Breast cancer: The good, the bad, and an important call to effective risk reduction strategies

Cette étude présente les données 2024 de l'"American Cancer Society" concernant l'incidence du cancer du sein et la mortalité associée

Résumé en anglais

The 2024 Breast Cancer Statistics highlight a few interesting trends: breast cancer incidence is increasing, there is a greater increase in younger women, and most of this increase is driven by early stage diagnosis and hormone receptor (HR)-positive disease.1 In addition, compared with other racial groups, women with Asian American/Pacific Islander (AAPI) heritage have a greater increase in breast cancer; and, despite overall declining death rates from breast cancer, Black women continue to have higher mortality compared with White women. Let us consider these findings in more detail.

Breast cancer incidence in the United States briefly decreased in the early 2000s, possibly related to a decline in the use of hormone-replacement therapy, but it has since shown an increase of approximately 1% per year. This increase is associated with HR-positive breast cancers and is mostly seen in younger women. A potential contributing factor for this association may be a decrease in the number of live births.2 Another possibility may be the greater incidence of young-onset HR-positive breast cancer in Indian and Chinese women.3-5

AAPI women have a greater increase in breast cancer incidence, which is largely noted in Asian women immigrating to the United States rather than Asian women born in the United States.6 Compared with Asian American women born in the United States, Asian American women who have immigrated to the United States and have lived more than 50% of their life in the United States, on average, are three times more likely to be diagnosed with breast cancer.6 Specifically for Indian women, there has been a rise in breast cancer incidence by almost 50% between 1965 and 1985,4 and Chinese women are projected to have a rise in breast cancer incidence by greater than 11% by 2030