Menée en Australie par questionnaire auprès de jeunes survivants d'un cancer (âge moyen : 23 ans ; âge au moment du diagnostic : de 15 à 25 ans), cette étude analyse leurs habitudes et préférences en matière d'exercices physiques, ainsi que leur qualité de vie

Adolescents and young adult cancer survivors: exercise habits, quality of life and physical activity preferences

Murnane, A. ; Gough, K. ; Thompson, K. ; Holland, L. ; Conyers, R.

Introduction : Given the decades of survivorship for adolescent and young adult (AYA) cancer survivors, it is important to promote behaviours that enhance physical and mental well-being and quality of life (QoL). The purpose of this study was to explore the exercise programming preferences and information needs of AYA survivors and to examine the impact of a cancer diagnosis on physical activity behavior and QoL. Methods : Participants aged 15–25 years at time of diagnosis and referred to a [...]

A partir des données de la cohorte "Childhood Cancer Survivor Study" incluant 1 187 survivants adultes d'un lymphome hodgkinien pédiatrique (âge médian : 31, 2 ans), cette étude analyse l'association entre la pratique d'exercices physiques et la survenue d'événements cardiovasculaires indésirables liés aux traitements

Exercise and Risk of Major Cardiovascular Events in Adult Survivors of Childhood Hodgkin Lymphoma: A Report From the Childhood Cancer Survivor Study

Jones, Lee W. ; Liu, Qi ; Armstrong, Gregory T. ; Ness, Kirsten K. ; Yasui, Yutaka ; Devine, Katie ; Tonorezos, Emily ; Soares-Miranda, Luisa ; Sklar, Charles A. ; Douglas, Pamela S. ; Robison, Leslie L. ; Oeffinger, Kevin C.

Purpose : Survivors of Hodgkin lymphoma (HL) are at increased risk of treatment-related cardiovascular (CV) events; whether exercise modifies this risk is unknown. Methods : Survivors of HL (n = 1,187; median age, 31.2 years) completed a questionnaire evaluating vigorous-intensity exercise behavior. CV events were collected in follow-up questionnaires and graded according to Common Terminology Criteria for Adverse Events (version 4.03). The primary end point was incidence of any major (grade 3 [...]

Menée aux Etats-Unis auprès de 136 femmes ayant survécu à un cancer du sein après la ménopause, cette étude évalue l'association entre leur activité physique mesurée de façon objective et leurs fonctions cognitives

Objectively measured physical activity and cognitive functioning in breast cancer survivors

Marinac, CatherineR ; Godbole, Suneeta ; Kerr, Jacqueline ; Natarajan, Loki ; Patterson, RuthE ; Hartman, SheriJ

Purpose : This study aimed to explore the relationship between objectively measured physical activity and cognitive functioning in breast cancer survivors. Methods : Participants were 136 postmenopausal breast cancer survivors. Cognitive functioning was assessed using a comprehensive computerized neuropsychological test. Seven-day physical activity was assessed using hip-worn accelerometers. Linear regression models examined associations of minutes per day of physical activity at various [...]

Menée en Australie par enquête auprès de 629 patientes atteintes d'un cancer de l'endomètre, cette étude analyse leurs besoins en soins de support 3 à 5 ans après le diagnostic

Prevalence, predictors, and correlates of supportive care needs among women 3–5 years after a diagnosis of endometrial cancer

Rowlands, IngridJ ; Janda, Monika ; McKinnon, Loretta ; Webb, PenelopeM ; Beesley, VanessaL

Purpose : The purpose of this study is to examine the prevalence, sociodemographic and clinical predictors, and physical and psychosocial correlates of unmet needs among women 3–5 years following treatment for endometrial cancer. Methods : Women with endometrial cancer completed a survey around the time of diagnosis and again 3–5 years later. The follow-up survey asked women about their physical and psychosocial functioning and supportive care needs (CaSUN). Multivariable-adjusted logistic [...]

