Nota Bene Cancer
Nota Bene Cancer est un bulletin hebdomadaire de veille bibliographique. En libre accès, Nota Bene Cancer permet à ses abonnés de gagner du temps pour se tenir informé de l’actualité scientifique et médicale dans les divers domaines de la recherche sur les cancers.
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Sommaire du n° 479 du 19 février 2021
Lutte contre les cancers
Qualité de vie, soins de support (6)
Menée en Australie auprès de 333 patients atteints d'un cancer, cette étude de cohorte identifie les facteurs associés au risque et à la persistance d'une neuropathie périphérique induite par une chimiothérapie à base de paclitaxel ou d'oxaliplatine
Hemoglobin, Body Mass Index, and Age as Risk Factors for Paclitaxel- and Oxaliplatin-Induced Peripheral Neuropathy
Menée en Australie auprès de 333 patients atteints d'un cancer, cette étude de cohorte identifie les facteurs associés au risque et à la persistance d'une neuropathie périphérique induite par une chimiothérapie à base de paclitaxel ou d'oxaliplatine
Hemoglobin, Body Mass Index, and Age as Risk Factors for Paclitaxel- and Oxaliplatin-Induced Peripheral Neuropathy
Mizrahi, David ; Park, Susanna B. ; Li, Tiffany ; Timmins, Hannah C. ; Trinh, Terry ; Au, Kimberley ; Battaglini, Eva ; Wyld, David ; Henderson, Robert D. ; Grimison, Peter ; Ke, Helen ; Geelan-Small, Peter ; Marker, Julie ; Wall, Brian ; Goldstein, David
Importance : Chemotherapy-induced peripheral neuropathy (CIPN) is a debilitating adverse effect of neurotoxic cancer treatments including taxanes and platinum agents. Limited knowledge exists of potential prechemotherapy factors associated with CIPN development. Objective : To identify the association of pretreatment blood-based and clinical factors with CIPN persistence in patients who received paclitaxel or oxaliplatin. Design, Setting, and Participants : This cohort study assessed [...]
Mené sur 88 patients atteints d'un cancer et recevant des soins palliatifs, cet essai randomisé évalue l'efficacité d'un bain de bouche à base d'une solution de thé de Salvia Officinalis (sauge) pour soulager l'inconfort buccal et améliorer leur santé buccale
A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial
Mené sur 88 patients atteints d'un cancer et recevant des soins palliatifs, cet essai randomisé évalue l'efficacité d'un bain de bouche à base d'une solution de thé de Salvia Officinalis (sauge) pour soulager l'inconfort buccal et améliorer leur santé buccale
A mouth rinse based on a tea solution of Salvia officinalis for oral discomfort in palliative cancer care: a randomized controlled trial
Monsen, Ragnhild Elisabeth ; Herlofson, Bente Brokstad ; Gay, Caryl ; Fjeld, Katrine Gahre ; Hove, Lene Hystad ; Malterud, Karl Egil ; Saghaug, Elisabeth ; Slaaen, Joran ; Sundal, Tone ; Tollisen, Anita ; Lerdal, Anners
Background : Few clinical studies evaluate interventions to reduce oral discomfort among patients in palliative care. Aim : This study examines the efficacy of a Salvia officinalis (SO) based herbal mouth rinse compared to conventional normal saline (NS) in order to improve oral health. Design : A block-randomized controlled trial. Data were collected before and after a 4-day intervention with either SO (n=44) or NS (n=44). Numerical rating scales (NRS, 0–10) and 12 items from the European [...]
A partir d'une revue de la littérature (16 essais randomisés), cette méta-analyse évalue l'efficacité de la glutamine pour prévenir ou traiter une mucite buccale induite par la chimiothérapie ou la radiothérapie chez des patients atteints d'un cancer
Effectiveness of glutamine in the management of oral mucositis in cancer patients: a meta-analysis of randomized controlled trials
A partir d'une revue de la littérature (16 essais randomisés), cette méta-analyse évalue l'efficacité de la glutamine pour prévenir ou traiter une mucite buccale induite par la chimiothérapie ou la radiothérapie chez des patients atteints d'un cancer
Effectiveness of glutamine in the management of oral mucositis in cancer patients: a meta-analysis of randomized controlled trials
Peng, Tzu-Rong ; Lin, Hung-Hong ; Yang, Li-Jou ; Wu, Ta-Wei
Objective : The aim of this meta-analysis was to evaluate the effectiveness of glutamine for preventing or treating moderate-to-severe oral mucositis induced by chemotherapy or radiation therapy in patients with cancer. Methods : PubMed, Cochrane Library, and Embase were searched for eligible randomized controlled trials (RCTs) up to June 2020. The outcomes analyzed were oral mucositis (at all levels of severity). Data were pooled using the random-effects model and are expressed as risk ratios [...]
