Mené sur 47 patients atteints d'un cancer (âge moyen : 53,9 ans), cet essai randomisé évalue l'efficacité de l'ajout de gingembre à un traitement prophylactique standard pour réduire les nausées et vomissements induits par une chimiothérapie à base de carboplatine et de paclitaxel

Effects of ginger adjunct to the standard prophylaxis on reducing carboplatin and paclitaxel-induced nausea vomiting: a randomized controlled study

Uthaipaisanwong, Apiradee ; Oranratanaphan, Shina ; Musigavong, Natdanai

Purpose : To determine effects of ginger on reducing the severity of nausea and/or vomiting among gynecologic cancer patients receiving a combined carboplatin-paclitaxel regimen. Methods : The research was a randomized, double-blinded, crossover, placebo-controlled trial. Participants were patients with gynecologic malignancies receiving carboplatin-paclitaxel chemotherapy at King Chulalongkorn Memorial Hospital. Either ginger (2 g per day) or placebo was prescribed in adjunct to standard [...]

A partir d'une revue systématique de la littérature (36 articles), cette étude présente la mise à jour des recommandations concernant l'utilisation de la cryothérapie pour traiter une mucite induite par les traitements, chez des patients atteints d'un cancer

Systematic review of oral cryotherapy for the management of oral mucositis in cancer patients and clinical practice guidelines

Correa, M. Elvira P. ; Cheng, Karis Kin Fong ; Chiang, Karen ; Kandwal, Abhishek ; Loprinzi, Charles L. ; Mori, Takehiko ; Potting, Carin ; Rouleau, Tanya ; Toro, Juan J. ; Ranna, Vinisha ; Vaddi, Anusha ; Peterson, Douglas E. ; Bossi, Paolo ; Lalla, Rajesh V. ; Elad, Sharon

Purpose : To update the 2013 Multinational Association of Supportive Care in Cancer/International Society of Oral Oncology (MASCC/ISOO) clinical practice guidelines on oral cryotherapy for the management of oral mucositis (OM) caused by cancer therapies. Methods : A systematic review was conducted by the Mucositis Study Group of MASCC/ISOO. The evidence for each intervention for specific cancer treatment modalities was assigned a level of evidence (LoE). The findings were added to the database [...]

Menée aux Etats-Unis à partir de données portant sur 1 702 patients ayant survécu à un cancer et en âge de travailler (âge : 25-64 ans), cette étude analyse la présence de douleurs chroniques liées à la maladie, puis analyse l'association entre leurs douleurs, leur qualité de vie et leur situation professionnelle

Chronic pain, health-related quality of life, and employment in working-age cancer survivors

Cox-Martin, Emily ; Anderson-Mellies, Amy ; Borges, Virginia ; Bradley, Cathy

Purpose : This study estimated the prevalence of cancer-related pain in working-age cancer survivors (age 25–64 years) and evaluated differences in demographic and clinical variables in those with and without pain. We also investigated the impact of cancer-related pain on health-related quality of life (HRQoL) and employment outcomes in this population. Methods : We used cross-sectional data from the 2016 Behavioral Risk Factor Surveillance System (BRFSS). Analyses were conducted with a sample [...]

A partir des données de 9 études incluant 462 patients atteints d'un cancer, cette étude analyse, en fonction de l'âge et du sexe du patient, la survenue d'événements indésirables liés à une administration de produits à base de fentanyl, à des doses proportionnelles au schéma opioïde, pour soulager des douleurs aiguës

Effects of age and gender in patients receiving doses of opioids for breakthrough pain proportional to background opioid doses

Mercadante, Sebastiano ; Restivo, Vincenzo ; Casuccio, Alessandra

Aim : To identify the role of age and gender in analgesic and adverse effects after administering fentanyl products for breakthrough pain (BT), given in doses proportional to opioid doses given for background pain. Methods : Data from nine studies, in which patients with BP were given fentanyl products in doses proportional to their basal opioid regimen, were analyzed. Results : A total 462 patients presenting 1905 episodes of BP were included in this analysis. In older patients, the decrease [...]

