, the study examined how emotional responses and perceived message effectiveness (PME) mediate the framing effect on youth intention to quit vaping. Methods: A 2 (gain frame vs. loss [...]