A partir d'une revue de la littérature publiée entre 2005 et 2020, cette étude analyse l'intérêt des interventions de soins de support destinées aux patients ayant survécu à un cancer colorectal et/ou à leurs aidants
A literature review of post-treatment survivorship interventions for colorectal cancer survivors and/or their caregivers
A partir d'une revue de la littérature publiée entre 2005 et 2020, cette étude analyse l'intérêt des interventions de soins de support destinées aux patients ayant survécu à un cancer colorectal et/ou à leurs aidants
A literature review of post-treatment survivorship interventions for colorectal cancer survivors and/or their caregivers
LUO, Xingjuan ; LI, Jieyu ; CHEN, Meizhen ; GONG, Jiali ; Xu, Yongyong ; Li, Qiuping
Objective : Colorectal cancer (CRC) survivors have reported a number of concerns and unmet needs after treatment completion. This paper aims to explore existing survivorship interventions after CRC treatment according to the American Cancer Society CRC Survivorship Care Guidelines, to identify study gaps, and provide valuable evidence directing future research. Methods : Five electronic databases, including CINAHL, PsycINFO, Embase, PubMed, and Cochrane Library databases from 2005 to October [...]
Menée en Chine auprès de 79 patients atteints d'un carcinome du rhinopharynx, cette étude prospective analyse les facteurs associés à la présence et à la sévérité d'une fatigue pendant et après une chimioradiothérapie
Multidimensional fatigue in patients with nasopharyngeal carcinoma receiving concurrent chemoradiotherapy: incidence, severity, and risk factors
Menée en Chine auprès de 79 patients atteints d'un carcinome du rhinopharynx, cette étude prospective analyse les facteurs associés à la présence et à la sévérité d'une fatigue pendant et après une chimioradiothérapie
Multidimensional fatigue in patients with nasopharyngeal carcinoma receiving concurrent chemoradiotherapy: incidence, severity, and risk factors
Chen, Lin-Min ; Yang, Qiu-Lan ; Duan, Yu-Yu ; Huan, Xue-Zhen ; He, Yan ; Wang, Cong ; Fan, Yu-ying ; Cai, Yu-Cong ; Li, Jian-Mei ; Chen, Li-Ping ; Qin, Hui-Ying
Purpose : To explore the incidence, severity, and risk factors of multidimensional fatigue in patients with nasopharyngeal carcinoma (NPC) receiving concurrent chemoradiotherapy (CCRT). Methods : This prospective study included 79 patients with NPC in Guangzhou (China) from June 2015 to July 2018. Data were collected before and after CCRT, including demographic and clinical characteristics, nutritional parameters, and fatigue scores, based on completion of the Multiple Dimensional Inventory-20 [...]
Menée à partir de données portant sur 55 patients atteints d'un cancer de l'oropharynx ou de la cavité buccale, cette étude rétrospective analyse l'intérêt d'une intervention de réadaptation pour traiter une dysphagie et les troubles de la déglutition pendant la radiothérapie adjuvante dispensée après le traitement chirurgical
Impact of rehabilitation treatment on swallowing during adjuvant radiotherapy following surgery in patients with oral and oropharyngeal cancer
Menée à partir de données portant sur 55 patients atteints d'un cancer de l'oropharynx ou de la cavité buccale, cette étude rétrospective analyse l'intérêt d'une intervention de réadaptation pour traiter une dysphagie et les troubles de la déglutition pendant la radiothérapie adjuvante dispensée après le traitement chirurgical
Impact of rehabilitation treatment on swallowing during adjuvant radiotherapy following surgery in patients with oral and oropharyngeal cancer
Hashida, Nao ; Tamiya, Hironari ; Fujii, Takashi
Background : Patients with advanced oral or oropharyngeal cancer sometimes require surgery and adjuvant postoperative radiotherapy (PORT), which may cause dysphagia. However, the efficacy of rehabilitation treatment for PORT-induced dysphagia remains unclear. This study aimed to determine whether rehabilitation treatment during PORT after surgery is effective for dysphagia. Methods : We retrospectively studied 55 patients with oral or oropharyngeal cancer who received PORT. Of these, 25 [...]