A partir d'une revue systématique de la littérature (9 études, 743 patientes), cette méta-analyse évalue les effets de l'exercice physique sur les symptômes musculo-squelettiques induits par les inhibiteurs de l'aromatase chez des patientes ayant survécu à un cancer du sein

The effect of exercise on aromatase inhibitor-induced musculoskeletal symptoms in breast cancer survivors :a systematic review and meta-analysis

Lu, Geling ; Zheng, Jin ; Zhang, Lei

Background : Evidence is mixed regarding the effect of exercise programs on improving musculoskeletal symptoms and quality of life. Previous meta-analyses have not focused specifically on the musculoskeletal symptoms. Therefore, this meta-analysis aimed to evaluate the effect of exercise on these outcomes in breast cancer survivors taking aromatase inhibitors. Methods : PubMed, CINAHL, EMBASE, Web of Science, Wan Fang, CNKI, VIP, and CBM were searched for randomized control trials or [...]

A partir d'une revue de la littérature (16 études), cette étude analyse les expériences et la qualité de vie de patients ayant survécu à un cancer du testicule

Men’s experiences of surviving testicular cancer: an integrated literature review

Alexis, Obrey ; Adeleye, Adeniyi O. ; Worsley, Aaron James

Purpose : To synthesise literature in order to elucidate the experiences of men who have survived testicular cancer and determine their quality of life following treatment. Methods : An integrated review sought appropriate literature by utilising a keyword search across seven databases. Retrieved studies were appraised for quality, with 2 qualitative, 12 quantitative and 2 mixed method studies deemed appropriate for this review. The data were extracted and aggregated into categories by way of a [...]

Menée au Brésil à partir de données de quatre enquêtes nationales réalisées entre 1989 et 2013 (âge : 25-69 ans), cette étude analyse l'association entre le statut socio-économique, caractérisé par le niveau d'éducation scolaire, et la prévalence du tabagisme, en fonction du sexe et de catégories d'âges

24-Year trends in educational inequalities in adult smoking prevalence in the context of a national tobacco control program: The case of Brazil

Bandi, Priti ; Chang, Virginia W. ; Sherman, Scott E. ; Silver, Diana

Brazil was a low and middle-income country (LMIC) in the late-1980s when it implemented a robust national tobacco-control program (NTCP) amidst rapid gains in national incomes and gender equality. We assessed changes in smoking prevalence between 1989 and 2013 by education level and related these changes to trends in educational inequalities in smoking. Data were from four nationally representative cross-sectional surveys (1989, n = 25,298; 2003 n = 3845; 2008 n = 28,938; 2013 n = 47,440, ages [...]

Menée aux Etats-Unis à partir de données 2006-2015, cette étude analyse les facteurs associés à des consultations dans des services d'urgence hospitaliers pour prendre en charge une overdose d'opioïdes chez des patients atteints d'un cancer (35 339 visites)

Emergency Department Visits for Opioid Overdoses Among Patients with Cancer

Jairam, Vikram ; Yang, Daniel X ; Yu, James B ; Park, Henry S

Background : Patients with cancer may be at risk of high opioid use due to physical and psychosocial factors, although little data exists to inform providers and policymakers. Our aim is to examine overdoses from opioids leading to emergency department (ED) visits among patients with cancer in the United States. Methods : The Healthcare Cost and Utilization Project Nationwide Emergency Department Sample (HCUP-NEDS) was queried for all adult cancer-related patient visits with a primary diagnosis [...]

Menée au Danemark à partir de données portant sur 5 185 hommes atteints d'un cancer des cellules germinales et sur 51 850 témoins, cette étude analyse les facteurs impliqués dans le risque de maladie cardiovasculaire et la mortalité associée, en lien avec un traitement par bléomycine-étoposide-cisplatine (durée médiane de suivi : 1,8 mois)

Cardiovascular Risk Factors and Disease After Male Germ Cell Cancer

Jakob Lauritsen ; Merete Kjaer Hansen ; Mikkel Bandak ; Michael Bay Kreiberg ; Julie Wang Skøtt ; Thomas Wagner ; Maria Gry Gundgaard Kier ; Niels Vilstrup Holm ; Mads Agerbæk ; Ramneek Gupta ; Christian Dehlendorff ; Klaus Kae Andersen ; Gedske Daugaard

PURPOSE : To analyze the risk of cardiovascular disease (CVD) after treatment of male germ cell cancer (GCC). METHODS : Clinical data were extracted from the Danish Testicular Cancer database. For each patient, 10 men matched on date of birth were identified in the Danish normal population by risk-set sampling. Cardiovascular risk factors, CVD, and associated deaths were identified in Danish registries. The association between treatment and outcomes was analyzed by separate Cox models for each [...]