A partir d'une revue systématique de la littérature (51 études), cette étude passe en revue les différents problèmes rencontrés par les patients atteints de cancer et traités par chimiothérapie

Treatment-related problems experienced by cancer patients undergoing chemotherapy: a scoping review

Wagland, R. ; Richardson, A. ; Armes, J. ; Hankins, M. ; Lennan, E. ; Griffiths, P.

Cancer patients undergoing chemotherapy experience a range of treatment-related problems, and variations in prevalence exist between treatment centres. A scoping review was undertaken to map reported rates of problem prevalence in the literature. This will inform development of a patient-reported outcome measure (PROM) to monitor prevalence and severity of problems over time and assist service providers optimise supportive care provision. Two databases (Embase and Medline) were searched from [...]

Cet article présente les principales données de la base "Globocan" 2012 en matière d'incidence et de mortalité par cancer dans 20 grandes régions du monde

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

Ferlay, Jacques ; Soerjomataram, Isabelle ; Dikshit, Rajesh ; Eser, Sultan ; Mathers, Colin ; Rebelo, Marise ; Parkin, Donald Maxwell ; Forman, David ; Bray, Freddie

Estimates of the worldwide incidence and mortality from 27 major cancers and for all cancers combined for 2012 are now available in the GLOBOCAN series of the International Agency for Research on Cancer. We review the sources and methods used in compiling the national cancer incidence and mortality estimates, and briefly describe the key results by cancer site and in 20 large “areas” of the world. Overall, there were 14.1 million new cases and 8.2 million deaths in 2012. The most commonly [...]

Cette étude analyse l'évolution de l'incidence du cancer du sein à Hong Kong, ainsi que la mortalité spécifique, sur la période 1976-2010

Breast cancer incidence and mortality in a transitioning Chinese population: current and future trends

Wong, I. O. L. ; Schooling, C. M. ; Cowling, B. J. ; Leung, G. M.

Background: Projections of future trends in cancer incidence and mortality are important for public health planning. Methods: By using 1976–2010 data in Hong Kong, we fitted Poisson age-period-cohort models and made projections for future breast cancer incidence and mortality to 2025. Results: Age-standardised breast cancer incidence (/mortality) is projected to increase (/decline) from 56.7 (/9.3) in 2011–2015 to 62.5 (/8.6) per 100 000 women in 2021–2025. Conclusions: The incidence pattern [...]

Cet article présente les données de l'Organisation Mondiale de la Santé en matière d'incidence du cancer de la thyroïde et de la mortalité sur la période 1970-2012

Thyroid cancer mortality and incidence: A global overview

La Vecchia, Carlo ; Malvezzi, Matteo ; Bosetti, Cristina ; Garavello, Werner ; Bertuccio, Paola ; Levi, Fabio ; Negri, Eva

In most areas of the world, thyroid cancer incidence has been appreciably increasing over the last few decades, whereas mortality has steadily declined. We updated global trends in thyroid cancer mortality and incidence using official mortality data from the World Health Organization (1970–2012) and incidence data from the Cancer Incidence in Five Continents (1960–2007). Male mortality declined in all the major countries considered, with annual percent changes around −2/−3% over the last [...]

Menée aux Pays-Bas auprès de 174 patients pédiatriques atteints de cancer, cette étude analyse les facteurs associés à leur participation à des interventions de nature physique ou psychologique

Factors influencing childhood cancer patients to participate in a combined physical and psychosocial intervention program: Quality of Life in Motion

van Dijk-Lokkart, Elisabeth M. ; Braam, Katja I. ; Huisman, Jaap ; Kaspers, Gertjan J. L. ; Takken, Tim ; Veening, Margreet A. ; Bierings, Marc ; Merks, Johannes H. ; Grootenhuis, Martha A. ; van den Heuvel-Eibrink, Marry ; Streng, Isabelle C. ; van Dulmen-den Broeder, Eline

Background : For a multi-center randomized trial investigating the effects of a 12-week physical and psychosocial intervention program for children with cancer, we invited 174 patients (8–18 years old) on treatment or within 1 year after treatment; about 40% participated. Reasons for non-participation were investigated. Methods : Eligible patients received written and verbal information about the study. Those declining to participate were asked to complete questionnaires concerning: reasons for [...]