Observation (3)
Menée aux Etats-Unis par enquête auprès de 7 007 adultes âgés de plus de 40 ans (âge moyen : 55,4 ans), cette étude de cohorte analyse l'association entre le fait de sauter le petit-déjeuner et la mortalité par cancer et toutes causes confondues
The association of skipping breakfast with cancer-related and all-cause mortality in a national cohort of United States adults
Menée aux Etats-Unis par enquête auprès de 7 007 adultes âgés de plus de 40 ans (âge moyen : 55,4 ans), cette étude de cohorte analyse l'association entre le fait de sauter le petit-déjeuner et la mortalité par cancer et toutes causes confondues
The association of skipping breakfast with cancer-related and all-cause mortality in a national cohort of United States adults
Helo, Dena ; Appiah, Linda ; Bhende, Kishor M. ; Byrd, Theresa L. ; Appiah, Duke
Purpose : Many lifestyle and dietary factors have been recognized as risk factors for cancer morbidity and mortality. However, investigations of the association of the frequency of breakfast consumption and cancer are limited. This study aimed to examine the association of skipping breakfast with all-cause and cancer-related mortality in a national cohort of United States men and women. Methods : Data were from 7,007 adults aged ≥ 40 years who participated in the third National Health and [...]
Menée à partir des données de 43 pays, cette étude analyse les disparités géographiques dans l'évolution de l'incidence du cancer du poumon, sur la période 1978-2012
Global patterns and trends in lung cancer incidence: a population-based study
Menée à partir des données de 43 pays, cette étude analyse les disparités géographiques dans l'évolution de l'incidence du cancer du poumon, sur la période 1978-2012
Global patterns and trends in lung cancer incidence: a population-based study
Zhang, Yanting ; Luo, Ganfeng ; Etxeberria, Jaione ; Hao, Yuantao
Background : Lung cancer (LC) has been the most common cancer worldwide for several decades. This study comprehensively examined recent geographical patterns and temporal trends in LC incidence from 1978 to 2012 in 43 countries and evaluated the effects of birth cohort and period on temporal trends. Methods : Data were retrieved from the Cancer Incidence in Five Continents database. Joinpoint regression and age-period-cohort models were applied. Results : The age-standardized rate (ASR) was [...]
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Experiences of people affected by cancer during the outbreak of the COVID-19 pandemic: an exploratory qualitative analysis of public online forums
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Experiences of people affected by cancer during the outbreak of the COVID-19 pandemic: an exploratory qualitative analysis of public online forums
Colomer-Lahiguera, Sara ; Ribi, Karin ; Dunnack, Hayley J. ; Cooley, Mary E. ; Hammer, Marilyn J. ; Miaskowski, Christine ; Eicher, Manuela
Purpose : Studies focusing on patients with and survivors of cancer during the COVID-19 pandemic highlight unique psychological and behavioral challenges. These findings were obtained in surveys using self-report questionnaires with pre-specified response options that may not capture the broad range of experiences of individuals affected by cancer, including people with cancer and informal caregivers, in this unprecedented situation. Online forums produce a large amount of valuable first-hand [...]
COVID concerns highlight the importance of adequate fecal immunochemical test sample collection
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
COVID concerns highlight the importance of adequate fecal immunochemical test sample collection
Fillon, Mike
Recent surveys suggest that many people, concerned about contracting coronavirus disease 2019 (COVID‐19) through public exposure, have been forgoing cancer screening tests. (The American Society of Clinical Oncology, for example, found that approximately two‐thirds of those who were scheduled to receive cancer screenings during the pandemic reported missing or delaying them.) Although fecal occult blood tests, including FIT, that can be performed at home offer a good solution for most [...]