Menée en France à partir de données portant sur 125 497 patients atteints d'un cancer et décédés en 2015 (âge moyen : 73 ans), cette étude analyse leur prise en charge pendant leur dernière année et dernier mois de vie (types de traitements reçus, durée d'hospitalisation, lieu du décès,...) et analyse les causes de décès

Cancer and end of life: the management provided during the year and the month preceding death in 2015 and causes of death in France

Melac, Audrey Tanguy ; Lesuffleur, Thomas ; Bousquet, Philippe-Jean ; Fagot-Campagna, Anne ; Gastaldi-Ménager, Christelle ; Tuppin, Philippe

Purpose : The management of cancer patients at the end of life in France and their causes of death are not well known. Methods : People managed for cancer in 2014–2015, who died in 2015 and who were covered by the national health insurance general scheme (77% of the French population) were selected from the national health data system in order to analyze the health care reimbursed during the year and the month before their death. Results : This study included 125,497 people (mean age 73 years, [...]

Menée à partir de données portant sur 367 patients atteints d'un cancer du pancréas et inclus dans un essai clinique prospectif, cette étude analyse l'association entre le statut marital et la survie globale ou la survie sans maladie

Marital Status and Overall Survival in Patients with Resectable Pancreatic Cancer: Results of an Ancillary Analysis of NRG Oncology/RTOG 9704

Reyngold, Marsha ; Winter, Kathryn A. ; Regine, William F. ; Abrams, Ross A. ; Safran, Howard ; Hoffman, John P. ; Mowat, Rex B. ; Hayes, John P. ; Kessel, Ivan L. ; DiPetrillo, Thomas ; Narayan, Samir ; Chen, Yuhchyau ; Ben‐Josef, Edgar ; Delouya, Guila ; Suh, John H. ; Meyer, Joshua ; Haddock, Michael G. ; Feldman, Marvin ; Gaur, Rakesh ; Yost, Kathleen ; Peterson, Richard A. ; Sherr, David L. ; Moughan, Jennifer ; Crane, Christopher H.

Background : Several registry‐based analyses suggested a survival advantage for married versus single patients with pancreatic cancer. The mechanisms underlying the association of marital status and survival are likely multiple and complex and, therefore, may be obscured in analyses generated from large population‐based databases. The goal of this research was to characterize this potential association of marital status with outcomes in patients with resected pancreatic cancer who underwent [...]

Menée à partir des données des registres américains des cancers portant sur 754 270 patientes atteintes d'un cancer du sein diagnostiqué entre 2000 et 2015, cette étude analyse les causes de décès (183 002 décès)

Causes of death after breast cancer diagnosis: A US population-based analysis

Afifi, Ahmed M. ; Saad, Anas M. ; Al-Husseini, Muneer J. ; Elmehrath, Ahmed Osama ; Northfelt, Donald W. ; Sonbol, Mohamad Bassam

Background : The focus on noncancer causes of death in patients with breast cancer (BC) remains superficial. The objective of the current study was to assess and quantify causes of death after BC diagnosis. Methods : In total, 754,270 women with BC in the United States who were diagnosed during 2000 through 2015 and retrieved from the Surveillance, Epidemiology, and End Results (SEER) program were studied. Standardized mortality ratios (SMRs) for causes of death were calculated. Results : Of [...]

A partir d'une revue de la littérature, cette étude présente une estimation de la prévalence et de l'incidence des cancers de la cavité buccale dans les pays à faibles et moyens revenus

Prevalence and incidence of oral cancer in low- and middle-income countries: A scoping review

Shrestha, Aamod D. ; Vedsted, Peter ; Kallestrup, Per ; Neupane, Dinesh

Introduction : Oral cancer is common cancer in many low- and middle-income countries (LMICs) with a low five-year survival rate. It is among the four most common types of cancer in South East Asia region. In South-Central Asia, lip and oral cavity cancer is the second most common cancer according to the specific cancer types. Methods : This scoping review intended to investigate published studies on the current prevalence and incidence of oral cancer in LMICs. The review was conducted applying [...]