Menée en Suisse auprès de 62 participants, cette étude analyse l'efficacité d'une intervention psychologique pour améliorer la qualité de vie de survivants d'un cancer après une greffe de cellules souches hématopoïétiques

A mindfulness-based program for improving quality of life among hematopoietic stem cell transplantation survivors: feasibility and preliminary findings

Grossman, Paul ; Zwahlen, Diana ; Halter, JorgP ; Passweg, JakobR ; Steiner, Claudia ; Kiss, Alexander

Health-related quality of life (HRQoL) is often substantially reduced among individuals who have undergone hematopoietic stem cell transplantation (HSCT), and incidences of depression, fatigue, and anxiety are elevated. We examined effects of a mindfulness-based intervention (MBI) compared to psycho-oncological telephone consultation upon HRQoL, depression, anxiety, and fatigue among HSCT survivors. Sixty-two medically stable patients participated in the study; they had completed HSCT ≥6 months [...]

Menée en Indonésie par enquête auprès de 120 aidants familiaux, cette étude analyse les facteurs associés à leur implication dans les soins apportés à un patient hospitalisé atteint de cancer ainsi que leur qualité de vie

Family caregivers' involvement in caring for a hospitalized patient with cancer and their quality of life in a country with strong family bonds

Effendy, Christantie ; Vernooij-Dassen, Myrra ; Setiyarini, Sri ; Kristanti, Martina Sinta ; Tejawinata, Sunaryadi ; Vissers, Kris ; Engels, Yvonne

Background : Being involved in caring for family members during illness is part of the Indonesian culture, even during hospitalization. It is unknown which factors influence the quality of life (QoL) of family members taking care of their loved ones. The present study aims to identify factors influencing the QoL of family caregivers of hospitalized patients with cancer in Indonesia. Methods : A cross-sectional survey was performed. Data were collected in a general hospital in Yogyakarta from [...]

Cet article analyse les enjeux associés à un systéme de fixation du prix des médicaments anticancéreux en fonction de leur efficacité par pathologie

Indication-specific pricing for cancer drugs

Bach, P. B.

As policy makers consider how to handle high-priced drugs, an important concern is that the price of the drug is not currently linked to its benefits. “Value,” the benefit of a treatment with respect to its cost, has become an increasingly important consideration, following some explicit models in Europe, where value is considered although not directly integrated into pricing. The UK National Institute for Health and Care Excellence (NICE) makes formulary determinations by considering [...]

Menée au Canada par entretien téléphonique auprès de 15 patients atteints d'un cancer colorectal, cette étude qualitative analyse leurs perceptions du rôle du coordinateur du parcours de soins en milieu hospitalier urbain

Cancer patient experience with navigation service in an urban hospital setting: a qualitative study

Gotlib Conn, L. ; Hammond Mobilio, M. ; Rotstein, O. D. ; Blacker, S.

Cancer patient navigators are increasingly present on the oncology health care team. The positive impact of navigation on cancer care is recognised, yet a clear understanding of what the patient navigator does and how he/she executes the role continues to emerge. This study aimed to understand cancer patients’ perceptions of, and experiences with patient navigation, exploring how navigation may enhance the patient experience in an urban hospital setting where patients with varying needs are [...]

Menée en Suisse par enquête auprès de 1 013 professionnels de santé en oncologie, cette étude analyse leurs attitudes en matière de signalement d'erreurs médicales commises par des collègues et susceptibles de porter atteinte aux patients

Frequency of and predictors for withholding patient safety concerns among oncology staff: a survey study

Schwappach, D. L. B. ; Gehring, K.

Speaking up about patient safety is vital to avoid errors reaching the patient and to improve a culture of safety. This study investigated the prevalence of non-speaking up despite concerns for safety and aimed to identify predictors for withholding voice among healthcare professionals (HCPs) in oncology. A self-administered questionnaire assessed safety concerns, speaking up beliefs and behaviours among nurses and doctors from nine oncology departments. Multiple regression analysis was used to [...]