The ESMO Call to Action on COVID-19 vaccinations and patients with cancer: Vaccinate. Monitor. Educate
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
The ESMO Call to Action on COVID-19 vaccinations and patients with cancer: Vaccinate. Monitor. Educate
Garassino, Marina Chiara ; Vyas, Malvika ; de Vries, Elisabeth ; Kanesvaran, Ravindran ; Giuliani, Rosa ; Peters, Solange
March 11, 2021 marks the first anniversary of a pandemic that has pushed the world into shutdown. Of a global population of almost 8 billion, COVID-19 has affected more than a hundred million people, with over 2 million deaths.1 However, the magnitude of its impact has been heterogeneous, with some groups, including patients with cancer, being more severely affected than others. With initially limited understanding of this infectious disease transmitted by a coronavirus strain, SARS-CoV-2, the [...]
2021 Update of the AGIHO guideline on evidence-based management of COVID-19 in cancer patients regarding diagnostics, viral shedding, vaccination a...
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
2021 Update of the AGIHO guideline on evidence-based management of COVID-19 in cancer patients regarding diagnostics, viral shedding, vaccination and therapy
Giesen, Nicola ; Sprute, Rosanne ; Rüthrich, Maria ; Khodamoradi, Yascha ; Mellinghoff, Sibylle C. ; Beutel, Gernot ; Lueck, Catherina ; Koldehoff, Michael ; Hentrich, Marcus ; Sandherr, Michael ; von Bergwelt-Baildon, Michael ; Wolf, Hans-Heinrich ; Hirsch, Hans H. ; Wörmann, Bernhard ; Cornely, Oliver A. ; Köhler, Philipp ; Schalk, Enrico ; von Lilienfeld-Toal, Marie
The worldwide spread of SARS-CoV-2 and the associated infectious disease COVID-19 has posed a unique challenge to medical staff, patients and their families. Cancer patients, particularly those with haematologic malignancies, have been identified to be at high risk to develop severe COVID-19. Since publication of our previous guideline on evidence-based management of COVID-19 in cancer patients, research efforts have continued and new relevant data has come to light, maybe most importantly in [...]
Public understanding of COVID-19 antibody testing and test results: A qualitative study conducted in the U.K. early in the pandemic
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Public understanding of COVID-19 antibody testing and test results: A qualitative study conducted in the U.K. early in the pandemic
Lecouturier, Jan ; Kelly, Michael P. ; Graham, Fiona ; Meyer, Carly ; Tang, Mei Yee ; Goffe, Louis ; Bonell, Chris ; Michie, Susan ; Sniehotta, Falko F.
Background : During the COVID-19 pandemic, antibody testing was proposed by several countries as a surveillance tool to monitor the spread of the virus and potentially to ease restrictions. In the UK, antibody testing originally formed the third pillar of the UK Government’s COVID-19 testing programme and was thought to offer hope that those with a negative antibody test result could return to normal life. However, at that time scientists and the public had little understanding of the longevity [...]
Systematic screening of COVID-19 disease based on chest CT and RT-PCR for cancer patients undergoing radiotherapy in a coronavirus French hotspot
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Systematic screening of COVID-19 disease based on chest CT and RT-PCR for cancer patients undergoing radiotherapy in a coronavirus French hotspot
Sun, Roger ; Achkar, Samir ; Ammari, Samy ; Bockel, Sophie ; Gallois, Emmanuelle ; Bayle, Arnaud ; Battistella, Enzo ; Salviat, Flore ; Merad, Mansouria ; Laville, Adrien ; Ka, Kanta ; Griscelli, Franck ; Albiges, Laurence ; Barlesi, Fabrice ; Bossi, Alberto ; Rivera, Sofia ; Chargari, Cyrus ; Deutsch, Eric
Background : Cancer patients are presumed to be more vulnerable to COVID-19. We evaluated a screening strategy combining chest computed-tomography (CT) and reverse transcription polymerase chain reaction (RT-PCR) for patients treated with radiotherapy (RT) in our cancer center located in a COVID-19 French hotspot during the first wave of the pandemic. Methods : Chest CT images were proposed during the radiotherapy CT simulation. Images were reviewed by an expert radiologist according to the [...]