Menée aux Etats-Unis à partir de données portant sur 13 363 patients atteints d'un carcinome épidermoïde de l'oropharynx lié à une infection par le papillomavirus humain (âge médian au diagnostic : 58 ans), cette étude analyse les facteurs associés à l'évolution des stratégies thérapeutiques sur la période 2010-2014

National treatment trends in human papillomavirus–positive oropharyngeal squamous cell carcinoma

Zhan, Kevin Y. ; Puram, Sidharth V. ; Li, Michael M. ; Silverman, Dustin A. ; Agrawal, Amit A. ; Ozer, Enver ; Old, Matthew O. ; Carrau, Ricardo L. ; Rocco, James W. ; Higgins, Kevin M. ; Enepekides, Danny J. ; Husain, Zain ; Kang, Stephen Y. ; Eskander, Antoine

Background : Human papillomavirus (HPV)–mediated oropharyngeal cancer (OPC) is associated with dramatically improved survival in comparison with HPV-negative OPC and can be successfully treated with surgical and nonsurgical approaches. National treatment trends for OPC were investigated with the National Cancer Data Base (NCDB). Methods : The NCDB was reviewed for primary HPV-mediated OPC in 2010-2014. Multivariable regression was used to identify predictors of both nonsurgical therapy and [...]

Menée aux Pays-Bas par questionnaire auprès de 98 patients ayant survécu à un cancer de l'œsophage, cette étude transversale analyse leur situation professionnelle et les difficultés rencontrées dans leur emploi après une œsophagectomie (durée médiane de suivi : 48 mois)

Do esophageal cancer survivors work after esophagectomy and do health problems impact their work? A cross-sectional study

Kingma, B. F. ; Rauwerdink, P. ; Brenkman, H. J. F. ; Ruurda, J. P. ; van Hillegersberg, R.

Purpose : This study aimed to evaluate the occupational status and work impediments due to health problems in long-term esophageal cancer survivors. Methods : The Short-Form Health and Labour Questionnaire (SF-HLQ) was sent to esophageal cancer survivors. Primary outcomes included the number of working esophageal cancer survivors and the patient-reported impact of health problems on work, as evaluated by the SF-HLQ. Patient and treatment characteristics were compared between survivors who [...]

A partir d'une revue systématique de la littérature (29 études, 3 476 patients), cette méta-analyse évalue l'efficacité des interventions psychosociales basées sur le concept de la pleine conscience pour améliorer la santé psychique chez des patients atteints d'un cancer ou ayant survécu à la maladie

The effectiveness of mindfulness-based interventions among cancer patients and survivors: a systematic review and meta-analysis

Xunlin, NG ; Lau, Ying ; Klainin-Yobas, Piyanee

Purpose : Cancer is one of the leading causes of morbidity and mortality worldwide. Cancer negatively affects individuals’ quality of life and overall health. Mindfulness-based interventions appear to be promising in the reduction of cancer-related and treatment-related symptoms. This review aimed to systematically summarize and synthesize the best available evidence concerning the effectiveness of mindfulness-based interventions on anxiety, depression, quality of life, fatigue, stress, [...]

Menée aux Etats-Unis par enquête auprès de 193 adolescents et jeunes adultes atteints d'un cancer (âge :15-29 ans), cette étude analyse les facteurs associés à leur tranquillité d'esprit

Peace of mind among adolescents and young adults with cancer

Gittzus, Jordan A. ; Fasciano, Karen M. ; Block, Susan D. ; Mack, Jennifer W.

Objective : Adolescents and young adults (AYAs) with cancer have high rates of psychological distress and unmet support needs. Peace of mind is an important construct among older cancer patients and parents of children with cancer but has not been explored in AYAs. We sought to evaluate the extent to which AYAs with cancer experience peace of mind and to identify factors associated with greater peace of mind. Methods : We surveyed 193 AYAs with cancer aged 15 to 29 years within 12 weeks of [...]

