A partir d'une revue systématique de la littérature publiée jusqu'en octobre 2022 (63 études), cette méta-analyse évalue l'association entre une exposition au tabagisme passif et le risque de cancer du sein chez des femmes non-fumeuses

Exposure to second-hand smoke and breast cancer risk in non-smoking women: a comprehensive systematic review and meta-analysis

Possenti, Irene ; Scala, Marco ; CARRERAS, Giulia ; Bagnardi, Vincenzo ; Bosetti, Cristina ; GORINI, Giuseppe ; Maci, Caterina ; Malevolti, Maria Chiara ; Odone, Anna ; Smits, Luc ; Specchia, Claudia ; GALLUS, Silvano ; Lugo, Alessandra

Through the use of an innovative method to identify original publications, we conducted a meta-analysis of all epidemiological studies evaluating the association between second-hand smoke (SHS) exposure and breast cancer risk among female non-smokers published in English up to October 2022. Pooled relative risks (RR) were obtained through the use of random-effects models. Dose–response relationships were derived using log-linear functions. Out of 73 identified eligible studies, 63 original [...]

Menée à l'aide d'une méthode de randomisation mendélienne et de données des bases "IEU OPEN GWAS" et "FinnGen", cette étude analyse l'association entre 15 facteurs nutritionnels et le risque de cancer colorectal

Dietary Factors and the Risk of Colorectal Cancer: A Mendelian Randomization Study

Li, Xingyuan ; Pan, Shengqi ; Wang, Jiaqi ; Chang, Zewen ; Xiong, Huan ; Ding, Ke ; Tang, Qingchao

To examine the causal association between 15 dietary factors and the incidence of colorectal cancer through the application of Mendelian randomization methodology. The data associated with 15 dietary factors were derived from the IEU OPEN GWAS database, and the colorectal cancer data were sourced from the FinnGen database. The Inverse Variance Weighting method was the principal research method. Sensitivity analyses were implemented to affirm the robustness of the findings. Additionally, we [...]

Menée auprès de 25 347 hommes inclus dans une cohorte d'employés de l'industrie pétrolière offshore sur la période 1965-1998 et menée à l'aide de données du registre norvégien des cancers, cette étude analyse l'association entre une exposition professionnelle à l'amiante ou aux fibres céramiques réfractaires et le risque de mésothéliome pleural

Exposure to fibres and risk of pleural mesothelioma in the Norwegian Offshore Petroleum Workers cohort

Berge, Leon Alexander Mclaren ; Shala, Nita Kaupang ; Barone-Adesi, Francesco ; Hosgood, H Dean ; Samuelsen, Sven Ove ; Bråtveit, Magne ; Kirkeleit, Jorunn ; Silverman, Debra ; Friesen, Melissa C ; Babigumira, Ronnie ; Grimsrud, Tom K ; Veierød, Marit B ; Stenehjem, Jo S

Objectives: Pleural mesothelioma is a rare respiratory cancer, mainly caused by inhalation of asbestos fibres. Other inorganic fibres are also suggested risk factors. We aimed to investigate the association between exposure to asbestos or refractory ceramic fibres (RCFs) and pleural mesothelioma among male Norwegian offshore petroleum workers. Methods: Among 25 347 men in the Norwegian Offshore Petroleum Workers (NOPW) cohort (1965–1998), 43 pleural mesothelioma cases were identified through [...]

A partir d'une revue systématique de la littérature publiée jusqu'en juillet 2022 (113 études), cette méta-analyse évalue le risque de cancer chez des personnes infectées par le VIH ou ayant bénéficié d'une greffe d'organe

Cancer risk in people living with HIV and solid organ transplant recipients: a systematic review and meta-analysis

Jin, Fengyi ; Vajdic, Claire M. ; Poynten, I. Mary ; McGee-Avila, Jennifer K. ; Castle, Philip E. ; Grulich, Andrew E.

Background: Systematic evaluations of cancer risk in people living with HIV or AIDS (PLHIV) and solid organ transplant recipients provide unique insights into the role of the immune system in cancer development. In this systematic review and meta-analysis, we expand previous analyses of cancer risk for these two immunocompromised populations. Methods: We considered studies published in English and listed on PubMed or Embase up to July 1, 2022. Studies were eligible for inclusion if they used [...]

Menée à l'aide de données suédoises portant sur 6 694 personnes atteintes de polydactylie, cette étude analyse leur risque de cancer en fonction du sexe

Cancer risk in individuals with polydactyly: a Swedish population-based cohort study

Wachtmeister, Alexandra ; Tettamanti, Giorgio ; Nordgren, Ida ; Norrby, Christina ; Laurell, Tobias ; Lu, Yunxia ; Skarin Nordenvall, Anna ; Nordgren, Ann

Background: Polydactyly is a feature of several cancer predisposition syndromes (CPS), however, cancer risk in individuals with polydactyly is largely unknown. Methods: We performed a matched cohort study using data from Swedish national registers. We included 6694 individuals with polydactyly, born in Sweden between 1970–2017. Polydactyly was categorised as thumb polydactyly, finger polydactyly, polydactyly+ (additional birth defects and/or intellectual disability) or isolated polydactyly. [...]

Menée à partir de données de registres suédois et danois portant sur 514 440 témoins et 12 868 patientes atteintes d'un cancer de l'ovaire, cette étude identifie des facteurs associés au risque de développer la maladie en fonction de l'existence d'antédécents familiaux de cancer du sein et/ou de l'ovaire

Ovarian cancer risk factors in relation to family history

Zheng, Guoqiao ; Baandrup, Louise ; Wang, Jiangrong ; Hertzum-Larsen, Rasmus ; Gerd Hannibal, Charlotte ; Tuxen Faber, Mette ; Sundström, Karin ; Kjær, Susanne K

Women with a family history of breast and/or ovarian cancer have an increased ovarian cancer risk. Yet it remains uncertain if common ovarian cancer risk factors—especially those which are modifiable—affect this high-risk population similarly to the general population.Using the Danish and Swedish nationwide registers, we established two nested case-control study populations in women with a family history of breast and/or ovarian cancer (2,138 ovarian cancers, 85,240 controls) and women without [...]

Menée au Nouveau-Mexique à l'aide de données de biopsies mammaires portant sur 10 271 femmes présentant une maladie bénigne du sein, cette étude analyse leur risque de cancer du sein en fonction de leur origine ethnique

Understanding Benign Breast Disease and Subsequent Breast Cancer in Hispanic White Females: A Step Closer to Evidence-Based Management

Lohani, Kush R. ; Nibbe, Andrea M. ; Vierkant, Robert A. ; Pacheco-Spann, Laura M. ; Seymour, Lisa R. ; Vachon, Celine M. ; Sherman, Mark E. ; Winham, Stacey J. ; Degnim, Amy C. ; Hill, Deirdre A.

Although Hispanic White (HW) females have a lower incidence of breast cancer than non-Hispanic White (NHW) females, breast cancer risk is unclear for HW females after benign breast disease (BBD).We compared BBD characteristics and subsequent breast cancer risk among HW and NHW females in New Mexico using a population-based collection of benign breast biopsies (1996–2007). BBD was categorized as nonproliferative disease (NPD), proliferative disease without atypia (PDWA), or atypical hyperplasia [...]