Health-related quality of life of hospitalized COVID-19 survivors: an initial exploration in Nanning City, China
Ce dossier présente un ensemble d'articles concernant la prise en charge des cancers durant la crise sanitaire liée au COVID-19
Health-related quality of life of hospitalized COVID-19 survivors: an initial exploration in Nanning City, China
Wu, Chenhui ; Cheng, Jianquan ; Zou, Jun ; Duan, Lian ; Campbell, Janis E.
Understanding the health-related quality of life (HrQoL) of hospitalized COVID-19 survivors is an emerging global challenge arising from the current pandemic. A qualitative study of the experiences of sixteen hospitalized COVID-19 survivors from Nanning City, China, was conducted using semi-structured telephone interviews in May 2020. These first-hand accounts were critically and empirically analysed to identify emerging health and social issues, and provide potential solutions to improve [...]
Approches psycho-sociales (2)
Menée en Angleterre, cette étude analyse les besoins en soins de support de nature psycho-sociale chez des patients atteints d'un cancer ou ayant survécu à la maladie (âge : plus de 50 ans)
Unmet social care needs of people living with and beyond cancer: prevalence and predictors from an English longitudinal survey
Menée en Angleterre, cette étude analyse les besoins en soins de support de nature psycho-sociale chez des patients atteints d'un cancer ou ayant survécu à la maladie (âge : plus de 50 ans)
Unmet social care needs of people living with and beyond cancer: prevalence and predictors from an English longitudinal survey
Gousia, Katerina ; Towers, Ann-Marie
Objectives : This study estimates the prevalence of unmet social care needs of people over 50 living in England with cancer and the effect of cancer on unmet needs. Methods : We used data from the English Longitudinal Study of Ageing. We estimated the mean, standard deviation and 95% CI of the prevalence of unmet social care needs among people with cancer. Logistic regression analysis with individual random effects was used to estimate the effect of cancer on unmet needs controlling for other [...]
Menée en Corée auprés de 141 patients atteints d'un myélome multiple réfractaire ou récidivant, cette étude de cohorte analyse l'effet d'une dépression sur l'adhésion à un traitement anticancéreux combinant lénalidomide et faibles doses de dexaméthasone
Impact of depression on adherence to lenalidomide plus low-dose dexamethasone in patients with relapsed or refractory myeloma
Menée en Corée auprés de 141 patients atteints d'un myélome multiple réfractaire ou récidivant, cette étude de cohorte analyse l'effet d'une dépression sur l'adhésion à un traitement anticancéreux combinant lénalidomide et faibles doses de dexaméthasone
Impact of depression on adherence to lenalidomide plus low-dose dexamethasone in patients with relapsed or refractory myeloma
Kim, Seok Jin ; Kang, Danbee ; Park, Yong ; Mun, Yeung-Chul ; Kim, Kihyun ; Kim, Jin Seok ; Min, Chang-Ki ; Cho, Juhee
Purpose : While continued lenalidomide and low-dose dexamethasone (Rd) treatment could improve survival outcomes for multiple myeloma (MM), the association of depression on the adherence to Rd regimen in myeloma patients has never been studied even though depression is a common symptom among MM patients. This study aims to evaluate the impact of depression prior to Rd treatment on adherence to the treatment among patients with MM. Methods : This multicenter cohort study was conducted from [...]
Analyses économiques et systèmes de soins (1)
Menée au Canada à partir de données portant sur 575 jeunes adultes ayant survécu à un cancer et sur 575 témoins, cette étude analyse l'impact financier de la maladie, en prenant notamment en compte les coûts restant à charge du patient et les périodes sans activité professionnelle
The financial impact of cancer on Canadian young adults
Menée au Canada à partir de données portant sur 575 jeunes adultes ayant survécu à un cancer et sur 575 témoins, cette étude analyse l'impact financier de la maladie, en prenant notamment en compte les coûts restant à charge du patient et les périodes sans activité professionnelle
The financial impact of cancer on Canadian young adults
Mahon, Kaitlyn N. ; Garland, Sheila N. ; Eaton, Geoff ; Chalifour, Karine ; Lane, Breanna E. ; Fowler, Ken ; Gambin, Lynn ; Clair, Luc
Purpose : To explore the financial impact of cancer in young adults (YAs) compared to matched non-cancer peers. Methods : Five hundred seventy-five YAs from the Young Adults with Cancer in their Prime (YACPRIME) study reported on out-of-pocket cancer costs and missed work. YA cancer survivors were compared to matched peers without cancer on key financial indices based on current age (< 35 vs. 35 + years) and time since diagnosis (< 5 vs. 5 + years). Descriptive statistics, Chi-square tests, and [...]