Menée à Singapour à partir de données portant sur 600 patients atteints d'une tumeur solide de stade avancé, cette étude analyse l'association entre des difficultés financières liées à la maladie, la douleur physique et psychique et leur perception de la qualité des soins

Financial difficulties are associated with greater total pain and suffering among patients with advanced cancer: results from the COMPASS study

Malhotra, Chetna ; Harding, Richard ; Teo, Irene ; Ozdemir, Semra ; Koh, Gerald C. H. ; Neo, Patricia ; Lee, Lai Heng ; Kanesvaran, Ravindran ; Finkelstein, Eric ; Dent, R. A. ; Kumarakulasinghe, N. B. ; Malhotra, R. ; Cheung, Y. B. ; Nadkarni, N. ; Yee, A. C. P. ; Yang, G. M. ; Chan, N. ; Yeo, W. L. ; COMPASS Study team

Background : The Universal Health Coverage goals call for access to affordable palliative care to reduce inequities in “total pain” and suffering. To achieve this, a patient-centred understanding of these inequities is required. Aim : To assess association of total pain and suffering (i.e. physical, psychological, social, and spiritual health outcomes) and perceived health care quality with financial difficulties among stage IV solid malignancy patients. Design : Using baseline data from the [...]

A partir d'une revue systématique de la littérature publiée jusqu'en avril 2019 (51 études), cette méta-analyse évalue l'association entre un stress post-traumatique et la croissance post-traumatique chez des patients atteints d'un cancer ou ayant survécu à la maladie

The Relationship between Post-traumatic Stress and Post-traumatic Growth in Cancer Patients and Survivors: A Systematic Review and Meta-Analysis

Marziliano, Allison ; Tuman, Malwina ; Moyer, Anne

Objective : Research on the relationship between Post-traumatic Stress Disorder (PTSD)/Post-traumatic Stress Symptoms (PTSS) and Post-traumatic Growth (PTG) in cancer patients and survivors is increasing. Method : We conducted a systematic review and meta-analysis of 51 studies that assessed the relationship between PTSD/PTSS and PTG, in cancer patients/survivors. Five databases were searched through April 29, 2019. The purpose of this manuscript is to report: a summary of this literature, the [...]

Menée en France à partir de données portant sur 1 874 patientes ayant survécu à un cancer du sein de stade I à III et travaillant au moment du diagnostic de la maladie, cette étude de cohorte prospective analyse l'effet des traitements anticancéreux et des séquelles associées sur leur retour à l'emploi et leur situation professionnelle

Impact of Breast Cancer Treatment on Employment: Results of a Multicenter Prospective Cohort Study (CANTO)

Agnes Dumas ; Ines Vaz Luis ; Thomas Bovagnet ; Mayssam El Mouhebb ; Antonio Di Meglio ; Sandrine Pinto ; Cecile Charles ; Sarah Dauchy ; Suzette Delaloge ; Patrick Arveux ; Charles Coutant ; Paul Cottu ; Anne Lesur ; Florence Lerebours ; Olivier Trédan ; Laurence Vanlemmens ; Christelle Levy ; Jerome Lemonnier ; Christelle Mesleard ; Fabrice André ; Gwenn Menvielle

PURPOSE : Adverse effects of breast cancer treatment can negatively affect survivors’ work ability. Previous reports lacked detailed clinical data or health-related patient-reported outcomes (PROs) and did not prospectively assess the combined impact of treatment and related sequelae on employment. METHODS : We used a French prospective clinical cohort of patients with stage I-III breast cancer including 1,874 women who were working and ≥ 5 years younger than legal retirement age (≤ 57 years) [...]

Menée dans un contexte italien, cette étude rétrospective analyse le rapport coût-efficacité de 30 médicaments anticancéreux autorisés par l'Agence européenne des médicaments entre 2010 et 2016

Anticancer drug prices and clinical outcomes: a cross-sectional study in Italy

Trotta, Francesco ; Mayer, Flavia ; Barone-Adesi, Francesco ; Esposito, Immacolata ; Punreddy, Ranadhir ; Da Cas, Roberto ; Traversa, Giuseppe ; Perrone, Francesco ; Martini, Nello ; Gyawali, Bishal ; Addis, Antonio

Objective :To investigate whether the prices of new anticancer drugs correlated with their relative benefit despite negotiation. Design :Retrospective cross-sectional study correlating new anticancer drugs prices with clinical outcomes. Setting :We did a retrospective cross-sectional study including all new anticancer drugs approved by the European Medicines Agency (EMA) (2010–2016) and reimbursed in Italy. Main outcome(s) and measure(s) :Information on clinical outcomes—in terms of median [...]

