Menée aux Etats-Unis en 2018-2019 par enquête auprès de 137 471 participants (51,9 % de femmes ; âge moyen : 47,5 ans), cette étude analyse l'utilisation de la cigarette électronique en fonction de caractéristiques démographiques et du statut tabagique

Demographic Characteristics, Cigarette Smoking, and e-Cigarette Use Among US Adults

Mayer, Margaret ; Reyes-Guzman, Carolyn ; Grana, Rachel ; Choi, Kelvin ; Freedman, Neal D.

Understanding how electronic cigarettes (e-cigarettes) are used by current, former, and never cigarette smokers may inform public health actions and tobacco regulations. Therefore, we examined the distribution of e-cigarette use, also called vaping, in the 2018-2019 Tobacco Use Supplement to the Current Population Survey, the largest nationally representative tobacco use survey of US adults.

Menée à partir de données de la cohorte européenne EPIC portant sur 241 323 participants (31 % d'hommes ; durée de suivi : 8 ans), cette étude analyse l'association entre une variation du poids et/ou de l'indice de masse corporelle à l'âge adulte et le risque de cancer (42 localisations, 20 960 cas)

Weight change in middle adulthood and risk of cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort

Christakoudi, Sofia ; Pagoni, Panagiota ; Ferrari, Pietro ; Cross, Amanda J. ; Tzoulaki, Ioanna ; Muller, David C. ; Weiderpass, Elisabete ; Freisling, Heinz ; Murphy, Neil ; Dossus, Laure ; Fortner, Renée Turzanski ; Agudo, Antonio ; Overvad, Kim ; Perez-Cornago, Aurora ; Key, Timothy J. ; Brennan, Paul ; Johansson, Mattias ; Tjønneland, Anne ; Halkjær, Jytte ; Boutron-Ruault, Marie-Christine ; Artaud, Fanny ; Severi, Gianluca ; Kaaks, Rudolf ; Schulze, Matthias B. ; Bergmann, Manuela M. ; Masala, Giovanna ; Grioni, Sara ; Simeon, Vittorio ; Tumino, Rosario ; Sacerdote, Carlotta ; Skeie, Guri ; Rylander, Charlotta ; Borch, Kristin Benjaminsen ; Quirós, J. Ramón ; Rodriguez-Barranco, Miguel ; Chirlaque, María-Dolores ; Ardanaz, Eva ; Amiano, Pilar ; Drake, Isabel ; Stocks, Tanja ; Häggström, Christel ; Harlid, Sophia ; Ellingjord-Dale, Merete ; Riboli, Elio ; Tsilidis, Konstantinos K.

Obesity is a risk factor for several major cancers. Associations of weight change in middle adulthood with cancer risk, however, are less clear. We examined the association of change in weight and body mass index (BMI) category during middle adulthood with 42 cancers, using multivariable Cox proportional hazards models in the European Prospective Investigation into Cancer and Nutrition cohort. Of 241 323 participants (31% men), 20% lost and 32% gained weight (>0.4 to 5.0 kg/year) during [...]

Menée à partir de données des cohortes "the Nurses’ Health Studies" et "the Health Professionals Follow-Up Study" portant sur 43 163 personnes, cette étude analyse l'association entre une supplémentation en glucosamine et en chondroïtine et le risque de développer un adénome colorectal (5 715 cas) ou des polypes dentelés (4 954 cas)

Glucosamine and chondroitin supplements and risk of colorectal adenoma and serrated polyp

Lee, Dong Hoon ; Cao, Chao ; Zong, Xiaoyu ; Zhang, Xuehong ; O'Connell, Kelli ; Song, Mingyang ; Wu, Kana ; Du, Mengmeng ; Cao, Yin ; Giovannucci, Edward L. ; Kantor, Elizabeth D.

Background: Studies have shown an inverse association between use of glucosamine and chondroitin supplements and colorectal cancer risk. However, the association with the precursor lesion, colorectal adenoma and serrated polyp, has not been examined. Methods: Analyses include 43,163 persons from the Nurses' Health Study (NHS), Health Professionals Follow-up Study (HPFS), and NHS2 who reported on glucosamine/chondroitin use in 2002 and who subsequently underwent ≥1 lower gastrointestinal [...]