Sensibilisation et communication (1)
Menée aux Etats-Unis auprès de 104 patients ayant survécu à un cancer colorectal, cette étude analyse l'association entre leurs difficultés financières et leur capacité à chercher et comprendre l'information concernant l'assurance maladie et les données relatives aux coûts médicaux
The association of health insurance literacy and numeracy with financial toxicity and hardships among colorectal cancer survivors
Menée aux Etats-Unis auprès de 104 patients ayant survécu à un cancer colorectal, cette étude analyse l'association entre leurs difficultés financières et leur capacité à chercher et comprendre l'information concernant l'assurance maladie et les données relatives aux coûts médicaux
The association of health insurance literacy and numeracy with financial toxicity and hardships among colorectal cancer survivors
Edward, Jean S. ; Rayens, Mary Kay ; Zheng, Xiaomei ; Vanderpool, Robin C.
Purpose : In this study, we examined the association of financial hardship measured by material financial burden and financial toxicity with health insurance literacy and numeracy among colorectal cancer survivors. The lack of evidence on the impact of cost-related health literacy, specifically health insurance literacy and numeracy, on financial toxicity among cancer survivors warrants further research. Methods : Between January and November 2019, we used a cross-sectional research design to [...]
Soins palliatifs (2)
Menée au Japon auprès de 38 patients âgés atteints d'un cancer et recevant des soins palliatifs (âge moyen : 75 ans), cette étude prospective analyse l'efficacité de faibles doses de trazodone pour réduire la sévérité d'un délire
Low-Dose Trazodone for Delirium in Patients with Cancer Who Received Specialist Palliative Care: A Multicenter Prospective Study
Menée au Japon auprès de 38 patients âgés atteints d'un cancer et recevant des soins palliatifs (âge moyen : 75 ans), cette étude prospective analyse l'efficacité de faibles doses de trazodone pour réduire la sévérité d'un délire
Low-Dose Trazodone for Delirium in Patients with Cancer Who Received Specialist Palliative Care: A Multicenter Prospective Study
Maeda, Isseki ; Inoue, Shinichiro ; Uemura, Keiichi ; Tanimukai, Hitoshi ; Hatano, Yutaka ; Yokomichi, Naosuke ; Amano, Koji ; Tagami, Keita ; Yoshiuchi, Kazuhiro ; Ogawa, Asao ; Iwase, Satoru ; Achatz, Eric ; Abo, Hirofumi ; Akechi, Tatsuo ; Akizuki, Nobuya ; Fujisawa, Daisuke ; Hagiwara, Shingo ; Hirohashi, Takeshi ; Hisanaga, Takayuki ; Imai, Kengo ; Inada, Shuji ; Inoue, Satoshi ; Iwata, Aio ; Kaneishi, Keisuke ; Kumano, Akifumi ; Matsuda, Yoshinobu ; Matsui, Takashi ; Matsumoto, Yoshihisa ; Matsuo, Naoki ; Miyajima, Kaya ; Mori, Ichiro ; Morita, Sachiyo ; Nakahara, Rika ; Nakajima, Nobuhisa ; Nobata, Hiroyuki ; Odagiri, Takuya ; Okuyama, Toru ; Sakashita, Akihiro ; Shimizu, Ken ; contrib, contrib ; Watanabe, Yuki Sumazaki ; Takeuchi, Emi ; Takeuchi, Mari ; Tatara, Ryohei ; Tokoro, Akihiro ; Uchida, Megumi ; Watanabe, Hiroaki ; Yabuki, Ritsuko ; Yamauchi, Toshihiro
Background: Clinical usefulness of trazodone for delirium in patients receiving palliative care is unclear. Objectives: To examine the safety and effectiveness of trazodone for delirium. Design: A secondary analysis of a multicenter prospective observational study. Setting/Subjects: The setting involves nine psycho-oncology consultation services and 14 inpatient palliative care units in Japan. Measurements: The measurement involves the Delirium Rating Scale (DRS) Revised-98 for effectiveness [...]