A partir d'une revue systématique de la littérature (6 essais), cette méta-analyse évalue les effets de conseils alimentaires sur l'état nutritionnel de patients souffrant de malnutrition ou étant à risque de malnutrition

The effects of dietary advice on malnutrition in Cancer patients: a systematic review and meta-analysis

Zhang, Fangyuan ; Jin, Yinghui ; Qiang, Wanmin

Background : The effect of dietary advice on malnutrition in cancer patients is unclear. The aim of this systematic review was to evaluate the effects of dietary advice in cancer patients who were malnourished or at risk of malnutrition. Methods : Seven electronic databases were searched for randomized controlled trials (RCTs) of dietary counseling intervention in cancer patients with malnutrition or at risk of malnutrition. The studies were selected according to the inclusion and exclusion [...]

A partir d'une revue systématique d'études qualitatives publiées jusqu'en avril 2019 (101 articles, 1 870 patients), cette étude analyse les expériences de patients pédiatriques (âge : 3-18 ans) concernant la communication avec leur médecin pendant les traitements anticancéreux

Communication during childhood cancer: Systematic review of patient perspectives

Lin, Beryl ; Gutman, Talia ; Hanson, Camilla S. ; Ju, Angela ; Manera, Karine ; Butow, Phyllis ; Cohn, Richard J. ; Dalla-Pozza, Luciano ; Greenzang, Katie A. ; Mack, Jennifer ; Wakefield, Claire E. ; Craig, Jonathan C. ; Tong, Allison

Effective communication is challenging in childhood cancer, where decisions carry unpredictable and life-threatening implications. We aimed to describe patients' experiences of communicating with clinicians during treatment of childhood cancer. A systematic review of qualitative studies to April 2019 was performed. Eligible studies included patients diagnosed with cancer at age ≤ 18 years and reported their perspectives of communicating with clinicians during treatment of childhood cancer. Data [...]

A partir d'une revue systématique de la littérature (13 articles), cette étude analyse les interventions numériques destinées à améliorer la communication relative aux soins entre le patient atteint d'un cancer et le professionnel de santé

Digital interventions to facilitate patient-provider communication in cancer care: a systematic review

Hong, Y. Alicia ; Hossain, Md Mahbub ; Chou, Wen-ying Sylvia

Background : Patient-provider communication is a critical component of cancer care. Digital tools have been applied to facilitate cancer care and patient-provider communication. However, to date, there is no systematic review on this growing body of literature. Objective : To identify the existing digital interventions to improve patient-provider communication among cancer patients and survivors, summarize their characteristics, and synthesize the outcomes of these interventions. Methods : We [...]

Menée par enquête auprès d'un échantillon de la population britannique, cette étude analyse l'effet, sur leur connaissance des symptômes, sur leurs comportements de santé et sur le recours aux examens de dépistage, d'une campagne de communication d'une durée de 4 semaines portant sur le cancer du poumon

Evaluation of a national lung cancer symptom awareness campaign in Wales

McCutchan, Grace ; Smits, Stephanie ; Ironmonger, Lucy ; Slyne, Ciarán ; Boughey, Amanda ; Moffat, Jodie ; Thomas, Rebecca ; Huws, Dyfed Wyn ; Brain, Kate

Background : Lung cancer is the leading cause of cancer mortality in Wales. We conducted a before- and after- study to evaluate the impact of a four-week mass-media campaign on awareness, presentation behaviour and lung cancer outcomes. Methods : Population-representative samples were surveyed for cough symptom recall/recognition and worry about wasting doctors’ time pre-campaign (June 2016; n = 1001) and post-campaign (September 2016; n = 1013). GP cough symptom visits, urgent suspected cancer [...]

