Menée par enquêtes auprès de 12 167 participants, cette étude analyse l'utilisation de la cigarette électronique chez les étudiants de 14 à 17 ans dans sept villes de pays de l'Union Européenne (Pays-Bas, Portugal, Italie, Irlande, Allemangne, Belgique et Finlande)

Electronic cigarette use among 14- to 17-year-olds in Europe

Kinnunen, Jaana M ; Rimpelä, Arja H ; Lindfors, Pirjo L ; Clancy, Luke ; Alves, Joana ; Hoffmann, Laura ; Richter, Matthias ; Kunst, Anton E ; Lorant, Vincent

Studies comparing adolescent e-cigarette use in different countries are scarce. We study students’ e-cigarette and conventional cigarette ever-use, their social correlates and e-liquid use in seven EU countries.SILNE-R data (N=12 167, response rate 79.4%) of 14–17-year-olds from Amersfoort (NL), Coimbra (PT), Dublin (IR), Hanover (GE), Latina (IT), Namur (BE) and Tampere (FI) were used. E-cigarette and conventional cigarette ever-use, dual-use, type of e-liquid and social correlates were [...]

Menée aux Etats-Unis à partir de données d'enquêtes réalisées sur la période 2013-2018 et portant sur 17 318 fumeurs âgés de plus de 18 ans, cette étude analyse l'association entre une consommation de cigarettes mentholées et le sevrage tabagique ou la rechute

The Relationship between Menthol Cigarette Use, Smoking Cessation and Relapse: Findings from Waves 1 to 4 of the Population Assessment of Tobacco and Health Study

Mills, Sarah D ; Hao, Yajing ; Ribisl, Kurt M ; Wiesen, Christopher A ; Hassmiller Lich, Kristen

Some, but not all, studies suggest that menthol cigarette smokers have more difficulty quitting than non-menthol cigarette smokers. Inconsistent findings may be a result of differences in smoker characteristics (e.g. daily vs. non-daily smokers) across studies. This study examines the relationship between menthol cigarette use, cessation and relapse in a longitudinal, nationally representative study of tobacco use in the United States.Data come from four waves of the Population Assessment of [...]

Menée au Canada entre 2015 et 2018 auprès de 85 869 personnes, cette étude analyse la variation saisonnière des demandes de prise en charge pour le sevrage tabagique et de la réussite de ce sevrage

Seasonal variation in demand for smoking cessation treatment and clinical outcomes

Veldhuizen, Scott ; Zawertailo, Laurie ; Ivanova, Anna ; Hussain, Sarwar ; Selby, Peter

Smoking behaviour shows seasonal variation, with cigarette consumption and youth smoking onset highest in summer and smoking-related web searches and sales of nicotine replacement products highest in winter. Variation in demand for clinical care and in outcomes has not been explored.We measure seasonal variation in enrolments, total clinical visits, visits per enrolment, and treatment outcome (7-day abstinence at 6 month follow-up) from 2015 to 2018 in a large (n=85,869) clinical cohort from [...]

Après avoir listé les facteurs de risque connus de carcinome hépatique, cet article présente le rôle et les mécanismes d'action, pour la prévention et le traitement de la maladie, de produits à base de plantes et d'aliments naturels

Herbal and Natural Dietary Products: Upcoming Therapeutic Approach for Prevention and Treatment of Hepatocellular Carcinoma

Mandlik, Deepa S. ; Mandlik, Satish K.

The most common tumor linked with elevated death rates is considered the hepatocellular carcinoma (HCC), sometimes called the malignant hepatoma. The initiation and progression of HCC are triggered by multiple factors like long term alcohol consumption, metabolic disorders, fatty liver disease, hepatitis B and C infection, age, and oxidative stress. Sorafenib is the merely US Food and Drug Administration (FDA)-approved drug used to treat HCC. Several treatment methods are available for HCC [...]

Mené entre 2014 et 2017 sur 109 patients présentant des nodules pulmonaires non solides détectés par tomodensitométrie (âge moyen : 64,6 ans ; 43,8 % d'hommes ; 67,3 % de fumeurs), cet essai de phase IIb évalue l'efficacité, du point de vue de l'évolution de la taille des nodules, d'un traitement par faibles doses d'aspirine pendant 12 mois

Low-dose aspirin in high-risk individuals with screen-detected subsolid lung nodules: a randomized phase-II trial

Bonanni, Bernardo ; Serrano, Davide ; Maisonneuve, Patrick ; Veronesi, Giulia ; Johansson, Harriet ; Aristarco, Valentina ; Varricchio, Clara ; Cazzaniga, Massimiliano ; Lazzeroni, Matteo ; Rampinelli, Cristiano ; Bellomi, Massimo ; Vecchi, Manuela ; Spaggiari, Lorenzo ; Vornik, Lana ; Brown, Powel H ; Beavers, Therese B ; Guerrieri-Gonzaga, Aliana ; Szabo, Eva

Lung cancer screening by helical low-dose computed tomography (ld-CT) detects non-solid nodules that may be lung adenocarcinoma precursors. Aspirin’s anti-inflammatory properties make it an attractive target for prevention of multiple cancers, including lung cancer. Therefore, we conducted a phase IIb trial (NCT02169271) to study the efficacy of low-dose aspirin to reduce the size of subsolid lung nodules (SSNs). A total of 98 current or former smokers (67.3% current) undergoing annual ld-CT [...]

Menée aux Etats-Unis à partir de données 1999-2017 de plusieurs registres portant sur 97,8% de la population américaine, cette étude analyse l'évolution de l'incidence des cancers invasifs du col de l'utérus depuis l'introduction du vaccin contre le papillomavirus humain, en fonction de l'âge

Assessing Impact of HPV Vaccination on Cervical Cancer Incidence in Women 15-29 years in the United States, 1999-2017: An Ecologic Study

Mix, Jacqueline M ; Van Dyne, Elizabeth A ; Saraiya, Mona ; Hallowell, Benjamin D. ; Thomas, Cheryll C

Background: To date, the human papillomavirus (HPV) vaccine impact on invasive cervical cancers in the United States has not been documented due, in part, to the time needed for cancer to develop, and to recent changes to cervical cancer screening guidelines and recommendations which complicate data interpretation. Methods: We examined incidence rates of cervical squamous cell carcinoma (SCC) and adenocarcinoma (AC)among women aged 15-29 years diagnosed during 1999-2017 using population-based [...]

Cet article met en évidence les 3 axes de surveillance en santé publique pour l'élimination du cancer du col de l'utérus : la vaccination, le dépistage et le traitement

Surveillance systems for monitoring cervical cancer elimination efforts: Focus on HPV infection, cervical dysplasia, cervical screening and treatment

Brotherton, Julia M. L. ; Wheeler, Cosette ; Clifford, Gary ; Elfstrom, Miriam ; Saville, Marion ; Kaldor, John ; Machalek, Dorothy A.

In order to achieve the global elimination of cervical cancer as a public health problem, close surveillance of progress in the public health and clinical activities and outcomes across the three pillars of vaccination, screening and treatment will be required. Surveillance should ideally occur within an integrated system planned, funded, and regularly evaluated to ensure it is providing timely, accurate and relevant feedback for action. In this paper, we conceptualise the main public health [...]