Menée aux Etats-Unis auprès de 3 080 femmes atteintes d'une pathologie bénigne du sein diagnostiquée entre 1992 et 2001 (âge moyen : 50,3 ans ; durée médiane de suivi : 16,4 ans), cette étude analyse l'association entre une utilisation d'anti-inflammatoires non stéroïdiens et le risque de cancer du sein (312 cas)

Breast Cancer Risk and Use of Nonsteroidal Anti-inflammatory Agents After a Benign Breast Biopsy

Sherman, Mark E. ; Vierkant, Robert A. ; Kaggal, Suneetha ; Hoskin, Tanya L. ; Frost, Marlene H. ; Denison, Lori ; Visscher, Daniel W. ; Carter, Jodi M. ; Winham, Stacey J. ; Jensen, Matthew R. ; Radisky, Derek C. ; Vachon, Celine M. ; Degnim, Amy C.

Over one million women in the United States receive biopsy diagnoses of benign breast disease (BBD) each year, which confer a 1.5–4.0-fold increase in breast cancer risk. Studies in the general population suggest that nonsteroidal anti-inflammatory agents (NSAID) lower breast cancer risk; however, associations among women with BBD are unknown. We assessed whether NSAID use among women diagnosed with BBD is associated with lower breast cancer risk. Participants included 3,080 women (mean age = [...]

Menée à l'aide de données 2008 portant sur 2 989 jeunes adultes dans 8 Etats américains (âge : de 18 à 26 ans), cette étude analyse la couverture vaccinale contre le papillomavirus humain en fonction de la zone d'habitation (rurale ou urbaine)

Rural-Urban Differences in Human Papillomavirus Vaccination Among Young Adults in 8 U.S. States

Lee, Minjee ; Gerend, Mary A. ; Adjei Boakye, Eric

Each year, nearly 44,000 new cancers attributable to human papillomavirus (HPV) infection are diagnosed in the U.S., approximately 79% of which could have been prevented by HPV vaccination. HPV vaccination is routinely recommended for all adolescents aged 11–12 years, with catch-up vaccination recommended through age 26 years. For unvaccinated adults aged 27–45 years, a shared clinical decision-making approach to HPV vaccination is recommended. HPV vaccination rates in the U.S. are suboptimal. [...]

Cet article fait le point sur les risques pour la santé et les enjeux réglementaires du vapotage aux Etats-Unis

E-Cigarettes: Matching Risks With Regulations

Friedman, Abigail S. ; Tam, Jamie

In 2019, e-cigarettes captured public attention as never before, with more than 2,600 cases of e-cigarette or vaping product use–associated lung injury (EVALI) and at least 57 U.S. deaths by early 2020. Local and state governments responded with bans on flavored e-cigarette sales. The U.S. Food and Drug Administration (FDA) later announced restrictions on sales of flavored e-cigarette cartridges. Yet these responses conflated the epidemic of youth e-cigarette use—largely attributed to [...]

Mené en Thaïlande sur 4 172 fumeurs employés dans 84 entreprises, cet essai randomisé compare l'efficacité, du point de vue de l'abstinence vérifiée biochimiquement, de plusieurs programmes d'aide au sevrage tabagique avec incitation financière

Incentive programmes for smoking cessation: cluster randomized trial in workplaces in Thailand

White, Justin S ; Lowenstein, Christopher ; Srivirojana, Nucharee ; Jampaklay, Aree ; Dow, William H

Objective: To compare several monetary incentive programmes for promoting smoking abstinence among employees who smoke at workplaces in a middle income country. Design: Parallel group, open label, assessor blinded, cluster randomized controlled trial. Setting: Large industrial workplaces in metropolitan Bangkok, Thailand. Participants: Employees who smoked cigarettes and planned to quit within six months recruited from 101 worksite clusters (84 different companies). Interventions: Worksites [...]