Menée aux Pays-Bas à partir de données portant sur 535 patients atteints d'un cancer de stade avancé, cette étude observationnelle analyse l'association entre une consultation avec l'équipe de soins palliatifs et les coûts des soins hospitaliers

The association between palliative care team consultation and hospital costs for patients with advanced cancer: An observational study in 12 Dutch hospitals

Brinkman-Stoppelenburg, Arianne ; Polinder, Suzanne ; Olij, Branko F. ; van den Berg, Barbara ; Gunnink, Nicolette ; Hendriks, Mathijs P. ; van der Linden, Yvette M. ; Nieboer, Daan ; van der Padt-Pruijsten, Annemieke ; Peters, Liesbeth A. ; Roggeveen, Brenda ; Terheggen, Frederiek ; Verhage, Sylvia ; van der Vorst, Maurice J. ; Willemen, Ingrid ; Vergouwe, Yvonne ; van der Heide, Agnes

Background : Early palliative care team consultation has been shown to reduce costs of hospital care. The objective of this study was to investigate the association between palliative care team (PCT) consultation and the content and costs of hospital care in patients with advanced cancer. Material and Methods : A prospective, observational study was conducted in 12 Dutch hospitals. Patients with advanced cancer and an estimated life expectancy of less than 1 year were included. We compared [...]

Menée à partir des données de la base "Open Payments" (OP), cette étude analyse la concordance des informations financières déclarées par des auteurs ayant publié dans le Journal of Clinical Oncology ou ayant présenté des résultats lors de l'ASCO en 2018 avec celles déclarées par les entreprises

Discrepancies in Financial Self-Disclosures and Open Payments Reporting Among Authors of Clinical Oncology Research Studies

Elizabeth Garrett-Mayer ; Melinda W. Kaltenbaugh ; Rebecca Spence ; Suanna S. Bruinooge ; Clifford A. Hudis ; Dina Michels ; Richard L. Schilsky

PURPOSE : Company-reported payments from the Open Payments database (OP) have been compared with self-disclosed financial relationships made by physician authors. Discrepancies have been viewed as under-reporting of financial relationships. Our goal was to perform a systematic comparison to determine sources of discordance between company-reported and self-reported financial relationships. METHODS : Financial disclosures reported by 163 authors and presenters who published in Journal of [...]

A partir d'une revue de la littérature publiée jusqu'en décembre 2016 (8 recommandations), cette étude analyse la qualité et la rigueur méthodologique des recommandations concernant les soins de fin de vie pour les patients atteints d'un cancer

The quality of guidelines on the end-of-life care: a systematic quality appraisal using AGREE II instrument

Irajpour, Alireza ; Hashemi, Maryam ; Taleghani, Fariba

Background : Guidelines are intended to facilitate knowledge translation and evidence-based clinical decision-making, but they vary in methodological rigor and quality. The present study was conducted to assess the quality of guidelines available on end-of-life care in patients with cancer using AGREE II. Methods : A comprehensive search was carried out in EMBASE (Excerpta Medica Database), MEDLINE/PubMed, CINAHL (Cumulative Index to Nursing and Allied Health Literature), and gray literature [...]

A partir d'une revue systématique de la littérature, cette étude propose des normes de bonnes pratiques, centrées sur le patient, concernant l'accès aux médicaments anticancéreux et aux soins de support

Patient-Centered Standards for Medically Integrated Dispensing: ASCO/NCODA Standards

Melissa S. Dillmon ; Erin B. Kennedy ; Mary K. Anderson ; Michael Brodersen ; Howard Cohen ; Steven L. D′Amato ; Patty Davis ; Gury Doshi ; Stuart Genschaw ; Issam Makhoul ; Wayne Ormsby ; Rajiv Panikkar ; Eileen Peng ; Luis E. Raez ; Ellen A. Ronnen ; Bill Wimbiscus ; Michael Reff

PURPOSE : To provide standards for medically integrated dispensing of oral anticancer drugs and supportive care medications. METHODS : An Expert Panel was formed, and a systematic review of the literature on patient-centered best practices for the delivery of oral anticancer and supportive care drugs was performed to April 2019 using PubMed and Google Scholar. Available patient-centered standards, including one previously developed by the National Community Oncology Dispensing Association [...]