Menée au Canada à partir de données portant sur des patients décédés d'un cancer, cette étude de cohorte analyse l'utilisation des soins dans leur dernier mois de vie (soins en hôpital ou soins de support à domicile) selon qu'ils aient reçu des soins palliatifs précocement (plus de 6 mois avant le décès) ou non
End-of-life outcomes with or without early palliative care: a propensity score matched, population-based cancer cohort study
Menée au Canada à partir de données portant sur des patients décédés d'un cancer, cette étude de cohorte analyse l'utilisation des soins dans leur dernier mois de vie (soins en hôpital ou soins de support à domicile) selon qu'ils aient reçu des soins palliatifs précocement (plus de 6 mois avant le décès) ou non
End-of-life outcomes with or without early palliative care: a propensity score matched, population-based cancer cohort study
Seow, Hsien ; Sutradhar, Rinku ; Burge, Fred ; McGrail, Kimberlyn ; Guthrie, Dawn M ; Lawson, Beverley ; Oz, Urun Erbas ; Chan, Kelvin ; Peacock, Stuart ; Barbera, Lisa
Objectives : To investigate whether cancer decedents who received palliative care early (ie, >6 months before death) and not-early had different risk of using hospital care and supportive home care in the last month of life. Design/setting : We identified a population-based cohort of cancer decedents between 2004 and 2014 in Ontario, Canada using linked administrative data. Analysis occurred between August 2017 to March 2019. Participants : We propensity-score matched decedents on receiving [...]
Ressources et infrastructures (Lutte contre les cancers) (1)
Menée en Italie auprès de 1 163 patients atteints d'un lymphome diffus à grandes cellules B (âge médian : 76 ans), cette étude prospective analyse l'intérêt d'un outil de prise en charge gériatrique au moment du diagnostic pour évaluer la survie globale
Simplified Geriatric Assessment in Older Patients With Diffuse Large B-Cell Lymphoma: The Prospective Elderly Project of the Fondazione Italiana Li...
Menée en Italie auprès de 1 163 patients atteints d'un lymphome diffus à grandes cellules B (âge médian : 76 ans), cette étude prospective analyse l'intérêt d'un outil de prise en charge gériatrique au moment du diagnostic pour évaluer la survie globale
Simplified Geriatric Assessment in Older Patients With Diffuse Large B-Cell Lymphoma: The Prospective Elderly Project of the Fondazione Italiana Linfomi
Francesco Merli ; Stefano Luminari ; Alessandra Tucci ; Annalisa Arcari ; Luigi Rigacci ; Eliza Hawkes ; Carlos S. Chiattone ; Federica Cavallo ; Giuseppina Cabras ; Isabel Alvarez ; Alberto Fabbri ; Alessandro Re ; Benedetta Puccini ; Allison Barraclough ; Marcia Torresan Delamain ; Simone Ferrero ; Sara Veronica Usai ; Angela Ferrari ; Emanuele Cencini ; Elsa Pennese ; Vittorio Ruggero Zilioli ; Dario Marino ; Monica Balzarotti ; Maria Christina Cox ; Manuela Zanni ; Alice Di Rocco ; Arben Lleshi ; Barbara Botto ; Stefan Hohaus ; Michele Merli ; Roberto Sartori ; Guido Gini ; Luca Nassi ; Gerardo Musuraca ; Monica Tani ; Chiara Bottelli ; Sofia Kovalchuk ; Francesca Re ; Leonardo Flenghi ; Annalia Molinari ; Giuseppe Tarantini ; Emanuela Chimienti ; Luigi Marcheselli ; Caterina Mammi ; Michele Spina
PURPOSE : To prospectively validate the use of a simplified geriatric assessment (sGA) at diagnosis and to integrate it into a prognostic score for older patients with diffuse large B-cell lymphoma (DLBCL). METHODS : We conducted the prospective Elderly Project study on patients with DLBCL older than 64 years who underwent our Fondazione Italiana Linfomi original geriatric assessment (oGA) (age, Cumulative Illness Rating Scale for Geriatrics, activities of daily living, and instrumental [...]
